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PMC:7352545 / 7608-8590 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T23 190-192 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T24 199-205 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T25 267-269 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T26 341-365 https://glytoucan.org/Structures/Glycans/G50850NI denotes N-acetyl neuraminic acid
T27 341-365 https://glytoucan.org/Structures/Glycans/G81533KY denotes N-acetyl neuraminic acid
T28 630-632 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T29 643-645 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T30 710-712 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T31 775-777 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T32 786-788 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T33 968-970 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T45 57-63 Body_part denotes sugars http://purl.org/sig/ont/fma/fma82737
T46 85-91 Body_part denotes sugars http://purl.org/sig/ont/fma/fma82737
T47 341-365 Body_part denotes N-acetyl neuraminic acid http://purl.org/sig/ont/fma/fma82788

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
259 684-688 Gene denotes α2-6 Gene:10312
260 451-457 Species denotes horses Tax:9796
261 500-507 Species denotes bovines Tax:9913
262 560-567 Species denotes bovines Tax:9913
263 801-805 Gene denotes α2,3 Gene:28923
264 813-817 Gene denotes α2,6 Gene:170589
265 6-12 Chemical denotes carbon MESH:D002244
266 57-63 Chemical denotes sugars MESH:D000073893
267 85-91 Chemical denotes sugars MESH:D000073893
268 127-132 Chemical denotes NeuAc MESH:D009438
269 317-332 Chemical denotes neuraminic acid MESH:D009438
270 334-338 Chemical denotes NeuC MESH:D009438
271 341-365 Chemical denotes N-acetyl neuraminic acid
272 367-372 Chemical denotes NeuAc MESH:D009438
273 375-401 Chemical denotes N-glycolyl neuraminic acid
274 403-408 Chemical denotes NeuGc
275 411-439 Chemical denotes N,O-diacetyl neuraminic acid
276 460-488 Chemical denotes N,O-diacetyl neuraminic acid
277 513-548 Chemical denotes N-acetyl O-diacetyl neuraminic acid
278 716-719 Chemical denotes Gal MESH:C101993
279 848-863 Chemical denotes Galβ-1,4-GlcNAc

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T75 13-16 http://purl.obolibrary.org/obo/CLO_0051568 denotes SAs
T76 28-34 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T77 93-96 http://purl.obolibrary.org/obo/CLO_0051568 denotes SAs
T78 143-144 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T79 207-210 http://purl.obolibrary.org/obo/CLO_0051568 denotes SAs
T80 451-457 http://purl.obolibrary.org/obo/NCBITaxon_9796 denotes horses
T81 806-808 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T82 806-808 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T83 818-820 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T84 818-820 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T85 910-913 http://purl.obolibrary.org/obo/CLO_0051568 denotes SAs
T86 947-949 http://purl.obolibrary.org/obo/CLO_0037284 denotes C4
T87 951-953 http://purl.obolibrary.org/obo/CLO_0002147 denotes C7
T88 951-953 http://purl.obolibrary.org/obo/CLO_0051562 denotes C7

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T178 6-12 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T180 117-122 Chemical denotes NeuGc http://purl.obolibrary.org/obo/CHEBI_62084
T181 127-132 Chemical denotes NeuAc http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018
T183 134-139 Chemical denotes NeuGc http://purl.obolibrary.org/obo/CHEBI_62084
T184 190-192 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T189 199-205 Chemical denotes Neu5Ac http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133
T191 267-269 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T196 317-332 Chemical denotes neuraminic acid http://purl.obolibrary.org/obo/CHEBI_49018
T197 328-332 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T198 334-338 Chemical denotes NeuC http://purl.obolibrary.org/obo/CHEBI_49018
T199 341-365 Chemical denotes N-acetyl neuraminic acid http://purl.obolibrary.org/obo/CHEBI_17012
T200 343-349 Chemical denotes acetyl http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887
T202 350-365 Chemical denotes neuraminic acid http://purl.obolibrary.org/obo/CHEBI_49018
T203 361-365 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T204 367-372 Chemical denotes NeuAc http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018
T206 377-385 Chemical denotes glycolyl http://purl.obolibrary.org/obo/CHEBI_30884
T207 386-401 Chemical denotes neuraminic acid http://purl.obolibrary.org/obo/CHEBI_49018
T208 397-401 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T209 403-408 Chemical denotes NeuGc http://purl.obolibrary.org/obo/CHEBI_62084
T210 415-423 Chemical denotes diacetyl http://purl.obolibrary.org/obo/CHEBI_16583
T211 424-439 Chemical denotes neuraminic acid http://purl.obolibrary.org/obo/CHEBI_49018
T212 435-439 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T213 464-472 Chemical denotes diacetyl http://purl.obolibrary.org/obo/CHEBI_16583
T214 473-488 Chemical denotes neuraminic acid http://purl.obolibrary.org/obo/CHEBI_49018
T215 484-488 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T216 515-521 Chemical denotes acetyl http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887
T218 524-532 Chemical denotes diacetyl http://purl.obolibrary.org/obo/CHEBI_16583
T219 533-548 Chemical denotes neuraminic acid http://purl.obolibrary.org/obo/CHEBI_49018
T220 544-548 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T221 630-632 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T226 643-645 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T231 710-712 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T236 716-719 Chemical denotes Gal http://purl.obolibrary.org/obo/CHEBI_28260
T237 775-777 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T242 786-788 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T247 806-808 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T248 818-820 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T249 848-851 Chemical denotes Gal http://purl.obolibrary.org/obo/CHEBI_28260
T250 857-863 Chemical denotes GlcNAc http://purl.obolibrary.org/obo/CHEBI_506227|http://purl.obolibrary.org/obo/CHEBI_73685
T252 968-970 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T8 757-766 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T57 0-92 Sentence denotes The 9-carbon SAs are mainly animal-specific with anionic sugars attached to terminal sugars.
T58 93-133 Sentence denotes SAs exist in two forms, NeuGc and NeuAc.
T59 134-206 Sentence denotes NeuGc is a differentially modified form of the parental SA form, Neu5Ac.
T60 207-236 Sentence denotes SAs are structurally diverse.
T61 237-580 Sentence denotes For example, several modified SA forms are known for their structures including neuraminic acid (NeuC), N-acetyl neuraminic acid (NeuAc), N-glycolyl neuraminic acid (NeuGc), N,O-diacetyl neuraminic acid (occurs in horses), N,O-diacetyl neuraminic acid (occurs in bovines) and N-acetyl O-diacetyl neuraminic acid (occurs in bovines) (Figure 2).
T62 581-642 Sentence denotes Sialyltransferases (STs) biosynthesize different SA linkages.
T63 643-740 Sentence denotes SA linkage diversity occurs at the α2-3, α2-6, α2-8 or α2-9 to the SA or Gal residues (Figure 3).
T64 741-875 Sentence denotes For example, in formation of α2,3 SA or α2,6 SA structures, α2,3-ST and α2,6-ST utilize substrates such as Galβ-1,4-GlcNAc (Figure 4).
T65 876-982 Sentence denotes The most frequent modification of SAs is O-acetylation at positions of C4, C7, C8 and C9 of SA (Figure 5).