PMC:7319919 / 1151-2699 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7319919","sourcedb":"PMC","sourceid":"7319919","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7319919","text":"On March 12, a 38-year-old woman was admitted to our department with a 6-day history of fever up to 39 °C, arthralgia, malaise and cough. Her blood pressure, heart rate and respiratory rate were all normal. Her temperature was 37.1 °C and oxygen saturation was 96% while she was breathing ambient air. Physical examination only revealed minimal wheezing on chest auscultation. Laboratory results showed a mild elevation of C-reactive protein (CRP) and lactate dehydrogenase (LDH) levels, and a normal lymphocyte count (Table 1 ). Chest X-ray confirmed bilateral pneumonia. Polymerase chain reaction test for SARS-CoV-2 in nasopharyngeal swab was positive, so treatment with HCQ and LPV/r, as well as empiric therapy with ceftriaxone, was initiated in accordance with hospital protocol.\nTable 1 - Laboratory results.\nVariable Day 6 of symptoms Day 10 of symptoms Day 13 of symptoms(day 2 of imatinib) Day 14 of symptoms(day 3 of imatinib) Day 16 of symptoms(day 5 of imatinib and discharge) 20 days after discharge\nCRP, mg/dL 4.79⁎ 21.00⁎ – 25.04⁎ 7.52⁎ 0.57⁎\nProcalcitonin, ng/mL – 0.1 0.09 0.06 0.05 0.01\nLDH, IU/L 338⁎ 532⁎ 318⁎ 306⁎ 326⁎ 222\nVenous lactate, mmol/L 1.0 3.2⁎ 2.7⁎ 2.5⁎ 1.6⁎ 1.1\nWhite-cell count, × 109/L 7.09 8.48 10.19 9.67 7.61 10.25\nNeutrophil count, × 109/L 5.44 6.76 8.29⁎ 7.92⁎ 5.56 6.07\nLymphocyte count, × 109/L 1.17 1.31 1.09 0.84† 1.35 3.14\nD-dimer, ng/mL – 580⁎ 760⁎ 1129⁎ – 449\nCRP = C-reactive protein; LDH = Lactate dehydrogenase.\n⁎ The value was above the reference range.\n† The value was below the reference 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