PMC:7335494 / 78734-79836
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T568 | 366-369 | Body_part | denotes | LDL | http://purl.org/sig/ont/fma/fma63170 |
| T569 | 671-675 | Body_part | denotes | ICAM | http://purl.org/sig/ont/fma/fma67857 |
| T570 | 679-689 | Body_part | denotes | E-selectin | http://purl.org/sig/ont/fma/fma62932 |
| T571 | 716-725 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T572 | 733-744 | Body_part | denotes | endothelium | http://purl.org/sig/ont/fma/fma63916 |
| T573 | 810-818 | Body_part | denotes | monocyte | http://purl.org/sig/ont/fma/fma62864 |
| T574 | 914-926 | Body_part | denotes | interleukins | http://purl.org/sig/ont/fma/fma86578 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T97 | 733-744 | Body_part | denotes | endothelium | http://purl.obolibrary.org/obo/UBERON_0001986 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T229 | 117-135 | Disease | denotes | metabolic syndrome | http://purl.obolibrary.org/obo/MONDO_0004955 |
| T230 | 280-295 | Disease | denotes | atherosclerosis | http://purl.obolibrary.org/obo/MONDO_0005311 |
| T231 | 299-311 | Disease | denotes | dyslipidemia | http://purl.obolibrary.org/obo/MONDO_0002525 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T823 | 244-245 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T824 | 411-421 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T825 | 555-556 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T826 | 716-725 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T827 | 733-744 | http://purl.obolibrary.org/obo/UBERON_0001986 | denotes | endothelium |
| T828 | 797-798 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T829 | 810-818 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocyte |
| T830 | 895-896 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T831 | 937-941 | http://purl.obolibrary.org/obo/CLO_0053704 | denotes | IL-8 |
| T832 | 1014-1018 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1041 | 20-38 | Chemical | denotes | dietary components | http://purl.obolibrary.org/obo/CHEBI_78295 |
| T1042 | 343-346 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
| T1043 | 366-369 | Chemical | denotes | LDL | http://purl.obolibrary.org/obo/CHEBI_39026 |
| T1044 | 511-514 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
| T1045 | 536-545 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T1046 | 652-661 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T1047 | 847-856 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T1048 | 884-887 | Chemical | denotes | MCP | http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099 |
| T1050 | 892-894 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
| T1053 | 914-926 | Chemical | denotes | interleukins | http://purl.obolibrary.org/obo/CHEBI_52998 |
| T1054 | 928-930 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T1056 | 937-939 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T251 | 343-356 | http://purl.obolibrary.org/obo/GO_1903409 | denotes | ROS formation |
| T252 | 347-356 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T253 | 819-829 | http://purl.obolibrary.org/obo/GO_0050904 | denotes | diapedesis |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T481 | 0-230 | Sentence | denotes | Polyphenols are key dietary components extensively studied for their involvement in preventing CVD, comorbidities of metabolic syndrome, malignancies, etc, all these diseases having an important etiological inflammatory component. |
| T482 | 231-472 | Sentence | denotes | For example, a central stage in the expansion of atherosclerosis is dyslipidemia, which together with increased ROS formation leads to LDL oxidation, which was correlated with the activation of pro-inflammatory pathways in the vascular wall. |
| T483 | 473-614 | Sentence | denotes | Likewise, it is well established that ROS and pro-inflammatory molecules generate a microenvironment predisposing to endothelial dysfunction. |
| T484 | 615-793 | Sentence | denotes | The increased expression of adhesion molecules (VCAM-1, ICAM-1, E-selectin) favours the adherence of monocytes to the endothelium and their infiltration within the vascular wall. |
| T485 | 794-1102 | Sentence | denotes | As a result, of monocyte diapedesis pro-inflammatory molecules are released (TNF-α, IFNγ, MCP-1), NFκB is up-regulated, interleukins (IL-6 and IL-8) and metalloproteinases (MMPs) are synthesized (Gradinaru et al., 2017, 2018; Hansson and Libby, 2006; Libby, 2012; Libby et al., 2014; Ungurianu et al., 2019). |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T132 | 280-295 | Phenotype | denotes | atherosclerosis | http://purl.obolibrary.org/obo/HP_0002621 |
| T133 | 299-311 | Phenotype | denotes | dyslipidemia | http://purl.obolibrary.org/obo/HP_0003119 |
| T134 | 590-613 | Phenotype | denotes | endothelial dysfunction | http://purl.obolibrary.org/obo/HP_0032654 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32640331-27688246-30721016 | 1008-1012 | 27688246 | denotes | 2017 |
| 32640331-16778830-30721017 | 1039-1043 | 16778830 | denotes | 2006 |
| 32640331-22895665-30721018 | 1052-1056 | 22895665 | denotes | 2012 |
| 32640331-24902971-30721019 | 1072-1076 | 24902971 | denotes | 2014 |
| 32640331-30701670-30721020 | 1096-1100 | 30701670 | denotes | 2019 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32640331-27688246-30721016 | 1008-1012 | 27688246 | denotes | 2017 |
| 32640331-16778830-30721017 | 1039-1043 | 16778830 | denotes | 2006 |
| 32640331-22895665-30721018 | 1052-1056 | 22895665 | denotes | 2012 |
| 32640331-24902971-30721019 | 1072-1076 | 24902971 | denotes | 2014 |
| 32640331-30701670-30721020 | 1096-1100 | 30701670 | denotes | 2019 |