PMC:7299399 / 34714-35773
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T173 | 189-194 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T174 | 454-458 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T175 | 693-701 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T176 | 1032-1038 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T47 | 1032-1038 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T129 | 130-138 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T130 | 217-231 | Disease | denotes | photosensitive | http://purl.obolibrary.org/obo/MONDO_0006598 |
| T131 | 848-862 | Disease | denotes | herpes simplex | http://purl.obolibrary.org/obo/MONDO_0004609 |
| T132 | 876-885 | Disease | denotes | papilloma | http://purl.obolibrary.org/obo/MONDO_0002363 |
| T133 | 903-919 | Disease | denotes | immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T314 | 98-99 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T315 | 148-149 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T316 | 189-194 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T317 | 303-304 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T318 | 454-458 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T319 | 639-646 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T320 | 687-692 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T321 | 829-836 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T322 | 863-868 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T323 | 870-875 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T324 | 886-891 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T325 | 897-902 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T326 | 920-925 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T247 | 15-19 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T248 | 39-48 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T249 | 83-86 | Chemical | denotes | PDT | http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622 |
| T251 | 170-173 | Chemical | denotes | PDT | http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622 |
| T253 | 369-392 | Chemical | denotes | reactive oxygen species | http://purl.obolibrary.org/obo/CHEBI_26523 |
| T254 | 378-384 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T255 | 394-397 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
| T256 | 418-424 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T257 | 601-604 | Chemical | denotes | PDT | http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622 |
| T259 | 662-665 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
| T260 | 693-701 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T261 | 703-716 | Chemical | denotes | nucleic acids | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T262 | 711-716 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T263 | 733-739 | Chemical | denotes | lipids | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T264 | 787-790 | Chemical | denotes | PDT | http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622 |
| T266 | 950-953 | Chemical | denotes | PDT | http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T32 | 217-231 | Phenotype | denotes | photosensitive | http://purl.obolibrary.org/obo/HP_0000992 |
| T33 | 876-885 | Phenotype | denotes | papilloma | http://purl.obolibrary.org/obo/HP_0012740 |
| T34 | 903-919 | Phenotype | denotes | immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T55 | 454-464 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | cell death |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T134 | 0-141 | Sentence | denotes | In addition to drug- and vaccine-based antiviral strategies, photodynamic therapy (PDT) stands as a unique approach to inactivate SARS-CoV-2. |
| T135 | 142-465 | Sentence | denotes | Using a light-based method, PDT attacks target cells via the excitation of photosensitive agents, called photosensitizers (PSs), with radiation characterized by a wavelength corresponding to its absorption spectrum to generate reactive oxygen species (ROS) in the presence of oxygen, which ultimately results in cell death. |
| T136 | 466-1059 | Sentence | denotes | Photodynamic therapy is primarily used for the clinical treatment of various oncological disorders.105 It was not until the 1970s that PDT was first used clinically against viruses,106 exploiting ROS production to damage virus proteins, nucleic acids, and—if present—lipids.107 Even though there are research efforts for PDT-based virotherapies against different viruses, including herpes simplex virus, human papilloma virus, and human immunodeficiency virus,106−109 clinical use of PDT is limited due to hydrophobicity of PSs, poor target specificity, and limited tissue penetration ability. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 575 | 130-140 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 576 | 870-891 | Species | denotes | human papilloma virus | Tax:10566 |
| 577 | 897-925 | Species | denotes | human immunodeficiency virus | Tax:12721 |
| 578 | 369-392 | Chemical | denotes | reactive oxygen species | MESH:D017382 |
| 579 | 394-397 | Chemical | denotes | ROS | MESH:D017382 |
| 580 | 418-424 | Chemical | denotes | oxygen | MESH:D010100 |
| 581 | 662-665 | Chemical | denotes | ROS | MESH:D017382 |
| 582 | 733-739 | Chemical | denotes | lipids | MESH:D008055 |
| 583 | 459-464 | Disease | denotes | death | MESH:D003643 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32519842-21617154-158527 | 565-568 | 21617154 | denotes | 105 |
| 32519842-12791463-158528 | 647-650 | 12791463 | denotes | 106 |
| 32519842-31397467-158529 | 740-743 | 31397467 | denotes | 107 |
| 32519842-12791463-158530 | 926-929 | 12791463 | denotes | 106 |
| 32519842-22852040-158531 | 930-933 | 22852040 | denotes | 109 |