PMC:7319613 / 1292-2003 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T19","span":{"begin":80,"end":88},"obj":"SP_7"},{"id":"T20","span":{"begin":113,"end":117},"obj":"GO:0007567"},{"id":"T21","span":{"begin":118,"end":129},"obj":"NCBITaxon:1"},{"id":"T22","span":{"begin":142,"end":155},"obj":"GO:0007567"},{"id":"T23","span":{"begin":260,"end":271},"obj":"GO:0007567"},{"id":"T24","span":{"begin":490,"end":508},"obj":"UBERON:0001004;GO:0060541"},{"id":"T25","span":{"begin":509,"end":520},"obj":"GO:0060541"},{"id":"T26","span":{"begin":605,"end":614},"obj":"MOP:0000568"},{"id":"T27","span":{"begin":654,"end":683},"obj":"PR:000001322"},{"id":"T28","span":{"begin":685,"end":689},"obj":"PR:000003622;G_3;PG_10"},{"id":"T29","span":{"begin":700,"end":710},"obj":"GO:0010467"},{"id":"T49798","span":{"begin":80,"end":88},"obj":"SP_7"},{"id":"T9439","span":{"begin":113,"end":117},"obj":"GO:0007567"},{"id":"T82743","span":{"begin":118,"end":129},"obj":"NCBITaxon:1"},{"id":"T59112","span":{"begin":142,"end":155},"obj":"GO:0007567"},{"id":"T52406","span":{"begin":260,"end":271},"obj":"GO:0007567"},{"id":"T51892","span":{"begin":490,"end":508},"obj":"UBERON:0001004;GO:0060541"},{"id":"T46481","span":{"begin":509,"end":520},"obj":"GO:0060541"},{"id":"T82864","span":{"begin":605,"end":614},"obj":"MOP:0000568"},{"id":"T56875","span":{"begin":654,"end":683},"obj":"PR:000001322"},{"id":"T99491","span":{"begin":685,"end":689},"obj":"PR:000003622;G_3;PG_10"},{"id":"T70399","span":{"begin":700,"end":710},"obj":"GO:0010467"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":490,"end":508},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma7158"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":490,"end":508},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0001004"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T13","span":{"begin":80,"end":88},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T9","span":{"begin":282,"end":283},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T10","span":{"begin":490,"end":508},"obj":"http://purl.obolibrary.org/obo/UBERON_0001004"},{"id":"T11","span":{"begin":691,"end":699},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T2","span":{"begin":654,"end":665},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_2719"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PubTator","denotations":[{"id":"37","span":{"begin":654,"end":683},"obj":"Gene"},{"id":"38","span":{"begin":685,"end":689},"obj":"Gene"},{"id":"39","span":{"begin":80,"end":88},"obj":"Disease"}],"attributes":[{"id":"A37","pred":"tao:has_database_id","subj":"37","obj":"Gene:1636"},{"id":"A38","pred":"tao:has_database_id","subj":"38","obj":"Gene:59272"},{"id":"A39","pred":"tao:has_database_id","subj":"39","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T6","span":{"begin":605,"end":621},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0025464"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T2","span":{"begin":490,"end":520},"obj":"http://purl.obolibrary.org/obo/GO_0060541"},{"id":"T3","span":{"begin":502,"end":520},"obj":"http://purl.obolibrary.org/obo/GO_0048731"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}

{"project":"LitCovid-sentences","denotations":[{"id":"T9","span":{"begin":0,"end":130},"obj":"Sentence"},{"id":"T10","span":{"begin":131,"end":319},"obj":"Sentence"},{"id":"T11","span":{"begin":320,"end":440},"obj":"Sentence"},{"id":"T12","span":{"begin":441,"end":543},"obj":"Sentence"},{"id":"T13","span":{"begin":544,"end":711},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"One such, to-date neglected population that is potentially more »vulnerable« to COVID-19 consists of prematurely born individuals. Given that preterm birth prevalence is currently estimated at approximately 10 % births worldwide, the potential consequences of prematurity relate to a significant part of the population. We argue, that three important features associated with prematurity constitute the basis of such probable vulnerability: First, the detrimental long-term consequences on respiratory system development, control and function. Second, higher levels of (and possibly reduced tolerance to) oxidative stress and third, potentially elevated Angiotensin-converting enzyme (ACE2) activity/expression."}