PMC:7352545 / 88587-89092
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T859","span":{"begin":13,"end":30},"obj":"Body_part"},{"id":"T860","span":{"begin":32,"end":35},"obj":"Body_part"},{"id":"T861","span":{"begin":91,"end":97},"obj":"Body_part"},{"id":"T862","span":{"begin":102,"end":104},"obj":"Body_part"},{"id":"T863","span":{"begin":110,"end":112},"obj":"Body_part"},{"id":"T864","span":{"begin":141,"end":146},"obj":"Body_part"},{"id":"T865","span":{"begin":191,"end":193},"obj":"Body_part"},{"id":"T866","span":{"begin":202,"end":207},"obj":"Body_part"},{"id":"T867","span":{"begin":242,"end":245},"obj":"Body_part"},{"id":"T868","span":{"begin":364,"end":379},"obj":"Body_part"},{"id":"T869","span":{"begin":395,"end":410},"obj":"Body_part"},{"id":"T870","span":{"begin":412,"end":416},"obj":"Body_part"}],"attributes":[{"id":"A859","pred":"fma_id","subj":"T859","obj":"http://purl.org/sig/ont/fma/fma63011"},{"id":"A860","pred":"fma_id","subj":"T860","obj":"http://purl.org/sig/ont/fma/fma63011"},{"id":"A861","pred":"fma_id","subj":"T861","obj":"http://purl.org/sig/ont/fma/fma82764"},{"id":"A862","pred":"fma_id","subj":"T862","obj":"http://purl.org/sig/ont/fma/fma63023"},{"id":"A863","pred":"fma_id","subj":"T863","obj":"http://purl.org/sig/ont/fma/fma63023"},{"id":"A864","pred":"fma_id","subj":"T864","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A865","pred":"fma_id","subj":"T865","obj":"http://purl.org/sig/ont/fma/fma63023"},{"id":"A866","pred":"fma_id","subj":"T866","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A867","pred":"fma_id","subj":"T867","obj":"http://purl.org/sig/ont/fma/fma63011"},{"id":"A868","pred":"fma_id","subj":"T868","obj":"http://purl.org/sig/ont/fma/fma63023"},{"id":"A869","pred":"fma_id","subj":"T869","obj":"http://purl.org/sig/ont/fma/fma82798"},{"id":"A870","pred":"fma_id","subj":"T870","obj":"http://purl.org/sig/ont/fma/fma82798"}],"text":"Structure of glycosaminoglycan (GAG)-linkage tetrasaccharide, GluAβ1,3Galβ1,3Galβ1,4Xylβ-O-serine and HS; (A) HS structure; (B) Sulfation of sugar residues; (C) Synthesis and localization of HS in host cells. Glycosyltransferases involved in GAG synthesis include (i) GlcAT-II (glucuronosyltransferase) and (ii) GlcNAcT-II (N-acetylglucosaminyltransferase II) for heparan sulfate synthesis. β-D-glucuronic acid (GlcA), α-L-iduronic acid (IdoA) and 2-O-sulfo-α-L-iduronic acid (IdoA(2S) are composed [124]."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"4053","span":{"begin":13,"end":30},"obj":"Chemical"},{"id":"4054","span":{"begin":32,"end":35},"obj":"Chemical"},{"id":"4055","span":{"begin":45,"end":60},"obj":"Chemical"},{"id":"4056","span":{"begin":91,"end":97},"obj":"Chemical"},{"id":"4057","span":{"begin":102,"end":104},"obj":"Chemical"},{"id":"4058","span":{"begin":110,"end":112},"obj":"Chemical"},{"id":"4059","span":{"begin":242,"end":245},"obj":"Chemical"},{"id":"4060","span":{"begin":268,"end":276},"obj":"Chemical"},{"id":"4061","span":{"begin":364,"end":379},"obj":"Chemical"},{"id":"4062","span":{"begin":391,"end":410},"obj":"Chemical"},{"id":"4063","span":{"begin":412,"end":416},"obj":"Chemical"},{"id":"4064","span":{"begin":419,"end":436},"obj":"Chemical"},{"id":"4065","span":{"begin":438,"end":442},"obj":"Chemical"},{"id":"4066","span":{"begin":448,"end":475},"obj":"Chemical"},{"id":"4067","span":{"begin":477,"end":481},"obj":"Chemical"}],"attributes":[{"id":"A4053","pred":"tao:has_database_id","subj":"4053","obj":"MESH:D006025"},{"id":"A4054","pred":"tao:has_database_id","subj":"4054","obj":"MESH:D006025"},{"id":"A4056","pred":"tao:has_database_id","subj":"4056","obj":"MESH:D012694"},{"id":"A4057","pred":"tao:has_database_id","subj":"4057","obj":"MESH:D006497"},{"id":"A4058","pred":"tao:has_database_id","subj":"4058","obj":"MESH:D006497"},{"id":"A4059","pred":"tao:has_database_id","subj":"4059","obj":"MESH:D006025"},{"id":"A4061","pred":"tao:has_database_id","subj":"4061","obj":"MESH:D006497"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Structure of glycosaminoglycan (GAG)-linkage tetrasaccharide, GluAβ1,3Galβ1,3Galβ1,4Xylβ-O-serine and HS; (A) HS structure; (B) Sulfation of sugar residues; (C) Synthesis and localization of HS in host cells. Glycosyltransferases involved in GAG synthesis include (i) GlcAT-II (glucuronosyltransferase) and (ii) GlcNAcT-II (N-acetylglucosaminyltransferase II) for heparan sulfate synthesis. β-D-glucuronic acid (GlcA), α-L-iduronic acid (IdoA) and 2-O-sulfo-α-L-iduronic acid (IdoA(2S) are composed [124]."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1186","span":{"begin":102,"end":109},"obj":"http://purl.obolibrary.org/obo/PR_000001932"},{"id":"T1187","span":{"begin":125,"end":126},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T1188","span":{"begin":202,"end":207},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Structure of glycosaminoglycan (GAG)-linkage tetrasaccharide, GluAβ1,3Galβ1,3Galβ1,4Xylβ-O-serine and HS; (A) HS structure; (B) Sulfation of sugar residues; (C) Synthesis and localization of HS in host cells. Glycosyltransferases involved in GAG synthesis include (i) GlcAT-II (glucuronosyltransferase) and (ii) GlcNAcT-II (N-acetylglucosaminyltransferase II) for heparan sulfate synthesis. β-D-glucuronic acid (GlcA), α-L-iduronic acid (IdoA) and 2-O-sulfo-α-L-iduronic acid (IdoA(2S) are composed [124]."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T56175","span":{"begin":13,"end":30},"obj":"Chemical"},{"id":"T77968","span":{"begin":32,"end":35},"obj":"Chemical"},{"id":"T916","span":{"begin":45,"end":60},"obj":"Chemical"},{"id":"T917","span":{"begin":70,"end":73},"obj":"Chemical"},{"id":"T918","span":{"begin":77,"end":80},"obj":"Chemical"},{"id":"T46997","span":{"begin":84,"end":87},"obj":"Chemical"},{"id":"T920","span":{"begin":91,"end":97},"obj":"Chemical"},{"id":"T921","span":{"begin":102,"end":104},"obj":"Chemical"},{"id":"T922","span":{"begin":110,"end":112},"obj":"Chemical"},{"id":"T923","span":{"begin":191,"end":193},"obj":"Chemical"},{"id":"T31866","span":{"begin":242,"end":245},"obj":"Chemical"},{"id":"T37633","span":{"begin":274,"end":276},"obj":"Chemical"},{"id":"T927","span":{"begin":320,"end":322},"obj":"Chemical"},{"id":"T84729","span":{"begin":356,"end":358},"obj":"Chemical"},{"id":"T929","span":{"begin":364,"end":379},"obj":"Chemical"},{"id":"T12333","span":{"begin":364,"end":371},"obj":"Chemical"},{"id":"T931","span":{"begin":372,"end":379},"obj":"Chemical"},{"id":"T932","span":{"begin":393,"end":410},"obj":"Chemical"},{"id":"T57649","span":{"begin":395,"end":410},"obj":"Chemical"},{"id":"T936","span":{"begin":406,"end":410},"obj":"Chemical"},{"id":"T937","span":{"begin":412,"end":416},"obj":"Chemical"},{"id":"T938","span":{"begin":421,"end":436},"obj":"Chemical"},{"id":"T55375","span":{"begin":423,"end":436},"obj":"Chemical"},{"id":"T15629","span":{"begin":432,"end":436},"obj":"Chemical"},{"id":"T942","span":{"begin":438,"end":442},"obj":"Chemical"},{"id":"T34978","span":{"begin":452,"end":457},"obj":"Chemical"},{"id":"T944","span":{"begin":460,"end":475},"obj":"Chemical"},{"id":"T946","span":{"begin":462,"end":475},"obj":"Chemical"},{"id":"T947","span":{"begin":471,"end":475},"obj":"Chemical"},{"id":"T66810","span":{"begin":477,"end":481},"obj":"Chemical"}],"attributes":[{"id":"A32859","pred":"chebi_id","subj":"T56175","obj":"http://purl.obolibrary.org/obo/CHEBI_18085"},{"id":"A55891","pred":"chebi_id","subj":"T77968","obj":"http://purl.obolibrary.org/obo/CHEBI_143889"},{"id":"A45185","pred":"chebi_id","subj":"T77968","obj":"http://purl.obolibrary.org/obo/CHEBI_18085"},{"id":"A17835","pred":"chebi_id","subj":"T916","obj":"http://purl.obolibrary.org/obo/CHEBI_50126"},{"id":"A69815","pred":"chebi_id","subj":"T917","obj":"http://purl.obolibrary.org/obo/CHEBI_28260"},{"id":"A46495","pred":"chebi_id","subj":"T918","obj":"http://purl.obolibrary.org/obo/CHEBI_28260"},{"id":"A98124","pred":"chebi_id","subj":"T46997","obj":"http://purl.obolibrary.org/obo/CHEBI_18222"},{"id":"A57802","pred":"chebi_id","subj":"T920","obj":"http://purl.obolibrary.org/obo/CHEBI_17822"},{"id":"A7097","pred":"chebi_id","subj":"T921","obj":"http://purl.obolibrary.org/obo/CHEBI_74056"},{"id":"A25447","pred":"chebi_id","subj":"T922","obj":"http://purl.obolibrary.org/obo/CHEBI_74056"},{"id":"A36243","pred":"chebi_id","subj":"T923","obj":"http://purl.obolibrary.org/obo/CHEBI_74056"},{"id":"A10045","pred":"chebi_id","subj":"T31866","obj":"http://purl.obolibrary.org/obo/CHEBI_143889"},{"id":"A75656","pred":"chebi_id","subj":"T31866","obj":"http://purl.obolibrary.org/obo/CHEBI_18085"},{"id":"A82327","pred":"chebi_id","subj":"T37633","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A86905","pred":"chebi_id","subj":"T927","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A96805","pred":"chebi_id","subj":"T84729","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A75304","pred":"chebi_id","subj":"T929","obj":"http://purl.obolibrary.org/obo/CHEBI_28815"},{"id":"A46845","pred":"chebi_id","subj":"T12333","obj":"http://purl.obolibrary.org/obo/CHEBI_24500"},{"id":"A87588","pred":"chebi_id","subj":"T931","obj":"http://purl.obolibrary.org/obo/CHEBI_16189"},{"id":"A83323","pred":"chebi_id","subj":"T932","obj":"http://purl.obolibrary.org/obo/CHEBI_4178"},{"id":"A21212","pred":"chebi_id","subj":"T932","obj":"http://purl.obolibrary.org/obo/CHEBI_47952"},{"id":"A18753","pred":"chebi_id","subj":"T932","obj":"http://purl.obolibrary.org/obo/CHEBI_47953"},{"id":"A71555","pred":"chebi_id","subj":"T57649","obj":"http://purl.obolibrary.org/obo/CHEBI_24298"},{"id":"A3972","pred":"chebi_id","subj":"T936","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A12638","pred":"chebi_id","subj":"T937","obj":"http://purl.obolibrary.org/obo/CHEBI_24298"},{"id":"A29711","pred":"chebi_id","subj":"T938","obj":"http://purl.obolibrary.org/obo/CHEBI_28481"},{"id":"A69335","pred":"chebi_id","subj":"T938","obj":"http://purl.obolibrary.org/obo/CHEBI_85187"},{"id":"A16009","pred":"chebi_id","subj":"T55375","obj":"http://purl.obolibrary.org/obo/CHEBI_24769"},{"id":"A18328","pred":"chebi_id","subj":"T15629","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A67041","pred":"chebi_id","subj":"T942","obj":"http://purl.obolibrary.org/obo/CHEBI_24769"},{"id":"A83922","pred":"chebi_id","subj":"T34978","obj":"http://purl.obolibrary.org/obo/CHEBI_29922"},{"id":"A12771","pred":"chebi_id","subj":"T944","obj":"http://purl.obolibrary.org/obo/CHEBI_28481"},{"id":"A14645","pred":"chebi_id","subj":"T944","obj":"http://purl.obolibrary.org/obo/CHEBI_85187"},{"id":"A51295","pred":"chebi_id","subj":"T946","obj":"http://purl.obolibrary.org/obo/CHEBI_24769"},{"id":"A62794","pred":"chebi_id","subj":"T947","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A59616","pred":"chebi_id","subj":"T66810","obj":"http://purl.obolibrary.org/obo/CHEBI_24769"}],"text":"Structure of glycosaminoglycan (GAG)-linkage tetrasaccharide, GluAβ1,3Galβ1,3Galβ1,4Xylβ-O-serine and HS; (A) HS structure; (B) Sulfation of sugar residues; (C) Synthesis and localization of HS in host cells. Glycosyltransferases involved in GAG synthesis include (i) GlcAT-II (glucuronosyltransferase) and (ii) GlcNAcT-II (N-acetylglucosaminyltransferase II) for heparan sulfate synthesis. β-D-glucuronic acid (GlcA), α-L-iduronic acid (IdoA) and 2-O-sulfo-α-L-iduronic acid (IdoA(2S) are composed [124]."}
LitCovid-PD-GO-BP
{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T162","span":{"begin":128,"end":137},"obj":"http://purl.obolibrary.org/obo/GO_0051923"},{"id":"T163","span":{"begin":161,"end":170},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T164","span":{"begin":175,"end":187},"obj":"http://purl.obolibrary.org/obo/GO_0051179"},{"id":"T165","span":{"begin":246,"end":255},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T166","span":{"begin":380,"end":389},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T167","span":{"begin":412,"end":416},"obj":"http://purl.obolibrary.org/obo/GO_0043879"}],"text":"Structure of glycosaminoglycan (GAG)-linkage tetrasaccharide, GluAβ1,3Galβ1,3Galβ1,4Xylβ-O-serine and HS; (A) HS structure; (B) Sulfation of sugar residues; (C) Synthesis and localization of HS in host cells. Glycosyltransferases involved in GAG synthesis include (i) GlcAT-II (glucuronosyltransferase) and (ii) GlcNAcT-II (N-acetylglucosaminyltransferase II) for heparan sulfate synthesis. β-D-glucuronic acid (GlcA), α-L-iduronic acid (IdoA) and 2-O-sulfo-α-L-iduronic acid (IdoA(2S) are composed [124]."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T929","span":{"begin":209,"end":505},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Structure of glycosaminoglycan (GAG)-linkage tetrasaccharide, GluAβ1,3Galβ1,3Galβ1,4Xylβ-O-serine and HS; (A) HS structure; (B) Sulfation of sugar residues; (C) Synthesis and localization of HS in host cells. Glycosyltransferases involved in GAG synthesis include (i) GlcAT-II (glucuronosyltransferase) and (ii) GlcNAcT-II (N-acetylglucosaminyltransferase II) for heparan sulfate synthesis. β-D-glucuronic acid (GlcA), α-L-iduronic acid (IdoA) and 2-O-sulfo-α-L-iduronic acid (IdoA(2S) are composed [124]."}
LitCovid-PD-GlycoEpitope
{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T29","span":{"begin":102,"end":104},"obj":"GlycoEpitope"},{"id":"T30","span":{"begin":110,"end":112},"obj":"GlycoEpitope"},{"id":"T31","span":{"begin":191,"end":193},"obj":"GlycoEpitope"},{"id":"T32","span":{"begin":364,"end":379},"obj":"GlycoEpitope"}],"attributes":[{"id":"A29","pred":"glyco_epitope_db_id","subj":"T29","obj":"http://www.glycoepitope.jp/epitopes/EP0086"},{"id":"A30","pred":"glyco_epitope_db_id","subj":"T30","obj":"http://www.glycoepitope.jp/epitopes/EP0086"},{"id":"A31","pred":"glyco_epitope_db_id","subj":"T31","obj":"http://www.glycoepitope.jp/epitopes/EP0086"},{"id":"A32","pred":"glyco_epitope_db_id","subj":"T32","obj":"http://www.glycoepitope.jp/epitopes/EP0086"}],"text":"Structure of glycosaminoglycan (GAG)-linkage tetrasaccharide, GluAβ1,3Galβ1,3Galβ1,4Xylβ-O-serine and HS; (A) HS structure; (B) Sulfation of sugar residues; (C) Synthesis and localization of HS in host cells. Glycosyltransferases involved in GAG synthesis include (i) GlcAT-II (glucuronosyltransferase) and (ii) GlcNAcT-II (N-acetylglucosaminyltransferase II) for heparan sulfate synthesis. β-D-glucuronic acid (GlcA), α-L-iduronic acid (IdoA) and 2-O-sulfo-α-L-iduronic acid (IdoA(2S) are composed [124]."}