PMC:7346000 / 13734-14292 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T41","span":{"begin":199,"end":202},"obj":"Body_part"},{"id":"T42","span":{"begin":519,"end":532},"obj":"Body_part"}],"attributes":[{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma7199"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma9825"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T9","span":{"begin":519,"end":532},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0002405"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"392","span":{"begin":72,"end":80},"obj":"Species"},{"id":"393","span":{"begin":152,"end":160},"obj":"Species"},{"id":"394","span":{"begin":193,"end":198},"obj":"Species"},{"id":"395","span":{"begin":199,"end":213},"obj":"Species"},{"id":"396","span":{"begin":143,"end":151},"obj":"Disease"},{"id":"397","span":{"begin":483,"end":509},"obj":"Disease"}],"attributes":[{"id":"A392","pred":"tao:has_database_id","subj":"392","obj":"Tax:9606"},{"id":"A393","pred":"tao:has_database_id","subj":"393","obj":"Tax:9606"},{"id":"A394","pred":"tao:has_database_id","subj":"394","obj":"Tax:9606"},{"id":"A395","pred":"tao:has_database_id","subj":"395","obj":"Tax:749906"},{"id":"A396","pred":"tao:has_database_id","subj":"396","obj":"MESH:C000657245"},{"id":"A397","pred":"tao:has_database_id","subj":"397","obj":"MESH:D000072742"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T144","span":{"begin":143,"end":151},"obj":"Disease"},{"id":"T145","span":{"begin":492,"end":509},"obj":"Disease"}],"attributes":[{"id":"A144","pred":"mondo_id","subj":"T144","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A145","pred":"mondo_id","subj":"T145","obj":"http://purl.obolibrary.org/obo/MONDO_0002041"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T96","span":{"begin":193,"end":198},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T97","span":{"begin":199,"end":202},"obj":"http://purl.obolibrary.org/obo/UBERON_0001007"},{"id":"T98","span":{"begin":199,"end":202},"obj":"http://purl.obolibrary.org/obo/UBERON_0001555"},{"id":"T99","span":{"begin":199,"end":202},"obj":"http://www.ebi.ac.uk/efo/EFO_0000834"},{"id":"T100","span":{"begin":217,"end":218},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T101","span":{"begin":251,"end":259},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T102","span":{"begin":280,"end":288},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T103","span":{"begin":519,"end":532},"obj":"http://purl.obolibrary.org/obo/UBERON_0002405"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T83","span":{"begin":51,"end":61},"obj":"Chemical"},{"id":"T84","span":{"begin":97,"end":108},"obj":"Chemical"},{"id":"T85","span":{"begin":346,"end":357},"obj":"Chemical"}],"attributes":[{"id":"A83","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_33281"},{"id":"A84","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_33281"},{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_33281"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T35","span":{"begin":483,"end":509},"obj":"Phenotype"}],"attributes":[{"id":"A35","pred":"hp_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/HP_0020101"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T71","span":{"begin":0,"end":182},"obj":"Sentence"},{"id":"T72","span":{"begin":183,"end":558},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}

{"project":"2_test","denotations":[{"id":"32599813-30987351-60095113","span":{"begin":551,"end":553},"obj":"30987351"},{"id":"32599813-31222314-60095114","span":{"begin":554,"end":556},"obj":"31222314"}],"text":"Although detailed case series have not reported on antibiotic use among patients, broad-spectrum antibiotics are presumed to be used in 75% of COVID-19 patients admitted to ICU [49]. Since the human gut microbiome is a highly complicated structure of bacteria and fungi, although bacteria are the most diverse constituents, the administration of antibiotics results in perturbation of microbiome steady-state composition, which allows fungi to thrive, and may predispose the host to invasive fungal infections once the immune system becomes impaired [65,66]."}