PMC:7352545 / 11353-12446 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T73","span":{"begin":48,"end":54},"obj":"Body_part"},{"id":"T74","span":{"begin":176,"end":183},"obj":"Body_part"},{"id":"T75","span":{"begin":206,"end":212},"obj":"Body_part"},{"id":"T76","span":{"begin":244,"end":249},"obj":"Body_part"},{"id":"T77","span":{"begin":292,"end":299},"obj":"Body_part"},{"id":"T78","span":{"begin":355,"end":367},"obj":"Body_part"},{"id":"T79","span":{"begin":409,"end":421},"obj":"Body_part"},{"id":"T80","span":{"begin":433,"end":436},"obj":"Body_part"},{"id":"T81","span":{"begin":458,"end":466},"obj":"Body_part"},{"id":"T82","span":{"begin":489,"end":497},"obj":"Body_part"},{"id":"T83","span":{"begin":524,"end":532},"obj":"Body_part"},{"id":"T84","span":{"begin":614,"end":627},"obj":"Body_part"},{"id":"T85","span":{"begin":635,"end":647},"obj":"Body_part"},{"id":"T86","span":{"begin":660,"end":667},"obj":"Body_part"},{"id":"T87","span":{"begin":722,"end":727},"obj":"Body_part"},{"id":"T88","span":{"begin":749,"end":757},"obj":"Body_part"},{"id":"T89","span":{"begin":776,"end":797},"obj":"Body_part"},{"id":"T90","span":{"begin":799,"end":801},"obj":"Body_part"},{"id":"T91","span":{"begin":834,"end":855},"obj":"Body_part"},{"id":"T92","span":{"begin":875,"end":886},"obj":"Body_part"},{"id":"T93","span":{"begin":900,"end":903},"obj":"Body_part"},{"id":"T94","span":{"begin":904,"end":910},"obj":"Body_part"}],"attributes":[{"id":"A73","pred":"fma_id","subj":"T73","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A74","pred":"fma_id","subj":"T74","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A75","pred":"fma_id","subj":"T75","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A76","pred":"fma_id","subj":"T76","obj":"http://purl.org/sig/ont/fma/fma67264"},{"id":"A77","pred":"fma_id","subj":"T77","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A79","pred":"fma_id","subj":"T79","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A81","pred":"fma_id","subj":"T81","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A82","pred":"fma_id","subj":"T82","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A84","pred":"fma_id","subj":"T84","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A85","pred":"fma_id","subj":"T85","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A86","pred":"fma_id","subj":"T86","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A87","pred":"fma_id","subj":"T87","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A88","pred":"fma_id","subj":"T88","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A89","pred":"fma_id","subj":"T89","obj":"http://purl.org/sig/ont/fma/fma63842"},{"id":"A90","pred":"fma_id","subj":"T90","obj":"http://purl.org/sig/ont/fma/fma63842"},{"id":"A91","pred":"fma_id","subj":"T91","obj":"http://purl.org/sig/ont/fma/fma63842"},{"id":"A92","pred":"fma_id","subj":"T92","obj":"http://purl.org/sig/ont/fma/fma76577"},{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma84116"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}

{"project":"LitCovid-PubTator","denotations":[{"id":"449","span":{"begin":423,"end":424},"obj":"Gene"},{"id":"450","span":{"begin":747,"end":748},"obj":"Gene"},{"id":"451","span":{"begin":487,"end":488},"obj":"Gene"},{"id":"452","span":{"begin":369,"end":370},"obj":"Gene"},{"id":"453","span":{"begin":741,"end":742},"obj":"Gene"},{"id":"454","span":{"begin":606,"end":607},"obj":"Gene"},{"id":"455","span":{"begin":481,"end":482},"obj":"Gene"},{"id":"456","span":{"begin":603,"end":604},"obj":"Gene"},{"id":"457","span":{"begin":478,"end":479},"obj":"Gene"},{"id":"458","span":{"begin":427,"end":428},"obj":"Gene"},{"id":"459","span":{"begin":230,"end":238},"obj":"Gene"},{"id":"460","span":{"begin":95,"end":103},"obj":"Gene"},{"id":"461","span":{"begin":311,"end":320},"obj":"Species"},{"id":"462","span":{"begin":322,"end":332},"obj":"Species"},{"id":"463","span":{"begin":345,"end":350},"obj":"Gene"}],"attributes":[{"id":"A449","pred":"tao:has_database_id","subj":"449","obj":"Gene:43740571"},{"id":"A450","pred":"tao:has_database_id","subj":"450","obj":"Gene:43740570"},{"id":"A451","pred":"tao:has_database_id","subj":"451","obj":"Gene:43740570"},{"id":"A452","pred":"tao:has_database_id","subj":"452","obj":"Gene:43740570"},{"id":"A453","pred":"tao:has_database_id","subj":"453","obj":"Gene:43740571"},{"id":"A454","pred":"tao:has_database_id","subj":"454","obj":"Gene:43740571"},{"id":"A455","pred":"tao:has_database_id","subj":"455","obj":"Gene:43740571"},{"id":"A456","pred":"tao:has_database_id","subj":"456","obj":"Gene:43740575"},{"id":"A457","pred":"tao:has_database_id","subj":"457","obj":"Gene:43740575"},{"id":"A458","pred":"tao:has_database_id","subj":"458","obj":"Gene:43740575"},{"id":"A459","pred":"tao:has_database_id","subj":"459","obj":"Gene:43740570"},{"id":"A460","pred":"tao:has_database_id","subj":"460","obj":"Gene:43740570"},{"id":"A461","pred":"tao:has_database_id","subj":"461","obj":"Tax:2697049"},{"id":"A462","pred":"tao:has_database_id","subj":"462","obj":"Tax:2697049"},{"id":"A463","pred":"tao:has_database_id","subj":"463","obj":"Gene:43740568"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T58","span":{"begin":322,"end":330},"obj":"Disease"}],"attributes":[{"id":"A58","pred":"mondo_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T120","span":{"begin":121,"end":122},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T121","span":{"begin":123,"end":128},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T122","span":{"begin":134,"end":135},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T123","span":{"begin":149,"end":152},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T124","span":{"begin":153,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T125","span":{"begin":214,"end":221},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T126","span":{"begin":343,"end":344},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T127","span":{"begin":391,"end":392},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T128","span":{"begin":393,"end":401},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T129","span":{"begin":651,"end":652},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T130","span":{"begin":722,"end":727},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T131","span":{"begin":803,"end":811},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T132","span":{"begin":965,"end":970},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T263","span":{"begin":176,"end":183},"obj":"Chemical"},{"id":"T264","span":{"begin":244,"end":249},"obj":"Chemical"},{"id":"T265","span":{"begin":292,"end":299},"obj":"Chemical"},{"id":"T266","span":{"begin":355,"end":367},"obj":"Chemical"},{"id":"T267","span":{"begin":409,"end":421},"obj":"Chemical"},{"id":"T268","span":{"begin":458,"end":466},"obj":"Chemical"},{"id":"T269","span":{"begin":489,"end":497},"obj":"Chemical"},{"id":"T270","span":{"begin":524,"end":532},"obj":"Chemical"},{"id":"T271","span":{"begin":614,"end":627},"obj":"Chemical"},{"id":"T272","span":{"begin":635,"end":647},"obj":"Chemical"},{"id":"T273","span":{"begin":660,"end":667},"obj":"Chemical"},{"id":"T274","span":{"begin":749,"end":757},"obj":"Chemical"}],"attributes":[{"id":"A263","pred":"chebi_id","subj":"T263","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A264","pred":"chebi_id","subj":"T264","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A265","pred":"chebi_id","subj":"T265","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A266","pred":"chebi_id","subj":"T266","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A267","pred":"chebi_id","subj":"T267","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A268","pred":"chebi_id","subj":"T268","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A269","pred":"chebi_id","subj":"T269","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A270","pred":"chebi_id","subj":"T270","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A271","pred":"chebi_id","subj":"T271","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A272","pred":"chebi_id","subj":"T272","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A273","pred":"chebi_id","subj":"T273","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A274","pred":"chebi_id","subj":"T274","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T11","span":{"begin":1000,"end":1011},"obj":"http://purl.obolibrary.org/obo/GO_0006810"},{"id":"T12","span":{"begin":1082,"end":1092},"obj":"http://purl.obolibrary.org/obo/GO_0006887"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}

{"project":"LitCovid-sentences","denotations":[{"id":"T95","span":{"begin":0,"end":120},"obj":"Sentence"},{"id":"T96","span":{"begin":121,"end":213},"obj":"Sentence"},{"id":"T97","span":{"begin":214,"end":306},"obj":"Sentence"},{"id":"T98","span":{"begin":307,"end":442},"obj":"Sentence"},{"id":"T99","span":{"begin":443,"end":592},"obj":"Sentence"},{"id":"T100","span":{"begin":593,"end":733},"obj":"Sentence"},{"id":"T101","span":{"begin":734,"end":895},"obj":"Sentence"},{"id":"T102","span":{"begin":896,"end":981},"obj":"Sentence"},{"id":"T103","span":{"begin":982,"end":1093},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}

{"project":"2_test","denotations":[{"id":"32604730-32290293-51943960","span":{"begin":438,"end":440},"obj":"32290293"},{"id":"32604730-32288441-51943961","span":{"begin":729,"end":731},"obj":"32288441"},{"id":"T87050","span":{"begin":438,"end":440},"obj":"32290293"},{"id":"T12608","span":{"begin":729,"end":731},"obj":"32288441"}],"text":"Generally, viral families are determined by the genome structure and virion morphologies of an envelope or naked capsid. A virus with a naked capsid has a coat of nucleocapsid protein (N) coating the viral genome. Viruses with an envelope have lipid envelopes further surrounding the outmost protein layer. The 2019-nCoV (SARS-CoV-2) contains a spike (S) glycoprotein, E, dimeric HE enzyme, a membrane matrix glycoprotein (M), N and RNA [16]. The structural proteins are the S, N, M and E proteins, while the non-structural proteins are proteases such as Nsp3 and Nsp5 and RdRp such as Nsp12. Among the N, M and S glycoproteins, the S glycoprotein is a fusion protein that recognizes the host receptor and enters the host cells [17]. The S, M and E proteins anchored into the endoplasmic reticulum (ER) membrane are trafficked to the endoplasmic reticulum–Golgi intermediate compartment (ERGIC). The RNA genome linked with nucleoprotein buds into the ERGIC to form virus particles. Assembled virions transported to the vesicular surface are released to the extracellular milieu via exocytosis."}