PMC:7352545 / 31565-32535
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T121 | 147-149 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T122 | 209-211 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T123 | 257-263 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T124 | 365-367 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T125 | 393-395 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T126 | 572-574 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T127 | 619-621 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T128 | 654-656 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T129 | 868-870 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T130 | 937-939 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T253 | 25-33 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T254 | 422-435 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T255 | 532-544 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T256 | 713-725 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T257 | 776-781 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T258 | 833-838 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T259 | 921-933 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T260 | 964-969 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T115 | 84-101 | Disease | denotes | encephalomyelitis | http://purl.obolibrary.org/obo/MONDO_0005156 |
| T116 | 788-797 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T422 | 102-107 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T423 | 205-208 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T424 | 307-310 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T425 | 329-332 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T426 | 524-531 | http://purl.obolibrary.org/obo/NCBITaxon_9031 | denotes | chicken |
| T427 | 532-544 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T428 | 584-586 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T429 | 677-678 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T430 | 776-781 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T431 | 833-838 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T432 | 964-969 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T913 | 25-33 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T914 | 147-149 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T919 | 209-211 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T924 | 257-263 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T926 | 304-306 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T928 | 326-328 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T930 | 365-367 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T935 | 393-395 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T940 | 422-435 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T941 | 569-571 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T943 | 572-574 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T948 | 619-621 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T953 | 651-653 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T955 | 654-656 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T960 | 713-725 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T961 | 844-846 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T962 | 868-870 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T967 | 921-933 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T968 | 937-939 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T52 | 950-963 | http://purl.obolibrary.org/obo/GO_0044409 | denotes | entry to host |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T309 | 0-189 | Sentence | denotes | The first coronaviral HE proteins identified were from the porcine hemagglutinating encephalomyelitis virus (PHEV), BCoV and HCoV-OC43, which bear SA-9-O-acetylesterases similar to HEF [8]. |
| T310 | 190-275 | Sentence | denotes | Rat CoV (RCoV) has SA-4-O-acetylesterases, converting Neu4,5Ac2 to Neu5Ac [53,57,58]. |
| T311 | 276-333 | Sentence | denotes | Some murine CoVs prefer 4-O-Ac-SAs and others 9-O-Ac-SAs. |
| T312 | 334-415 | Sentence | denotes | HCoV-OC43 and BCoV prefer α2-6-SA 9-O-acetylation by their SA-O-acetyleseterases. |
| T313 | 416-588 | Sentence | denotes | The S glycoproteins of BCoV and HCoV-OC43 are Neu5,9Ac2-recognizing lectins and agglutinate murine, rat and chicken erythrocytes due to the enriched 9-O-Ac-SA species [52]. |
| T314 | 589-672 | Sentence | denotes | BCoV and HCoV-OC43 adapted to SA receptor determinants of 9-O-Ac-SA receptors [59]. |
| T315 | 673-782 | Sentence | denotes | For a second receptor, the binding of S glycoprotein to Neu5,9Ac2 receptor is essential for entry into cells. |
| T316 | 783-970 | Sentence | denotes | BCoV-infection is prevented by prior treatment of cells with NA enzyme or with viral SA-O-acetylesterases, blocking the roles of HE and S glycoprotein in SA-dependent entry to host cells. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-3380803-51944000 | 186-187 | 3380803 | denotes | 8 |
| 32604730-10233932-51944001 | 265-267 | 10233932 | denotes | 53 |
| 32604730-11807232-51944002 | 268-270 | 11807232 | denotes | 57 |
| 32604730-1920630-51944003 | 584-586 | 1920630 | denotes | 52 |
| 32604730-1321878-51944004 | 668-670 | 1321878 | denotes | 59 |
| T74157 | 186-187 | 3380803 | denotes | 8 |
| T77726 | 265-267 | 10233932 | denotes | 53 |
| T52426 | 268-270 | 11807232 | denotes | 57 |
| T22208 | 584-586 | 1920630 | denotes | 52 |
| T60367 | 668-670 | 1321878 | denotes | 59 |