PMC:7340597 / 17067-19063
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T21 | 997-999 | https://glytoucan.org/Structures/Glycans/G93424OB | denotes | GM |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T100 | 22-30 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T101 | 142-147 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T102 | 521-526 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T103 | 787-791 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T104 | 1205-1209 | Body_part | denotes | head | http://purl.org/sig/ont/fma/fma7154 |
| T105 | 1435-1439 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T106 | 1440-1446 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T107 | 1565-1576 | Body_part | denotes | neutrophils | http://purl.org/sig/ont/fma/fma62860 |
| T108 | 1581-1592 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
| T109 | 1620-1628 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T110 | 1629-1641 | Body_part | denotes | fibroblastic | http://purl.org/sig/ont/fma/fma63877 |
| T111 | 1758-1766 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T112 | 1980-1988 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T60 | 142-147 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T61 | 521-526 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T62 | 787-791 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T63 | 1205-1209 | Body_part | denotes | head | http://purl.obolibrary.org/obo/UBERON_0000033 |
| T64 | 1435-1439 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T65 | 1440-1446 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T66 | 1758-1771 | Body_part | denotes | alveolar wall | http://purl.obolibrary.org/obo/UBERON_0004894 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 411 | 22-37 | Disease | denotes | alveolar damage | MESH:D055370 |
| 423 | 1168-1175 | Species | denotes | patient | Tax:9606 |
| 424 | 1342-1349 | Species | denotes | patient | Tax:9606 |
| 425 | 908-920 | Chemical | denotes | prednisolone | MESH:D011239 |
| 426 | 950-962 | Chemical | denotes | prednisolone | MESH:D011239 |
| 427 | 131-140 | Disease | denotes | hypoxemia | MESH:D000860 |
| 428 | 203-219 | Disease | denotes | pulmonary emboli | MESH:D011655 |
| 429 | 573-589 | Disease | denotes | pulmonary emboli | MESH:D011655 |
| 430 | 787-798 | Disease | denotes | lung injury | MESH:D055370 |
| 431 | 875-883 | Disease | denotes | fibrosis | MESH:D005355 |
| 432 | 1217-1225 | Disease | denotes | ischemia | MESH:D007511 |
| 433 | 1246-1257 | Disease | denotes | haemorrhage | MESH:D006470 |
| 435 | 1980-1995 | Disease | denotes | alveolar damage | MESH:D055370 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T155 | 792-798 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T156 | 1217-1225 | Disease | denotes | ischemia | http://purl.obolibrary.org/obo/MONDO_0005053 |
| T157 | 1870-1873 | Disease | denotes | PAS | http://purl.obolibrary.org/obo/MONDO_0004277 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T154 | 38-39 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T155 | 52-58 | http://purl.obolibrary.org/obo/UBERON_0003100 | denotes | female |
| T156 | 142-147 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T157 | 521-526 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T158 | 787-791 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T159 | 787-791 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T160 | 986-987 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T161 | 1205-1209 | http://purl.obolibrary.org/obo/UBERON_0000033 | denotes | head |
| T162 | 1205-1209 | http://www.ebi.ac.uk/efo/EFO_0000964 | denotes | head |
| T163 | 1435-1439 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T164 | 1435-1439 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T165 | 1603-1604 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T166 | 1629-1641 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblastic |
| T167 | 1738-1747 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membranes |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T96 | 392-395 | Chemical | denotes | BAL | http://purl.obolibrary.org/obo/CHEBI_64198 |
| T97 | 908-920 | Chemical | denotes | prednisolone | http://purl.obolibrary.org/obo/CHEBI_8378 |
| T98 | 950-962 | Chemical | denotes | prednisolone | http://purl.obolibrary.org/obo/CHEBI_8378 |
| T99 | 997-999 | Chemical | denotes | GM | http://purl.obolibrary.org/obo/CHEBI_74120|http://purl.obolibrary.org/obo/CHEBI_27680 |
| T101 | 1027-1030 | Chemical | denotes | BAL | http://purl.obolibrary.org/obo/CHEBI_64198 |
| T102 | 1870-1873 | Chemical | denotes | PAS | http://purl.obolibrary.org/obo/CHEBI_27565 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T45 | 14-37 | Phenotype | denotes | Diffuse alveolar damage | http://purl.obolibrary.org/obo/HP_0033006 |
| T46 | 131-140 | Phenotype | denotes | hypoxemia | http://purl.obolibrary.org/obo/HP_0012418 |
| T47 | 1972-1995 | Phenotype | denotes | diffuse alveolar damage | http://purl.obolibrary.org/obo/HP_0033006 |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T19 | 997-999 | GlycoEpitope | denotes | GM | http://www.glycoepitope.jp/epitopes/EP0510 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T143 | 0-37 | Sentence | denotes | 3.4 Case 3 – Diffuse alveolar damage |
| T144 | 38-141 | Sentence | denotes | A 58-year old female was admitted to the ICU and needed mechanical ventilation due to severe hypoxemia. |
| T145 | 142-349 | Sentence | denotes | Chest CT-angiography showed dubious unilateral sub-segmental pulmonary emboli and diffuse bilateral ground-glass opacities with anteroposterior gradient along with large dependant consolidations (Fig. 1-3A). |
| T146 | 350-520 | Sentence | denotes | On the 8th day of mechanical ventilation, BAL was performed and CT-scan was repeated because of deteriorating pulmonary condition with increasing inflammatory parameters. |
| T147 | 521-643 | Sentence | denotes | Chest CT-angiography showed bilateral sub-segmental pulmonary emboli, persistent ground-glass opacities and consolidation. |
| T148 | 644-811 | Sentence | denotes | Newly formed coarse cyst-like lesions in the middle and ventral regions (non-dependant regions) were noted, probably due to ventilator induced lung injury (Fig. 1-3B). |
| T149 | 812-933 | Sentence | denotes | Considering lack of respiratory improvement and progression of fibrosis on radiological imaging prednisolone was started. |
| T150 | 934-1037 | Sentence | denotes | After five days prednisolone was stopped because of a positive GM index of 3.4 from repeated BAL fluid. |
| T151 | 1038-1078 | Sentence | denotes | Fungal culture remained negative though. |
| T152 | 1079-1135 | Sentence | denotes | Her respiratory status stabilised but remained critical. |
| T153 | 1136-1258 | Sentence | denotes | After pausing the sedation, the patient remained unresponsive and CT head showed ischemia with small areas of haemorrhage. |
| T154 | 1259-1394 | Sentence | denotes | In light of her pour neurologic and respiratory prognosis, treatment was ended and patient expired after 26 days on ventilator support. |
| T155 | 1395-1494 | Sentence | denotes | In the core needle biopsy specimens the lung tissue largely preserved its preexisting architecture. |
| T156 | 1495-1647 | Sentence | denotes | Histologic findings included an inflammatory infiltrate consisting of neutrophils and lymphocytes, and only a sporadic intra-alveolar fibroblastic plug. |
| T157 | 1648-1782 | Sentence | denotes | The striking, distinctive feature of this case was the presence of thin, delicate hyaline membranes along the alveolar wall (Fig. 2C). |
| T158 | 1783-1831 | Sentence | denotes | Again, micro thrombi were observed in this case. |
| T159 | 1832-1882 | Sentence | denotes | No fungi could be demonstrated in the PAS-D stain. |
| T160 | 1883-1996 | Sentence | denotes | Together with the clinical characteristics, these histologic findings were suggestive of diffuse alveolar damage. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T344 | 196-264 | GO:0016020 | denotes | mental pulmonary emboli and diffuse bilateral ground-glass opacities |
| T345 | 514-715 | CL:0000771 | denotes | eters. Chest CT-angiography showed bilateral sub-segmental pulmonary emboli, persistent ground-glass opacities and consolidation. Newly formed coarse cyst-like lesions in the middle and ventral regions |
| T346 | 1269-1289 | NCBITaxon:4751 | denotes | f her pour neurologi |
| T301 | 22-30 | UBERON:0003215 | denotes | alveolar |
| T302 | 203-212 | UBERON:0002048 | denotes | pulmonary |
| T303 | 460-469 | UBERON:0002048 | denotes | pulmonary |
| T304 | 573-582 | UBERON:0002048 | denotes | pulmonary |
| T305 | 787-791 | UBERON:0002048 | denotes | lung |
| T306 | 832-843 | UBERON:0001004 | denotes | respiratory |
| T84520 | 908-920 | CHEBI:8378;CHEBI:8378 | denotes | prednisolone |
| T78423 | 950-962 | CHEBI:8378;CHEBI:8378 | denotes | prednisolone |
| T309 | 1031-1036 | UBERON:0006314 | denotes | fluid |
| T65961 | 1083-1094 | UBERON:0001004 | denotes | respiratory |
| T311 | 1205-1209 | UBERON:0000033 | denotes | head |
| T312 | 1280-1290 | UBERON:0001016 | denotes | neurologic |
| T66590 | 1295-1306 | UBERON:0001004 | denotes | respiratory |
| T314 | 1350-1357 | GO:0016265 | denotes | expired |
| T315 | 1435-1439 | UBERON:0002048 | denotes | lung |
| T316 | 1440-1446 | UBERON:0000479 | denotes | tissue |
| T317 | 1565-1576 | CL:0000775 | denotes | neutrophils |
| T40311 | 1581-1592 | CL:0000542 | denotes | lymphocytes |
| T61749 | 1620-1628 | UBERON:0003215 | denotes | alveolar |
| T93849 | 1629-1641 | CL:0000057 | denotes | fibroblastic |
| T97596 | 1642-1646 | UBERON:0010148 | denotes | plug |
| T49760 | 1758-1771 | UBERON:0004894 | denotes | alveolar wall |
| T73271 | 1796-1803 | UBERON:0010210 | denotes | thrombi |
| T36662 | 1835-1840 | NCBITaxon:4751 | denotes | fungi |
| T978 | 1980-1988 | UBERON:0003215 | denotes | alveolar |