PMC:7321036 / 93432-94195
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T663 | 32-37 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T664 | 158-163 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T665 | 350-355 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T666 | 420-429 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
| T667 | 434-444 | Body_part | denotes | chemokines | http://purl.org/sig/ont/fma/fma241981 |
| T668 | 450-453 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T669 | 464-469 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T670 | 501-504 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T671 | 558-561 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T672 | 646-653 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T673 | 670-674 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T367 | 183-191 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T368 | 308-317 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1278 | 22-26 | http://purl.obolibrary.org/obo/CLO_0001601 | denotes | A549 |
| T1279 | 22-26 | http://purl.obolibrary.org/obo/CLO_0050025 | denotes | A549 |
| T1280 | 22-26 | http://purl.obolibrary.org/obo/CLO_0054264 | denotes | A549 |
| T1281 | 22-26 | http://purl.obolibrary.org/obo/CLO_0054265 | denotes | A549 |
| T1282 | 22-26 | http://purl.obolibrary.org/obo/CLO_0054266 | denotes | A549 |
| T1283 | 22-26 | http://purl.obolibrary.org/obo/CLO_0054267 | denotes | A549 |
| T1284 | 22-26 | http://purl.obolibrary.org/obo/CLO_0054268 | denotes | A549 |
| T1285 | 22-26 | http://purl.obolibrary.org/obo/CLO_0054269 | denotes | A549 |
| T1286 | 32-37 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1287 | 158-163 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1288 | 350-355 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1289 | 464-469 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1290 | 670-674 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T553 | 67-71 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T554 | 75-83 | Chemical | denotes | SB203580 | http://purl.obolibrary.org/obo/CHEBI_90705 |
| T555 | 252-261 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T556 | 646-653 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T557 | 714-720 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T558 | 737-740 | Chemical | denotes | SDS | http://purl.obolibrary.org/obo/CHEBI_8984 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T469 | 700-705 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | lysis |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2098 | 183-193 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 2099 | 67-71 | Chemical | denotes | DMSO | MESH:D004121 |
| 2100 | 75-83 | Chemical | denotes | SB203580 | MESH:C093642 |
| 2101 | 484-490 | Chemical | denotes | TRIzol | MESH:C411644 |
| 2102 | 709-720 | Chemical | denotes | RIPA buffer | |
| 2103 | 737-740 | Chemical | denotes | SDS | MESH:D012967 |
| 2104 | 169-177 | Disease | denotes | infected | MESH:D007239 |
| 2105 | 308-317 | Disease | denotes | infection | MESH:D007239 |
| 2106 | 341-349 | Disease | denotes | infected | MESH:D007239 |
| 2107 | 22-31 | CellLine | denotes | A549-ACE2 | CVCL:0023 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T820 | 0-126 | Sentence | denotes | Approximately 5 × 105 A549-ACE2 cells were pre-treated with either DMSO or SB203580 (0.01, 0.1, 1, 10 μM final concentration). |
| T821 | 127-318 | Sentence | denotes | After 1 hour of pre-treatment, cells were infected with SARS-CoV-2 (isolate USA-WA1/2020) at an MOI of 0.1 while maintaining inhibitor concentrations in the media for 30 hours post infection. |
| T822 | 319-445 | Sentence | denotes | The supernatants from infected cells were analyzed by multiplexed ELISA for the presence of secreted cytokines and chemokines. |
| T823 | 446-641 | Sentence | denotes | For RNA analysis, cells were lysed in TRIzol and total RNA was extracted and DNase treated using the Direct-zol RNA Miniprep Plus kit (Zymo Research) according to the manufacturer’s instructions. |
| T824 | 642-763 | Sentence | denotes | For protein analysis, whole cell lysates were obtained by lysis in RIPA buffer and analyzed by SDS-PAGE and western blot. |