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PMC:7299399 / 60311-62228 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T298 798-804 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T299 1019-1027 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T300 1441-1449 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T301 1505-1513 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T302 1742-1744 Body_part denotes Ag http://purl.org/sig/ont/fma/fma61898
T303 1760-1762 Body_part denotes Ag http://purl.org/sig/ont/fma/fma61898
T304 1773-1775 Body_part denotes Ag http://purl.org/sig/ont/fma/fma61898

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T178 448-456 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T179 518-528 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T180 1181-1189 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T181 1196-1204 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T182 1815-1823 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T529 18-26 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T530 33-36 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T531 101-102 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T22037 175-182 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T533 1281-1283 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T534 1824-1829 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T82354 4-17 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T82509 30-32 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T88740 125-127 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T27795 221-223 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T160 286-288 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T161 358-360 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T162 555-561 Chemical denotes Teflon http://purl.obolibrary.org/obo/CHEBI_53251
T16026 563-581 Chemical denotes polyvinyl chloride http://purl.obolibrary.org/obo/CHEBI_53243
T35768 573-581 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T33349 696-698 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T42035 702-704 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T95397 705-707 Chemical denotes Ni http://purl.obolibrary.org/obo/CHEBI_28112
T25989 739-741 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T23485 764-766 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T60768 951-953 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T171 954-958 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T34651 977-979 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T16287 1019-1027 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T87032 1032-1038 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T175 1042-1045 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T176 1061-1063 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T94767 1088-1096 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T44100 1100-1116 Chemical denotes molecular oxygen http://purl.obolibrary.org/obo/CHEBI_15379
T60680 1110-1116 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T56113 1226-1228 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T94819 1441-1449 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T67332 1454-1460 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T9429 1464-1466 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T27159 1467-1471 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T185 1476-1479 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T6977 1505-1513 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T34749 1524-1526 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T14818 1538-1540 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T77608 1611-1624 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T190 1719-1724 Chemical denotes Al2O3 http://purl.obolibrary.org/obo/CHEBI_30187
T86216 1742-1744 Chemical denotes Ag http://purl.obolibrary.org/obo/CHEBI_30512|http://purl.obolibrary.org/obo/CHEBI_9141
T6452 1749-1751 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T95144 1760-1762 Chemical denotes Ag http://purl.obolibrary.org/obo/CHEBI_30512|http://purl.obolibrary.org/obo/CHEBI_9141
T196 1763-1768 Chemical denotes Al2O3 http://purl.obolibrary.org/obo/CHEBI_30187
T197 1773-1775 Chemical denotes Ag http://purl.obolibrary.org/obo/CHEBI_30512|http://purl.obolibrary.org/obo/CHEBI_9141
T92899 1781-1783 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T70914 1784-1789 Chemical denotes Al2O3 http://purl.obolibrary.org/obo/CHEBI_30187
T85524 1795-1797 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T238 0-183 Sentence denotes The antimicrobial activity of Cu has also been known since ancient times,166 and surfaces containing a significant amount of Cu have demonstrated their efficacy to inactivate viruses.
T239 184-1686 Sentence denotes Murray et al. showed the efficacy of Cu against poliovirus in 1979.167 More recently, the efficacy of Cu was demonstrated on the HuCoV-229E coronavirus; the effectiveness of Cu to inactivate other forms of coronaviruses suggests potential similar efficacy against SARS-CoV-2.168 Whereas HuCoV-229E persists for more than 6 days in an infectious state on smooth surfaces (Teflon, polyvinyl chloride, ceramic tiles, glass, stainless steel), it is inactivated in less than 60 min on brasses containing at least 70% Cu or Cu–Ni alloys containing at least 90% Cu.168 When incubated on Cu-containing surfaces, the viral genome becomes fragmented, ensuring the irreversibility of inactivation.168 The proposed inactivation mechanisms include both toxicity toward virions of Cu ions released from the Cu-containing surface and attack of viral proteins and lipids by ROS generated from Cu reacting with exogenous hydrogen or molecular oxygen through Fenton-like or Haber Weiss reactions.166 Likewise, both SARS-CoV-1 and SARS-CoV-2 are inactivated on Cu surfaces in less than 4 h, whereas they persist for 48–72 h on plastic and stainless steel and less than 24 h on cardboard.153 In this case, the main inactivation mechanism is also proposed to be damage to viral proteins and lipids by Cu ions and ROS, in particular, envelope proteins.153 Using Cu brasses or Cu-containing alloys rather than stainless steel would provide effective antimicrobial surfaces (doorknobs, bed rails, etc.) in healthcare settings.
T240 1687-1917 Sentence denotes Supported catalysts composed of Al2O3 impregnated with Ag and Cu to form Ag/Al2O3 (5% Ag) and Cu/Al2O3 (10% Cu) also inactivate SARS-CoV virus in less than 5 and 20 min, respectively, which would be useful for air disinfection.169

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
903 232-242 Species denotes poliovirus Tax:138950
904 390-403 Species denotes coronaviruses Tax:11118
905 448-458 Species denotes SARS-CoV-2 Tax:2697049
906 1181-1189 Species denotes SARS-CoV Tax:694009
907 1196-1206 Species denotes SARS-CoV-2 Tax:2697049
908 1815-1823 Species denotes SARS-CoV Tax:694009
909 319-323 Species denotes 229E Tax:11137
910 477-481 Species denotes 229E Tax:11137
911 324-335 Species denotes coronavirus Tax:11118
912 30-32 Chemical denotes Cu MESH:D003300
913 125-127 Chemical denotes Cu MESH:D003300
914 221-223 Chemical denotes Cu MESH:D003300
915 286-288 Chemical denotes Cu MESH:D003300
916 358-360 Chemical denotes Cu MESH:D003300
917 563-581 Chemical denotes polyvinyl chloride MESH:D011143
918 696-698 Chemical denotes Cu MESH:D003300
919 739-741 Chemical denotes Cu MESH:D003300
920 764-766 Chemical denotes Cu MESH:D003300
921 951-953 Chemical denotes Cu MESH:D003300
922 977-979 Chemical denotes Cu MESH:D003300
923 1032-1038 Chemical denotes lipids MESH:D008055
924 1042-1045 Chemical denotes ROS MESH:D017382
925 1061-1063 Chemical denotes Cu MESH:D003300
926 1088-1096 Chemical denotes hydrogen MESH:D006859
927 1110-1116 Chemical denotes oxygen MESH:D010100
928 1226-1228 Chemical denotes Cu MESH:D003300
929 1454-1460 Chemical denotes lipids MESH:D008055
930 1464-1466 Chemical denotes Cu MESH:D003300
931 1476-1479 Chemical denotes ROS MESH:D017382
932 1524-1526 Chemical denotes Cu MESH:D003300
933 1538-1540 Chemical denotes Cu MESH:D003300
934 1571-1586 Chemical denotes stainless steel MESH:D013193
935 1719-1724 Chemical denotes Al2O3
936 1749-1751 Chemical denotes Cu MESH:D003300
937 1763-1768 Chemical denotes Al2O3
938 1781-1783 Chemical denotes Cu MESH:D003300
939 1784-1789 Chemical denotes Al2O3
940 1795-1797 Chemical denotes Cu MESH:D003300
941 924-932 Disease denotes toxicity MESH:D064420

2_test

Id Subject Object Predicate Lexical cue
32519842-21193661-158592 73-76 21193661 denotes 166
32519842-222209-158593 251-254 222209 denotes 167
32519842-21193661-158594 1162-1165 21193661 denotes 166
32519842-32182409-158595 1352-1355 32182409 denotes 153
32519842-32182409-158596 1514-1517 32182409 denotes 153
32519842-16131020-158597 1914-1917 16131020 denotes 169