PMC:7299399 / 65249-66675 JSON TXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T313","span":{"begin":78,"end":80},"obj":"Body_part"},{"id":"T314","span":{"begin":371,"end":376},"obj":"Body_part"},{"id":"T315","span":{"begin":440,"end":442},"obj":"Body_part"},{"id":"T316","span":{"begin":1418,"end":1422},"obj":"Body_part"}],"attributes":[{"id":"A313","pred":"fma_id","subj":"T313","obj":"http://purl.org/sig/ont/fma/fma61898"},{"id":"A314","pred":"fma_id","subj":"T314","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A315","pred":"fma_id","subj":"T315","obj":"http://purl.org/sig/ont/fma/fma61898"},{"id":"A316","pred":"fma_id","subj":"T316","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

LitCovid-PD-MONDO

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T194","span":{"begin":364,"end":370},"obj":"Disease"},{"id":"T195","span":{"begin":625,"end":628},"obj":"Disease"},{"id":"T196","span":{"begin":959,"end":967},"obj":"Disease"}],"attributes":[{"id":"A194","pred":"mondo_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"},{"id":"A195","pred":"mondo_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/MONDO_0012956"},{"id":"A196","pred":"mondo_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/MONDO_0005059"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

LitCovid-PD-CLO

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T556","span":{"begin":216,"end":217},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T557","span":{"begin":343,"end":344},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T558","span":{"begin":371,"end":376},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T559","span":{"begin":458,"end":460},"obj":"http://purl.obolibrary.org/obo/CLO_0008192"},{"id":"T560","span":{"begin":565,"end":572},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T561","span":{"begin":968,"end":973},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T562","span":{"begin":1046,"end":1053},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T563","span":{"begin":1318,"end":1323},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T564","span":{"begin":1324,"end":1332},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T565","span":{"begin":1379,"end":1384},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T566","span":{"begin":1418,"end":1422},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

LitCovid-PD-CHEBI

LitCovid-PD-HP

{"project":"LitCovid-PD-HP","denotations":[{"id":"T42","span":{"begin":364,"end":370},"obj":"Phenotype"},{"id":"T43","span":{"begin":959,"end":967},"obj":"Phenotype"}],"attributes":[{"id":"A42","pred":"hp_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/HP_0002664"},{"id":"A43","pred":"hp_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/HP_0001909"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

LitCovid-PD-GO-BP

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T75","span":{"begin":1163,"end":1177},"obj":"http://purl.obolibrary.org/obo/GO_1903409"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T252","span":{"begin":0,"end":447},"obj":"Sentence"},{"id":"T253","span":{"begin":448,"end":855},"obj":"Sentence"},{"id":"T254","span":{"begin":856,"end":1212},"obj":"Sentence"},{"id":"T255","span":{"begin":1213,"end":1426},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

LitCovid-PubTator

{"project":"LitCovid-PubTator","denotations":[{"id":"1019","span":{"begin":625,"end":628},"obj":"Gene"},{"id":"1020","span":{"begin":633,"end":638},"obj":"Species"},{"id":"1021","span":{"begin":952,"end":979},"obj":"Species"},{"id":"1022","span":{"begin":85,"end":87},"obj":"Chemical"},{"id":"1023","span":{"begin":540,"end":542},"obj":"Chemical"},{"id":"1024","span":{"begin":650,"end":652},"obj":"Chemical"},{"id":"1025","span":{"begin":926,"end":928},"obj":"Chemical"},{"id":"1026","span":{"begin":1035,"end":1037},"obj":"Chemical"},{"id":"1027","span":{"begin":1075,"end":1078},"obj":"Chemical"},{"id":"1028","span":{"begin":1163,"end":1166},"obj":"Chemical"},{"id":"1029","span":{"begin":364,"end":370},"obj":"Disease"}],"attributes":[{"id":"A1019","pred":"tao:has_database_id","subj":"1019","obj":"Gene:100271694"},{"id":"A1020","pred":"tao:has_database_id","subj":"1020","obj":"Tax:261665"},{"id":"A1021","pred":"tao:has_database_id","subj":"1021","obj":"Tax:11786"},{"id":"A1022","pred":"tao:has_database_id","subj":"1022","obj":"MESH:D006046"},{"id":"A1023","pred":"tao:has_database_id","subj":"1023","obj":"MESH:D006046"},{"id":"A1024","pred":"tao:has_database_id","subj":"1024","obj":"MESH:D006046"},{"id":"A1025","pred":"tao:has_database_id","subj":"1025","obj":"MESH:D006046"},{"id":"A1026","pred":"tao:has_database_id","subj":"1026","obj":"MESH:D006046"},{"id":"A1027","pred":"tao:has_database_id","subj":"1027","obj":"MESH:D017382"},{"id":"A1028","pred":"tao:has_database_id","subj":"1028","obj":"MESH:D017382"},{"id":"A1029","pred":"tao:has_database_id","subj":"1029","obj":"MESH:D009369"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

2_test

{"project":"2_test","denotations":[{"id":"32519842-29240431-158610","span":{"begin":712,"end":715},"obj":"29240431"},{"id":"32519842-28931903-158611","span":{"begin":980,"end":983},"obj":"28931903"},{"id":"32519842-28931903-158612","span":{"begin":1423,"end":1426},"obj":"28931903"}],"text":"Another example of the use of noble metals for disinfection is the ability of Ag and Au NPs and nanorods to induce heating when illuminated at optimal wavelength, corresponding to the plasmon resonance condition, in a process called plasmonic photothermal treatment.188 This property is currently being evaluated by nanomedical researchers as a method for killing cancer cells with Au NPs because Au NPs are considered much less toxic than Ag NPs. By tuning NP size and shape, it is possible to emit intense heat under solar irradiation of Au NPs and to inactivate viruses, as demonstrated by Loeb et al. with bacteriophages MS2 and PR772 exposed to Au nanorods and nanocubes or to surfaces coated with such NPs.189 Close contact between NPs and the pathogen is necessary for the process to be effective, which supposes that NPs adsorb onto their surface. Elsewhere, Nazari et al. used femtosecond pulsed laser irradiation on Au nanorods to inactivate murine leukemia virus (MLV).190 Here, inactivation did not require contact between Au NRs and viruses, and the addition of ROS scavengers did not reduce the inactivation effect, suggesting that neither heat nor ROS generation accounted for the observed effect. The authors propose that the underlying mechanism is plasmon-enhanced shockwave generation, which alters virus membrane and/or surface groups and, therefore, reduces virus binding and fusion with the host cell.190"}

PMC:7299399 / 65249-66675 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:7299399 / 65249-66675 JSON TXT