PMC:7352545 / 20518-21274
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T55 | 81-83 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T56 | 234-236 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T57 | 301-303 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T58 | 430-432 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T59 | 686-692 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T209 | 449-464 | Body_part | denotes | Golgi apparatus | http://purl.org/sig/ont/fma/fma63843 |
T210 | 465-476 | Body_part | denotes | compartment | http://purl.org/sig/ont/fma/fma76577 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T240 | 56-59 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C-4 |
T241 | 61-64 | http://purl.obolibrary.org/obo/CLO_0002147 | denotes | C-7 |
T242 | 61-64 | http://purl.obolibrary.org/obo/CLO_0051562 | denotes | C-7 |
T243 | 165-168 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T244 | 184-185 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T245 | 250-253 | http://purl.obolibrary.org/obo/CLO_0002147 | denotes | C-7 |
T246 | 250-253 | http://purl.obolibrary.org/obo/CLO_0051562 | denotes | C-7 |
T247 | 332-336 | http://purl.obolibrary.org/obo/CLO_0002200 | denotes | Cas1 |
T248 | 430-434 | http://purl.obolibrary.org/obo/UBERON_0009856 | denotes | SA C |
T249 | 565-568 | http://purl.obolibrary.org/obo/CLO_0002147 | denotes | C-7 |
T250 | 565-568 | http://purl.obolibrary.org/obo/CLO_0051562 | denotes | C-7 |
T251 | 598-601 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T252 | 655-661 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | A as a |
T253 | 733-741 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T461 | 6-12 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
T463 | 81-83 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T468 | 234-236 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T473 | 237-244 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
T474 | 301-303 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T479 | 409-415 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
T481 | 430-432 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T486 | 547-553 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
T488 | 554-559 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T489 | 639-645 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
T491 | 646-656 | Chemical | denotes | coenzyme A | http://purl.obolibrary.org/obo/CHEBI_15346 |
T492 | 646-654 | Chemical | denotes | coenzyme | http://purl.obolibrary.org/obo/CHEBI_23354 |
T493 | 662-667 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
T494 | 682-692 | Chemical | denotes | CMP-Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_16556 |
T495 | 682-685 | Chemical | denotes | CMP | http://purl.obolibrary.org/obo/CHEBI_17361|http://purl.obolibrary.org/obo/CHEBI_60377 |
T497 | 686-692 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T499 | 699-707 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
T500 | 745-755 | Chemical | denotes | CMP-Neu5Gc | http://purl.obolibrary.org/obo/CHEBI_18098 |
T501 | 745-748 | Chemical | denotes | CMP | http://purl.obolibrary.org/obo/CHEBI_17361|http://purl.obolibrary.org/obo/CHEBI_60377 |
T503 | 749-755 | Chemical | denotes | Neu5Gc | http://purl.obolibrary.org/obo/CHEBI_62084 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T197 | 0-169 | Sentence | denotes | The O-acetyl modification occurs in single positions of C-4, C-7, C-8 and C-9 of SA as well as in combined C-positions to yield Neu4,5Ac2, Neu5,9Ac2 and Neu5,7,9Ac3 SAs. |
T198 | 170-245 | Sentence | denotes | Neu5Ac9NAc is a chemical and biologic mimic of Neu5,9Ac2 in the SA-glycans. |
T199 | 246-376 | Sentence | denotes | The C-7 and/or C-9 O-acetylations are catalyzed by the SA O-acetyltransferase enzyme, Cas1 domain containing 1 (CasD1) (Figure 6). |
T200 | 377-482 | Sentence | denotes | CasD1 catalyzes the addition of acetyl groups to the SA C-7 at the late Golgi apparatus compartment [31]. |
T201 | 483-627 | Sentence | denotes | Thereafter, an enzyme termed “migrase” transfers the additional acetyl-group from C-7 to C-9, although this enzyme has not been identified [29]. |
T202 | 628-756 | Sentence | denotes | CasD1 uses acetyl-coenzyme A as a donor substrate and CMP-Neu5Ac as an acceptor substrate, but with weak activity on CMP-Neu5Gc. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32604730-26169044-51943971 | 478-480 | 26169044 | denotes | 31 |
T96738 | 478-480 | 26169044 | denotes | 31 |