PMC:7309518 / 6401-7212 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T27","span":{"begin":111,"end":126},"obj":"Body_part"},{"id":"T28","span":{"begin":242,"end":248},"obj":"Body_part"},{"id":"T29","span":{"begin":308,"end":315},"obj":"Body_part"},{"id":"T30","span":{"begin":414,"end":417},"obj":"Body_part"},{"id":"T31","span":{"begin":434,"end":441},"obj":"Body_part"},{"id":"T32","span":{"begin":591,"end":602},"obj":"Body_part"},{"id":"T33","span":{"begin":591,"end":596},"obj":"Body_part"},{"id":"T34","span":{"begin":606,"end":618},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma7184"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma228738"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma5981"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma65132"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma50868"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T13","span":{"begin":242,"end":248},"obj":"Body_part"},{"id":"T14","span":{"begin":591,"end":602},"obj":"Body_part"},{"id":"T15","span":{"begin":591,"end":596},"obj":"Body_part"},{"id":"T16","span":{"begin":606,"end":618},"obj":"Body_part"},{"id":"T17","span":{"begin":613,"end":618},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0000341"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0002211"},{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0001021"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0001647"},{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0001021"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T99","span":{"begin":40,"end":43},"obj":"Disease"},{"id":"T100","span":{"begin":215,"end":222},"obj":"Disease"},{"id":"T101","span":{"begin":237,"end":248},"obj":"Disease"},{"id":"T102","span":{"begin":272,"end":287},"obj":"Disease"},{"id":"T103","span":{"begin":347,"end":355},"obj":"Disease"},{"id":"T104","span":{"begin":401,"end":407},"obj":"Disease"},{"id":"T105","span":{"begin":477,"end":485},"obj":"Disease"},{"id":"T106","span":{"begin":549,"end":552},"obj":"Disease"},{"id":"T107","span":{"begin":651,"end":662},"obj":"Disease"}],"attributes":[{"id":"A99","pred":"mondo_id","subj":"T99","obj":"http://purl.obolibrary.org/obo/MONDO_0016218"},{"id":"A100","pred":"mondo_id","subj":"T100","obj":"http://purl.obolibrary.org/obo/MONDO_0010528"},{"id":"A101","pred":"mondo_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/MONDO_0002258"},{"id":"A102","pred":"mondo_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/MONDO_0003783"},{"id":"A103","pred":"mondo_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A104","pred":"mondo_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/MONDO_0000437"},{"id":"A105","pred":"mondo_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A106","pred":"mondo_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/MONDO_0016218"},{"id":"A107","pred":"mondo_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/MONDO_0001590"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T41","span":{"begin":6,"end":9},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T42","span":{"begin":117,"end":126},"obj":"http://www.ebi.ac.uk/efo/EFO_0000876"},{"id":"T43","span":{"begin":591,"end":596},"obj":"http://purl.obolibrary.org/obo/UBERON_0001021"},{"id":"T44","span":{"begin":613,"end":618},"obj":"http://purl.obolibrary.org/obo/UBERON_0001021"},{"id":"T45","span":{"begin":727,"end":730},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"},{"id":"T46","span":{"begin":731,"end":737},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T19","span":{"begin":308,"end":315},"obj":"Chemical"},{"id":"T20","span":{"begin":434,"end":441},"obj":"Chemical"}],"attributes":[{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}

{"project":"LitCovid-PubTator","denotations":[{"id":"239","span":{"begin":297,"end":315},"obj":"Gene"},{"id":"240","span":{"begin":317,"end":320},"obj":"Gene"},{"id":"241","span":{"begin":414,"end":417},"obj":"Gene"},{"id":"242","span":{"begin":26,"end":34},"obj":"Species"},{"id":"243","span":{"begin":361,"end":368},"obj":"Species"},{"id":"244","span":{"begin":738,"end":746},"obj":"Species"},{"id":"245","span":{"begin":111,"end":135},"obj":"Disease"},{"id":"246","span":{"begin":162,"end":178},"obj":"Disease"},{"id":"247","span":{"begin":208,"end":213},"obj":"Disease"},{"id":"248","span":{"begin":215,"end":222},"obj":"Disease"},{"id":"249","span":{"begin":224,"end":231},"obj":"Disease"},{"id":"250","span":{"begin":237,"end":248},"obj":"Disease"},{"id":"251","span":{"begin":272,"end":287},"obj":"Disease"},{"id":"252","span":{"begin":347,"end":355},"obj":"Disease"},{"id":"253","span":{"begin":373,"end":407},"obj":"Disease"},{"id":"254","span":{"begin":477,"end":485},"obj":"Disease"},{"id":"255","span":{"begin":525,"end":538},"obj":"Disease"},{"id":"256","span":{"begin":651,"end":662},"obj":"Disease"},{"id":"257","span":{"begin":806,"end":810},"obj":"Disease"}],"attributes":[{"id":"A239","pred":"tao:has_database_id","subj":"239","obj":"Gene:1401"},{"id":"A240","pred":"tao:has_database_id","subj":"240","obj":"Gene:1401"},{"id":"A241","pred":"tao:has_database_id","subj":"241","obj":"Gene:1437"},{"id":"A242","pred":"tao:has_database_id","subj":"242","obj":"Tax:9606"},{"id":"A243","pred":"tao:has_database_id","subj":"243","obj":"Tax:9606"},{"id":"A244","pred":"tao:has_database_id","subj":"244","obj":"Tax:9606"},{"id":"A245","pred":"tao:has_database_id","subj":"245","obj":"MESH:D020335"},{"id":"A246","pred":"tao:has_database_id","subj":"246","obj":"MESH:D012678"},{"id":"A247","pred":"tao:has_database_id","subj":"247","obj":"MESH:D003371"},{"id":"A248","pred":"tao:has_database_id","subj":"248","obj":"MESH:D000857"},{"id":"A249","pred":"tao:has_database_id","subj":"249","obj":"MESH:D000370"},{"id":"A250","pred":"tao:has_database_id","subj":"250","obj":"MESH:D010608"},{"id":"A251","pred":"tao:has_database_id","subj":"251","obj":"MESH:D008231"},{"id":"A252","pred":"tao:has_database_id","subj":"252","obj":"MESH:C000657245"},{"id":"A253","pred":"tao:has_database_id","subj":"253","obj":"MESH:C531747"},{"id":"A254","pred":"tao:has_database_id","subj":"254","obj":"MESH:C000657245"},{"id":"A255","pred":"tao:has_database_id","subj":"255","obj":"MESH:D003711"},{"id":"A256","pred":"tao:has_database_id","subj":"256","obj":"MESH:D011782"},{"id":"A257","pred":"tao:has_database_id","subj":"257","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}

{"project":"LitCovid-sentences","denotations":[{"id":"T29","span":{"begin":0,"end":249},"obj":"Sentence"},{"id":"T30","span":{"begin":250,"end":356},"obj":"Sentence"},{"id":"T31","span":{"begin":357,"end":486},"obj":"Sentence"},{"id":"T32","span":{"begin":487,"end":553},"obj":"Sentence"},{"id":"T33","span":{"begin":554,"end":619},"obj":"Sentence"},{"id":"T34","span":{"begin":620,"end":696},"obj":"Sentence"},{"id":"T35","span":{"begin":697,"end":761},"obj":"Sentence"},{"id":"T36","span":{"begin":762,"end":811},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T45","span":{"begin":111,"end":135},"obj":"Phenotype"},{"id":"T46","span":{"begin":144,"end":156},"obj":"Phenotype"},{"id":"T47","span":{"begin":208,"end":213},"obj":"Phenotype"},{"id":"T48","span":{"begin":215,"end":222},"obj":"Phenotype"},{"id":"T49","span":{"begin":224,"end":231},"obj":"Phenotype"},{"id":"T50","span":{"begin":237,"end":248},"obj":"Phenotype"},{"id":"T51","span":{"begin":272,"end":287},"obj":"Phenotype"},{"id":"T52","span":{"begin":373,"end":388},"obj":"Phenotype"},{"id":"T53","span":{"begin":393,"end":407},"obj":"Phenotype"},{"id":"T54","span":{"begin":525,"end":538},"obj":"Phenotype"},{"id":"T55","span":{"begin":651,"end":662},"obj":"Phenotype"}],"attributes":[{"id":"A45","pred":"hp_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/HP_0007340"},{"id":"A46","pred":"hp_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/HP_0003401"},{"id":"A47","pred":"hp_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/HP_0012735"},{"id":"A48","pred":"hp_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/HP_0000458"},{"id":"A49","pred":"hp_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/HP_0041051"},{"id":"A50","pred":"hp_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/HP_0033050"},{"id":"A51","pred":"hp_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/HP_0001888"},{"id":"A52","pred":"hp_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/HP_0001349"},{"id":"A53","pred":"hp_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/HP_0010871"},{"id":"A54","pred":"hp_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/HP_0011096"},{"id":"A55","pred":"hp_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/HP_0002445"}],"text":"Italy has just reported 6 patients with GBS,8 1 in this issue.9 All presented with subacute onset of upper and lower extremity weakness, distal paresthesias, and sensory deficits 3–10 days after experiencing cough, anosmia, ageusia, and sore throat. On admission, all had lymphocytopenia and high C-reactive protein (CRP) that led to diagnosis of COVID-19. One patient had facial diplegia and sensory ataxia.8 The CSF showed elevated protein concentration but was negative for COVID-19. Electrophysiology was consistent with demyelinating or axonal GBS. MRI showed enhancement of the caudal nerve roots or facial nerve. Symptoms rapidly progressed to tetraplegia requiring mechanical ventilation. Antiganglioside antibodies in 3/6 tested patients were negative. All received IVIg with variable recovery; 1 died."}