PMC:7307149 / 7256-7977 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T49","span":{"begin":22,"end":25},"obj":"Body_part"},{"id":"T50","span":{"begin":178,"end":181},"obj":"Body_part"},{"id":"T51","span":{"begin":403,"end":406},"obj":"Body_part"}],"attributes":[{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma84795"}],"text":"FIG 1 Distribution of HLA allelic presentation of 8- to 12-mers from the SARS-CoV-2 proteome. At right, the number of peptides (see Table S1) that putatively bind to each of 145 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (\u003c50 nM) and loosely (\u003c500 nM) binding peptides, respectively, and with green, orange, and purple representing HLA-A, -B, and -C alleles, respectively. Alleles are sorted in descending order based on the number of peptides that they bind (\u003c500 nM). The corresponding estimated allelic frequency in the global population is also shown (left), with the length of each horizontal bar indicating absolute frequency in the population."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T52","span":{"begin":73,"end":81},"obj":"Disease"}],"attributes":[{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"FIG 1 Distribution of HLA allelic presentation of 8- to 12-mers from the SARS-CoV-2 proteome. At right, the number of peptides (see Table S1) that putatively bind to each of 145 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (\u003c50 nM) and loosely (\u003c500 nM) binding peptides, respectively, and with green, orange, and purple representing HLA-A, -B, and -C alleles, respectively. Alleles are sorted in descending order based on the number of peptides that they bind (\u003c500 nM). The corresponding estimated allelic frequency in the global population is also shown (left), with the length of each horizontal bar indicating absolute frequency in the population."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T74","span":{"begin":118,"end":126},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T75","span":{"begin":138,"end":140},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T76","span":{"begin":202,"end":203},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T77","span":{"begin":331,"end":339},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T78","span":{"begin":407,"end":408},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T79","span":{"begin":411,"end":412},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T80","span":{"begin":506,"end":514},"obj":"http://purl.obolibrary.org/obo/PR_000018263"}],"text":"FIG 1 Distribution of HLA allelic presentation of 8- to 12-mers from the SARS-CoV-2 proteome. At right, the number of peptides (see Table S1) that putatively bind to each of 145 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (\u003c50 nM) and loosely (\u003c500 nM) binding peptides, respectively, and with green, orange, and purple representing HLA-A, -B, and -C alleles, respectively. Alleles are sorted in descending order based on the number of peptides that they bind (\u003c500 nM). The corresponding estimated allelic frequency in the global population is also shown (left), with the length of each horizontal bar indicating absolute frequency in the population."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T21","span":{"begin":118,"end":126},"obj":"Chemical"},{"id":"T22","span":{"begin":331,"end":339},"obj":"Chemical"},{"id":"T23","span":{"begin":506,"end":514},"obj":"Chemical"}],"attributes":[{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A22","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A23","pred":"chebi_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"}],"text":"FIG 1 Distribution of HLA allelic presentation of 8- to 12-mers from the SARS-CoV-2 proteome. At right, the number of peptides (see Table S1) that putatively bind to each of 145 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (\u003c50 nM) and loosely (\u003c500 nM) binding peptides, respectively, and with green, orange, and purple representing HLA-A, -B, and -C alleles, respectively. Alleles are sorted in descending order based on the number of peptides that they bind (\u003c500 nM). The corresponding estimated allelic frequency in the global population is also shown (left), with the length of each horizontal bar indicating absolute frequency in the population."}

{"project":"LitCovid-PubTator","denotations":[{"id":"166","span":{"begin":403,"end":420},"obj":"Gene"},{"id":"167","span":{"begin":73,"end":83},"obj":"Species"}],"attributes":[{"id":"A166","pred":"tao:has_database_id","subj":"166","obj":"Gene:3105"},{"id":"A167","pred":"tao:has_database_id","subj":"167","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"FIG 1 Distribution of HLA allelic presentation of 8- to 12-mers from the SARS-CoV-2 proteome. At right, the number of peptides (see Table S1) that putatively bind to each of 145 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (\u003c50 nM) and loosely (\u003c500 nM) binding peptides, respectively, and with green, orange, and purple representing HLA-A, -B, and -C alleles, respectively. Alleles are sorted in descending order based on the number of peptides that they bind (\u003c500 nM). The corresponding estimated allelic frequency in the global population is also shown (left), with the length of each horizontal bar indicating absolute frequency in the population."}

{"project":"LitCovid-sentences","denotations":[{"id":"T49","span":{"begin":0,"end":93},"obj":"Sentence"},{"id":"T50","span":{"begin":94,"end":443},"obj":"Sentence"},{"id":"T51","span":{"begin":444,"end":540},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"FIG 1 Distribution of HLA allelic presentation of 8- to 12-mers from the SARS-CoV-2 proteome. At right, the number of peptides (see Table S1) that putatively bind to each of 145 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (\u003c50 nM) and loosely (\u003c500 nM) binding peptides, respectively, and with green, orange, and purple representing HLA-A, -B, and -C alleles, respectively. Alleles are sorted in descending order based on the number of peptides that they bind (\u003c500 nM). The corresponding estimated allelic frequency in the global population is also shown (left), with the length of each horizontal bar indicating absolute frequency in the population."}