PMC:7358770 / 6609-7735
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 617-626 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T2 | 617-626 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
| T3 | 708-719 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T4 | 759-766 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T5 | 759-766 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T6 | 768-770 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | HP |
| T7 | 855-865 | https://glytoucan.org/Structures/Glycans/G00017MO | denotes | hyaluronan |
| T8 | 867-869 | https://glytoucan.org/Structures/Glycans/G00017MO | denotes | HA |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T40 | 20-35 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T41 | 51-69 | Body_part | denotes | glycosaminoglycans | http://purl.org/sig/ont/fma/fma63011 |
| T42 | 71-75 | Body_part | denotes | GAGs | http://purl.org/sig/ont/fma/fma63011 |
| T43 | 85-100 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T44 | 123-138 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T45 | 151-166 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T46 | 198-202 | Body_part | denotes | GAGs | http://purl.org/sig/ont/fma/fma63011 |
| T47 | 232-247 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T48 | 288-300 | Body_part | denotes | compartments | http://purl.org/sig/ont/fma/fma76577 |
| T49 | 302-314 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
| T50 | 302-306 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T51 | 466-470 | Body_part | denotes | GAGs | http://purl.org/sig/ont/fma/fma63011 |
| T52 | 503-515 | Body_part | denotes | disaccharide | http://purl.org/sig/ont/fma/fma82744 |
| T53 | 587-602 | Body_part | denotes | glucuronic acid | http://purl.org/sig/ont/fma/fma82798 |
| T54 | 604-615 | Body_part | denotes | glucosamine | http://purl.org/sig/ont/fma/fma82797 |
| T55 | 617-626 | Body_part | denotes | galactose | http://purl.org/sig/ont/fma/fma82794 |
| T56 | 630-643 | Body_part | denotes | galactosamine | http://purl.org/sig/ont/fma/fma82792 |
| T57 | 644-659 | Body_part | denotes | monosaccharides | http://purl.org/sig/ont/fma/fma82741 |
| T58 | 688-692 | Body_part | denotes | GAGs | http://purl.org/sig/ont/fma/fma63011 |
| T59 | 708-727 | Body_part | denotes | chondroitin sulfate | http://purl.org/sig/ont/fma/fma82837 |
| T60 | 729-731 | Body_part | denotes | CS | http://purl.org/sig/ont/fma/fma284995|http://purl.org/sig/ont/fma/fma82837 |
| T62 | 734-749 | Body_part | denotes | heparan sulfate | http://purl.org/sig/ont/fma/fma63023 |
| T63 | 751-753 | Body_part | denotes | HS | http://purl.org/sig/ont/fma/fma63023 |
| T64 | 759-766 | Body_part | denotes | heparin | http://purl.org/sig/ont/fma/fma82839 |
| T65 | 768-770 | Body_part | denotes | HP | http://purl.org/sig/ont/fma/fma82839 |
| T66 | 782-789 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
| T67 | 809-812 | Body_part | denotes | GAG | http://purl.org/sig/ont/fma/fma63011 |
| T68 | 855-865 | Body_part | denotes | hyaluronan | http://purl.org/sig/ont/fma/fma63014 |
| T69 | 867-869 | Body_part | denotes | HA | http://purl.org/sig/ont/fma/fma63014 |
| T70 | 932-936 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
| T71 | 981-985 | Body_part | denotes | GAGs | http://purl.org/sig/ont/fma/fma63011 |
| T72 | 1040-1055 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T73 | 1057-1061 | Body_part | denotes | GAGs | http://purl.org/sig/ont/fma/fma63011 |
| T74 | 1070-1085 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T75 | 1109-1124 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 209 | 1040-1055 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 210 | 1070-1085 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 211 | 1109-1124 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 232 | 20-35 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 233 | 51-69 | Chemical | denotes | glycosaminoglycans | MESH:D006025 |
| 234 | 85-100 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 235 | 123-138 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 236 | 151-166 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 237 | 232-247 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 238 | 494-515 | Chemical | denotes | O-linked disaccharide | |
| 239 | 572-585 | Chemical | denotes | iduronic acid | MESH:D007067 |
| 240 | 587-602 | Chemical | denotes | glucuronic acid | MESH:D020723 |
| 241 | 604-615 | Chemical | denotes | glucosamine | MESH:D005944 |
| 242 | 617-626 | Chemical | denotes | galactose | MESH:D005690 |
| 243 | 630-659 | Chemical | denotes | galactosamine monosaccharides | |
| 244 | 708-727 | Chemical | denotes | chondroitin sulfate | MESH:D002809 |
| 245 | 729-731 | Chemical | denotes | CS | MESH:D002809 |
| 246 | 734-749 | Chemical | denotes | heparan sulfate | MESH:D006497 |
| 247 | 751-753 | Chemical | denotes | HS | MESH:D006497 |
| 248 | 768-770 | Chemical | denotes | HP | MESH:D006493 |
| 249 | 809-812 | Chemical | denotes | GAG | MESH:D006025 |
| 250 | 855-865 | Chemical | denotes | hyaluronan | MESH:D006820 |
| 251 | 867-869 | Chemical | denotes | HA | MESH:D006820 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T62 | 302-306 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T63 | 461-463 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T64 | 555-556 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T65 | 768-770 | http://purl.obolibrary.org/obo/CLO_0003797 | denotes | HP |
| T66 | 768-770 | http://purl.obolibrary.org/obo/PR_000008725 | denotes | HP |
| T67 | 775-781 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T75 | 20-35 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T76 | 51-69 | Chemical | denotes | glycosaminoglycans | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T77 | 71-75 | Chemical | denotes | GAGs | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T78 | 85-100 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T79 | 123-138 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T80 | 151-166 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T81 | 198-202 | Chemical | denotes | GAGs | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T82 | 232-247 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T83 | 379-388 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T84 | 466-470 | Chemical | denotes | GAGs | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T85 | 503-515 | Chemical | denotes | disaccharide | http://purl.obolibrary.org/obo/CHEBI_36233 |
| T86 | 572-585 | Chemical | denotes | iduronic acid | http://purl.obolibrary.org/obo/CHEBI_24769 |
| T87 | 581-585 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T88 | 587-602 | Chemical | denotes | glucuronic acid | http://purl.obolibrary.org/obo/CHEBI_24298 |
| T89 | 598-602 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T90 | 604-615 | Chemical | denotes | glucosamine | http://purl.obolibrary.org/obo/CHEBI_5417 |
| T91 | 617-626 | Chemical | denotes | galactose | http://purl.obolibrary.org/obo/CHEBI_28260 |
| T92 | 630-643 | Chemical | denotes | galactosamine | http://purl.obolibrary.org/obo/CHEBI_24156 |
| T93 | 644-659 | Chemical | denotes | monosaccharides | http://purl.obolibrary.org/obo/CHEBI_35381 |
| T94 | 688-692 | Chemical | denotes | GAGs | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T95 | 708-727 | Chemical | denotes | chondroitin sulfate | http://purl.obolibrary.org/obo/CHEBI_37397 |
| T96 | 720-727 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
| T97 | 729-731 | Chemical | denotes | CS | http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_37397 |
| T99 | 734-749 | Chemical | denotes | heparan sulfate | http://purl.obolibrary.org/obo/CHEBI_28815 |
| T100 | 734-741 | Chemical | denotes | heparan | http://purl.obolibrary.org/obo/CHEBI_24500 |
| T101 | 742-749 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
| T102 | 751-753 | Chemical | denotes | HS | http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815 |
| T104 | 759-766 | Chemical | denotes | heparin | http://purl.obolibrary.org/obo/CHEBI_28304 |
| T105 | 768-770 | Chemical | denotes | HP | http://purl.obolibrary.org/obo/CHEBI_74055|http://purl.obolibrary.org/obo/CHEBI_28304 |
| T107 | 809-812 | Chemical | denotes | GAG | http://purl.obolibrary.org/obo/CHEBI_143889 |
| T108 | 855-865 | Chemical | denotes | hyaluronan | http://purl.obolibrary.org/obo/CHEBI_132153|http://purl.obolibrary.org/obo/CHEBI_16336 |
| T110 | 867-869 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924|http://purl.obolibrary.org/obo/CHEBI_132153 |
| T112 | 981-985 | Chemical | denotes | GAGs | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T113 | 1040-1055 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T114 | 1057-1061 | Chemical | denotes | GAGs | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T115 | 1070-1085 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T116 | 1109-1124 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T7 | 406-424 | http://purl.obolibrary.org/obo/GO_0009987 | denotes | cellular processes |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32679328-19090915-48281239 | 661-663 | 19090915 | denotes | 23 |
| 32679328-24121191-48281240 | 664-666 | 24121191 | denotes | 24 |
| 32679328-31629041-48281241 | 804-806 | 31629041 | denotes | 25 |
| 32679328-19758573-48281242 | 938-940 | 19758573 | denotes | 26 |
| 32679328-28739506-48281243 | 941-943 | 28739506 | denotes | 27 |
| T61777 | 661-663 | 19090915 | denotes | 23 |
| T17748 | 664-666 | 24121191 | denotes | 24 |
| T44813 | 804-806 | 31629041 | denotes | 25 |
| T39133 | 938-940 | 19758573 | denotes | 26 |
| T10578 | 941-943 | 28739506 | denotes | 27 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T44 | 0-197 | Sentence | denotes | The main sources of polysaccharides are endogenous glycosaminoglycans (GAGs), Marine polysaccharides and terrestrial plant polysaccharides, especially polysaccharides from Chinese herbal medicines. |
| T45 | 198-465 | Sentence | denotes | GAGs are naturally-derived linear polysaccharides that are expressed in the intracellular compartments, cell surface, and extracellular environments, and they interact with various molecules to regulate many cellular processes associated with health and disease [22]. |
| T46 | 466-668 | Sentence | denotes | GAGs are comprised distinct O-linked disaccharide units, which are typically composed of a combination of iduronic acid, glucuronic acid, glucosamine, galactose or galactosamine monosaccharides [23,24]. |
| T47 | 669-808 | Sentence | denotes | The widely studied GAGs mainly include chondroitin sulfate (CS), heparan sulfate (HS) and heparin (HP) in animal tissues (Fig. 3 ) [22,25]. |
| T48 | 809-945 | Sentence | denotes | GAG chains are in most cases sulfated, except hyaluronan (HA) (Fig. 3), which are biodegradable and non-immunogenic in the body [26,27]. |
| T49 | 946-1006 | Sentence | denotes | The chemical structures of typical GAGs are shown in Fig. 3. |
| T50 | 1007-1126 | Sentence | denotes | Fig. 3 The structures of several polysaccharides (GAGs, marine polysaccharides, and terrestrial plant polysaccharides). |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T2 | 708-719 | GlycoEpitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 734-749 | GlycoEpitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
| T4 | 751-753 | GlycoEpitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T190 | 20-35 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T191 | 51-69 | CHEBI:18085;CHEBI:18085 | denotes | glycosaminoglycans |
| T192 | 85-100 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T193 | 117-122 | NCBITaxon:3193 | denotes | plant |
| T194 | 123-138 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T195 | 151-166 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T196 | 232-247 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T197 | 257-266 | GO:0010467 | denotes | expressed |
| T198 | 274-287 | GO:0005622 | denotes | intracellular |
| T199 | 302-314 | GO:0009986 | denotes | cell surface |
| T200 | 320-333 | GO:0005576 | denotes | extracellular |
| T201 | 379-388 | CHEBI:36357;CHEBI:36357 | denotes | molecules |
| T202 | 392-400 | GO:0065007 | denotes | regulate |
| T203 | 406-424 | GO:0009987 | denotes | cellular processes |
| T204 | 494-495 | GO:0000805 | denotes | O |
| T205 | 503-515 | CHEBI:36233;CHEBI:36233 | denotes | disaccharide |
| T206 | 572-585 | CHEBI:24769;CHEBI:24769 | denotes | iduronic acid |
| T207 | 587-602 | CHEBI:24298;CHEBI:24298 | denotes | glucuronic acid |
| T208 | 604-615 | CHEBI:24271;CHEBI:24271 | denotes | glucosamine |
| T209 | 617-626 | CHEBI:28260;CHEBI:28260 | denotes | galactose |
| T210 | 630-643 | CHEBI:24156;CHEBI:24156 | denotes | galactosamine |
| T211 | 644-659 | CHEBI:35381;CHEBI:35381 | denotes | monosaccharides |
| T212 | 708-727 | CHEBI:37397;CHEBI:37397 | denotes | chondroitin sulfate |
| T213 | 734-749 | CHEBI:28815;CHEBI:28815 | denotes | heparan sulfate |
| T214 | 759-766 | CHEBI:24505;CHEBI:24505 | denotes | heparin |
| T215 | 775-781 | NCBITaxon:33208 | denotes | animal |
| T216 | 782-789 | UBERON:0000479 | denotes | tissues |
| T217 | 855-865 | CHEBI:24751;CHEBI:24751 | denotes | hyaluronan |
| T218 | 913-924 | CHEBI:60816;CHEBI:60816 | denotes | immunogenic |
| T219 | 1040-1055 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T220 | 1070-1085 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T221 | 1103-1108 | NCBITaxon:3193 | denotes | plant |
| T222 | 1109-1124 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T87057 | 17-22 | CHEBI:35701;CHEBI:35701 | denotes | of po |
| T82681 | 23-30 | CHEBI:16189;CHEBI:16189 | denotes | ysaccha |
| T47338 | 222-233 | CHEBI:3435;CHEBI:3435 | denotes | ed linear p |
| T44273 | 263-269 | CHEBI:33984;CHEBI:33984 | denotes | sed in |
| T61444 | 292-306 | CHEBI:18154;CHEBI:18154 | denotes | artments, cell |
| T60217 | 328-333 | NCBITaxon:2870 | denotes | lular |
| T49078 | 374-381 | CHEBI:16189;CHEBI:16189 | denotes | ious mo |
| T32775 | 382-388 | CHEBI:24433;CHEBI:24433 | denotes | ecules |
| T20658 | 414-422 | CHEBI:15936;CHEBI:15936 | denotes | process |
| T21573 | 425-433 | CHEBI:16024;CHEBI:16024 | denotes | associat |
| T78225 | 435-446 | CHEBI:12936;CHEBI:12936 | denotes | with healt |
| T98683 | 452-469 | CHEBI:4178;CHEBI:4178 | denotes | disease [22]. GAG |
| T57864 | 549-555 | CHEBI:37527;CHEBI:37527 | denotes | ed of |
| T60445 | 567-581 | CHEBI:18154;CHEBI:18154 | denotes | n of iduronic |
| T25781 | 642-656 | CHEBI:16224;CHEBI:16224 | denotes | e monosacchari |
| T36643 | 670-679 | CHEBI:22424;CHEBI:22424 | denotes | he widely |
| T43770 | 680-684 | CHEBI:28378;CHEBI:28378 | denotes | stud |
| T11961 | 719-726 | CHEBI:16189;CHEBI:16189 | denotes | sulfat |
| T53396 | 789-803 | CHEBI:18154;CHEBI:18154 | denotes | (Fig. 3 ) [22 |
| T23628 | 908-919 | NCBITaxon:20400 | denotes | non-immuno |
| T33919 | 920-934 | CHEBI:18154;CHEBI:18154 | denotes | enic in the bo |
| T6683 | 1037-1060 | NCBITaxon:649199 | denotes | al polysaccharides (GAG |
| T33668 | 1083-1090 | CHEBI:17234;CHEBI:17234 | denotes | es, and |
| T97311 | 1092-1099 | CHEBI:37684;CHEBI:37684 | denotes | errestr |
| T2529 | 1101-1110 | CHEBI:17634;CHEBI:17634 | denotes | l plant p |
MyTest
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 209 | 1040-1055 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 210 | 1070-1085 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 211 | 1109-1124 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 232 | 20-35 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 233 | 51-69 | Chemical | denotes | glycosaminoglycans | MESH:D006025 |
| 234 | 85-100 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 235 | 123-138 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 236 | 151-166 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 237 | 232-247 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 238 | 494-515 | Chemical | denotes | O-linked disaccharide | |
| 239 | 572-585 | Chemical | denotes | iduronic acid | MESH:D007067 |
| 240 | 587-602 | Chemical | denotes | glucuronic acid | MESH:D020723 |
| 241 | 604-615 | Chemical | denotes | glucosamine | MESH:D005944 |
| 242 | 617-626 | Chemical | denotes | galactose | MESH:D005690 |
| 243 | 630-659 | Chemical | denotes | galactosamine monosaccharides | |
| 244 | 708-727 | Chemical | denotes | chondroitin sulfate | MESH:D002809 |
| 245 | 729-731 | Chemical | denotes | CS | MESH:D002809 |
| 246 | 734-749 | Chemical | denotes | heparan sulfate | MESH:D006497 |
| 247 | 751-753 | Chemical | denotes | HS | MESH:D006497 |
| 248 | 768-770 | Chemical | denotes | HP | MESH:D006493 |
| 249 | 809-812 | Chemical | denotes | GAG | MESH:D006025 |
| 250 | 855-865 | Chemical | denotes | hyaluronan | MESH:D006820 |
| 251 | 867-869 | Chemical | denotes | HA | MESH:D006820 |