PMC:7335494 / 95129-95912 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T685","span":{"begin":184,"end":190},"obj":"Body_part"},{"id":"T686","span":{"begin":732,"end":737},"obj":"Body_part"}],"attributes":[{"id":"A685","pred":"fma_id","subj":"T685","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A686","pred":"fma_id","subj":"T686","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T110","span":{"begin":732,"end":737},"obj":"Body_part"}],"attributes":[{"id":"A110","pred":"uberon_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T982","span":{"begin":73,"end":74},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T983","span":{"begin":184,"end":190},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T984","span":{"begin":334,"end":335},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T985","span":{"begin":452,"end":453},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T986","span":{"begin":454,"end":456},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T987","span":{"begin":488,"end":489},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T988","span":{"begin":732,"end":737},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T989","span":{"begin":732,"end":737},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1303","span":{"begin":97,"end":108},"obj":"Chemical"},{"id":"T1304","span":{"begin":120,"end":125},"obj":"Chemical"},{"id":"T1305","span":{"begin":191,"end":204},"obj":"Chemical"},{"id":"T1306","span":{"begin":267,"end":280},"obj":"Chemical"},{"id":"T1307","span":{"begin":269,"end":280},"obj":"Chemical"},{"id":"T1308","span":{"begin":321,"end":332},"obj":"Chemical"},{"id":"T1309","span":{"begin":365,"end":370},"obj":"Chemical"},{"id":"T1310","span":{"begin":375,"end":386},"obj":"Chemical"},{"id":"T1311","span":{"begin":432,"end":443},"obj":"Chemical"},{"id":"T1312","span":{"begin":527,"end":532},"obj":"Chemical"},{"id":"T1313","span":{"begin":537,"end":548},"obj":"Chemical"},{"id":"T1314","span":{"begin":665,"end":676},"obj":"Chemical"},{"id":"T1315","span":{"begin":713,"end":718},"obj":"Chemical"},{"id":"T1316","span":{"begin":738,"end":741},"obj":"Chemical"},{"id":"T1317","span":{"begin":746,"end":749},"obj":"Chemical"}],"attributes":[{"id":"A1303","pred":"chebi_id","subj":"T1303","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A1304","pred":"chebi_id","subj":"T1304","obj":"http://purl.obolibrary.org/obo/CHEBI_26208"},{"id":"A1305","pred":"chebi_id","subj":"T1305","obj":"http://purl.obolibrary.org/obo/CHEBI_17855"},{"id":"A1306","pred":"chebi_id","subj":"T1306","obj":"http://purl.obolibrary.org/obo/CHEBI_33023"},{"id":"A1307","pred":"chebi_id","subj":"T1307","obj":"http://purl.obolibrary.org/obo/CHEBI_138408"},{"id":"A1308","pred":"chebi_id","subj":"T1308","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A1309","pred":"chebi_id","subj":"T1309","obj":"http://purl.obolibrary.org/obo/CHEBI_26208"},{"id":"A71864","pred":"chebi_id","subj":"T1310","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A1311","pred":"chebi_id","subj":"T1311","obj":"http://purl.obolibrary.org/obo/CHEBI_16113"},{"id":"A1312","pred":"chebi_id","subj":"T1312","obj":"http://purl.obolibrary.org/obo/CHEBI_26208"},{"id":"A1313","pred":"chebi_id","subj":"T1313","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A1314","pred":"chebi_id","subj":"T1314","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A1315","pred":"chebi_id","subj":"T1315","obj":"http://purl.obolibrary.org/obo/CHEBI_26208"},{"id":"A1316","pred":"chebi_id","subj":"T1316","obj":"http://purl.obolibrary.org/obo/CHEBI_28364"},{"id":"A1317","pred":"chebi_id","subj":"T1317","obj":"http://purl.obolibrary.org/obo/CHEBI_16016"},{"id":"A1318","pred":"chebi_id","subj":"T1317","obj":"http://purl.obolibrary.org/obo/CHEBI_28125"},{"id":"A1319","pred":"chebi_id","subj":"T1317","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A1320","pred":"chebi_id","subj":"T1317","obj":"http://purl.obolibrary.org/obo/CHEBI_36005"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T278","span":{"begin":695,"end":705},"obj":"http://purl.obolibrary.org/obo/GO_0008152"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T565","span":{"begin":0,"end":205},"obj":"Sentence"},{"id":"T566","span":{"begin":206,"end":333},"obj":"Sentence"},{"id":"T567","span":{"begin":334,"end":572},"obj":"Sentence"},{"id":"T568","span":{"begin":573,"end":783},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T157","span":{"begin":52,"end":62},"obj":"Phenotype"},{"id":"T158","span":{"begin":229,"end":245},"obj":"Phenotype"}],"attributes":[{"id":"A157","pred":"hp_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/HP_0025502"},{"id":"A158","pred":"hp_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/HP_0025464"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"MyTest","denotations":[{"id":"32640331-24368433-30721056","span":{"begin":566,"end":570},"obj":"24368433"},{"id":"32640331-21068183-30721057","span":{"begin":777,"end":781},"obj":"21068183"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}

{"project":"2_test","denotations":[{"id":"32640331-24368433-30721056","span":{"begin":566,"end":570},"obj":"24368433"},{"id":"32640331-21068183-30721057","span":{"begin":777,"end":781},"obj":"21068183"}],"text":"In an 8-week randomized controlled dietary study on overweight patients, a combined diet of high polyphenols and marine PUFAs- diet showed beneficial, although non-additive effects on plasma triglycerides. Also, the reduction in oxidative stress (measured by urinary 8-isoprostane) was observed, probably as an effect of polyphenols. A negative interaction between PUFAs and polyphenols was observed for some variables (chylomicron cholesterol and apo B-48 in large VLDLs), which suggest a possible kinetic interaction between PUFAs and polyphenols (Annuzzi et al., 2014). This kinetic finding is also in line with some preclinical data that suggested that dietary polyphenols interact with the metabolism of n-3 PUFAs and increase blood EPA and DHA level (Toufektsian et al., 2011)."}