PMC:7335494 / 16638-17523
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4 | 578-585 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T128 | 69-72 | Body_part | denotes | ECM | http://purl.org/sig/ont/fma/fma9672 |
T129 | 96-103 | Body_part | denotes | insulin | http://purl.org/sig/ont/fma/fma83365 |
T130 | 133-140 | Body_part | denotes | Lumican | http://purl.org/sig/ont/fma/fma82827 |
T131 | 187-195 | Body_part | denotes | collagen | http://purl.org/sig/ont/fma/fma63891 |
T132 | 303-310 | Body_part | denotes | insulin | http://purl.org/sig/ont/fma/fma83365 |
T133 | 393-400 | Body_part | denotes | lumican | http://purl.org/sig/ont/fma/fma82827 |
T134 | 438-452 | Body_part | denotes | adipose tissue | http://purl.org/sig/ont/fma/fma20110 |
T135 | 509-512 | Body_part | denotes | ECM | http://purl.org/sig/ont/fma/fma9672 |
T136 | 513-520 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T137 | 521-528 | Body_part | denotes | lumican | http://purl.org/sig/ont/fma/fma82827 |
T138 | 569-572 | Body_part | denotes | ECM | http://purl.org/sig/ont/fma/fma9672 |
T139 | 578-585 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
T140 | 663-666 | Body_part | denotes | ECM | http://purl.org/sig/ont/fma/fma9672 |
T141 | 667-679 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T142 | 705-719 | Body_part | denotes | adipose tissue | http://purl.org/sig/ont/fma/fma20110 |
T143 | 720-731 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
T144 | 765-779 | Body_part | denotes | adipose tissue | http://purl.org/sig/ont/fma/fma20110 |
T145 | 822-829 | Body_part | denotes | insulin | http://purl.org/sig/ont/fma/fma83365 |
T146 | 882-885 | Body_part | denotes | ECM | http://purl.org/sig/ont/fma/fma9672 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T37 | 438-452 | Body_part | denotes | adipose tissue | http://purl.obolibrary.org/obo/UBERON_0001013 |
T38 | 446-452 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
T39 | 705-719 | Body_part | denotes | adipose tissue | http://purl.obolibrary.org/obo/UBERON_0001013 |
T40 | 713-719 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
T41 | 765-779 | Body_part | denotes | adipose tissue | http://purl.obolibrary.org/obo/UBERON_0001013 |
T42 | 773-779 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T64 | 284-291 | Disease | denotes | obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
T65 | 453-465 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T66 | 606-624 | Disease | denotes | metabolic syndrome | http://purl.obolibrary.org/obo/MONDO_0004955 |
T67 | 780-792 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T162 | 89-92 | http://purl.obolibrary.org/obo/UBERON_0001013 | denotes | fat |
T163 | 96-103 | http://purl.obolibrary.org/obo/PR_000009054 | denotes | insulin |
T164 | 171-183 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | organization |
T165 | 187-195 | http://purl.obolibrary.org/obo/CHEBI_3815 | denotes | collagen |
T166 | 303-310 | http://purl.obolibrary.org/obo/PR_000009054 | denotes | insulin |
T167 | 350-351 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T168 | 438-452 | http://purl.obolibrary.org/obo/UBERON_0001013 | denotes | adipose tissue |
T169 | 540-541 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T170 | 647-658 | http://purl.obolibrary.org/obo/PR_000015561 | denotes | Osteopontin |
T171 | 705-719 | http://purl.obolibrary.org/obo/UBERON_0001013 | denotes | adipose tissue |
T172 | 765-779 | http://purl.obolibrary.org/obo/UBERON_0001013 | denotes | adipose tissue |
T173 | 822-829 | http://purl.obolibrary.org/obo/PR_000009054 | denotes | insulin |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T148 | 96-103 | Chemical | denotes | insulin | http://purl.obolibrary.org/obo/CHEBI_145810 |
T149 | 303-310 | Chemical | denotes | insulin | http://purl.obolibrary.org/obo/CHEBI_145810 |
T150 | 513-520 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T151 | 578-585 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
T153 | 667-679 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T154 | 822-829 | Chemical | denotes | insulin | http://purl.obolibrary.org/obo/CHEBI_145810 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T81 | 211-223 | http://purl.obolibrary.org/obo/GO_0060612 | denotes | adipogenesis |
T82 | 211-223 | http://purl.obolibrary.org/obo/GO_0045444 | denotes | adipogenesis |
T83 | 453-465 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T84 | 578-597 | http://purl.obolibrary.org/obo/GO_0042593 | denotes | glucose homeostasis |
T85 | 586-597 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
T86 | 780-792 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T76 | 133-349 | Sentence | denotes | Lumican was demonstrated to alter the organization of collagen I, dysregulate adipogenesis and trigger oxidative stress, facilitating the pathology of obesity-associated insulin resistance (Guzman-Ruiz et al., 2020). |
T77 | 350-466 | Sentence | denotes | A separate study showed that the effect of lumican was diet-dependent and correlated to adipose tissue inflammation. |
T78 | 467-646 | Sentence | denotes | Indeed, the same authors suggest that the ECM protein lumican could pose a convergent point among the ECM, the glucose homeostasis and the metabolic syndrome (Wolff et al., 2019). |
T79 | 647-863 | Sentence | denotes | Osteopontin, an ECM glycoprotein, excessively secreted by adipose tissue macrophages (Nomiyama et al., 2007) enhances adipose tissue inflammation and facilitates the onset of insulin resistance (Aouadi et al., 2013). |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T38 | 96-113 | Phenotype | denotes | insulin resistant | http://purl.obolibrary.org/obo/HP_0000855 |
T39 | 236-252 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
T40 | 284-291 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
T41 | 303-321 | Phenotype | denotes | insulin resistance | http://purl.obolibrary.org/obo/HP_0000855 |
T42 | 822-840 | Phenotype | denotes | insulin resistance | http://purl.obolibrary.org/obo/HP_0000855 |
MyTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32640331-32293066-30720760 | 343-347 | 32293066 | denotes | 2020 |
32640331-30409703-30720761 | 640-644 | 30409703 | denotes | 2019 |
32640331-17823662-30720762 | 750-754 | 17823662 | denotes | 2007 |
32640331-23630254-30720763 | 857-861 | 23630254 | denotes | 2013 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32640331-32293066-30720760 | 343-347 | 32293066 | denotes | 2020 |
32640331-30409703-30720761 | 640-644 | 30409703 | denotes | 2019 |
32640331-17823662-30720762 | 750-754 | 17823662 | denotes | 2007 |
32640331-23630254-30720763 | 857-861 | 23630254 | denotes | 2013 |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T330 | 52-65 | GO:0010467 | denotes | overexpressed |
T331 | 69-72 | GO:0044420 | denotes | ECM |
T332 | 76-88 | UBERON:0002190 | denotes | subcutaneous |
T333 | 89-92 | UBERON:0001013 | denotes | fat |
T334 | 96-103 | PR:000009054 | denotes | insulin |
T335 | 120-131 | NCBITaxon:1 | denotes | individuals |
T336 | 199-210 | GO:0065007 | denotes | dysregulate |
T337 | 211-223 | GO:0060612 | denotes | adipogenesis |
T338 | 236-245 | MOP:0000568 | denotes | oxidative |
T339 | 303-310 | PR:000009054 | denotes | insulin |
T340 | 438-452 | UBERON:0001013 | denotes | adipose tissue |
T341 | 509-512 | GO:0044420 | denotes | ECM |
T342 | 569-572 | GO:0044420 | denotes | ECM |
T343 | 578-585 | CHEBI:17234;CHEBI:17234;GO:0042593 | denotes | glucose |
T344 | 586-597 | GO:0042593 | denotes | homeostasis |
T345 | 606-615 | GO:0008152 | denotes | metabolic |
T346 | 647-658 | PR:000015561 | denotes | Osteopontin |
T347 | 663-666 | GO:0044420 | denotes | ECM |
T348 | 667-679 | CHEBI:17089;BV_11;CHEBI:17089 | denotes | glycoprotein |
T349 | 693-701 | GO:0046903 | denotes | secreted |
T350 | 705-719 | UBERON:0001013 | denotes | adipose tissue |
T351 | 720-731 | CL:0000235 | denotes | macrophages |
T352 | 765-779 | UBERON:0001013 | denotes | adipose tissue |
T353 | 822-829 | PR:000009054 | denotes | insulin |