PMC:7317273 / 21330-21832 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T142","span":{"begin":269,"end":278},"obj":"Body_part"},{"id":"T143","span":{"begin":366,"end":375},"obj":"Body_part"},{"id":"T144","span":{"begin":392,"end":400},"obj":"Body_part"}],"attributes":[{"id":"A142","pred":"fma_id","subj":"T142","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A144","pred":"fma_id","subj":"T144","obj":"http://purl.org/sig/ont/fma/fma12278"}],"text":"ings it could reasonably by presume that MSC priming is a significant approach for treating pulmonary anomalies. In the light of above findings, herein, we propose that the mechanism of priming of MSC could be implied to the following: i) Licensing by pro-inflammatory cytokines such as IFN-γ, TNF-α, etc., to enhance immunosuppressive potential; ii) Priming by non-cytokines stimuli such as hormones/growth factors like HGF to boost defensive and protective cellular mechanisms; iii) Pre-conditioning "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T249","span":{"begin":56,"end":57},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T250","span":{"begin":421,"end":424},"obj":"http://purl.obolibrary.org/obo/CLO_0003740"}],"text":"ings it could reasonably by presume that MSC priming is a significant approach for treating pulmonary anomalies. In the light of above findings, herein, we propose that the mechanism of priming of MSC could be implied to the following: i) Licensing by pro-inflammatory cytokines such as IFN-γ, TNF-α, etc., to enhance immunosuppressive potential; ii) Priming by non-cytokines stimuli such as hormones/growth factors like HGF to boost defensive and protective cellular mechanisms; iii) Pre-conditioning "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T86","span":{"begin":392,"end":400},"obj":"Chemical"}],"attributes":[{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_24621"}],"text":"ings it could reasonably by presume that MSC priming is a significant approach for treating pulmonary anomalies. In the light of above findings, herein, we propose that the mechanism of priming of MSC could be implied to the following: i) Licensing by pro-inflammatory cytokines such as IFN-γ, TNF-α, etc., to enhance immunosuppressive potential; ii) Priming by non-cytokines stimuli such as hormones/growth factors like HGF to boost defensive and protective cellular mechanisms; iii) Pre-conditioning "}

{"project":"LitCovid-PubTator","denotations":[{"id":"324","span":{"begin":287,"end":292},"obj":"Gene"},{"id":"325","span":{"begin":294,"end":299},"obj":"Gene"},{"id":"326","span":{"begin":421,"end":424},"obj":"Gene"},{"id":"338","span":{"begin":92,"end":111},"obj":"Disease"}],"attributes":[{"id":"A324","pred":"tao:has_database_id","subj":"324","obj":"Gene:3458"},{"id":"A325","pred":"tao:has_database_id","subj":"325","obj":"Gene:7124"},{"id":"A326","pred":"tao:has_database_id","subj":"326","obj":"Gene:3082"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"MESH:D008171"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ings it could reasonably by presume that MSC priming is a significant approach for treating pulmonary anomalies. In the light of above findings, herein, we propose that the mechanism of priming of MSC could be implied to the following: i) Licensing by pro-inflammatory cytokines such as IFN-γ, TNF-α, etc., to enhance immunosuppressive potential; ii) Priming by non-cytokines stimuli such as hormones/growth factors like HGF to boost defensive and protective cellular mechanisms; iii) Pre-conditioning "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T22","span":{"begin":401,"end":407},"obj":"http://purl.obolibrary.org/obo/GO_0040007"}],"text":"ings it could reasonably by presume that MSC priming is a significant approach for treating pulmonary anomalies. In the light of above findings, herein, we propose that the mechanism of priming of MSC could be implied to the following: i) Licensing by pro-inflammatory cytokines such as IFN-γ, TNF-α, etc., to enhance immunosuppressive potential; ii) Priming by non-cytokines stimuli such as hormones/growth factors like HGF to boost defensive and protective cellular mechanisms; iii) Pre-conditioning "}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T367","span":{"begin":92,"end":101},"obj":"UBERON:0002048"},{"id":"T368","span":{"begin":287,"end":292},"obj":"PR:000000017"},{"id":"T369","span":{"begin":294,"end":299},"obj":"PR:000000134"},{"id":"T370","span":{"begin":318,"end":335},"obj":"CHEBI:35705;CHEBI:35705"},{"id":"T371","span":{"begin":421,"end":424},"obj":"PR:000008534"},{"id":"T372","span":{"begin":434,"end":443},"obj":"GO:0006952"}],"text":"ings it could reasonably by presume that MSC priming is a significant approach for treating pulmonary anomalies. In the light of above findings, herein, we propose that the mechanism of priming of MSC could be implied to the following: i) Licensing by pro-inflammatory cytokines such as IFN-γ, TNF-α, etc., to enhance immunosuppressive potential; ii) Priming by non-cytokines stimuli such as hormones/growth factors like HGF to boost defensive and protective cellular mechanisms; iii) Pre-conditioning "}