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PMC:7319613 / 6237-7420 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T109 24-28 GO:0007567 denotes born
T110 29-37 SP_7 denotes COVID-19
T111 124-128 G_3;PG_10;PR:000003622 denotes ACE2
T112 165-170 NCBITaxon:10239 denotes virus
T113 320-329 MOP:0000568 denotes oxidation
T114 343-355 CHEBI:33694;CHEBI:33694 denotes biomolecules
T115 366-379 CHEBI:16247;CHEBI:16247 denotes phospholipids
T116 420-424 UBERON:0002048 denotes lung
T117 433-442 MOP:0000568 denotes Oxidative
T118 468-480 GO:0005739 denotes mitochondria
T119 501-509 SP_7 denotes COVID-19
T120 675-693 UBERON:0001004 denotes respiratory system
T121 713-717 GO:0007567 denotes born
T122 718-728 NCBITaxon:1 denotes individual
T123 811-815 GO:0007567 denotes born
T124 816-827 NCBITaxon:1 denotes individuals
T125 872-880 SP_7 denotes COVID-19
T126 1063-1074 GO:0007567 denotes prematurity
T127 1079-1087 SP_7 denotes COVID-19
T72412 24-28 GO:0007567 denotes born
T97617 29-37 SP_7 denotes COVID-19
T27305 124-128 G_3;PG_10;PR:000003622 denotes ACE2
T82968 165-170 NCBITaxon:10239 denotes virus
T74303 320-329 MOP:0000568 denotes oxidation
T53175 343-355 CHEBI:33694;CHEBI:33694 denotes biomolecules
T76689 366-379 CHEBI:16247;CHEBI:16247 denotes phospholipids
T77422 420-424 UBERON:0002048 denotes lung
T14186 433-442 MOP:0000568 denotes Oxidative
T39931 468-480 GO:0005739 denotes mitochondria
T31003 501-509 SP_7 denotes COVID-19
T74764 675-693 UBERON:0001004 denotes respiratory system
T10239 713-717 GO:0007567 denotes born
T92930 718-728 NCBITaxon:1 denotes individual
T11700 811-815 GO:0007567 denotes born
T48125 816-827 NCBITaxon:1 denotes individuals
T28108 872-880 SP_7 denotes COVID-19
T76303 1063-1074 GO:0007567 denotes prematurity
T8584 1079-1087 SP_7 denotes COVID-19

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T15 366-379 Body_part denotes phospholipids http://purl.org/sig/ont/fma/fma82779
T16 420-424 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T17 675-693 Body_part denotes respiratory system http://purl.org/sig/ont/fma/fma7158

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T6 420-424 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 675-693 Body_part denotes respiratory system http://purl.obolibrary.org/obo/UBERON_0001004

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T32 29-37 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 88-97 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T34 196-205 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 425-431 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T36 501-509 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T37 872-880 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T38 1079-1087 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T32 129-137 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T33 165-170 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T34 212-213 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T35 420-424 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T36 420-424 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T37 649-650 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T38 675-693 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory system

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T17 366-379 Chemical denotes phospholipids http://purl.obolibrary.org/obo/CHEBI_16247
T18 453-459 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
147 124-128 Gene denotes ACE2 Gene:59272
148 38-46 Species denotes patients Tax:9606
149 881-889 Species denotes patients Tax:9606
150 366-379 Chemical denotes phospholipids MESH:D010743
151 453-459 Chemical denotes oxygen MESH:D010100
152 29-37 Disease denotes COVID-19 MESH:C000657245
153 88-97 Disease denotes infection MESH:D007239
154 196-205 Disease denotes infection MESH:D007239
155 420-431 Disease denotes lung injury MESH:D055370
156 501-509 Disease denotes COVID-19 MESH:C000657245
157 518-527 Disease denotes hypoxemia MESH:D000860
158 872-880 Disease denotes COVID-19 MESH:C000657245
159 1079-1087 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T23 518-527 Phenotype denotes hypoxemia http://purl.obolibrary.org/obo/HP_0012418

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T38 0-118 Sentence denotes In summary, prematurely born COVID-19 patients could be particularly vulnerable to both infection and adverse outcome.
T39 119-211 Sentence denotes High ACE2 activity levels may enable enhanced virus-binding, thus increasing infection risk.
T40 212-432 Sentence denotes A pre-existing adverse redox balance could then contribute to the aggravation of inflammatory mechanisms by oxidation of different biomolecules including phospholipids, incidentally exacerbating vascular and lung injury.
T41 433-729 Sentence denotes Oxidative damage to oxygen-sensing mitochondria in conjunction with COVID-19-related hypoxemia and prematurity-associated ventilator response deficits may synergistically deteriorate the health status facilitated by a potentially compromised respiratory system of the prematurely born individual.
T42 730-890 Sentence denotes We believe that the above-summarized data and mechanisms observed in prematurely born individuals should be considered when managing/treating COVID-19 patients.
T43 891-1183 Sentence denotes As no sound epidemiological data currently exist on the topic, future epidemiological and experimental efforts are urgently warranted to elucidate the relationship between prematurity and COVID-19 severity and thereby optimize therapeutic approaches for this, up-to-now neglected, population.