PMC:7321036 / 50717-51268
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T253 | 94-103 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T254 | 303-318 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T255 | 309-318 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T256 | 410-418 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T257 | 421-430 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T676 | 43-53 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T677 | 196-204 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T678 | 222-227 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T679 | 259-267 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T19979 | 344-348 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T28590 | 471-476 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T71374 | 547-549 | Chemical | denotes | S8 | http://purl.obolibrary.org/obo/CHEBI_29385 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T359 | 11-26 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
| T360 | 125-140 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
| T361 | 252-267 | http://purl.obolibrary.org/obo/GO_0016301 | denotes | kinase activity |
| T362 | 303-318 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1124 | 222-227 | Species | denotes | human | Tax:9606 |
| 1125 | 94-103 | Disease | denotes | infection | MESH:D007239 |
| 1126 | 303-318 | Disease | denotes | viral infection | MESH:D001102 |
| 1127 | 410-430 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T334 | 0-104 | Sentence | denotes | Changes in phosphorylation reflect altered activities of kinases that are hijacked during the infection. |
| T335 | 105-236 | Sentence | denotes | Based on changes in phosphorylation of their annotated substrates, we estimated changes in activity of 97 of the 518 human kinases. |
| T336 | 237-319 | Sentence | denotes | The changes in kinase activity offer insights into the biology of viral infection. |
| T337 | 320-551 | Sentence | denotes | Kinases represent ideal drug targets; here, we identified kinases and pathways altered by SARS-CoV-2 infection that can be targeted by 87 FDA-approved drugs and compounds in clinical trials or in preclinical development (Table S8). |