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PMC:7306567 / 15375-16237 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
160 22-26 Chemical denotes IAPA
161 305-317 Chemical denotes Posaconazole MESH:C101425
162 64-73 Disease denotes pneumonia MESH:D011014
163 368-383 Disease denotes neutropenic AML MESH:D015470
164 408-433 Disease denotes graft-versus-host disease MESH:D006086
165 724-737 Disease denotes malabsorption MESH:D008286

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T74 54-63 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T75 64-73 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T76 285-287 Disease denotes IA http://purl.obolibrary.org/obo/MONDO_0000240
T77 362-364 Disease denotes IA http://purl.obolibrary.org/obo/MONDO_0000240
T78 380-383 Disease denotes AML http://purl.obolibrary.org/obo/MONDO_0018874
T79 408-433 Disease denotes graft-versus-host disease http://purl.obolibrary.org/obo/MONDO_0013730
T80 724-737 Disease denotes malabsorption http://purl.obolibrary.org/obo/MONDO_0020598

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T98 233-239 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T99 497-500 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T100 703-704 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 810-811 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T97 78-88 Chemical denotes antifungal http://purl.obolibrary.org/obo/CHEBI_35718
T98 240-256 Chemical denotes antifungal agent http://purl.obolibrary.org/obo/CHEBI_35718
T99 285-287 Chemical denotes IA http://purl.obolibrary.org/obo/CHEBI_74062
T100 362-364 Chemical denotes IA http://purl.obolibrary.org/obo/CHEBI_74062
T101 597-599 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T102 764-766 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T25 64-73 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T26 380-383 Phenotype denotes AML http://purl.obolibrary.org/obo/HP_0004808
T27 724-737 Phenotype denotes malabsorption http://purl.obolibrary.org/obo/HP_0002024

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T102 0-196 Sentence denotes In settings with high IAPA rates in ICU patients with influenza pneumonia, an antifungal prophylaxis strategy might be appropriate, particularly as IAPA typically occurs early after ICU admission.
T103 197-304 Sentence denotes However, there is currently no mold-active antifungal agent licensed for prophylaxis of IA in ICU patients.
T104 305-459 Sentence denotes Posaconazole (POS) prophylaxis reduces the prevalence of IA in neutropenic AML patients and those with graft-versus-host disease following alloHCT [2, 3].
T105 460-583 Sentence denotes Based on this proof-of-principle, it has been hypothesized that POS prophylaxis can reduce IAPA prevalence in ICU patients.
T106 584-759 Sentence denotes Intravenous (IV) administration of POS prophylaxis in the ICU is favored in patients on mechanical ventilation or with a high likelihood of malabsorption of oral formulations.
T107 760-862 Sentence denotes POS IV formulation should be administered through a central catheter due to its acidity (pH 3.2) [42].

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T118 305-317 CHEBI:64355;CHEBI:64355 denotes Posaconazole
T119 741-745 UBERON:0000165 denotes oral
T120 840-847 CHEBI:37527;CHEBI:37527 denotes acidity
T66121 305-317 CHEBI:64355;CHEBI:64355 denotes Posaconazole
T65652 741-745 UBERON:0000165 denotes oral
T18742 840-847 CHEBI:37527;CHEBI:37527 denotes acidity