PMC:7386785 / 18582-19888 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7386785","sourcedb":"PMC","sourceid":"7386785","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7386785","text":"Target condition being diagnosed\nCOVID‐19 is the disease caused by infection with the SARS‐CoV‐2 virus. SARS‐CoV‐2 infection is diagnosed with reverse transcription polymerase chain reaction (RT‐PCR), which is a test that detects the virus' genetic material, with imaging to identify lung abnormalities and with clinical signs and symptoms.\nSARS‐CoV‐2 infection can be asymptomatic (no symptoms); mild or moderate; severe (causing breathlessness and increased respiratory rate indicative of pneumonia and oxygen need); or critical (requiring intensive support due to severe acute respiratory syndrome (SARS) or acute respiratory distress syndrome (ARDS), shock or other organ dysfunction). People with COVID‐19 pneumonia (severe or critical disease), require different patient management, which makes it important to distinguish between mild or moderate COVID‐19 disease and COVID‐19 pneumonia.\nIn this review, we will examine the diagnostic value of signs and symptoms for symptomatic SARS‐CoV‐2 infection, which includes mild or moderate COVID‐19 disease and COVID‐19 pneumonia.\nIn planning review updates, we will consider the potential addition of another grouping, which is a subset of the above:\nwhether tests exist that identify people requiring respiratory support (SARS or ARDS) or intensive 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