
PMC:7309518 / 772-2213
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T4 | 369-380 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
T5 | 462-469 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T6 | 507-520 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
T7 | 525-529 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T8 | 638-650 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
T9 | 655-671 | Body_part | denotes | peripheral nerve | http://purl.org/sig/ont/fma/fma65239 |
T10 | 672-683 | Body_part | denotes | glycolipids | http://purl.org/sig/ont/fma/fma82780 |
T11 | 825-831 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T12 | 951-960 | Body_part | denotes | brainstem | http://purl.org/sig/ont/fma/fma79876 |
T13 | 1287-1291 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T2 | 666-671 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T3 | 951-960 | Body_part | denotes | brainstem | http://purl.obolibrary.org/obo/UBERON_0002298 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T18 | 107-110 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T19 | 112-129 | Disease | denotes | encephalomyelitis | http://purl.obolibrary.org/obo/MONDO_0005156 |
T20 | 133-141 | Disease | denotes | myositis | http://purl.obolibrary.org/obo/MONDO_0008054|http://purl.obolibrary.org/obo/MONDO_0021167 |
T22 | 215-223 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T23 | 225-232 | Disease | denotes | Anosmia | http://purl.obolibrary.org/obo/MONDO_0010528 |
T24 | 249-269 | Disease | denotes | cranial neuropathies | http://purl.obolibrary.org/obo/MONDO_0003569 |
T25 | 274-289 | Disease | denotes | lymphocytopenia | http://purl.obolibrary.org/obo/MONDO_0003783 |
T26 | 345-367 | Disease | denotes | Miller-Fisher Syndrome | http://purl.obolibrary.org/obo/MONDO_0005851 |
T27 | 447-455 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T28 | 584-594 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
T29 | 621-629 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T30 | 756-764 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T31 | 876-884 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T32 | 895-898 | Disease | denotes | NAM | http://purl.obolibrary.org/obo/MONDO_0009722|http://purl.obolibrary.org/obo/MONDO_0016098 |
T34 | 961-973 | Disease | denotes | encephalitis | http://purl.obolibrary.org/obo/MONDO_0019956 |
T35 | 975-995 | Disease | denotes | cranial neuropathies | http://purl.obolibrary.org/obo/MONDO_0003569 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3 | 525-529 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T4 | 655-671 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | peripheral nerve |
T5 | 825-831 | http://purl.obolibrary.org/obo/UBERON_0001630 | denotes | muscle |
T6 | 825-831 | http://purl.obolibrary.org/obo/UBERON_0005090 | denotes | muscle |
T7 | 825-831 | http://www.ebi.ac.uk/efo/EFO_0000801 | denotes | muscle |
T8 | 825-831 | http://www.ebi.ac.uk/efo/EFO_0001949 | denotes | muscle |
T9 | 1285-1291 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T3 | 369-380 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
T4 | 400-404 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
T5 | 462-469 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T6 | 484-495 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
T7 | 491-495 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T8 | 507-520 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
T9 | 545-549 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
T10 | 638-650 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
T11 | 672-683 | Chemical | denotes | glycolipids | http://purl.obolibrary.org/obo/CHEBI_33563 |
T12 | 708-716 | Chemical | denotes | Creatine | http://purl.obolibrary.org/obo/CHEBI_16919 |
T13 | 1231-1239 | Chemical | denotes | steroids | http://purl.obolibrary.org/obo/CHEBI_35341 |
T14 | 1241-1254 | Chemical | denotes | mycophenolate | http://purl.obolibrary.org/obo/CHEBI_62932 |
T15 | 1256-1268 | Chemical | denotes | azathioprine | http://purl.obolibrary.org/obo/CHEBI_2948 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
49 | 708-723 | Gene | denotes | Creatine Kinase | Gene:51727 |
50 | 51-58 | Species | denotes | patient | Tax:9606 |
51 | 298-303 | Species | denotes | flags | Tax:34205 |
52 | 774-782 | Species | denotes | patients | Tax:9606 |
53 | 793-801 | Species | denotes | patients | Tax:9606 |
54 | 369-380 | Chemical | denotes | ganglioside | MESH:D005732 |
55 | 484-495 | Chemical | denotes | sialic acid | MESH:D019158 |
56 | 638-650 | Chemical | denotes | gangliosides | MESH:D005732 |
57 | 672-683 | Chemical | denotes | glycolipids | MESH:D006017 |
58 | 1231-1239 | Chemical | denotes | steroids | MESH:D013256 |
59 | 1241-1254 | Chemical | denotes | mycophenolate | MESH:D009173 |
60 | 1256-1268 | Chemical | denotes | azathioprine | MESH:D001379 |
61 | 78-101 | Disease | denotes | acute paralytic disease | MESH:D000208 |
62 | 112-129 | Disease | denotes | encephalomyelitis | MESH:D004679 |
63 | 133-141 | Disease | denotes | myositis | MESH:D009220 |
64 | 215-223 | Disease | denotes | COVID-19 | MESH:C000657245 |
65 | 234-241 | Disease | denotes | ageusia | MESH:D000370 |
66 | 249-269 | Disease | denotes | cranial neuropathies | MESH:D003389 |
67 | 274-289 | Disease | denotes | lymphocytopenia | MESH:D008231 |
68 | 345-367 | Disease | denotes | Miller-Fisher Syndrome | MESH:D019846 |
69 | 447-455 | Disease | denotes | COVID-19 | MESH:C000657245 |
70 | 577-594 | Disease | denotes | ataxic neuropathy | MESH:D001039 |
71 | 621-629 | Disease | denotes | COVID-19 | MESH:C000657245 |
72 | 756-773 | Disease | denotes | COVID-19–infected | MESH:C000657245 |
73 | 817-840 | Disease | denotes | painful muscle weakness | MESH:D018908 |
74 | 876-884 | Disease | denotes | COVID-19 | MESH:C000657245 |
75 | 961-973 | Disease | denotes | encephalitis | MESH:D004660 |
76 | 975-995 | Disease | denotes | cranial neuropathies | MESH:D003389 |
77 | 1069-1090 | Disease | denotes | demyelinating lesions | MESH:D003711 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 1341-1356 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immunity |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 0-224 | Sentence | denotes | Collective data indicate that in this pandemic any patient presenting with an acute paralytic disease-like GBS, encephalomyelitis or myositis-even without systemic symptoms, may represent the first manifestation of COVID-19. |
T12 | 225-341 | Sentence | denotes | Anosmia, ageusia, other cranial neuropathies and lymphocytopenia are red flags enhancing early diagnostic suspicion. |
T13 | 342-698 | Sentence | denotes | In Miller-Fisher Syndrome, ganglioside antibodies against GD1b, instead of QG1b, were found; because the COVID-19 spike protein also binds to sialic acid-containing glycoproteins for cell-entry and anti-GD1b antibodies typically cause ataxic neuropathy, cross-reactivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. |
T14 | 699-923 | Sentence | denotes | Elevated Creatine Kinase (>10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. |
T15 | 924-1164 | Sentence | denotes | Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. |
T16 | 1165-1441 | Sentence | denotes | Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were addressed; the role of complement in innate immunity to viral responses and anti-complement therapeutics (i.e. eculizumab) were reviewed. |
LitCovid-PD-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
---|---|---|---|---|---|
T1 | 400-404 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
T2 | 540-549 | GlycoEpitope | denotes | anti-GD1b | http://www.glycoepitope.jp/epitopes/AN0403 |
T3 | 545-549 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T7 | 133-141 | Phenotype | denotes | myositis | http://purl.obolibrary.org/obo/HP_0100614 |
T8 | 225-232 | Phenotype | denotes | Anosmia | http://purl.obolibrary.org/obo/HP_0000458 |
T9 | 234-241 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
T10 | 274-289 | Phenotype | denotes | lymphocytopenia | http://purl.obolibrary.org/obo/HP_0001888 |
T11 | 584-594 | Phenotype | denotes | neuropathy | http://purl.obolibrary.org/obo/HP_0009830 |
T12 | 699-723 | Phenotype | denotes | Elevated Creatine Kinase | http://purl.obolibrary.org/obo/HP_0003236 |
T13 | 825-840 | Phenotype | denotes | muscle weakness | http://purl.obolibrary.org/obo/HP_0001324 |
T14 | 961-973 | Phenotype | denotes | encephalitis | http://purl.obolibrary.org/obo/HP_0002383 |
T15 | 1001-1027 | Phenotype | denotes | leptomeningeal enhancement | http://purl.obolibrary.org/obo/HP_0032070 |
T16 | 1069-1082 | Phenotype | denotes | demyelinating | http://purl.obolibrary.org/obo/HP_0011096 |
T17 | 1151-1163 | Phenotype | denotes | autoimmunity | http://purl.obolibrary.org/obo/HP_0002960 |