PMC:7335494 / 79838-85921 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7335494","sourcedb":"PMC","sourceid":"7335494","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7335494","text":"7.1 Cellular effects\nPolyphenols interfere with the inflammatory process in multiple pathways. For example, they alter the enzymatic processes involved in the proliferation and activation of B- and T-cells, as key components of the inflammatory pathway (by inhibiting tyrosine and serine-threonine protein kinases). Likewise, polyphenols blunt the synthesis of pro-inflammatory mediators such as cytokines, chemokines (IL-8, IL-6, TNF-α, VCAM-1 and ICAM-1), and angiogenic factors, NF-кB or iNOS. Further, an inhibitory effect on several pro-inflammatory enzymes was reported, such as COX-2, MAPK or protein kinase-C (PKC) (Alvarez-Suarez et al., 2017; Gasparrini et al., 2017; Hussain et al., 2016). Thus, studies performed on macrophages proved that resveratrol inhibited the IFN-γ-induced NO production and down-regulated the IFN-γ inducible genes. In this respect, resveratrol decreased STAT1 activation (an important transcription factor for IFN-γ-induced genes) and hindered JAK-2 activation (Chung et al., 2011).\nExperimental studies arguing the involvement of polyphenols in mitigating inflammation are either performed on cell line models, animal models or have direct clinical implications. In a study exposing human endothelial cells to the effect of Negroamaro and Primitivo extracts or pure compounds - stilbenes (trans-resveratrol, trans-piceid), hydroxycinnamic acids (p-coumaric, caffeic, and caftaric acids) flavonols (kaempferol, quercetin, myricetin) – before stimulation with lipopolysaccharide (LPS), an inhibition in the expression of adhesion molecules was demonstrated. The anti-inflammatory effect was sustained by a reduction of VCAM-1, ICAM-1, E-selectin, MCP-1 and macrophage colony-stimulating factor (M-CSF), ROS intracellular levels with a correlated attenuation of NF-κB and AP-1 activation. Trans-resveratrol also significantly reduced the endothelial expression and release of M-CSF. All tested compounds reduced the adhesion of monocytes to stimulated endothelial cells, this being a key element in the development of atherosclerosis (Calabriso et al., 2016). The treatment of CCD-18Co myofibroblasts cells with red wine extract reduced mRNA levels of ICAM-1, VCAM-1, NF-κB, and PECAM-1, induced by LPS the anti-inflammatory mechanism being dependent on miR-126 (Angel-Morales et al., 2012).\nAnother study tested the effects induced by a mixture of four main catechins found in green tea (epicatechin – EC, epigallocatechin – EGC, epigallocatechin gallate – EGCG, epicatechin gallate – GCG), as well as each one alone, on neutrophils isolated from healthy subjects. The catechin compounds induced anti-inflammatory effect (reduction of IL-1β and IL-6, TNF-α, HOCl synthesis and mieloperoxisase), together with the stimulation of antioxidant enzyme activities and Nrf2, along calcium release as well as increased phagocytic capacity, thus proving anti-inflammatory and immunomodulatory actions (Marinovic et al., 2015). In a separate study, EGCG reduced ICAM-1, NF-ĸB and IĸB expressions and reduced ROS levels upon TNF-α-induced inflammation in human retinal pigment epithelial cells. The results suggest the possible therapeutic involvement of EGCG in blocking TNF-α-mediated eye inflammation (Thichanpiang and Wongprasert, 2015). Moreover, in a study evaluating the effect of epicatechin and catechin on arachidonic acid-activated platelets and, respectively, on platelet-HUVEC interaction, the tested compounds induced a reduction of sICAM1, sVCAM1, and sE-selectin levels, as well as an increase of NO bioavailability, proving an anti-inflammatory effect and the ability to counteract endothelial dysfunction, but only when platelets were harvested from peripheral artery disease patients and not from healthy subjects (Carnevale et al., 2014).\nEllagic acid (EA) was tested for its ability to inhibit MIF-induced chemotactic migration of PBMCs, showing a failure to inhibit this response when PBMCs were stimulated with MIP-1α, but high specificity for MIF-induced effect (Sarkar et al., 2015). Chlorogenic acid exerted a dose depended anti-inflammatory effect showed by the reduction of IL-1β, TNF-α and IL-6 levels as well as the inhibition of NO synthesis and expression of COX-1 and iNOS in LPS-stimulated murine macrophages and microglial cells (Hwang et al., 2014).\nAn in vitro experiment evaluated the results induced by various flavonoids on the arachidonic acid release from rat neutrophils; kaempferol, luteolin, quercetin and amentoflavone reduced the inflammatory response and inhibited the activity of β-glucuronidase and lysozyme (Tordera et al., 1994). Furthermore, the positive outcome of Brassica oleracea extracts (water and methanol respectively) for CVD risk were examined; for this purpose, HUVECs were exposed to the extracts (24 h) and then to TNF-α stimulation. Exposure to the extracts from Brassica oleracea significantly reduced the TNF-α induced expression of E-selectin, ICAM-1 and VCAM-1 (Kuntz and Kunz, 2014). Another study demonstrated the capacity of extracts from Mango (Mangifera indica L.) to counteract TNF-α effects on HUVECs, through the inhibition of IL-6, IL-8, COX-2 and ICAM-1, while restoring the expression of eNOS usually down-regulated by TNF-α (Mura et al., 2015). Interestingly, in an animal model, for example, supplementation of standard chow with cacao phenolic compounds in apolipoprotein E-deficient mice, lead to an anti-inflammatory effect justified by a reduction of VCAM-1 and ICAM-1 expressions, a decrease of oxidative stress markers and a reduction of cholesterol accumulation in plaque compared to control (Natsume and Baba, 2014). Likewise, propolis (green, red or brown) treatment induced a reduction of MCP-1, VCAM, PECAM, FGF, PDGF, VEGF, MMP-9 and upregulated tissue inhibitor of metalloproteinases 1 (TIMP-1) in initial atherosclerotic lesions in LDL receptor gene knockout mice fed a diet rich in cholesterol for inducing atherosclerotic lesions; only red propolis upregulated heme oxygenase 1 (HO-1) and TIMP-1 in advanced atherosclerotic lesions (Daleprane et al., 2012).","divisions":[{"label":"label","span":{"begin":0,"end":3}},{"label":"title","span":{"begin":5,"end":21}},{"label":"p","span":{"begin":22,"end":1020}},{"label":"p","span":{"begin":1021,"end":2327}},{"label":"p","span":{"begin":2328,"end":3784}},{"label":"p","span":{"begin":3785,"end":4311}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T575","span":{"begin":201,"end":206},"obj":"Body_part"},{"id":"T576","span":{"begin":269,"end":277},"obj":"Body_part"},{"id":"T577","span":{"begin":282,"end":288},"obj":"Body_part"},{"id":"T578","span":{"begin":289,"end":298},"obj":"Body_part"},{"id":"T579","span":{"begin":299,"end":306},"obj":"Body_part"},{"id":"T580","span":{"begin":397,"end":406},"obj":"Body_part"},{"id":"T581","span":{"begin":408,"end":418},"obj":"Body_part"},{"id":"T582","span":{"begin":450,"end":454},"obj":"Body_part"},{"id":"T583","span":{"begin":601,"end":608},"obj":"Body_part"},{"id":"T584","span":{"begin":729,"end":740},"obj":"Body_part"},{"id":"T585","span":{"begin":1132,"end":1136},"obj":"Body_part"},{"id":"T586","span":{"begin":1228,"end":1245},"obj":"Body_part"},{"id":"T587","span":{"begin":1240,"end":1245},"obj":"Body_part"},{"id":"T588","span":{"begin":1497,"end":1515},"obj":"Body_part"},{"id":"T589","span":{"begin":1517,"end":1520},"obj":"Body_part"},{"id":"T590","span":{"begin":1664,"end":1668},"obj":"Body_part"},{"id":"T591","span":{"begin":1672,"end":1682},"obj":"Body_part"},{"id":"T592","span":{"begin":1694,"end":1704},"obj":"Body_part"},{"id":"T593","span":{"begin":1734,"end":1737},"obj":"Body_part"},{"id":"T594","span":{"begin":1914,"end":1917},"obj":"Body_part"},{"id":"T595","span":{"begin":1964,"end":1973},"obj":"Body_part"},{"id":"T596","span":{"begin":1988,"end":2005},"obj":"Body_part"},{"id":"T597","span":{"begin":2000,"end":2005},"obj":"Body_part"},{"id":"T598","span":{"begin":2122,"end":2136},"obj":"Body_part"},{"id":"T599","span":{"begin":2137,"end":2142},"obj":"Body_part"},{"id":"T600","span":{"begin":2173,"end":2177},"obj":"Body_part"},{"id":"T601","span":{"begin":2188,"end":2192},"obj":"Body_part"},{"id":"T602","span":{"begin":2235,"end":2238},"obj":"Body_part"},{"id":"T603","span":{"begin":2558,"end":2569},"obj":"Body_part"},{"id":"T604","span":{"begin":2672,"end":2676},"obj":"Body_part"},{"id":"T605","span":{"begin":2989,"end":2993},"obj":"Body_part"},{"id":"T606","span":{"begin":3087,"end":3119},"obj":"Body_part"},{"id":"T607","span":{"begin":3114,"end":3119},"obj":"Body_part"},{"id":"T608","span":{"begin":3213,"end":3216},"obj":"Body_part"},{"id":"T609","span":{"begin":3369,"end":3378},"obj":"Body_part"},{"id":"T610","span":{"begin":3401,"end":3409},"obj":"Body_part"},{"id":"T611","span":{"begin":3496,"end":3504},"obj":"Body_part"},{"id":"T612","span":{"begin":3664,"end":3673},"obj":"Body_part"},{"id":"T613","span":{"begin":3705,"end":3711},"obj":"Body_part"},{"id":"T614","span":{"begin":4128,"end":4132},"obj":"Body_part"},{"id":"T615","span":{"begin":4235,"end":4238},"obj":"Body_part"},{"id":"T616","span":{"begin":4257,"end":4268},"obj":"Body_part"},{"id":"T617","span":{"begin":4273,"end":4289},"obj":"Body_part"},{"id":"T618","span":{"begin":4284,"end":4289},"obj":"Body_part"},{"id":"T619","span":{"begin":4428,"end":4439},"obj":"Body_part"},{"id":"T620","span":{"begin":4928,"end":4938},"obj":"Body_part"},{"id":"T621","span":{"begin":4940,"end":4944},"obj":"Body_part"},{"id":"T622","span":{"begin":5154,"end":5158},"obj":"Body_part"},{"id":"T623","span":{"begin":5476,"end":5480},"obj":"Body_part"},{"id":"T624","span":{"begin":5768,"end":5774},"obj":"Body_part"},{"id":"T625","span":{"begin":5856,"end":5859},"obj":"Body_part"},{"id":"T626","span":{"begin":5869,"end":5873},"obj":"Body_part"}],"attributes":[{"id":"A575","pred":"fma_id","subj":"T575","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A576","pred":"fma_id","subj":"T576","obj":"http://purl.org/sig/ont/fma/fma82768"},{"id":"A577","pred":"fma_id","subj":"T577","obj":"http://purl.org/sig/ont/fma/fma82764"},{"id":"A578","pred":"fma_id","subj":"T578","obj":"http://purl.org/sig/ont/fma/fma82765"},{"id":"A579","pred":"fma_id","subj":"T579","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A580","pred":"fma_id","subj":"T580","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A581","pred":"fma_id","subj":"T581","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A582","pred":"fma_id","subj":"T582","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A583","pred":"fma_id","subj":"T583","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A584","pred":"fma_id","subj":"T584","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A585","pred":"fma_id","subj":"T585","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A586","pred":"fma_id","subj":"T586","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A587","pred":"fma_id","subj":"T587","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A588","pred":"fma_id","subj":"T588","obj":"http://purl.org/sig/ont/fma/fma82785"},{"id":"A589","pred":"fma_id","subj":"T589","obj":"http://purl.org/sig/ont/fma/fma82785"},{"id":"A590","pred":"fma_id","subj":"T590","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A591","pred":"fma_id","subj":"T591","obj":"http://purl.org/sig/ont/fma/fma62932"},{"id":"A592","pred":"fma_id","subj":"T592","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A593","pred":"fma_id","subj":"T593","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A594","pred":"fma_id","subj":"T594","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A595","pred":"fma_id","subj":"T595","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A596","pred":"fma_id","subj":"T596","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A597","pred":"fma_id","subj":"T597","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A598","pred":"fma_id","subj":"T598","obj":"http://purl.org/sig/ont/fma/fma0326458"},{"id":"A599","pred":"fma_id","subj":"T599","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A600","pred":"fma_id","subj":"T600","obj":"http://purl.org/sig/ont/fma/fma67122"},{"id":"A601","pred":"fma_id","subj":"T601","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A602","pred":"fma_id","subj":"T602","obj":"http://purl.org/sig/ont/fma/fma82785"},{"id":"A603","pred":"fma_id","subj":"T603","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A604","pred":"fma_id","subj":"T604","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A605","pred":"fma_id","subj":"T605","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A606","pred":"fma_id","subj":"T606","obj":"http://purl.org/sig/ont/fma/fma75802"},{"id":"A607","pred":"fma_id","subj":"T607","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A608","pred":"fma_id","subj":"T608","obj":"http://purl.org/sig/ont/fma/fma54448"},{"id":"A609","pred":"fma_id","subj":"T609","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A610","pred":"fma_id","subj":"T610","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A611","pred":"fma_id","subj":"T611","obj":"http://purl.org/sig/ont/fma/fma61795"},{"id":"A612","pred":"fma_id","subj":"T612","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A613","pred":"fma_id","subj":"T613","obj":"http://purl.org/sig/ont/fma/fma50720"},{"id":"A614","pred":"fma_id","subj":"T614","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A615","pred":"fma_id","subj":"T615","obj":"http://purl.org/sig/ont/fma/fma82785"},{"id":"A616","pred":"fma_id","subj":"T616","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A617","pred":"fma_id","subj":"T617","obj":"http://purl.org/sig/ont/fma/fma54539"},{"id":"A618","pred":"fma_id","subj":"T618","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A619","pred":"fma_id","subj":"T619","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A620","pred":"fma_id","subj":"T620","obj":"http://purl.org/sig/ont/fma/fma62932"},{"id":"A621","pred":"fma_id","subj":"T621","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A622","pred":"fma_id","subj":"T622","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A623","pred":"fma_id","subj":"T623","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A624","pred":"fma_id","subj":"T624","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A625","pred":"fma_id","subj":"T625","obj":"http://purl.org/sig/ont/fma/fma63170"},{"id":"A626","pred":"fma_id","subj":"T626","obj":"http://purl.org/sig/ont/fma/fma74402"},{"subj":"T575","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T576","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T577","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T578","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T579","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T580","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T581","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T582","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T583","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T584","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T585","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T586","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T587","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T588","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T589","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T590","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T591","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T592","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T593","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T594","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T595","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T596","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T597","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T598","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T599","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T600","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T601","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T602","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T603","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T604","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T605","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T606","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T607","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T608","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T609","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T610","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T611","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T612","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T613","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T614","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T615","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T616","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T617","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T618","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T619","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T620","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T621","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T622","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T623","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T624","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T625","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T626","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T98","span":{"begin":3213,"end":3216},"obj":"Body_part"},{"id":"T99","span":{"begin":3705,"end":3711},"obj":"Body_part"},{"id":"T100","span":{"begin":5768,"end":5774},"obj":"Body_part"}],"attributes":[{"id":"A98","pred":"uberon_id","subj":"T98","obj":"http://purl.obolibrary.org/obo/UBERON_0000970"},{"id":"A99","pred":"uberon_id","subj":"T99","obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"A100","pred":"uberon_id","subj":"T100","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"subj":"T98","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T232","span":{"begin":1095,"end":1107},"obj":"Disease"},{"id":"T233","span":{"begin":2054,"end":2069},"obj":"Disease"},{"id":"T234","span":{"begin":2462,"end":2465},"obj":"Disease"},{"id":"T235","span":{"begin":3065,"end":3077},"obj":"Disease"},{"id":"T236","span":{"begin":3217,"end":3229},"obj":"Disease"},{"id":"T237","span":{"begin":3694,"end":3719},"obj":"Disease"},{"id":"T238","span":{"begin":3705,"end":3719},"obj":"Disease"}],"attributes":[{"id":"A232","pred":"mondo_id","subj":"T232","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A233","pred":"mondo_id","subj":"T233","obj":"http://purl.obolibrary.org/obo/MONDO_0005311"},{"id":"A234","pred":"mondo_id","subj":"T234","obj":"http://purl.obolibrary.org/obo/MONDO_0001060"},{"id":"A235","pred":"mondo_id","subj":"T235","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A236","pred":"mondo_id","subj":"T236","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A237","pred":"mondo_id","subj":"T237","obj":"http://purl.obolibrary.org/obo/MONDO_0005386"},{"id":"A238","pred":"mondo_id","subj":"T238","obj":"http://purl.obolibrary.org/obo/MONDO_0000473"},{"subj":"T232","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T233","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T234","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T235","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T236","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T237","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T238","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T833","span":{"begin":178,"end":188},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T834","span":{"begin":192,"end":193},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T835","span":{"begin":199,"end":206},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T836","span":{"begin":420,"end":424},"obj":"http://purl.obolibrary.org/obo/CLO_0053704"},{"id":"T837","span":{"begin":487,"end":488},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T838","span":{"begin":846,"end":851},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T839","span":{"begin":898,"end":908},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T840","span":{"begin":962,"end":967},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T841","span":{"begin":988,"end":998},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T842","span":{"begin":1132,"end":1141},"obj":"http://purl.obolibrary.org/obo/CLO_0000031"},{"id":"T843","span":{"begin":1150,"end":1156},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"},{"id":"T844","span":{"begin":1205,"end":1206},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T845","span":{"begin":1222,"end":1227},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T846","span":{"begin":1228,"end":1245},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T847","span":{"begin":1641,"end":1642},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T848","span":{"begin":1770,"end":1771},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T849","span":{"begin":1802,"end":1810},"obj":"http://purl.obolibrary.org/obo/CL_0000613"},{"id":"T850","span":{"begin":1813,"end":1823},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T851","span":{"begin":1923,"end":1929},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T852","span":{"begin":1964,"end":1973},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T853","span":{"begin":1988,"end":2005},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T854","span":{"begin":2018,"end":2019},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T855","span":{"begin":2113,"end":2121},"obj":"http://purl.obolibrary.org/obo/CLO_0002309"},{"id":"T856","span":{"begin":2122,"end":2142},"obj":"http://purl.obolibrary.org/obo/CL_0000186"},{"id":"T857","span":{"begin":2208,"end":2209},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T858","span":{"begin":2342,"end":2348},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T859","span":{"begin":2372,"end":2373},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T860","span":{"begin":2439,"end":2441},"obj":"http://purl.obolibrary.org/obo/CLO_0002878"},{"id":"T861","span":{"begin":2784,"end":2794},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T862","span":{"begin":2848,"end":2858},"obj":"http://purl.obolibrary.org/obo/CL_0000234"},{"id":"T863","span":{"begin":2958,"end":2959},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T864","span":{"begin":3081,"end":3086},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T865","span":{"begin":3095,"end":3119},"obj":"http://purl.obolibrary.org/obo/CL_0000529"},{"id":"T866","span":{"begin":3213,"end":3216},"obj":"http://www.ebi.ac.uk/efo/EFO_0000827"},{"id":"T867","span":{"begin":3281,"end":3282},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T868","span":{"begin":3359,"end":3368},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T869","span":{"begin":3410,"end":3415},"obj":"http://purl.obolibrary.org/obo/CLO_0004307"},{"id":"T870","span":{"begin":3433,"end":3439},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T871","span":{"begin":3458,"end":3459},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T872","span":{"begin":3705,"end":3711},"obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"T873","span":{"begin":3705,"end":3711},"obj":"http://www.ebi.ac.uk/efo/EFO_0000814"},{"id":"T874","span":{"begin":3807,"end":3813},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T875","span":{"begin":3893,"end":3894},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T876","span":{"begin":4060,"end":4061},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T877","span":{"begin":4273,"end":4289},"obj":"http://purl.obolibrary.org/obo/CL_0000129"},{"id":"T878","span":{"begin":4543,"end":4551},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T879","span":{"begin":4752,"end":4758},"obj":"http://purl.obolibrary.org/obo/CLO_0004307"},{"id":"T880","span":{"begin":5098,"end":5104},"obj":"http://purl.obolibrary.org/obo/CLO_0004307"},{"id":"T881","span":{"begin":5138,"end":5142},"obj":"http://purl.obolibrary.org/obo/CLO_0053704"},{"id":"T882","span":{"begin":5275,"end":5281},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"},{"id":"T883","span":{"begin":5450,"end":5451},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T884","span":{"begin":5496,"end":5497},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T885","span":{"begin":5539,"end":5540},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T886","span":{"begin":5694,"end":5695},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T887","span":{"begin":5869,"end":5873},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T888","span":{"begin":5892,"end":5893},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T833","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T834","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T835","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T836","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T837","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T838","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T839","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T840","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T841","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T842","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T843","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T844","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T845","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T846","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T847","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T848","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T849","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T850","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T851","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T852","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T853","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T854","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T855","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T856","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T857","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T858","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T859","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T860","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T861","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T862","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T863","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T864","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T865","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T866","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T867","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T868","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T869","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T870","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T871","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T872","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T873","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T874","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T875","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T876","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T877","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T878","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T879","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T880","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T881","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T882","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T883","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T884","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T885","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T886","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T887","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T888","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1058","span":{"begin":269,"end":277},"obj":"Chemical"},{"id":"T1059","span":{"begin":282,"end":288},"obj":"Chemical"},{"id":"T1060","span":{"begin":289,"end":298},"obj":"Chemical"},{"id":"T1061","span":{"begin":299,"end":306},"obj":"Chemical"},{"id":"T1062","span":{"begin":327,"end":338},"obj":"Chemical"},{"id":"T1063","span":{"begin":420,"end":422},"obj":"Chemical"},{"id":"T1065","span":{"begin":426,"end":428},"obj":"Chemical"},{"id":"T1067","span":{"begin":483,"end":485},"obj":"Chemical"},{"id":"T1070","span":{"begin":601,"end":608},"obj":"Chemical"},{"id":"T1071","span":{"begin":753,"end":764},"obj":"Chemical"},{"id":"T1072","span":{"begin":870,"end":881},"obj":"Chemical"},{"id":"T1073","span":{"begin":1069,"end":1080},"obj":"Chemical"},{"id":"T1074","span":{"begin":1317,"end":1326},"obj":"Chemical"},{"id":"T1075","span":{"begin":1328,"end":1345},"obj":"Chemical"},{"id":"T1076","span":{"begin":1334,"end":1345},"obj":"Chemical"},{"id":"T1077","span":{"begin":1347,"end":1359},"obj":"Chemical"},{"id":"T1078","span":{"begin":1362,"end":1383},"obj":"Chemical"},{"id":"T1079","span":{"begin":1378,"end":1383},"obj":"Chemical"},{"id":"T1080","span":{"begin":1419,"end":1424},"obj":"Chemical"},{"id":"T1081","span":{"begin":1426,"end":1435},"obj":"Chemical"},{"id":"T1082","span":{"begin":1437,"end":1447},"obj":"Chemical"},{"id":"T1084","span":{"begin":1449,"end":1458},"obj":"Chemical"},{"id":"T1086","span":{"begin":1460,"end":1469},"obj":"Chemical"},{"id":"T1088","span":{"begin":1497,"end":1515},"obj":"Chemical"},{"id":"T1089","span":{"begin":1517,"end":1520},"obj":"Chemical"},{"id":"T1092","span":{"begin":1567,"end":1576},"obj":"Chemical"},{"id":"T1093","span":{"begin":1684,"end":1687},"obj":"Chemical"},{"id":"T1095","span":{"begin":1740,"end":1743},"obj":"Chemical"},{"id":"T1096","span":{"begin":1798,"end":1800},"obj":"Chemical"},{"id":"T1099","span":{"begin":1808,"end":1810},"obj":"Chemical"},{"id":"T1102","span":{"begin":1831,"end":1842},"obj":"Chemical"},{"id":"T1103","span":{"begin":2204,"end":2206},"obj":"Chemical"},{"id":"T1106","span":{"begin":2235,"end":2238},"obj":"Chemical"},{"id":"T1109","span":{"begin":2374,"end":2381},"obj":"Chemical"},{"id":"T1110","span":{"begin":2395,"end":2404},"obj":"Chemical"},{"id":"T1111","span":{"begin":2484,"end":2491},"obj":"Chemical"},{"id":"T1112","span":{"begin":2494,"end":2498},"obj":"Chemical"},{"id":"T1113","span":{"begin":2512,"end":2519},"obj":"Chemical"},{"id":"T1114","span":{"begin":2606,"end":2614},"obj":"Chemical"},{"id":"T1115","span":{"begin":2672,"end":2674},"obj":"Chemical"},{"id":"T1117","span":{"begin":2682,"end":2684},"obj":"Chemical"},{"id":"T1119","span":{"begin":2695,"end":2699},"obj":"Chemical"},{"id":"T1120","span":{"begin":2765,"end":2776},"obj":"Chemical"},{"id":"T1121","span":{"begin":2811,"end":2818},"obj":"Chemical"},{"id":"T1123","span":{"begin":2976,"end":2980},"obj":"Chemical"},{"id":"T1124","span":{"begin":2997,"end":2999},"obj":"Chemical"},{"id":"T1127","span":{"begin":3035,"end":3038},"obj":"Chemical"},{"id":"T1128","span":{"begin":3087,"end":3094},"obj":"Chemical"},{"id":"T1129","span":{"begin":3181,"end":3185},"obj":"Chemical"},{"id":"T1130","span":{"begin":3330,"end":3338},"obj":"Chemical"},{"id":"T1131","span":{"begin":3342,"end":3358},"obj":"Chemical"},{"id":"T1132","span":{"begin":3354,"end":3358},"obj":"Chemical"},{"id":"T1133","span":{"begin":3785,"end":3797},"obj":"Chemical"},{"id":"T1134","span":{"begin":3793,"end":3797},"obj":"Chemical"},{"id":"T1135","span":{"begin":3799,"end":3801},"obj":"Chemical"},{"id":"T1137","span":{"begin":4035,"end":4051},"obj":"Chemical"},{"id":"T1138","span":{"begin":4047,"end":4051},"obj":"Chemical"},{"id":"T1139","span":{"begin":4128,"end":4130},"obj":"Chemical"},{"id":"T1141","span":{"begin":4145,"end":4147},"obj":"Chemical"},{"id":"T1143","span":{"begin":4235,"end":4238},"obj":"Chemical"},{"id":"T1146","span":{"begin":4376,"end":4386},"obj":"Chemical"},{"id":"T1148","span":{"begin":4394,"end":4410},"obj":"Chemical"},{"id":"T1149","span":{"begin":4406,"end":4410},"obj":"Chemical"},{"id":"T1150","span":{"begin":4441,"end":4451},"obj":"Chemical"},{"id":"T1152","span":{"begin":4453,"end":4461},"obj":"Chemical"},{"id":"T1154","span":{"begin":4463,"end":4472},"obj":"Chemical"},{"id":"T1156","span":{"begin":4477,"end":4490},"obj":"Chemical"},{"id":"T1157","span":{"begin":4673,"end":4678},"obj":"Chemical"},{"id":"T1158","span":{"begin":4683,"end":4691},"obj":"Chemical"},{"id":"T1159","span":{"begin":5132,"end":5134},"obj":"Chemical"},{"id":"T1161","span":{"begin":5138,"end":5140},"obj":"Chemical"},{"id":"T1163","span":{"begin":5368,"end":5382},"obj":"Chemical"},{"id":"T1164","span":{"begin":5554,"end":5565},"obj":"Chemical"},{"id":"T1165","span":{"begin":5709,"end":5712},"obj":"Chemical"},{"id":"T1167","span":{"begin":5746,"end":5749},"obj":"Chemical"},{"id":"T1169","span":{"begin":5775,"end":5784},"obj":"Chemical"},{"id":"T1170","span":{"begin":5856,"end":5859},"obj":"Chemical"},{"id":"T1171","span":{"begin":5907,"end":5918},"obj":"Chemical"},{"id":"T1172","span":{"begin":5987,"end":5991},"obj":"Chemical"}],"attributes":[{"id":"A1058","pred":"chebi_id","subj":"T1058","obj":"http://purl.obolibrary.org/obo/CHEBI_18186"},{"id":"A1059","pred":"chebi_id","subj":"T1059","obj":"http://purl.obolibrary.org/obo/CHEBI_17822"},{"id":"A1060","pred":"chebi_id","subj":"T1060","obj":"http://purl.obolibrary.org/obo/CHEBI_26986"},{"id":"A1061","pred":"chebi_id","subj":"T1061","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A1062","pred":"chebi_id","subj":"T1062","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A1063","pred":"chebi_id","subj":"T1063","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1064","pred":"chebi_id","subj":"T1063","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1065","pred":"chebi_id","subj":"T1065","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1066","pred":"chebi_id","subj":"T1065","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1067","pred":"chebi_id","subj":"T1067","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A1068","pred":"chebi_id","subj":"T1067","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A1069","pred":"chebi_id","subj":"T1067","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A1070","pred":"chebi_id","subj":"T1070","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A1071","pred":"chebi_id","subj":"T1071","obj":"http://purl.obolibrary.org/obo/CHEBI_27881"},{"id":"A1072","pred":"chebi_id","subj":"T1072","obj":"http://purl.obolibrary.org/obo/CHEBI_27881"},{"id":"A1073","pred":"chebi_id","subj":"T1073","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A1074","pred":"chebi_id","subj":"T1074","obj":"http://purl.obolibrary.org/obo/CHEBI_26776"},{"id":"A1075","pred":"chebi_id","subj":"T1075","obj":"http://purl.obolibrary.org/obo/CHEBI_45713"},{"id":"A1076","pred":"chebi_id","subj":"T1076","obj":"http://purl.obolibrary.org/obo/CHEBI_27881"},{"id":"A1077","pred":"chebi_id","subj":"T1077","obj":"http://purl.obolibrary.org/obo/CHEBI_8198"},{"id":"A1078","pred":"chebi_id","subj":"T1078","obj":"http://purl.obolibrary.org/obo/CHEBI_24689"},{"id":"A1079","pred":"chebi_id","subj":"T1079","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A1080","pred":"chebi_id","subj":"T1080","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A1081","pred":"chebi_id","subj":"T1081","obj":"http://purl.obolibrary.org/obo/CHEBI_28802"},{"id":"A1082","pred":"chebi_id","subj":"T1082","obj":"http://purl.obolibrary.org/obo/CHEBI_28499"},{"id":"A1083","pred":"chebi_id","subj":"T1082","obj":"http://purl.obolibrary.org/obo/CHEBI_58573"},{"id":"A1084","pred":"chebi_id","subj":"T1084","obj":"http://purl.obolibrary.org/obo/CHEBI_16243"},{"id":"A1085","pred":"chebi_id","subj":"T1084","obj":"http://purl.obolibrary.org/obo/CHEBI_57694"},{"id":"A1086","pred":"chebi_id","subj":"T1086","obj":"http://purl.obolibrary.org/obo/CHEBI_18152"},{"id":"A1087","pred":"chebi_id","subj":"T1086","obj":"http://purl.obolibrary.org/obo/CHEBI_58395"},{"id":"A1088","pred":"chebi_id","subj":"T1088","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A1089","pred":"chebi_id","subj":"T1089","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A1090","pred":"chebi_id","subj":"T1089","obj":"http://purl.obolibrary.org/obo/CHEBI_52603"},{"id":"A1091","pred":"chebi_id","subj":"T1089","obj":"http://purl.obolibrary.org/obo/CHEBI_89981"},{"id":"A1092","pred":"chebi_id","subj":"T1092","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A1093","pred":"chebi_id","subj":"T1093","obj":"http://purl.obolibrary.org/obo/CHEBI_132592"},{"id":"A1094","pred":"chebi_id","subj":"T1093","obj":"http://purl.obolibrary.org/obo/CHEBI_50099"},{"id":"A1095","pred":"chebi_id","subj":"T1095","obj":"http://purl.obolibrary.org/obo/CHEBI_26523"},{"id":"A1096","pred":"chebi_id","subj":"T1096","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A1097","pred":"chebi_id","subj":"T1096","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A1098","pred":"chebi_id","subj":"T1096","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A1099","pred":"chebi_id","subj":"T1099","obj":"http://purl.obolibrary.org/obo/CHEBI_28971"},{"id":"A1100","pred":"chebi_id","subj":"T1099","obj":"http://purl.obolibrary.org/obo/CHEBI_73393"},{"id":"A1101","pred":"chebi_id","subj":"T1099","obj":"http://purl.obolibrary.org/obo/CHEBI_81686"},{"id":"A1102","pred":"chebi_id","subj":"T1102","obj":"http://purl.obolibrary.org/obo/CHEBI_27881"},{"id":"A1103","pred":"chebi_id","subj":"T1103","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A1104","pred":"chebi_id","subj":"T1103","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A1105","pred":"chebi_id","subj":"T1103","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A1106","pred":"chebi_id","subj":"T1106","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A1107","pred":"chebi_id","subj":"T1106","obj":"http://purl.obolibrary.org/obo/CHEBI_52603"},{"id":"A1108","pred":"chebi_id","subj":"T1106","obj":"http://purl.obolibrary.org/obo/CHEBI_89981"},{"id":"A1109","pred":"chebi_id","subj":"T1109","obj":"http://purl.obolibrary.org/obo/CHEBI_60004"},{"id":"A1110","pred":"chebi_id","subj":"T1110","obj":"http://purl.obolibrary.org/obo/CHEBI_23053"},{"id":"A1111","pred":"chebi_id","subj":"T1111","obj":"http://purl.obolibrary.org/obo/CHEBI_16918"},{"id":"A1112","pred":"chebi_id","subj":"T1112","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A1113","pred":"chebi_id","subj":"T1113","obj":"http://purl.obolibrary.org/obo/CHEBI_16918"},{"id":"A1114","pred":"chebi_id","subj":"T1114","obj":"http://purl.obolibrary.org/obo/CHEBI_23053"},{"id":"A1115","pred":"chebi_id","subj":"T1115","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1116","pred":"chebi_id","subj":"T1115","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1117","pred":"chebi_id","subj":"T1117","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1118","pred":"chebi_id","subj":"T1117","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1119","pred":"chebi_id","subj":"T1119","obj":"http://purl.obolibrary.org/obo/CHEBI_24757"},{"id":"A1120","pred":"chebi_id","subj":"T1120","obj":"http://purl.obolibrary.org/obo/CHEBI_22586"},{"id":"A1121","pred":"chebi_id","subj":"T1121","obj":"http://purl.obolibrary.org/obo/CHEBI_22984"},{"id":"A1122","pred":"chebi_id","subj":"T1121","obj":"http://purl.obolibrary.org/obo/CHEBI_29320"},{"id":"A1123","pred":"chebi_id","subj":"T1123","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A1124","pred":"chebi_id","subj":"T1124","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A1125","pred":"chebi_id","subj":"T1124","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A1126","pred":"chebi_id","subj":"T1124","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A1127","pred":"chebi_id","subj":"T1127","obj":"http://purl.obolibrary.org/obo/CHEBI_26523"},{"id":"A1128","pred":"chebi_id","subj":"T1128","obj":"http://purl.obolibrary.org/obo/CHEBI_15035"},{"id":"A1129","pred":"chebi_id","subj":"T1129","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A1130","pred":"chebi_id","subj":"T1130","obj":"http://purl.obolibrary.org/obo/CHEBI_23053"},{"id":"A1131","pred":"chebi_id","subj":"T1131","obj":"http://purl.obolibrary.org/obo/CHEBI_15843"},{"id":"A1132","pred":"chebi_id","subj":"T1132","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A1133","pred":"chebi_id","subj":"T1133","obj":"http://purl.obolibrary.org/obo/CHEBI_4775"},{"id":"A1134","pred":"chebi_id","subj":"T1134","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A1135","pred":"chebi_id","subj":"T1135","obj":"http://purl.obolibrary.org/obo/CHEBI_73849"},{"id":"A1136","pred":"chebi_id","subj":"T1135","obj":"http://purl.obolibrary.org/obo/CHEBI_4775"},{"id":"A1137","pred":"chebi_id","subj":"T1137","obj":"http://purl.obolibrary.org/obo/CHEBI_16112"},{"id":"A1138","pred":"chebi_id","subj":"T1138","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A1139","pred":"chebi_id","subj":"T1139","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1140","pred":"chebi_id","subj":"T1139","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1141","pred":"chebi_id","subj":"T1141","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1142","pred":"chebi_id","subj":"T1141","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1143","pred":"chebi_id","subj":"T1143","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A1144","pred":"chebi_id","subj":"T1143","obj":"http://purl.obolibrary.org/obo/CHEBI_52603"},{"id":"A1145","pred":"chebi_id","subj":"T1143","obj":"http://purl.obolibrary.org/obo/CHEBI_89981"},{"id":"A1146","pred":"chebi_id","subj":"T1146","obj":"http://purl.obolibrary.org/obo/CHEBI_47916"},{"id":"A1147","pred":"chebi_id","subj":"T1146","obj":"http://purl.obolibrary.org/obo/CHEBI_72544"},{"id":"A1148","pred":"chebi_id","subj":"T1148","obj":"http://purl.obolibrary.org/obo/CHEBI_15843"},{"id":"A1149","pred":"chebi_id","subj":"T1149","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A1150","pred":"chebi_id","subj":"T1150","obj":"http://purl.obolibrary.org/obo/CHEBI_28499"},{"id":"A1151","pred":"chebi_id","subj":"T1150","obj":"http://purl.obolibrary.org/obo/CHEBI_58573"},{"id":"A1152","pred":"chebi_id","subj":"T1152","obj":"http://purl.obolibrary.org/obo/CHEBI_15864"},{"id":"A1153","pred":"chebi_id","subj":"T1152","obj":"http://purl.obolibrary.org/obo/CHEBI_57545"},{"id":"A1154","pred":"chebi_id","subj":"T1154","obj":"http://purl.obolibrary.org/obo/CHEBI_16243"},{"id":"A1155","pred":"chebi_id","subj":"T1154","obj":"http://purl.obolibrary.org/obo/CHEBI_57694"},{"id":"A1156","pred":"chebi_id","subj":"T1156","obj":"http://purl.obolibrary.org/obo/CHEBI_2631"},{"id":"A1157","pred":"chebi_id","subj":"T1157","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A1158","pred":"chebi_id","subj":"T1158","obj":"http://purl.obolibrary.org/obo/CHEBI_17790"},{"id":"A1159","pred":"chebi_id","subj":"T1159","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1160","pred":"chebi_id","subj":"T1159","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1161","pred":"chebi_id","subj":"T1161","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A1162","pred":"chebi_id","subj":"T1161","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A1163","pred":"chebi_id","subj":"T1163","obj":"http://purl.obolibrary.org/obo/CHEBI_39015"},{"id":"A1164","pred":"chebi_id","subj":"T1164","obj":"http://purl.obolibrary.org/obo/CHEBI_16113"},{"id":"A1165","pred":"chebi_id","subj":"T1165","obj":"http://purl.obolibrary.org/obo/CHEBI_132592"},{"id":"A1166","pred":"chebi_id","subj":"T1165","obj":"http://purl.obolibrary.org/obo/CHEBI_50099"},{"id":"A1167","pred":"chebi_id","subj":"T1167","obj":"http://purl.obolibrary.org/obo/CHEBI_340824"},{"id":"A1168","pred":"chebi_id","subj":"T1167","obj":"http://purl.obolibrary.org/obo/CHEBI_59761"},{"id":"A1169","pred":"chebi_id","subj":"T1169","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A1170","pred":"chebi_id","subj":"T1170","obj":"http://purl.obolibrary.org/obo/CHEBI_39026"},{"id":"A1171","pred":"chebi_id","subj":"T1171","obj":"http://purl.obolibrary.org/obo/CHEBI_16113"},{"id":"A1172","pred":"chebi_id","subj":"T1172","obj":"http://purl.obolibrary.org/obo/CHEBI_26355"},{"id":"A1173","pred":"chebi_id","subj":"T1172","obj":"http://purl.obolibrary.org/obo/CHEBI_30413"},{"subj":"T1058","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1059","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1060","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1061","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1062","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1063","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1065","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1067","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1070","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1071","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1072","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1073","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1074","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1075","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1076","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1077","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1078","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1079","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1080","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1081","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1082","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1084","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1086","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1088","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1089","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1092","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1093","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1095","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1096","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1099","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1102","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1103","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1106","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1109","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1110","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1111","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1112","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1113","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1114","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1115","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1117","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1119","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1120","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1121","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1123","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1124","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1127","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1128","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1129","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1130","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1131","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1132","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1133","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1134","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1135","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1137","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1138","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1139","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1141","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1143","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1146","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1148","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1149","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1150","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1152","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1154","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1156","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1157","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1158","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1159","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1161","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1163","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1164","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1165","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1167","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1169","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1170","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1171","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T1172","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T254","span":{"begin":349,"end":358},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T255","span":{"begin":593,"end":597},"obj":"http://purl.obolibrary.org/obo/GO_0004707"},{"id":"T256","span":{"begin":616,"end":623},"obj":"http://purl.obolibrary.org/obo/GO_0004697"},{"id":"T257","span":{"begin":923,"end":943},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T258","span":{"begin":923,"end":936},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T259","span":{"begin":1095,"end":1107},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T260","span":{"begin":2700,"end":2709},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T261","span":{"begin":3065,"end":3077},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T262","span":{"begin":3217,"end":3229},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T263","span":{"begin":4189,"end":4198},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T264","span":{"begin":4503,"end":4524},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T265","span":{"begin":5368,"end":5382},"obj":"http://purl.obolibrary.org/obo/GO_0005319"},{"id":"T266","span":{"begin":5856,"end":5868},"obj":"http://purl.obolibrary.org/obo/GO_0005041"}],"attributes":[{"subj":"T254","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T255","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T256","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T257","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T258","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T259","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T260","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T261","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T262","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T263","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T264","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T265","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T266","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T486","span":{"begin":0,"end":21},"obj":"Sentence"},{"id":"T487","span":{"begin":22,"end":95},"obj":"Sentence"},{"id":"T488","span":{"begin":96,"end":316},"obj":"Sentence"},{"id":"T489","span":{"begin":317,"end":497},"obj":"Sentence"},{"id":"T490","span":{"begin":498,"end":701},"obj":"Sentence"},{"id":"T491","span":{"begin":702,"end":852},"obj":"Sentence"},{"id":"T492","span":{"begin":853,"end":1020},"obj":"Sentence"},{"id":"T493","span":{"begin":1021,"end":1201},"obj":"Sentence"},{"id":"T494","span":{"begin":1202,"end":1594},"obj":"Sentence"},{"id":"T495","span":{"begin":1595,"end":1824},"obj":"Sentence"},{"id":"T496","span":{"begin":1825,"end":1918},"obj":"Sentence"},{"id":"T497","span":{"begin":1919,"end":2095},"obj":"Sentence"},{"id":"T498","span":{"begin":2096,"end":2327},"obj":"Sentence"},{"id":"T499","span":{"begin":2328,"end":2601},"obj":"Sentence"},{"id":"T500","span":{"begin":2602,"end":2954},"obj":"Sentence"},{"id":"T501","span":{"begin":2955,"end":3120},"obj":"Sentence"},{"id":"T502","span":{"begin":3121,"end":3267},"obj":"Sentence"},{"id":"T503","span":{"begin":3268,"end":3784},"obj":"Sentence"},{"id":"T504","span":{"begin":3785,"end":4034},"obj":"Sentence"},{"id":"T505","span":{"begin":4035,"end":4311},"obj":"Sentence"},{"id":"T506","span":{"begin":4312,"end":4607},"obj":"Sentence"},{"id":"T507","span":{"begin":4608,"end":4825},"obj":"Sentence"},{"id":"T508","span":{"begin":4826,"end":4981},"obj":"Sentence"},{"id":"T509","span":{"begin":4982,"end":5253},"obj":"Sentence"},{"id":"T510","span":{"begin":5254,"end":5634},"obj":"Sentence"},{"id":"T511","span":{"begin":5635,"end":6083},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T486","pred":"source","obj":"LitCovid-sentences"},{"subj":"T487","pred":"source","obj":"LitCovid-sentences"},{"subj":"T488","pred":"source","obj":"LitCovid-sentences"},{"subj":"T489","pred":"source","obj":"LitCovid-sentences"},{"subj":"T490","pred":"source","obj":"LitCovid-sentences"},{"subj":"T491","pred":"source","obj":"LitCovid-sentences"},{"subj":"T492","pred":"source","obj":"LitCovid-sentences"},{"subj":"T493","pred":"source","obj":"LitCovid-sentences"},{"subj":"T494","pred":"source","obj":"LitCovid-sentences"},{"subj":"T495","pred":"source","obj":"LitCovid-sentences"},{"subj":"T496","pred":"source","obj":"LitCovid-sentences"},{"subj":"T497","pred":"source","obj":"LitCovid-sentences"},{"subj":"T498","pred":"source","obj":"LitCovid-sentences"},{"subj":"T499","pred":"source","obj":"LitCovid-sentences"},{"subj":"T500","pred":"source","obj":"LitCovid-sentences"},{"subj":"T501","pred":"source","obj":"LitCovid-sentences"},{"subj":"T502","pred":"source","obj":"LitCovid-sentences"},{"subj":"T503","pred":"source","obj":"LitCovid-sentences"},{"subj":"T504","pred":"source","obj":"LitCovid-sentences"},{"subj":"T505","pred":"source","obj":"LitCovid-sentences"},{"subj":"T506","pred":"source","obj":"LitCovid-sentences"},{"subj":"T507","pred":"source","obj":"LitCovid-sentences"},{"subj":"T508","pred":"source","obj":"LitCovid-sentences"},{"subj":"T509","pred":"source","obj":"LitCovid-sentences"},{"subj":"T510","pred":"source","obj":"LitCovid-sentences"},{"subj":"T511","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T135","span":{"begin":2054,"end":2069},"obj":"Phenotype"},{"id":"T136","span":{"begin":3625,"end":3648},"obj":"Phenotype"},{"id":"T137","span":{"begin":3694,"end":3719},"obj":"Phenotype"},{"id":"T138","span":{"begin":5510,"end":5526},"obj":"Phenotype"},{"id":"T139","span":{"begin":5829,"end":5852},"obj":"Phenotype"},{"id":"T140","span":{"begin":5932,"end":5955},"obj":"Phenotype"},{"id":"T141","span":{"begin":6034,"end":6057},"obj":"Phenotype"}],"attributes":[{"id":"A135","pred":"hp_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/HP_0002621"},{"id":"A136","pred":"hp_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/HP_0032654"},{"id":"A137","pred":"hp_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/HP_0004950"},{"id":"A138","pred":"hp_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/HP_0025464"},{"id":"A139","pred":"hp_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/HP_0031678"},{"id":"A140","pred":"hp_id","subj":"T140","obj":"http://purl.obolibrary.org/obo/HP_0031678"},{"id":"A141","pred":"hp_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/HP_0031678"},{"subj":"T135","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T136","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T137","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T138","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T139","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T140","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T141","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"MyTest","denotations":[{"id":"32640331-28137607-30721021","span":{"begin":648,"end":652},"obj":"28137607"},{"id":"32640331-28130090-30721022","span":{"begin":673,"end":677},"obj":"28130090"},{"id":"32640331-21189227-30721023","span":{"begin":1014,"end":1018},"obj":"21189227"},{"id":"32640331-25724173-30721024","span":{"begin":2089,"end":2093},"obj":"25724173"},{"id":"32640331-22572890-30721025","span":{"begin":2321,"end":2325},"obj":"22572890"},{"id":"32640331-25644976-30721026","span":{"begin":3261,"end":3265},"obj":"25644976"},{"id":"32640331-25929447-30721027","span":{"begin":4028,"end":4032},"obj":"25929447"},{"id":"32640331-24127072-30721028","span":{"begin":4305,"end":4309},"obj":"24127072"},{"id":"32640331-8018254-30721029","span":{"begin":4601,"end":4605},"obj":"8018254"},{"id":"32640331-24683602-30721030","span":{"begin":4975,"end":4979},"obj":"24683602"},{"id":"32640331-25589236-30721031","span":{"begin":5247,"end":5251},"obj":"25589236"},{"id":"32640331-24374929-30721032","span":{"begin":5628,"end":5632},"obj":"24374929"},{"id":"32640331-21764281-30721033","span":{"begin":6077,"end":6081},"obj":"21764281"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"32640331-28137607-30721021","pred":"source","obj":"MyTest"},{"subj":"32640331-28130090-30721022","pred":"source","obj":"MyTest"},{"subj":"32640331-21189227-30721023","pred":"source","obj":"MyTest"},{"subj":"32640331-25724173-30721024","pred":"source","obj":"MyTest"},{"subj":"32640331-22572890-30721025","pred":"source","obj":"MyTest"},{"subj":"32640331-25644976-30721026","pred":"source","obj":"MyTest"},{"subj":"32640331-25929447-30721027","pred":"source","obj":"MyTest"},{"subj":"32640331-24127072-30721028","pred":"source","obj":"MyTest"},{"subj":"32640331-8018254-30721029","pred":"source","obj":"MyTest"},{"subj":"32640331-24683602-30721030","pred":"source","obj":"MyTest"},{"subj":"32640331-25589236-30721031","pred":"source","obj":"MyTest"},{"subj":"32640331-24374929-30721032","pred":"source","obj":"MyTest"},{"subj":"32640331-21764281-30721033","pred":"source","obj":"MyTest"}]},{"project":"2_test","denotations":[{"id":"32640331-28137607-30721021","span":{"begin":648,"end":652},"obj":"28137607"},{"id":"32640331-28130090-30721022","span":{"begin":673,"end":677},"obj":"28130090"},{"id":"32640331-21189227-30721023","span":{"begin":1014,"end":1018},"obj":"21189227"},{"id":"32640331-25724173-30721024","span":{"begin":2089,"end":2093},"obj":"25724173"},{"id":"32640331-22572890-30721025","span":{"begin":2321,"end":2325},"obj":"22572890"},{"id":"32640331-25644976-30721026","span":{"begin":3261,"end":3265},"obj":"25644976"},{"id":"32640331-25929447-30721027","span":{"begin":4028,"end":4032},"obj":"25929447"},{"id":"32640331-24127072-30721028","span":{"begin":4305,"end":4309},"obj":"24127072"},{"id":"32640331-8018254-30721029","span":{"begin":4601,"end":4605},"obj":"8018254"},{"id":"32640331-24683602-30721030","span":{"begin":4975,"end":4979},"obj":"24683602"},{"id":"32640331-25589236-30721031","span":{"begin":5247,"end":5251},"obj":"25589236"},{"id":"32640331-24374929-30721032","span":{"begin":5628,"end":5632},"obj":"24374929"},{"id":"32640331-21764281-30721033","span":{"begin":6077,"end":6081},"obj":"21764281"}],"attributes":[{"subj":"32640331-28137607-30721021","pred":"source","obj":"2_test"},{"subj":"32640331-28130090-30721022","pred":"source","obj":"2_test"},{"subj":"32640331-21189227-30721023","pred":"source","obj":"2_test"},{"subj":"32640331-25724173-30721024","pred":"source","obj":"2_test"},{"subj":"32640331-22572890-30721025","pred":"source","obj":"2_test"},{"subj":"32640331-25644976-30721026","pred":"source","obj":"2_test"},{"subj":"32640331-25929447-30721027","pred":"source","obj":"2_test"},{"subj":"32640331-24127072-30721028","pred":"source","obj":"2_test"},{"subj":"32640331-8018254-30721029","pred":"source","obj":"2_test"},{"subj":"32640331-24683602-30721030","pred":"source","obj":"2_test"},{"subj":"32640331-25589236-30721031","pred":"source","obj":"2_test"},{"subj":"32640331-24374929-30721032","pred":"source","obj":"2_test"},{"subj":"32640331-21764281-30721033","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#a7ec93","default":true},{"id":"LitCovid-PD-UBERON","color":"#ec93c1"},{"id":"LitCovid-PD-MONDO","color":"#93dbec"},{"id":"LitCovid-PD-CLO","color":"#ece393"},{"id":"LitCovid-PD-CHEBI","color":"#c993ec"},{"id":"LitCovid-PD-GO-BP","color":"#93ecaf"},{"id":"LitCovid-sentences","color":"#ec9493"},{"id":"LitCovid-PD-HP","color":"#93abec"},{"id":"MyTest","color":"#c5ec93"},{"id":"2_test","color":"#ec93df"}]}]}}