PMC:7314078 / 12914-14608 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T3","span":{"begin":447,"end":459},"obj":"Body_part"},{"id":"T4","span":{"begin":623,"end":635},"obj":"Body_part"},{"id":"T5","span":{"begin":747,"end":763},"obj":"Body_part"},{"id":"T6","span":{"begin":895,"end":898},"obj":"Body_part"},{"id":"T7","span":{"begin":1222,"end":1227},"obj":"Body_part"},{"id":"T8","span":{"begin":1264,"end":1269},"obj":"Body_part"},{"id":"T9","span":{"begin":1518,"end":1521},"obj":"Body_part"},{"id":"T10","span":{"begin":1565,"end":1580},"obj":"Body_part"},{"id":"T11","span":{"begin":1635,"end":1640},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma7236"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma7235"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma12154"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma3862"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma3862"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma49893"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma7088"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T3","span":{"begin":447,"end":459},"obj":"Body_part"},{"id":"T4","span":{"begin":454,"end":459},"obj":"Body_part"},{"id":"T5","span":{"begin":623,"end":635},"obj":"Body_part"},{"id":"T6","span":{"begin":630,"end":635},"obj":"Body_part"},{"id":"T7","span":{"begin":1163,"end":1168},"obj":"Body_part"},{"id":"T8","span":{"begin":1222,"end":1227},"obj":"Body_part"},{"id":"T9","span":{"begin":1264,"end":1269},"obj":"Body_part"},{"id":"T10","span":{"begin":1442,"end":1447},"obj":"Body_part"},{"id":"T11","span":{"begin":1565,"end":1580},"obj":"Body_part"},{"id":"T12","span":{"begin":1574,"end":1580},"obj":"Body_part"},{"id":"T13","span":{"begin":1635,"end":1640},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0002137"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0003978"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0002135"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0003978"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0003978"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/UBERON_0003978"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0001621"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T73","span":{"begin":95,"end":103},"obj":"Disease"},{"id":"T74","span":{"begin":233,"end":239},"obj":"Disease"},{"id":"T76","span":{"begin":288,"end":303},"obj":"Disease"},{"id":"T77","span":{"begin":320,"end":335},"obj":"Disease"},{"id":"T78","span":{"begin":349,"end":364},"obj":"Disease"},{"id":"T79","span":{"begin":371,"end":385},"obj":"Disease"},{"id":"T80","span":{"begin":434,"end":446},"obj":"Disease"},{"id":"T81","span":{"begin":468,"end":483},"obj":"Disease"},{"id":"T83","span":{"begin":555,"end":575},"obj":"Disease"},{"id":"T84","span":{"begin":644,"end":659},"obj":"Disease"},{"id":"T85","span":{"begin":719,"end":739},"obj":"Disease"},{"id":"T86","span":{"begin":831,"end":846},"obj":"Disease"},{"id":"T87","span":{"begin":895,"end":898},"obj":"Disease"},{"id":"T88","span":{"begin":963,"end":978},"obj":"Disease"},{"id":"T89","span":{"begin":985,"end":997},"obj":"Disease"},{"id":"T90","span":{"begin":1222,"end":1235},"obj":"Disease"},{"id":"T91","span":{"begin":1264,"end":1277},"obj":"Disease"},{"id":"T92","span":{"begin":1336,"end":1353},"obj":"Disease"},{"id":"T93","span":{"begin":1361,"end":1367},"obj":"Disease"},{"id":"T94","span":{"begin":1482,"end":1490},"obj":"Disease"},{"id":"T95","span":{"begin":1492,"end":1516},"obj":"Disease"},{"id":"T96","span":{"begin":1518,"end":1521},"obj":"Disease"}],"attributes":[{"id":"A73","pred":"mondo_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A74","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0005098"},{"id":"A75","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A76","pred":"mondo_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/MONDO_0005160"},{"id":"A77","pred":"mondo_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/MONDO_0005160"},{"id":"A78","pred":"mondo_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/MONDO_0007947"},{"id":"A79","pred":"mondo_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/MONDO_0004603"},{"id":"A80","pred":"mondo_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0004978"},{"id":"A82","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0042981"},{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0005648"},{"id":"A84","pred":"mondo_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/MONDO_0005852"},{"id":"A85","pred":"mondo_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/MONDO_0001298"},{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0006805"},{"id":"A87","pred":"mondo_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/MONDO_0017570"},{"id":"A88","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0020983"},{"id":"A89","pred":"mondo_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/MONDO_0005025"},{"id":"A90","pred":"mondo_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/MONDO_0005252"},{"id":"A91","pred":"mondo_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/MONDO_0005252"},{"id":"A92","pred":"mondo_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/MONDO_0001297"},{"id":"A93","pred":"mondo_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/MONDO_0044784"},{"id":"A94","pred":"mondo_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A95","pred":"mondo_id","subj":"T95","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A96","pred":"mondo_id","subj":"T96","obj":"http://purl.obolibrary.org/obo/MONDO_0017570"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T93","span":{"begin":119,"end":125},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T94","span":{"begin":142,"end":148},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T95","span":{"begin":288,"end":294},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T96","span":{"begin":320,"end":326},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T97","span":{"begin":447,"end":453},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T98","span":{"begin":454,"end":459},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T99","span":{"begin":468,"end":474},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T100","span":{"begin":555,"end":561},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T101","span":{"begin":630,"end":635},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T102","span":{"begin":757,"end":763},"obj":"http://purl.obolibrary.org/obo/UBERON_0001630"},{"id":"T103","span":{"begin":757,"end":763},"obj":"http://purl.obolibrary.org/obo/UBERON_0005090"},{"id":"T104","span":{"begin":757,"end":763},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T105","span":{"begin":757,"end":763},"obj":"http://www.ebi.ac.uk/efo/EFO_0001949"},{"id":"T106","span":{"begin":1163,"end":1168},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T107","span":{"begin":1222,"end":1227},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T108","span":{"begin":1222,"end":1227},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T109","span":{"begin":1222,"end":1227},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T110","span":{"begin":1222,"end":1227},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T111","span":{"begin":1264,"end":1269},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T112","span":{"begin":1264,"end":1269},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T113","span":{"begin":1264,"end":1269},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T114","span":{"begin":1264,"end":1269},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T115","span":{"begin":1442,"end":1447},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T116","span":{"begin":1574,"end":1580},"obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"T117","span":{"begin":1574,"end":1580},"obj":"http://www.ebi.ac.uk/efo/EFO_0000814"},{"id":"T118","span":{"begin":1612,"end":1618},"obj":"http://purl.obolibrary.org/obo/OBI_0000968"},{"id":"T119","span":{"begin":1635,"end":1640},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T120","span":{"begin":1635,"end":1640},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T121","span":{"begin":1635,"end":1640},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T122","span":{"begin":1635,"end":1640},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T10","span":{"begin":544,"end":546},"obj":"Chemical"},{"id":"T11","span":{"begin":895,"end":898},"obj":"Chemical"},{"id":"T12","span":{"begin":1439,"end":1441},"obj":"Chemical"},{"id":"T13","span":{"begin":1460,"end":1462},"obj":"Chemical"},{"id":"T14","span":{"begin":1518,"end":1521},"obj":"Chemical"}],"attributes":[{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_74327"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_73524"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_73809"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_73809"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_73524"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

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Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

{"project":"LitCovid-sentences","denotations":[{"id":"T113","span":{"begin":0,"end":8},"obj":"Sentence"},{"id":"T114","span":{"begin":10,"end":112},"obj":"Sentence"},{"id":"T115","span":{"begin":113,"end":277},"obj":"Sentence"},{"id":"T116","span":{"begin":278,"end":309},"obj":"Sentence"},{"id":"T117","span":{"begin":310,"end":348},"obj":"Sentence"},{"id":"T118","span":{"begin":349,"end":388},"obj":"Sentence"},{"id":"T119","span":{"begin":389,"end":420},"obj":"Sentence"},{"id":"T120","span":{"begin":421,"end":446},"obj":"Sentence"},{"id":"T121","span":{"begin":447,"end":547},"obj":"Sentence"},{"id":"T122","span":{"begin":548,"end":580},"obj":"Sentence"},{"id":"T123","span":{"begin":581,"end":597},"obj":"Sentence"},{"id":"T124","span":{"begin":598,"end":622},"obj":"Sentence"},{"id":"T125","span":{"begin":623,"end":664},"obj":"Sentence"},{"id":"T126","span":{"begin":665,"end":684},"obj":"Sentence"},{"id":"T127","span":{"begin":685,"end":709},"obj":"Sentence"},{"id":"T128","span":{"begin":710,"end":712},"obj":"Sentence"},{"id":"T129","span":{"begin":713,"end":807},"obj":"Sentence"},{"id":"T130","span":{"begin":808,"end":846},"obj":"Sentence"},{"id":"T131","span":{"begin":847,"end":872},"obj":"Sentence"},{"id":"T132","span":{"begin":873,"end":928},"obj":"Sentence"},{"id":"T133","span":{"begin":929,"end":978},"obj":"Sentence"},{"id":"T134","span":{"begin":979,"end":1130},"obj":"Sentence"},{"id":"T135","span":{"begin":1131,"end":1221},"obj":"Sentence"},{"id":"T136","span":{"begin":1222,"end":1238},"obj":"Sentence"},{"id":"T137","span":{"begin":1239,"end":1263},"obj":"Sentence"},{"id":"T138","span":{"begin":1264,"end":1320},"obj":"Sentence"},{"id":"T139","span":{"begin":1321,"end":1353},"obj":"Sentence"},{"id":"T140","span":{"begin":1354,"end":1398},"obj":"Sentence"},{"id":"T141","span":{"begin":1399,"end":1419},"obj":"Sentence"},{"id":"T142","span":{"begin":1420,"end":1459},"obj":"Sentence"},{"id":"T143","span":{"begin":1460,"end":1625},"obj":"Sentence"},{"id":"T144","span":{"begin":1626,"end":1694},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T17","span":{"begin":142,"end":159},"obj":"Phenotype"},{"id":"T18","span":{"begin":206,"end":210},"obj":"Phenotype"},{"id":"T19","span":{"begin":233,"end":239},"obj":"Phenotype"},{"id":"T20","span":{"begin":278,"end":303},"obj":"Phenotype"},{"id":"T21","span":{"begin":310,"end":335},"obj":"Phenotype"},{"id":"T22","span":{"begin":389,"end":397},"obj":"Phenotype"},{"id":"T23","span":{"begin":434,"end":446},"obj":"Phenotype"},{"id":"T24","span":{"begin":468,"end":483},"obj":"Phenotype"},{"id":"T25","span":{"begin":526,"end":534},"obj":"Phenotype"},{"id":"T26","span":{"begin":555,"end":575},"obj":"Phenotype"},{"id":"T27","span":{"begin":581,"end":597},"obj":"Phenotype"},{"id":"T28","span":{"begin":644,"end":659},"obj":"Phenotype"},{"id":"T29","span":{"begin":665,"end":681},"obj":"Phenotype"},{"id":"T30","span":{"begin":719,"end":739},"obj":"Phenotype"},{"id":"T31","span":{"begin":791,"end":807},"obj":"Phenotype"},{"id":"T32","span":{"begin":985,"end":997},"obj":"Phenotype"},{"id":"T33","span":{"begin":1222,"end":1235},"obj":"Phenotype"},{"id":"T34","span":{"begin":1264,"end":1277},"obj":"Phenotype"}],"attributes":[{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0002647"},{"id":"A18","pred":"hp_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/HP_0001259"},{"id":"A19","pred":"hp_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/HP_0001297"},{"id":"A20","pred":"hp_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/HP_0004970"},{"id":"A21","pred":"hp_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/HP_0004970"},{"id":"A22","pred":"hp_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/HP_0002617"},{"id":"A23","pred":"hp_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A24","pred":"hp_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/HP_0001650"},{"id":"A25","pred":"hp_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/HP_0002094"},{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/HP_0001659"},{"id":"A27","pred":"hp_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/HP_0100598"},{"id":"A28","pred":"hp_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/HP_0001718"},{"id":"A29","pred":"hp_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/HP_0100598"},{"id":"A30","pred":"hp_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/HP_0001653"},{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0100598"},{"id":"A32","pred":"hp_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/HP_0100584"},{"id":"A33","pred":"hp_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/HP_0001635"},{"id":"A34","pred":"hp_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/HP_0001635"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}

{"project":"testtesttest","denotations":[{"id":"T17","span":{"begin":447,"end":459},"obj":"Body_part"},{"id":"T18","span":{"begin":623,"end":635},"obj":"Body_part"},{"id":"T19","span":{"begin":747,"end":763},"obj":"Body_part"},{"id":"T20","span":{"begin":1163,"end":1168},"obj":"Body_part"},{"id":"T21","span":{"begin":1222,"end":1227},"obj":"Body_part"},{"id":"T25","span":{"begin":1264,"end":1269},"obj":"Body_part"},{"id":"T29","span":{"begin":1439,"end":1447},"obj":"Body_part"},{"id":"T30","span":{"begin":1565,"end":1580},"obj":"Body_part"},{"id":"T31","span":{"begin":1635,"end":1640},"obj":"Body_part"}],"attributes":[{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0002137"},{"id":"A18","pred":"uberon_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/UBERON_0002135"},{"id":"A19","pred":"uberon_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/UBERON_0002494"},{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/UBERON_0003978"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A22","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"A23","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"A24","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0015230"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A26","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"A27","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"A28","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0015230"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0002133"},{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_0001621"},{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A32","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"A33","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"A34","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0015230"}],"text":"Table 2: Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak\nAcute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age \u003e80 years with stroke and/or evident visceral malperfusion)\nAscending aortic aneurysm ≥6 cm\nAscending aortic aneurysm ≥5.5 cm AND:\nMarfan syndrome/other collagenopathy OR\nAneurysm increase \u003e5 mm/year OR\nUncontrolled hypertension\nAortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)\nSevere aortic regurgitation AND:\nPulmonary oedema\nHaemodynamic instability\nMitral valve Severe mitral stenosis AND:\nPulmonary oedema OR\nHaemodynamic instability\n2. Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema\nIschaemic cardiopathy Unstable angina\nSevere LMCA stenosis ≥70%\nSubocclusive proximal LAD stenosis not suitable for PCI\nPostinfarction ventricular septal/cardiac rupture\nAcute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)\nSevere bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in: Heart failure OR\nHaemodynamic instability\nHeart failure Non-deferrable need for LVAD implantation\nMiscellaneous Cardiac tamponade\nAtrial myxoma OR other cardiac tumours with:\nHigh embolic risk OR\nIn the presence of AV valve obstruction\nAV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA: New York Heart Association; PCI: percutaneous coronary intervention."}