
PMC:7352545 / 8592-10616
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T48","span":{"begin":500,"end":504},"obj":"Body_part"},{"id":"T49","span":{"begin":1256,"end":1259},"obj":"Body_part"},{"id":"T50","span":{"begin":1314,"end":1317},"obj":"Body_part"},{"id":"T51","span":{"begin":1349,"end":1355},"obj":"Body_part"},{"id":"T52","span":{"begin":1384,"end":1387},"obj":"Body_part"},{"id":"T53","span":{"begin":1389,"end":1399},"obj":"Body_part"},{"id":"T54","span":{"begin":1423,"end":1430},"obj":"Body_part"},{"id":"T55","span":{"begin":1509,"end":1519},"obj":"Body_part"},{"id":"T56","span":{"begin":1759,"end":1777},"obj":"Body_part"},{"id":"T57","span":{"begin":1892,"end":1898},"obj":"Body_part"},{"id":"T58","span":{"begin":1971,"end":1974},"obj":"Body_part"}],"attributes":[{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma82740"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma82740"},{"id":"A56","pred":"fma_id","subj":"T56","obj":"http://purl.org/sig/ont/fma/fma265130"},{"id":"A57","pred":"fma_id","subj":"T57","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
LitCovid-PD-UBERON
{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T2","span":{"begin":500,"end":504},"obj":"Body_part"},{"id":"T3","span":{"begin":1759,"end":1777},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"310","span":{"begin":26,"end":32},"obj":"Species"},{"id":"311","span":{"begin":55,"end":59},"obj":"Species"},{"id":"312","span":{"begin":167,"end":176},"obj":"Species"},{"id":"313","span":{"begin":274,"end":285},"obj":"Species"},{"id":"314","span":{"begin":302,"end":305},"obj":"Species"},{"id":"315","span":{"begin":328,"end":331},"obj":"Species"},{"id":"316","span":{"begin":333,"end":338},"obj":"Species"},{"id":"317","span":{"begin":342,"end":345},"obj":"Species"},{"id":"318","span":{"begin":352,"end":355},"obj":"Species"},{"id":"319","span":{"begin":361,"end":370},"obj":"Species"},{"id":"320","span":{"begin":374,"end":384},"obj":"Species"},{"id":"321","span":{"begin":399,"end":404},"obj":"Species"},{"id":"322","span":{"begin":438,"end":447},"obj":"Species"},{"id":"323","span":{"begin":494,"end":499},"obj":"Species"},{"id":"324","span":{"begin":512,"end":515},"obj":"Species"},{"id":"325","span":{"begin":520,"end":525},"obj":"Species"},{"id":"326","span":{"begin":539,"end":545},"obj":"Species"},{"id":"327","span":{"begin":564,"end":567},"obj":"Species"},{"id":"328","span":{"begin":574,"end":577},"obj":"Species"},{"id":"329","span":{"begin":623,"end":628},"obj":"Species"},{"id":"330","span":{"begin":695,"end":703},"obj":"Species"},{"id":"331","span":{"begin":708,"end":718},"obj":"Species"},{"id":"332","span":{"begin":739,"end":747},"obj":"Species"},{"id":"333","span":{"begin":763,"end":771},"obj":"Species"},{"id":"334","span":{"begin":786,"end":794},"obj":"Species"},{"id":"335","span":{"begin":822,"end":826},"obj":"Species"},{"id":"336","span":{"begin":867,"end":873},"obj":"Species"},{"id":"337","span":{"begin":419,"end":427},"obj":"Disease"},{"id":"338","span":{"begin":448,"end":457},"obj":"Disease"},{"id":"339","span":{"begin":467,"end":486},"obj":"Disease"},{"id":"379","span":{"begin":1553,"end":1556},"obj":"Gene"},{"id":"380","span":{"begin":889,"end":893},"obj":"Species"},{"id":"381","span":{"begin":897,"end":903},"obj":"Species"},{"id":"382","span":{"begin":1044,"end":1049},"obj":"Species"},{"id":"383","span":{"begin":1050,"end":1053},"obj":"Species"},{"id":"384","span":{"begin":1062,"end":1071},"obj":"Species"},{"id":"385","span":{"begin":1076,"end":1085},"obj":"Species"},{"id":"386","span":{"begin":1095,"end":1100},"obj":"Species"},{"id":"387","span":{"begin":1153,"end":1156},"obj":"Species"},{"id":"388","span":{"begin":1158,"end":1167},"obj":"Species"},{"id":"389","span":{"begin":1172,"end":1181},"obj":"Species"},{"id":"390","span":{"begin":1187,"end":1192},"obj":"Species"},{"id":"391","span":{"begin":1194,"end":1202},"obj":"Species"},{"id":"392","span":{"begin":1204,"end":1214},"obj":"Species"},{"id":"393","span":{"begin":1216,"end":1225},"obj":"Species"},{"id":"394","span":{"begin":1227,"end":1236},"obj":"Species"},{"id":"395","span":{"begin":1241,"end":1249},"obj":"Species"},{"id":"396","span":{"begin":1252,"end":1255},"obj":"Species"},{"id":"397","span":{"begin":1327,"end":1331},"obj":"Species"},{"id":"398","span":{"begin":1413,"end":1416},"obj":"Species"},{"id":"399","span":{"begin":1454,"end":1462},"obj":"Species"},{"id":"400","span":{"begin":1567,"end":1570},"obj":"Species"},{"id":"401","span":{"begin":1611,"end":1619},"obj":"Species"},{"id":"402","span":{"begin":1639,"end":1642},"obj":"Species"},{"id":"403","span":{"begin":1666,"end":1671},"obj":"Species"},{"id":"404","span":{"begin":1704,"end":1714},"obj":"Species"},{"id":"405","span":{"begin":1718,"end":1727},"obj":"Species"},{"id":"406","span":{"begin":1734,"end":1744},"obj":"Species"},{"id":"407","span":{"begin":1753,"end":1758},"obj":"Species"},{"id":"408","span":{"begin":1813,"end":1823},"obj":"Species"},{"id":"409","span":{"begin":1829,"end":1838},"obj":"Species"},{"id":"410","span":{"begin":1911,"end":1921},"obj":"Species"},{"id":"411","span":{"begin":1962,"end":1970},"obj":"Species"},{"id":"412","span":{"begin":2001,"end":2009},"obj":"Species"},{"id":"413","span":{"begin":1101,"end":1111},"obj":"Species"},{"id":"414","span":{"begin":1759,"end":1770},"obj":"Species"},{"id":"415","span":{"begin":924,"end":946},"obj":"Disease"},{"id":"416","span":{"begin":1445,"end":1453},"obj":"Disease"},{"id":"417","span":{"begin":1802,"end":1811},"obj":"Disease"}],"attributes":[{"id":"A310","pred":"tao:has_database_id","subj":"310","obj":"Tax:9606"},{"id":"A311","pred":"tao:has_database_id","subj":"311","obj":"Tax:11118"},{"id":"A312","pred":"tao:has_database_id","subj":"312","obj":"Tax:2559587"},{"id":"A313","pred":"tao:has_database_id","subj":"313","obj":"Tax:11118"},{"id":"A314","pred":"tao:has_database_id","subj":"314","obj":"Tax:11118"},{"id":"A315","pred":"tao:has_database_id","subj":"315","obj":"Tax:11118"},{"id":"A316","pred":"tao:has_database_id","subj":"316","obj":"Tax:694002"},{"id":"A317","pred":"tao:has_database_id","subj":"317","obj":"Tax:11118"},{"id":"A318","pred":"tao:has_database_id","subj":"318","obj":"Tax:11118"},{"id":"A319","pred":"tao:has_database_id","subj":"319","obj":"Tax: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Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T36","span":{"begin":374,"end":382},"obj":"Disease"},{"id":"T37","span":{"begin":448,"end":457},"obj":"Disease"},{"id":"T38","span":{"begin":467,"end":486},"obj":"Disease"},{"id":"T39","span":{"begin":695,"end":703},"obj":"Disease"},{"id":"T40","span":{"begin":708,"end":716},"obj":"Disease"},{"id":"T41","span":{"begin":763,"end":771},"obj":"Disease"},{"id":"T42","span":{"begin":924,"end":946},"obj":"Disease"},{"id":"T43","span":{"begin":1039,"end":1043},"obj":"Disease"},{"id":"T44","span":{"begin":1101,"end":1111},"obj":"Disease"},{"id":"T45","span":{"begin":1194,"end":1202},"obj":"Disease"},{"id":"T46","span":{"begin":1204,"end":1212},"obj":"Disease"},{"id":"T47","span":{"begin":1445,"end":1453},"obj":"Disease"},{"id":"T48","span":{"begin":1557,"end":1561},"obj":"Disease"},{"id":"T49","span":{"begin":1611,"end":1619},"obj":"Disease"},{"id":"T50","span":{"begin":1704,"end":1712},"obj":"Disease"},{"id":"T51","span":{"begin":1734,"end":1742},"obj":"Disease"},{"id":"T52","span":{"begin":1802,"end":1811},"obj":"Disease"},{"id":"T53","span":{"begin":1813,"end":1821},"obj":"Disease"},{"id":"T54","span":{"begin":1911,"end":1919},"obj":"Disease"},{"id":"T55","span":{"begin":1962,"end":1970},"obj":"Disease"}],"attributes":[{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0005087"},{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0024355"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A47","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A50","pred":"mondo_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A51","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A53","pred":"mondo_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A54","pred":"mondo_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A55","pred":"mondo_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T89","span":{"begin":314,"end":316},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T90","span":{"begin":494,"end":499},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T91","span":{"begin":500,"end":504},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T92","span":{"begin":500,"end":504},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T93","span":{"begin":635,"end":638},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T94","span":{"begin":639,"end":640},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T95","span":{"begin":642,"end":643},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T96","span":{"begin":684,"end":685},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T97","span":{"begin":753,"end":754},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T98","span":{"begin":860,"end":862},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T99","span":{"begin":867,"end":873},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T100","span":{"begin":897,"end":903},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T101","span":{"begin":1044,"end":1049},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T102","span":{"begin":1095,"end":1100},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T103","span":{"begin":1280,"end":1281},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T104","span":{"begin":1318,"end":1325},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T105","span":{"begin":1374,"end":1376},"obj":"http://purl.obolibrary.org/obo/CLO_0007074"},{"id":"T106","span":{"begin":1374,"end":1376},"obj":"http://purl.obolibrary.org/obo/CLO_0051988"},{"id":"T107","span":{"begin":1477,"end":1478},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T108","span":{"begin":1553,"end":1556},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"},{"id":"T109","span":{"begin":1753,"end":1758},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T110","span":{"begin":1827,"end":1828},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T257","span":{"begin":1389,"end":1399},"obj":"Chemical"},{"id":"T258","span":{"begin":1509,"end":1519},"obj":"Chemical"}],"attributes":[{"id":"A257","pred":"chebi_id","subj":"T257","obj":"http://purl.obolibrary.org/obo/CHEBI_36976"},{"id":"A258","pred":"chebi_id","subj":"T258","obj":"http://purl.obolibrary.org/obo/CHEBI_36976"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T66","span":{"begin":0,"end":2},"obj":"Sentence"},{"id":"T67","span":{"begin":3,"end":25},"obj":"Sentence"},{"id":"T68","span":{"begin":26,"end":115},"obj":"Sentence"},{"id":"T69","span":{"begin":116,"end":166},"obj":"Sentence"},{"id":"T70","span":{"begin":167,"end":292},"obj":"Sentence"},{"id":"T71","span":{"begin":293,"end":356},"obj":"Sentence"},{"id":"T72","span":{"begin":357,"end":505},"obj":"Sentence"},{"id":"T73","span":{"begin":506,"end":618},"obj":"Sentence"},{"id":"T74","span":{"begin":619,"end":662},"obj":"Sentence"},{"id":"T75","span":{"begin":663,"end":719},"obj":"Sentence"},{"id":"T76","span":{"begin":720,"end":748},"obj":"Sentence"},{"id":"T77","span":{"begin":749,"end":888},"obj":"Sentence"},{"id":"T78","span":{"begin":889,"end":1094},"obj":"Sentence"},{"id":"T79","span":{"begin":1095,"end":1251},"obj":"Sentence"},{"id":"T80","span":{"begin":1252,"end":1297},"obj":"Sentence"},{"id":"T81","span":{"begin":1298,"end":1388},"obj":"Sentence"},{"id":"T82","span":{"begin":1389,"end":1620},"obj":"Sentence"},{"id":"T83","span":{"begin":1621,"end":1733},"obj":"Sentence"},{"id":"T84","span":{"begin":1734,"end":1812},"obj":"Sentence"},{"id":"T85","span":{"begin":1813,"end":1887},"obj":"Sentence"},{"id":"T86","span":{"begin":1888,"end":2024},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
2_test
{"project":"2_test","denotations":[{"id":"32604730-32469854-51943955","span":{"begin":314,"end":316},"obj":"32469854"},{"id":"32604730-16575523-51943956","span":{"begin":1087,"end":1089},"obj":"16575523"},{"id":"32604730-15034574-51943957","span":{"begin":1090,"end":1092},"obj":"15034574"},{"id":"32604730-31987001-51943958","span":{"begin":1729,"end":1731},"obj":"31987001"},{"id":"32604730-32007145-51943959","span":{"begin":2020,"end":2022},"obj":"32007145"},{"id":"T71467","span":{"begin":314,"end":316},"obj":"32469854"},{"id":"T30962","span":{"begin":1087,"end":1089},"obj":"16575523"},{"id":"T36307","span":{"begin":1090,"end":1092},"obj":"15034574"},{"id":"T68080","span":{"begin":1729,"end":1731},"obj":"31987001"},{"id":"T22771","span":{"begin":2020,"end":2022},"obj":"32007145"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}
LitCovid-PD-HP
{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":924,"end":946},"obj":"Phenotype"},{"id":"T4","span":{"begin":1802,"end":1811},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0011947"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"2. Classification of CoVs\nMammal- and avian-infectible CoVs consist of the broad-ranged subfamily of Coronavirinae. The ICTV recommended classification is as follows: Riboviria (Realm)—Nidovirales (Order)— Cornidovirineae (Suborder)—coronavirida (Family)—orthocoronavirinae—Coronavirus genus. The four CoV genera [11] are the α-CoV, β-CoV, γ-CoV and δ-CoV. The 2019-nCoV or SARS-CoV-2 belong to the β-CoV genus and are zoonotic and cause mammalian infection, causing respiratory disease in the human lung. The α-CoV and β-CoV genus target mammal hosts while the δ-CoV and γ-CoV genus target avians and certain mammals. The β-CoV genus has A, B, C and D lineages. Among these, lineage B includes SARS-CoV and SARS-CoV-2. Lineage C includes MERS-CoV. The B lineage SARS-CoV and C lineage MERS-CoV, which are classified as β-CoVs, exhibit lethal rates of 10% and 35% in humans, respectively.\nCoVs in humans are associated with respiratory infections such as colds with clinical importance, as experienced for the previous outbreak in 2003 of SARS-human CoV (HCoV), HCoV-HKU1 and HCoV-NL63 [12,13]. Human infectious HCoV includes seven species, including α-CoV (HCoV-NL63 and HCoV-229E) and β-CoV (SARS-CoV, SARS-CoV-2, HCoV-OC43, HCoV-HKU1 and MERS-CoV). CoV RNA sequences mutate at a high frequency. Among the known RNA viruses, CoVs bear the longest genome sizes of 26 to 32 kb length RNA. Nucleotide sequences of CoV ssRNA genomes isolated from COVID-19 patients in Wuhan show a high homology of 89% with the nucleotide sequence of the previously known bat SARS-like CoV-ZXC-21 strain and 89% with the previous SARS-CoV. The initial Wuhan CoV isolates belong to the β-CoV genus and were therefore termed SARS-CoV-2 or 2019-nCoV [14]. SARS-CoV-2 infects human respiratory tracts and causes outbreaks of pneumonia. SARS-CoV-2 is a novel CoV and originates from the Wuhan district in China. The genome sequence of SARS-CoV-2 exhibits 79% sequence homology with the SARS-CoV RNA sequence and 50% with the MERS-CoV sequence [15]."}