PMC:7376974 / 40442-40864 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T180","span":{"begin":117,"end":129},"obj":"Body_part"}],"attributes":[{"id":"A180","pred":"fma_id","subj":"T180","obj":"http://purl.org/sig/ont/fma/fma82744"}],"text":"In this case, the molecule was synthesized with a C60 tridecafullerene bearing α(1,2)mannobioside.70 The use of this disaccharide was already investigated, showing an increase of affinity with DC-sign receptors by a factor of 3–4.71 The synthetic strategy exploited also the use of strain-promoted copper-free cycloaddition of azides to alkynes (SPAAC) for the coupling of the core fullerene to the surrounding fullerenes."}

{"project":"LitCovid-PubTator","denotations":[{"id":"670","span":{"begin":193,"end":200},"obj":"Gene"},{"id":"678","span":{"begin":50,"end":70},"obj":"Chemical"},{"id":"679","span":{"begin":79,"end":97},"obj":"Chemical"},{"id":"680","span":{"begin":117,"end":129},"obj":"Chemical"},{"id":"681","span":{"begin":298,"end":304},"obj":"Chemical"},{"id":"682","span":{"begin":327,"end":333},"obj":"Chemical"},{"id":"683","span":{"begin":337,"end":344},"obj":"Chemical"},{"id":"684","span":{"begin":346,"end":351},"obj":"Chemical"},{"id":"685","span":{"begin":382,"end":391},"obj":"Chemical"},{"id":"686","span":{"begin":411,"end":421},"obj":"Chemical"}],"attributes":[{"id":"A670","pred":"tao:has_database_id","subj":"670","obj":"Gene:30835"},{"id":"A680","pred":"tao:has_database_id","subj":"680","obj":"MESH:D004187"},{"id":"A681","pred":"tao:has_database_id","subj":"681","obj":"MESH:D003300"},{"id":"A682","pred":"tao:has_database_id","subj":"682","obj":"MESH:D001386"},{"id":"A683","pred":"tao:has_database_id","subj":"683","obj":"MESH:D000480"},{"id":"A685","pred":"tao:has_database_id","subj":"685","obj":"MESH:D037741"},{"id":"A686","pred":"tao:has_database_id","subj":"686","obj":"MESH:D037741"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In this case, the molecule was synthesized with a C60 tridecafullerene bearing α(1,2)mannobioside.70 The use of this disaccharide was already investigated, showing an increase of affinity with DC-sign receptors by a factor of 3–4.71 The synthetic strategy exploited also the use of strain-promoted copper-free cycloaddition of azides to alkynes (SPAAC) for the coupling of the core fullerene to the surrounding fullerenes."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T374","span":{"begin":48,"end":49},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T375","span":{"begin":214,"end":215},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"In this case, the molecule was synthesized with a C60 tridecafullerene bearing α(1,2)mannobioside.70 The use of this disaccharide was already investigated, showing an increase of affinity with DC-sign receptors by a factor of 3–4.71 The synthetic strategy exploited also the use of strain-promoted copper-free cycloaddition of azides to alkynes (SPAAC) for the coupling of the core fullerene to the surrounding fullerenes."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T517","span":{"begin":18,"end":26},"obj":"Chemical"},{"id":"T518","span":{"begin":117,"end":129},"obj":"Chemical"},{"id":"T519","span":{"begin":298,"end":304},"obj":"Chemical"},{"id":"T521","span":{"begin":327,"end":333},"obj":"Chemical"},{"id":"T522","span":{"begin":337,"end":344},"obj":"Chemical"},{"id":"T523","span":{"begin":382,"end":391},"obj":"Chemical"},{"id":"T524","span":{"begin":411,"end":421},"obj":"Chemical"}],"attributes":[{"id":"A517","pred":"chebi_id","subj":"T517","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A518","pred":"chebi_id","subj":"T518","obj":"http://purl.obolibrary.org/obo/CHEBI_36233"},{"id":"A519","pred":"chebi_id","subj":"T519","obj":"http://purl.obolibrary.org/obo/CHEBI_28694"},{"id":"A520","pred":"chebi_id","subj":"T519","obj":"http://purl.obolibrary.org/obo/CHEBI_30052"},{"id":"A521","pred":"chebi_id","subj":"T521","obj":"http://purl.obolibrary.org/obo/CHEBI_22680"},{"id":"A522","pred":"chebi_id","subj":"T522","obj":"http://purl.obolibrary.org/obo/CHEBI_22339"},{"id":"A523","pred":"chebi_id","subj":"T523","obj":"http://purl.obolibrary.org/obo/CHEBI_33416"},{"id":"A524","pred":"chebi_id","subj":"T524","obj":"http://purl.obolibrary.org/obo/CHEBI_33416"}],"text":"In this case, the molecule was synthesized with a C60 tridecafullerene bearing α(1,2)mannobioside.70 The use of this disaccharide was already investigated, showing an increase of affinity with DC-sign receptors by a factor of 3–4.71 The synthetic strategy exploited also the use of strain-promoted copper-free cycloaddition of azides to alkynes (SPAAC) for the coupling of the core fullerene to the surrounding fullerenes."}

{"project":"LitCovid-sentences","denotations":[{"id":"T257","span":{"begin":0,"end":422},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In this case, the molecule was synthesized with a C60 tridecafullerene bearing α(1,2)mannobioside.70 The use of this disaccharide was already investigated, showing an increase of affinity with DC-sign receptors by a factor of 3–4.71 The synthetic strategy exploited also the use of strain-promoted copper-free cycloaddition of azides to alkynes (SPAAC) for the coupling of the core fullerene to the surrounding fullerenes."}

{"project":"2_test","denotations":[{"id":"32667191-31469952-153333","span":{"begin":98,"end":100},"obj":"31469952"},{"id":"32667191-17150970-153334","span":{"begin":230,"end":232},"obj":"17150970"}],"text":"In this case, the molecule was synthesized with a C60 tridecafullerene bearing α(1,2)mannobioside.70 The use of this disaccharide was already investigated, showing an increase of affinity with DC-sign receptors by a factor of 3–4.71 The synthetic strategy exploited also the use of strain-promoted copper-free cycloaddition of azides to alkynes (SPAAC) for the coupling of the core fullerene to the surrounding fullerenes."}