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PMC:7376845 / 120-1817 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 314-318 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T2 423-435 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T3 439-446 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T4 617-624 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T5 679-686 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T6 852-859 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T7 888-895 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T8 933-938 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T9 950-955 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T10 990-997 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T11 1113-1120 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T12 1187-1194 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T13 1369-1376 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T14 1400-1404 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T15 1464-1471 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T16 1495-1500 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
17 353-384 Gene denotes angiotensin-converting enzyme 2 Gene:59272
18 386-390 Gene denotes ACE2 Gene:59272
19 437-446 Gene denotes S protein
20 470-474 Gene denotes ACE2 Gene:59272
21 13-30 Species denotes novel coronavirus Tax:2697049
22 32-42 Species denotes SARS-CoV-2 Tax:2697049
23 124-129 Species denotes human Tax:9606
24 170-178 Species denotes SARS-CoV Tax:694009
25 331-341 Species denotes SARS-CoV-2 Tax:2697049
26 406-414 Species denotes SARS-CoV Tax:694009
27 496-506 Species denotes SARS-CoV-2 Tax:2697049
28 88-96 Disease denotes COVID-19 MESH:C000657245
29 130-140 Disease denotes infections MESH:D007239
33 615-616 Gene denotes S Gene:43740568
34 628-636 Species denotes SARS-CoV Tax:694009
35 539-549 Species denotes SARS-CoV-2 Tax:2697049
45 1111-1120 Gene denotes S protein
46 666-676 Species denotes SARS-CoV-2 Tax:2697049
47 720-728 Species denotes SARS-CoV Tax:694009
48 788-801 Species denotes coronaviruses Tax:11118
49 839-847 Species denotes SARS-CoV Tax:694009
50 868-878 Species denotes SARS-CoV-2 Tax:2697049
51 732-764 Disease denotes Middle East respiratory syndrome MESH:D018352
52 766-770 Disease denotes MERS MESH:D018352
53 913-932 Disease denotes SARS-CoV-2 infected MESH:C000657245
63 1174-1182 Species denotes SARS-CoV Tax:694009
64 1218-1228 Species denotes SARS-CoV-2 Tax:2697049
65 1249-1254 Species denotes human Tax:9606
66 1267-1280 Species denotes coronaviruses Tax:11118
67 1287-1293 Species denotes murine Tax:10090
68 1356-1366 Species denotes SARS-CoV-2 Tax:2697049
69 1390-1399 Species denotes mammalian Tax:9606
70 1240-1244 Disease denotes MERS MESH:D018352
71 1480-1494 Disease denotes CoV-2-infected MESH:C000657245
74 1619-1629 Species denotes SARS-CoV-2 Tax:2697049
75 1688-1696 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T5 32-40 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T6 32-36 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T7 88-96 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 130-140 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T9 170-178 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T10 170-174 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T11 236-269 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T12 271-275 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T13 331-339 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 331-335 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T15 406-414 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 406-410 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T17 496-504 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T18 496-500 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T19 539-547 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 539-543 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T21 628-636 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T22 628-632 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T23 666-674 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T24 666-670 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T25 720-728 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 720-724 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T27 776-787 Disease denotes common-cold http://purl.obolibrary.org/obo/MONDO_0005709
T28 839-847 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 839-843 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T30 868-876 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T31 868-872 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T32 913-921 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T33 913-917 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T34 1174-1182 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 1174-1178 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T36 1218-1226 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T37 1218-1222 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T38 1255-1266 Disease denotes common-cold http://purl.obolibrary.org/obo/MONDO_0005709
T39 1356-1364 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 1356-1360 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T41 1475-1483 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T42 1475-1479 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T43 1619-1627 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 1619-1623 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T45 1688-1696 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T3 11-12 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T4 98-101 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T5 124-129 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T6 314-318 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T7 509-512 http://purl.obolibrary.org/obo/PR_000001343 denotes Aim
T8 901-907 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T9 933-938 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T10 950-955 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T11 1001-1002 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 1019-1021 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T13 1019-1021 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T14 1160-1162 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T15 1160-1162 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T16 1249-1254 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T17 1400-1410 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T18 1495-1500 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T19 1528-1529 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T2 353-364 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T3 423-435 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T4 439-446 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T5 617-624 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T6 679-686 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T7 852-859 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T8 888-895 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T9 990-997 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T10 1019-1021 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T11 1113-1120 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T12 1160-1162 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T13 1187-1194 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T14 1369-1376 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T15 1464-1471 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-10 Sentence denotes Background
T4 11-141 Sentence denotes A novel coronavirus, SARS-CoV-2, which emerged at the end of 2019 and causes COVID-19, has resulted in worldwide human infections.
T5 142-392 Sentence denotes While genetically distinct, SARS-CoV-1, the aetiological agent responsible for an outbreak of severe acute respiratory syndrome (SARS) in 2002–2003, utilises the same host cell receptor as SARS-CoV-2 for entry: angiotensin-converting enzyme 2 (ACE2).
T6 393-507 Sentence denotes Parts of the SARS-CoV-1 spike glycoprotein (S protein), which interacts with ACE2, appear conserved in SARS-CoV-2.
T7 509-512 Sentence denotes Aim
T8 513-652 Sentence denotes The cross-reactivity with SARS-CoV-2 of monoclonal antibodies (mAbs) previously generated against the S protein of SARS-CoV-1 was assessed.
T9 654-661 Sentence denotes Methods
T10 662-802 Sentence denotes The SARS-CoV-2 S protein sequence was aligned to those of SARS-CoV-1, Middle East respiratory syndrome (MERS) and common-cold coronaviruses.
T11 803-1030 Sentence denotes Abilities of mAbs generated against SARS-CoV-1 S protein to bind SARS-CoV-2 or its S protein were tested with SARS-CoV-2 infected cells as well as cells expressing either the full length protein or a fragment of its S2 subunit.
T12 1031-1121 Sentence denotes Quantitative ELISA was also performed to compare binding of mAbs to recombinant S protein.
T13 1123-1130 Sentence denotes Results
T14 1131-1281 Sentence denotes An immunogenic domain in the S2 subunit of SARS-CoV-1 S protein is highly conserved in SARS-CoV-2 but not in MERS and human common-cold coronaviruses.
T15 1282-1411 Sentence denotes Four murine mAbs raised against this immunogenic fragment could recognise SARS-CoV-2 S protein expressed in mammalian cell lines.
T16 1412-1552 Sentence denotes In particular, mAb 1A9 was demonstrated to detect S protein in SARS-CoV-2-infected cells and is suitable for use in a sandwich ELISA format.
T17 1554-1564 Sentence denotes Conclusion
T18 1565-1697 Sentence denotes The cross-reactive mAbs may serve as useful tools for SARS-CoV-2 research and for the development of diagnostic assays for COVID-19.