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PMC:7352545 / 80056-80835 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T236 26-29 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T237 26-29 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T238 213-216 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T239 213-216 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T240 250-253 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T241 250-253 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T242 370-373 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T243 370-373 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T244 487-490 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T245 487-490 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T768 30-35 Body_part denotes sugar http://purl.org/sig/ont/fma/fma82737
T769 73-80 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T770 120-124 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T771 148-155 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T772 271-278 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T773 599-611 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T774 616-628 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T775 637-650 Body_part denotes cell surfaces http://purl.org/sig/ont/fma/fma67653
T776 637-641 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T777 656-661 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T778 682-686 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T326 156-159 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T328 322-325 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T330 586-594 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1110 120-124 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1111 389-390 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1112 517-527 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T1113 637-641 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1114 682-686 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1115 702-703 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1116 771-778 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T95244 26-29 Chemical denotes GM1 http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110
T91399 73-80 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T75759 148-155 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T66644 213-216 Chemical denotes GM1 http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110
T616 250-253 Chemical denotes GM1 http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110
T69799 271-278 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T620 287-291 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T621 370-373 Chemical denotes GM1 http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110
T75682 375-378 Chemical denotes Asn http://purl.obolibrary.org/obo/CHEBI_17196|http://purl.obolibrary.org/obo/CHEBI_22653|http://purl.obolibrary.org/obo/CHEBI_50347
T45327 391-399 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T94022 414-420 Chemical denotes GalNAc http://purl.obolibrary.org/obo/CHEBI_28037|http://purl.obolibrary.org/obo/CHEBI_28800
T14276 450-453 Chemical denotes Phe http://purl.obolibrary.org/obo/CHEBI_17295|http://purl.obolibrary.org/obo/CHEBI_29997
T99238 472-475 Chemical denotes Glc http://purl.obolibrary.org/obo/CHEBI_17234
T633 487-490 Chemical denotes GM1 http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110
T31697 507-516 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T48080 599-611 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T638 616-628 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T639 656-661 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T640 687-689 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T643 752-757 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T770 0-141 Sentence denotes As CLQ interacts with the GM1 sugar part, the N-terminal domain of the S protein loses viral attachment capacity to the cell receptors [166].
T771 142-374 Sentence denotes The S protein NTD and the CLQ/CLQ-OH maintain the same position during GM1 binding, consequently preventing GM1 binding to the S protein and the drug at the same time, because the NTD and the CLQ/CLQ-OH simultaneously recognize GM1.
T772 375-491 Sentence denotes Asn-167 forms a hydrogen bond with the GalNAc residue, whereas an aromatic Phe-135 stacks to the Glc residue of GM1.
T773 492-651 Sentence denotes Therefore, the antiviral activities of CLQ and CLQ-OH is to block the interaction between the SARS-CoV-2 S glycoprotein and gangliosides on host cell surfaces.
T774 652-779 Sentence denotes The lipid composition of host cell PM can also be a potential target for preventive and therapeutic drugs against such viruses.

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T22 26-29 GlycoEpitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T23 213-216 GlycoEpitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T24 250-253 GlycoEpitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T25 370-373 GlycoEpitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T26 487-490 GlycoEpitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050

2_test

Id Subject Object Predicate Lexical cue
32604730-32293710-51944131 136-139 32293710 denotes 166
T9412 136-139 32293710 denotes 166