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PMC:7335494 / 59294-60243 JSONTXT

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LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T643 181-184 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T644 185-186 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T645 280-290 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T646 335-336 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T647 482-483 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T648 484-494 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T649 498-499 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T650 572-574 http://purl.obolibrary.org/obo/UBERON_0003064 denotes Im
T651 704-714 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling
T652 723-724 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T653 745-746 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T654 780-790 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T655 813-821 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T656 822-832 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T657 840-841 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T658 915-925 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T44030 0-3 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T342 8-11 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T82658 23-31 Chemical denotes agonists http://purl.obolibrary.org/obo/CHEBI_48705
T344 83-94 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T85681 104-116 Chemical denotes protectin D1 http://purl.obolibrary.org/obo/CHEBI_138655
T7860 170-173 Chemical denotes ALA http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432
T38169 177-180 Chemical denotes ARA http://purl.obolibrary.org/obo/CHEBI_15843
T54248 206-209 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T353 213-216 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T19797 331-333 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T28353 422-427 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T15370 446-451 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T68097 478-480 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T362 673-678 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T2536 719-721 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T66827 741-743 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T369 836-838 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T199 299-321 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T200 704-714 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T201 915-933 http://purl.obolibrary.org/obo/GO_0007165 denotes signalling cascade
T202 915-925 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T335 0-163 Sentence denotes DHA and EPA are weaker agonists of PPAR-γ (EC50 ~ 10–100 μM), while their oxidized metabolites (such as protectin D1) are much more potent (Yamamoto et al., 2005).
T336 164-269 Sentence denotes Also, ALA or ARA has a similar potency to DHA or EPA for on PPAR-γ, and higher for PPAR-α (Calder, 2015).
T337 270-428 Sentence denotes As PPAR-γ activation reduces inflammatory responses, via the NF-κB pathway, this mechanism could partially explain the anti-inflammatory effects of n-3 PUFAs.
T338 429-582 Sentence denotes Furthermore, n-3 PUFAs were reported to suppress NF-κB activation in a PPAR-γ-independent manner by binding to TLR-4 under certain conditions (Im, 2012).
T339 583-949 Sentence denotes Taking into account all these reports, it looks like three mechanisms are employed by n-3 PUFAs to suppress inflammatory signalling via NF-κB: (1) preventing NF-κB nuclear translocation via PPAR-γ activation, (2) interfering with membrane activation of NF-κB via TLR4 and (3) interaction with GPR120 initiating an anti-inflammatory signalling cascade (Calder, 2015).

MyTest

Id Subject Object Predicate Lexical cue
32640331-15664804-30720928 157-161 15664804 denotes 2005
32640331-25149823-30720929 263-267 25149823 denotes 2015
32640331-22542696-30720930 576-580 22542696 denotes 2012
32640331-25149823-30720931 943-947 25149823 denotes 2015

2_test

Id Subject Object Predicate Lexical cue
32640331-15664804-30720928 157-161 15664804 denotes 2005
32640331-25149823-30720929 263-267 25149823 denotes 2015
32640331-22542696-30720930 576-580 22542696 denotes 2012
32640331-25149823-30720931 943-947 25149823 denotes 2015