PMC:7373848 / 12214-12733 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T191","span":{"begin":7,"end":24},"obj":"Body_part"},{"id":"T192","span":{"begin":19,"end":24},"obj":"Body_part"},{"id":"T193","span":{"begin":115,"end":126},"obj":"Body_part"},{"id":"T194","span":{"begin":259,"end":268},"obj":"Body_part"},{"id":"T195","span":{"begin":300,"end":311},"obj":"Body_part"},{"id":"T196","span":{"begin":313,"end":315},"obj":"Body_part"},{"id":"T197","span":{"begin":321,"end":325},"obj":"Body_part"},{"id":"T198","span":{"begin":321,"end":323},"obj":"Body_part"},{"id":"T199","span":{"begin":348,"end":372},"obj":"Body_part"}],"attributes":[{"id":"A191","pred":"fma_id","subj":"T191","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A192","pred":"fma_id","subj":"T192","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A193","pred":"fma_id","subj":"T193","obj":"http://purl.org/sig/ont/fma/fma63916"},{"id":"A194","pred":"fma_id","subj":"T194","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A195","pred":"fma_id","subj":"T195","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A196","pred":"fma_id","subj":"T196","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A197","pred":"fma_id","subj":"T197","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A198","pred":"fma_id","subj":"T198","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A199","pred":"fma_id","subj":"T199","obj":"http://purl.org/sig/ont/fma/fma63171"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T75","span":{"begin":115,"end":126},"obj":"Body_part"}],"attributes":[{"id":"A75","pred":"uberon_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/UBERON_0001986"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"149","span":{"begin":34,"end":46},"obj":"Disease"},{"id":"153","span":{"begin":270,"end":298},"obj":"Gene"},{"id":"154","span":{"begin":300,"end":319},"obj":"Gene"},{"id":"155","span":{"begin":434,"end":446},"obj":"Chemical"}],"attributes":[{"id":"A149","pred":"tao:has_database_id","subj":"149","obj":"MESH:D007249"},{"id":"A153","pred":"tao:has_database_id","subj":"153","obj":"Gene:7124"},{"id":"A154","pred":"tao:has_database_id","subj":"154","obj":"Gene:3586"},{"id":"A155","pred":"tao:has_database_id","subj":"155","obj":"MESH:D009569"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T40","span":{"begin":34,"end":46},"obj":"Disease"}],"attributes":[{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T215","span":{"begin":7,"end":24},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T216","span":{"begin":115,"end":126},"obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"T217","span":{"begin":143,"end":144},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T218","span":{"begin":165,"end":172},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T219","span":{"begin":225,"end":232},"obj":"http://purl.obolibrary.org/obo/SO_0000418"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T62","span":{"begin":313,"end":315},"obj":"Chemical"},{"id":"T64","span":{"begin":321,"end":323},"obj":"Chemical"},{"id":"T66","span":{"begin":335,"end":342},"obj":"Chemical"},{"id":"T67","span":{"begin":348,"end":384},"obj":"Chemical"},{"id":"T68","span":{"begin":348,"end":372},"obj":"Chemical"},{"id":"T69","span":{"begin":361,"end":372},"obj":"Chemical"},{"id":"T70","span":{"begin":373,"end":384},"obj":"Chemical"},{"id":"T71","span":{"begin":434,"end":446},"obj":"Chemical"},{"id":"T72","span":{"begin":441,"end":446},"obj":"Chemical"}],"attributes":[{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A63","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A64","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A65","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A66","pred":"chebi_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_48705"},{"id":"A67","pred":"chebi_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/CHEBI_47775"},{"id":"A68","pred":"chebi_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_39025"},{"id":"A69","pred":"chebi_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/CHEBI_6495"},{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_16113"},{"id":"A71","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_16480"},{"id":"A72","pred":"chebi_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/CHEBI_25741"},{"id":"A73","pred":"chebi_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/CHEBI_29356"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T46","span":{"begin":34,"end":46},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T47","span":{"begin":283,"end":289},"obj":"http://purl.obolibrary.org/obo/GO_0040007"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T79","span":{"begin":0,"end":47},"obj":"Sentence"},{"id":"T80","span":{"begin":48,"end":201},"obj":"Sentence"},{"id":"T81","span":{"begin":202,"end":385},"obj":"Sentence"},{"id":"T82","span":{"begin":386,"end":519},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T410","span":{"begin":7,"end":18},"obj":"UBERON:0001986;CL:0000115"},{"id":"T411","span":{"begin":19,"end":24},"obj":"CL:0000115"},{"id":"T412","span":{"begin":25,"end":33},"obj":"GO:0065007"},{"id":"T413","span":{"begin":115,"end":126},"obj":"UBERON:0001986"},{"id":"T414","span":{"begin":131,"end":139},"obj":"GO:0065007"},{"id":"T415","span":{"begin":156,"end":164},"obj":"GO:0005576"},{"id":"T416","span":{"begin":177,"end":190},"obj":"GO:0005622"},{"id":"T417","span":{"begin":191,"end":200},"obj":"CHEBI:67079;CHEBI:67079"},{"id":"T418","span":{"begin":270,"end":298},"obj":"PR:000000046"},{"id":"T419","span":{"begin":326,"end":342},"obj":"CHEBI:48561;CHEBI:48561"},{"id":"T420","span":{"begin":373,"end":384},"obj":"CHEBI:47775;CHEBI:47775"},{"id":"T421","span":{"begin":434,"end":446},"obj":"CHEBI:16480;CHEBI:16480"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}

{"project":"2_test","denotations":[{"id":"32700024-11348996-64991460","span":{"begin":511,"end":513},"obj":"11348996"},{"id":"32700024-1675786-64991461","span":{"begin":515,"end":517},"obj":"1675786"}],"text":"How do endothelial cells regulate inflammation?\nThe anti-inflammatory properties that characterize normal vascular endothelium are governed by a variety of external signals and intracellular mediators. The operative external signals include anti-inflammatory cytokines, transforming growth factor β, interleukin (IL)-10, IL-1 receptor agonist, and high-density lipoprotein cholesterol. Laminar shear stress, through the generation of nitric oxide, is of particular importance in maintaining inflammoresistance [19, 20]."}