PMC:7358770 / 33753-35623
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T327 | 977-985 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T328 | 1009-1013 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T329 | 1306-1318 | Body_part | denotes | eosinophilic | http://purl.org/sig/ont/fma/fma62861 |
| T330 | 1509-1516 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T331 | 1585-1588 | Body_part | denotes | IgA | http://purl.org/sig/ont/fma/fma62874 |
| T332 | 1593-1596 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T333 | 1671-1674 | Body_part | denotes | IgM | http://purl.org/sig/ont/fma/fma62873 |
| T334 | 1686-1691 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T335 | 1745-1752 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T22 | 621-626 | Body_part | denotes | venom | http://purl.obolibrary.org/obo/UBERON_0007113 |
| T23 | 1686-1691 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1148 | 853-858 | Species | denotes | PRRSV | Tax:28344 |
| 1149 | 1027-1031 | Species | denotes | mice | Tax:10090 |
| 1150 | 1049-1057 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1151 | 1098-1106 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1152 | 1129-1134 | Species | denotes | mouse | Tax:10090 |
| 1153 | 1163-1167 | Species | denotes | mice | Tax:10090 |
| 1154 | 1207-1215 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1155 | 1266-1274 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1156 | 1453-1464 | Species | denotes | coronavirus | Tax:11118 |
| 1157 | 1482-1506 | Species | denotes | Bovine coronavirus (BCV) | Tax:11128 |
| 1158 | 1739-1742 | Species | denotes | BCV | Tax:11128 |
| 1159 | 98-117 | Disease | denotes | infectious diseases | MESH:D003141 |
| 1160 | 229-237 | Disease | denotes | toxicity | MESH:D064420 |
| 1161 | 859-868 | Disease | denotes | infection | MESH:D007239 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T143 | 98-108 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T144 | 628-630 | Disease | denotes | BV | http://purl.obolibrary.org/obo/MONDO_0005316 |
| T145 | 859-868 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T374 | 27-28 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T375 | 126-133 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T376 | 213-221 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T377 | 688-691 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T378 | 834-844 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T379 | 897-898 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T380 | 1007-1013 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
| T381 | 1047-1048 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T382 | 1096-1097 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T383 | 1129-1134 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T384 | 1244-1245 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T385 | 1819-1820 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T386 | 1858-1863 | http://purl.obolibrary.org/obo/UBERON_0007688 | denotes | field |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T506 | 275-286 | Chemical | denotes | application | http://purl.obolibrary.org/obo/CHEBI_33232 |
| T507 | 290-303 | Chemical | denotes | nanoparticles | http://purl.obolibrary.org/obo/CHEBI_50803 |
| T508 | 385-392 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T509 | 529-538 | Chemical | denotes | adjuvants | http://purl.obolibrary.org/obo/CHEBI_60809 |
| T510 | 573-581 | Chemical | denotes | chitosan | http://purl.obolibrary.org/obo/CHEBI_16261|http://purl.obolibrary.org/obo/CHEBI_57704 |
| T512 | 582-590 | Chemical | denotes | alginate | http://purl.obolibrary.org/obo/CHEBI_58187 |
| T513 | 591-603 | Chemical | denotes | nanoparticle | http://purl.obolibrary.org/obo/CHEBI_50803 |
| T514 | 621-626 | Chemical | denotes | venom | http://purl.obolibrary.org/obo/CHEBI_78505 |
| T515 | 905-917 | Chemical | denotes | nanoparticle | http://purl.obolibrary.org/obo/CHEBI_50803 |
| T516 | 990-997 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T517 | 1058-1070 | Chemical | denotes | nanoparticle | http://purl.obolibrary.org/obo/CHEBI_50803 |
| T518 | 1188-1200 | Chemical | denotes | nanoparticle | http://purl.obolibrary.org/obo/CHEBI_50803 |
| T519 | 1361-1373 | Chemical | denotes | nanoparticle | http://purl.obolibrary.org/obo/CHEBI_50803 |
| T520 | 1509-1516 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T521 | 1524-1532 | Chemical | denotes | chitosan | http://purl.obolibrary.org/obo/CHEBI_16261|http://purl.obolibrary.org/obo/CHEBI_57704 |
| T523 | 1533-1546 | Chemical | denotes | nanoparticles | http://purl.obolibrary.org/obo/CHEBI_50803 |
| T524 | 1548-1551 | Chemical | denotes | CNP | http://purl.obolibrary.org/obo/CHEBI_80235 |
| T525 | 1660-1665 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T526 | 1745-1752 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T527 | 1760-1763 | Chemical | denotes | CNP | http://purl.obolibrary.org/obo/CHEBI_80235 |
| T528 | 1764-1769 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T529 | 1800-1803 | Chemical | denotes | CNP | http://purl.obolibrary.org/obo/CHEBI_80235 |
| T530 | 1827-1835 | Chemical | denotes | adjuvant | http://purl.obolibrary.org/obo/CHEBI_60809 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32679328-31647394-48281347 | 452-455 | 31647394 | denotes | 126 |
| 32679328-26154342-48281348 | 563-566 | 26154342 | denotes | 127 |
| 32679328-29776611-48281349 | 870-873 | 29776611 | denotes | 128 |
| T91461 | 452-455 | 31647394 | denotes | 126 |
| T4724 | 563-566 | 26154342 | denotes | 127 |
| T23491 | 870-873 | 29776611 | denotes | 128 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T209 | 0-134 | Sentence | denotes | Nanobiotechnology provides a variety of solutions for the prevention, diagnosis, and treatment of infectious diseases such as viruses. |
| T210 | 135-270 | Sentence | denotes | Nanoparticles can be designed as an efficient delivery system to increase the activity of low toxicity vaccines against the host [125]. |
| T211 | 271-457 | Sentence | denotes | The application of nanoparticles in vaccine formulations can not only improve the immunogenicity and stability of antigen, but also achieve targeted delivery and sustained release [126]. |
| T212 | 458-568 | Sentence | denotes | Nanomaterials may have intrinsic immunomodulatory functions, acting as adjuvants or immune potentiators [127]. |
| T213 | 569-875 | Sentence | denotes | The chitosan/alginate nanoparticle encapsulated bee venom (BV) with slow-releasing properties and mucosal adhesiveness has been developed, which can effectively induce non-specific immune stimulation, particularly those related to Th1 responses and viral clearance activities against PRRSV infection [128]. |
| T214 | 876-1089 | Sentence | denotes | The effectiveness of a novel nanoparticle vaccine is supported by stimulating effective neutralizing antibody and antigen-specific T cell responses in mice immunized with a MERS-CoV nanoparticle vaccine candidate. |
| T215 | 1090-1335 | Sentence | denotes | Using a MERS-CoV-permissive transgenic mouse model, it is shown that the mice immunized with this nanoparticle-based MERS-CoV vaccine can protect against a lethal challenge of MERS-CoV without triggering undesirable eosinophilic immunopathology. |
| T216 | 1336-1481 | Sentence | denotes | The biocompatible hollow nanoparticle may accelerate the development of effective and safe vaccines against emerging coronavirus pathogens [129]. |
| T217 | 1482-1666 | Sentence | denotes | Bovine coronavirus (BCV) N protein-loaded chitosan nanoparticles (CNP) can significantly increase both IgA and IgG levels after the second immunization comparable to the control group. |
| T218 | 1667-1770 | Sentence | denotes | The IgM content in serum increased after the second immunization in the BCV N protein-loaded CNP group. |
| T219 | 1771-1870 | Sentence | denotes | These findings indicate that CNP can be used as a novel adjuvant in veterinary vaccine field [130]. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T963 | 40-49 | CHEBI:75958;CHEBI:75958 | denotes | solutions |
| T964 | 126-133 | NCBITaxon:10239 | denotes | viruses |
| T965 | 290-303 | GO:0031982 | denotes | nanoparticles |
| T966 | 353-367 | BV_15 | denotes | immunogenicity |
| T967 | 385-392 | CHEBI:59132;CHEBI:59132 | denotes | antigen |
| T968 | 529-538 | CHEBI:60809;CHEBI:60809 | denotes | adjuvants |
| T969 | 542-548 | UBERON:0002405 | denotes | immune |
| T970 | 573-581 | CHEBI:16261;CHEBI:16261 | denotes | chitosan |
| T971 | 617-620 | NCBITaxon:7460 | denotes | bee |
| T972 | 667-674 | UBERON:0000912 | denotes | mucosal |
| T973 | 750-756 | UBERON:0002405 | denotes | immune |
| T974 | 800-813 | GO:0042110 | denotes | Th1 responses |
| T975 | 818-823 | NCBITaxon:10239 | denotes | viral |
| T976 | 853-858 | NCBITaxon:42413 | denotes | PRRSV |
| T977 | 977-985 | GO:0042571 | denotes | antibody |
| T978 | 990-997 | CHEBI:59132;CHEBI:59132 | denotes | antigen |
| T979 | 1007-1008 | CL:0000084 | denotes | T |
| T980 | 1009-1013 | CL:0000084;GO:0042110 | denotes | cell |
| T981 | 1027-1031 | NCBITaxon:10088 | denotes | mice |
| T982 | 1049-1057 | SP_9 | denotes | MERS-CoV |
| T983 | 1098-1106 | SP_9 | denotes | MERS-CoV |
| T984 | 1129-1134 | NCBITaxon:10088 | denotes | mouse |
| T985 | 1163-1167 | NCBITaxon:10088 | denotes | mice |
| T986 | 1188-1200 | CHEBI:50803;CHEBI:50803 | denotes | nanoparticle |
| T987 | 1207-1215 | SP_9 | denotes | MERS-CoV |
| T988 | 1266-1274 | SP_9 | denotes | MERS-CoV |
| T989 | 1306-1318 | CL:0000771 | denotes | eosinophilic |
| T990 | 1453-1464 | NCBITaxon:11118 | denotes | coronavirus |
| T991 | 1482-1488 | NCBITaxon:27592 | denotes | Bovine |
| T992 | 1489-1500 | NCBITaxon:11118 | denotes | coronavirus |
| T993 | 1507-1516 | PG_4 | denotes | N protein |
| T994 | 1524-1532 | CHEBI:16261;CHEBI:16261 | denotes | chitosan |
| T995 | 1585-1588 | GO:0071735 | denotes | IgA |
| T996 | 1593-1596 | GO:0071735 | denotes | IgG |
| T997 | 1671-1674 | GO:0071735 | denotes | IgM |
| T998 | 1686-1691 | UBERON:0001977 | denotes | serum |
| T999 | 1743-1752 | PG_4 | denotes | N protein |
| T1000 | 1827-1835 | CHEBI:60809;CHEBI:60809 | denotes | adjuvant |
| T50281 | 9-22 | GO:0031982 | denotes | chnology prov |
| T79323 | 71-84 | BV_15 | denotes | iagnosis, and |
| T87731 | 102-109 | CHEBI:59132;CHEBI:59132 | denotes | ctious |
| T93585 | 244-253 | CHEBI:60809;CHEBI:60809 | denotes | es agains |
| T74571 | 257-262 | UBERON:0002405 | denotes | e hos |
| T83905 | 287-293 | CHEBI:16261;CHEBI:16261 | denotes | of nan |
| T60667 | 330-333 | NCBITaxon:7460 | denotes | n n |
| T82055 | 381-387 | UBERON:0000912 | denotes | of an |
| T34262 | 465-470 | UBERON:0002405 | denotes | erial |
| T56816 | 514-527 | GO:0042110 | denotes | ons, acting a |
| T10408 | 532-537 | NCBITaxon:10239 | denotes | uvant |
| T21597 | 568-573 | NCBITaxon:42413 | denotes | The |
| T89685 | 694-702 | GO:0042571 | denotes | en devel |
| T54248 | 707-714 | CHEBI:59132;CHEBI:59132 | denotes | which |
| T75414 | 724-725 | CL:0000084 | denotes | i |
| T38436 | 726-730 | CL:0000084;GO:0042110 | denotes | ely |
| T88531 | 744-748 | NCBITaxon:10088 | denotes | cifi |
| T10095 | 767-775 | SP_9 | denotes | n, parti |
| T43562 | 816-824 | SP_9 | denotes | d viral |
| T4048 | 847-852 | NCBITaxon:10088 | denotes | ainst |
| T43378 | 881-885 | NCBITaxon:10088 | denotes | ffec |
| T54097 | 905-917 | CHEBI:50803;CHEBI:50803 | denotes | nanoparticle |
| T48256 | 924-932 | SP_9 | denotes | e is sup |
| T69198 | 984-992 | SP_9 | denotes | y and an |
| T80961 | 1024-1034 | CL:0000771 | denotes | in mice im |
| T73673 | 1169-1181 | NCBITaxon:11118 | denotes | mmunized wit |
| T13292 | 1199-1205 | NCBITaxon:27592 | denotes | e-base |
| T10371 | 1206-1217 | NCBITaxon:11118 | denotes | MERS-CoV v |
| T92482 | 1224-1233 | PG_4 | denotes | can prote |
| T60172 | 1241-1247 | CHEBI:16261;CHEBI:16261 | denotes | st a l |
| T68568 | 1300-1303 | GO:0071735 | denotes | rab |
| T86288 | 1308-1311 | GO:0071735 | denotes | sin |
| T7719 | 1388-1391 | GO:0071735 | denotes | th |
| T41043 | 1403-1408 | UBERON:0001977 | denotes | t of |
| T91616 | 1459-1468 | PG_4 | denotes | virus pat |
| T37714 | 1545-1553 | CHEBI:60809;CHEBI:60809 | denotes | s (CNP) |
| T30064 | 1705-1716 | NCBITaxon:11118 | denotes | er the seco |
| T35628 | 1838-1846 | SP_9 | denotes | veterin |
MyTest
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1148 | 853-858 | Species | denotes | PRRSV | Tax:28344 |
| 1149 | 1027-1031 | Species | denotes | mice | Tax:10090 |
| 1150 | 1049-1057 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1151 | 1098-1106 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1152 | 1129-1134 | Species | denotes | mouse | Tax:10090 |
| 1153 | 1163-1167 | Species | denotes | mice | Tax:10090 |
| 1154 | 1207-1215 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1155 | 1266-1274 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1156 | 1453-1464 | Species | denotes | coronavirus | Tax:11118 |
| 1157 | 1482-1506 | Species | denotes | Bovine coronavirus (BCV) | Tax:11128 |
| 1158 | 1739-1742 | Species | denotes | BCV | Tax:11128 |
| 1159 | 98-117 | Disease | denotes | infectious diseases | MESH:D003141 |
| 1160 | 229-237 | Disease | denotes | toxicity | MESH:D064420 |
| 1161 | 859-868 | Disease | denotes | infection | MESH:D007239 |