PMC:7358770 / 37018-37632 JSONTXT

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{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T553","span":{"begin":14,"end":29},"obj":"Chemical"},{"id":"T554","span":{"begin":60,"end":71},"obj":"Chemical"},{"id":"T555","span":{"begin":72,"end":87},"obj":"Chemical"},{"id":"T556","span":{"begin":92,"end":100},"obj":"Chemical"},{"id":"T557","span":{"begin":208,"end":218},"obj":"Chemical"},{"id":"T558","span":{"begin":316,"end":323},"obj":"Chemical"},{"id":"T559","span":{"begin":375,"end":390},"obj":"Chemical"},{"id":"T560","span":{"begin":407,"end":414},"obj":"Chemical"},{"id":"T561","span":{"begin":415,"end":421},"obj":"Chemical"},{"id":"T562","span":{"begin":448,"end":461},"obj":"Chemical"},{"id":"T563","span":{"begin":470,"end":481},"obj":"Chemical"},{"id":"T564","span":{"begin":548,"end":555},"obj":"Chemical"},{"id":"T565","span":{"begin":585,"end":600},"obj":"Chemical"}],"attributes":[{"id":"A553","pred":"chebi_id","subj":"T553","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A554","pred":"chebi_id","subj":"T554","obj":"http://purl.obolibrary.org/obo/CHEBI_3435"},{"id":"A555","pred":"chebi_id","subj":"T555","obj":"http://purl.obolibrary.org/obo/CHEBI_50699"},{"id":"A556","pred":"chebi_id","subj":"T556","obj":"http://purl.obolibrary.org/obo/CHEBI_5181"},{"id":"A557","pred":"chebi_id","subj":"T557","obj":"http://purl.obolibrary.org/obo/CHEBI_63247"},{"id":"A558","pred":"chebi_id","subj":"T558","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A559","pred":"chebi_id","subj":"T559","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A560","pred":"chebi_id","subj":"T560","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A561","pred":"chebi_id","subj":"T561","obj":"http://purl.obolibrary.org/obo/CHEBI_37409"},{"id":"A562","pred":"chebi_id","subj":"T562","obj":"http://purl.obolibrary.org/obo/CHEBI_50803"},{"id":"A563","pred":"chebi_id","subj":"T563","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A564","pred":"chebi_id","subj":"T564","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A565","pred":"chebi_id","subj":"T565","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"}],"text":"Additionally, polysaccharides or their derivatives, such as carrageenan oligosaccharide and fucoidan derived from marine algae with biodegradability, abundance, and non-toxicity, can be used as biocompatible reductants for green synthesis AuNPs [134,135]. Based on our previous works, we hypothesize that the S or N protein from coronavirus can be designed to be loaded onto polysaccharides capped AuNPs by protein corona formation for coronavirus nanoparticles vaccine application (Fig. 9 ).\nFig. 9 The proposed schematics illustrating the S or N protein from coronavirus loaded onto polysaccharides capped AuNPs."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T82","span":{"begin":229,"end":238},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T83","span":{"begin":422,"end":431},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"Additionally, polysaccharides or their derivatives, such as carrageenan oligosaccharide and fucoidan derived from marine algae with biodegradability, abundance, and non-toxicity, can be used as biocompatible reductants for green synthesis AuNPs [134,135]. Based on our previous works, we hypothesize that the S or N protein from coronavirus can be designed to be loaded onto polysaccharides capped AuNPs by protein corona formation for coronavirus nanoparticles vaccine application (Fig. 9 ).\nFig. 9 The proposed schematics illustrating the S or N protein from coronavirus loaded onto polysaccharides capped AuNPs."}

{"project":"2_test","denotations":[{"id":"32679328-31043709-48281358","span":{"begin":246,"end":249},"obj":"31043709"},{"id":"32679328-27267570-48281359","span":{"begin":250,"end":253},"obj":"27267570"},{"id":"T26626","span":{"begin":246,"end":249},"obj":"31043709"},{"id":"T38564","span":{"begin":250,"end":253},"obj":"27267570"}],"text":"Additionally, polysaccharides or their derivatives, such as carrageenan oligosaccharide and fucoidan derived from marine algae with biodegradability, abundance, and non-toxicity, can be used as biocompatible reductants for green synthesis AuNPs [134,135]. Based on our previous works, we hypothesize that the S or N protein from coronavirus can be designed to be loaded onto polysaccharides capped AuNPs by protein corona formation for coronavirus nanoparticles vaccine application (Fig. 9 ).\nFig. 9 The proposed schematics illustrating the S or N protein from coronavirus loaded onto polysaccharides capped AuNPs."}

{"project":"LitCovid-sentences","denotations":[{"id":"T229","span":{"begin":0,"end":255},"obj":"Sentence"},{"id":"T230","span":{"begin":256,"end":492},"obj":"Sentence"},{"id":"T231","span":{"begin":493,"end":614},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Additionally, polysaccharides or their derivatives, such as carrageenan oligosaccharide and fucoidan derived from marine algae with biodegradability, abundance, and non-toxicity, can be used as biocompatible reductants for green synthesis AuNPs [134,135]. Based on our previous works, we hypothesize that the S or N protein from coronavirus can be designed to be loaded onto polysaccharides capped AuNPs by protein corona formation for coronavirus nanoparticles vaccine application (Fig. 9 ).\nFig. 9 The proposed schematics illustrating the S or N protein from coronavirus loaded onto polysaccharides capped AuNPs."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T1028","span":{"begin":14,"end":29},"obj":"CHEBI:18154;CHEBI:18154"},{"id":"T1029","span":{"begin":60,"end":71},"obj":"CHEBI:3435;CHEBI:3435"},{"id":"T1030","span":{"begin":72,"end":87},"obj":"CHEBI:50699;CHEBI:50699"},{"id":"T1031","span":{"begin":92,"end":100},"obj":"CHEBI:5181;CHEBI:5181"},{"id":"T1032","span":{"begin":314,"end":323},"obj":"PG_4"},{"id":"T1033","span":{"begin":329,"end":340},"obj":"NCBITaxon:11118"},{"id":"T1034","span":{"begin":375,"end":390},"obj":"CHEBI:18154;CHEBI:18154"},{"id":"T1035","span":{"begin":436,"end":447},"obj":"NCBITaxon:11118"},{"id":"T1036","span":{"begin":546,"end":555},"obj":"PG_4"},{"id":"T1037","span":{"begin":561,"end":572},"obj":"NCBITaxon:11118"},{"id":"T1038","span":{"begin":585,"end":600},"obj":"CHEBI:18154;CHEBI:18154"},{"id":"T22289","span":{"begin":190,"end":199},"obj":"PG_4"},{"id":"T87816","span":{"begin":205,"end":216},"obj":"NCBITaxon:11118"},{"id":"T59261","span":{"begin":251,"end":266},"obj":"CHEBI:18154;CHEBI:18154"},{"id":"T42889","span":{"begin":312,"end":323},"obj":"NCBITaxon:11118"},{"id":"T71749","span":{"begin":420,"end":429},"obj":"PG_4"},{"id":"T19010","span":{"begin":435,"end":446},"obj":"NCBITaxon:11118"},{"id":"T37619","span":{"begin":459,"end":474},"obj":"CHEBI:18154;CHEBI:18154"},{"id":"T1039","span":{"begin":548,"end":557},"obj":"PG_4"},{"id":"T1040","span":{"begin":563,"end":574},"obj":"NCBITaxon:11118"},{"id":"T1041","span":{"begin":587,"end":602},"obj":"CHEBI:18154;CHEBI:18154"}],"text":"Additionally, polysaccharides or their derivatives, such as carrageenan oligosaccharide and fucoidan derived from marine algae with biodegradability, abundance, and non-toxicity, can be used as biocompatible reductants for green synthesis AuNPs [134,135]. Based on our previous works, we hypothesize that the S or N protein from coronavirus can be designed to be loaded onto polysaccharides capped AuNPs by protein corona formation for coronavirus nanoparticles vaccine application (Fig. 9 ).\nFig. 9 The proposed schematics illustrating the S or N protein from coronavirus loaded onto polysaccharides capped AuNPs."}

{"project":"MyTest","denotations":[{"id":"1188","span":{"begin":561,"end":572},"obj":"Species"},{"id":"1189","span":{"begin":585,"end":600},"obj":"Chemical"},{"id":"1198","span":{"begin":121,"end":126},"obj":"Species"},{"id":"1199","span":{"begin":329,"end":340},"obj":"Species"},{"id":"1200","span":{"begin":436,"end":447},"obj":"Species"},{"id":"1201","span":{"begin":14,"end":29},"obj":"Chemical"},{"id":"1202","span":{"begin":60,"end":87},"obj":"Chemical"},{"id":"1203","span":{"begin":92,"end":100},"obj":"Chemical"},{"id":"1204","span":{"begin":375,"end":390},"obj":"Chemical"},{"id":"1205","span":{"begin":169,"end":177},"obj":"Disease"}],"attributes":[{"id":"A1198","pred":"tao:has_database_id","subj":"1198","obj":"Tax:569578"},{"id":"A1189","pred":"tao:has_database_id","subj":"1189","obj":"MESH:D011134"},{"id":"A1203","pred":"tao:has_database_id","subj":"1203","obj":"MESH:C007789"},{"id":"A1188","pred":"tao:has_database_id","subj":"1188","obj":"Tax:11118"},{"id":"A1204","pred":"tao:has_database_id","subj":"1204","obj":"MESH:D011134"},{"id":"A1205","pred":"tao:has_database_id","subj":"1205","obj":"MESH:D064420"},{"id":"A1201","pred":"tao:has_database_id","subj":"1201","obj":"MESH:D011134"},{"id":"A1199","pred":"tao:has_database_id","subj":"1199","obj":"Tax:11118"},{"id":"A1200","pred":"tao:has_database_id","subj":"1200","obj":"Tax:11118"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Additionally, polysaccharides or their derivatives, such as carrageenan oligosaccharide and fucoidan derived from marine algae with biodegradability, abundance, and non-toxicity, can be used as biocompatible reductants for green synthesis AuNPs [134,135]. Based on our previous works, we hypothesize that the S or N protein from coronavirus can be designed to be loaded onto polysaccharides capped AuNPs by protein corona formation for coronavirus nanoparticles vaccine application (Fig. 9 ).\nFig. 9 The proposed schematics illustrating the S or N protein from coronavirus loaded onto polysaccharides capped AuNPs."}