PMC:7352545 / 14469-15729
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T121 | 29-41 | Body_part | denotes | Glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T122 | 45-48 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T123 | 64-76 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T124 | 104-111 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T125 | 215-217 | Body_part | denotes | ER | http://purl.org/sig/ont/fma/fma63842 |
T126 | 226-231 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T127 | 246-258 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T128 | 329-341 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T129 | 386-398 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T130 | 459-464 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T131 | 518-530 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T132 | 585-597 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T133 | 637-649 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T134 | 719-731 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T135 | 818-822 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T136 | 955-968 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
T137 | 955-959 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T138 | 991-1000 | Body_part | denotes | cytosolic | http://purl.org/sig/ont/fma/fma66836 |
T139 | 1146-1158 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
T140 | 1233-1240 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
471 | 5-10 | Gene | denotes | Spike | Gene:43740568 |
486 | 753-758 | Gene | denotes | spike | Gene:43740568 |
487 | 369-370 | Gene | denotes | N | Gene:43740575 |
488 | 268-269 | Gene | denotes | N | Gene:43740575 |
489 | 384-385 | Gene | denotes | S | Gene:43740568 |
490 | 327-328 | Gene | denotes | S | Gene:43740568 |
491 | 244-245 | Gene | denotes | S | Gene:43740568 |
492 | 1212-1215 | Gene | denotes | CTD | Gene:1283 |
493 | 613-618 | Gene | denotes | spike | Gene:43740568 |
494 | 233-243 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
495 | 493-497 | Species | denotes | CoVs | Tax:11118 |
496 | 1011-1019 | Species | denotes | SARS-CoV | Tax:694009 |
497 | 1024-1032 | Species | denotes | MERS-CoV | Tax:1335626 |
498 | 1146-1158 | Chemical | denotes | carbohydrate | MESH:D002241 |
499 | 472-481 | Disease | denotes | infection | MESH:D007239 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T60 | 161-164 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
T62 | 233-241 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T63 | 472-481 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T64 | 1011-1019 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T65 | 1133-1136 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T154 | 49-56 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T155 | 226-231 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T156 | 265-267 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T157 | 443-448 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T158 | 459-464 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T159 | 506-507 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T160 | 598-601 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T161 | 602-603 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T162 | 678-679 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T163 | 766-774 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T164 | 798-803 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T165 | 818-822 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T166 | 824-826 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T167 | 863-865 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T168 | 870-872 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T169 | 870-872 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T170 | 882-883 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T171 | 884-886 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T172 | 887-889 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T173 | 887-889 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T174 | 905-907 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T175 | 911-912 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T176 | 955-959 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T177 | 960-968 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T178 | 973-975 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T179 | 973-975 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T180 | 1038-1040 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T181 | 1072-1073 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T182 | 1087-1092 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T183 | 1130-1132 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T184 | 1181-1183 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T185 | 1219-1221 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T297 | 29-41 | Chemical | denotes | Glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T298 | 64-76 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T299 | 104-111 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T300 | 246-258 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T301 | 268-276 | Chemical | denotes | N-glycan | http://purl.obolibrary.org/obo/CHEBI_59520 |
T302 | 329-341 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T303 | 369-378 | Chemical | denotes | N-glycans | http://purl.obolibrary.org/obo/CHEBI_59520 |
T304 | 371-378 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
T305 | 386-398 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T306 | 518-530 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T307 | 585-597 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T308 | 637-649 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T309 | 719-731 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T310 | 766-774 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
T311 | 870-872 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T312 | 887-889 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T313 | 973-975 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T314 | 1146-1158 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
T315 | 1233-1240 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T126 | 0-4 | Sentence | denotes | 3.1. |
T127 | 5-41 | Sentence | denotes | Spike (S) Transmembrane Glycoprotein |
T128 | 42-82 | Sentence | denotes | In RNA viruses, the S glycoprotein (PDB: |
T129 | 83-232 | Sentence | denotes | 6VSB) is the biggest protein, heavily glycosylated and its N-terminal domain (NTD) sequence binds to the host receptor to enter the ER of host cells. |
T130 | 233-302 | Sentence | denotes | SARS-CoV-2 S-glycoprotein bears 22 N-glycan sequons in each protomer. |
T131 | 303-379 | Sentence | denotes | Therefore, the trimeric S glycoprotein surface is dominated by 66 N-glycans. |
T132 | 380-488 | Sentence | denotes | The S glycoprotein mediates direct and indirect interaction of virus with host cells in the infection cycle. |
T133 | 489-578 | Sentence | denotes | All CoVs exhibit a surface S glycoprotein, which bears the receptor-binding domain (RBD). |
T134 | 579-629 | Sentence | denotes | The S glycoprotein has a distinct spike structure. |
T135 | 630-828 | Sentence | denotes | When S glycoprotein binds to its host receptor, a host furin-like protease cleaves the S glycoprotein, which liberates the spike fusion peptides, allowing entry of the virus into the host cell [18]. |
T136 | 829-1006 | Sentence | denotes | The furin-like protease-generated S1 and S2 exist as a S1/S2 complex, where S1 in a homotrimeric form interacts with the host cell membrane and S2 penetrates the cytosolic area. |
T137 | 1007-1125 | Sentence | denotes | For SARS-CoV and MERS-CoV, the S1 C-terminal domains (CTDs) have a dual role in virus entry via attachment and fusion. |
T138 | 1126-1207 | Sentence | denotes | The S1 NTD binds to carbohydrate receptors because the S1 domains act as the RBD. |
T139 | 1208-1260 | Sentence | denotes | The CTD of S1 recognizes protein receptors via RBDs. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32604730-24121034-51943962 | 824-826 | 24121034 | denotes | 18 |
T51478 | 824-826 | 24121034 | denotes | 18 |