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PMC:7299399 / 11390-49391 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T46 95-112 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T47 129-133 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T48 190-193 Body_part denotes gut http://purl.org/sig/ont/fma/fma7199
T49 195-201 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T50 319-326 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T51 393-397 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T52 430-435 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T53 526-530 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T54 564-569 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T55 630-638 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T56 658-663 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T57 758-763 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T58 836-840 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T59 857-861 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T60 975-979 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T61 1212-1220 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T62 2058-2087 Body_part denotes heparan sulfate proteoglycans http://purl.org/sig/ont/fma/fma82834
T63 2058-2073 Body_part denotes heparan sulfate http://purl.org/sig/ont/fma/fma63023
T64 2089-2093 Body_part denotes HSPG http://purl.org/sig/ont/fma/fma82834
T65 2126-2130 Body_part denotes HSPG http://purl.org/sig/ont/fma/fma82834
T66 2225-2239 Body_part denotes cell membranes http://purl.org/sig/ont/fma/fma63841
T67 2225-2229 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T68 3067-3074 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T69 5037-5050 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T70 5484-5492 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T71 5558-5561 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T72 5566-5569 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T73 5645-5653 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T74 5684-5691 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T75 5781-5788 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T76 5860-5867 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T77 5962-5969 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T78 5974-5977 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T79 6221-6226 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T80 6334-6342 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T81 6383-6390 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T82 6690-6695 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T83 6700-6705 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T84 6795-6803 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T85 7498-7502 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T86 7532-7540 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T87 7559-7566 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T88 7820-7825 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T89 8146-8150 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T90 8160-8164 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T91 8187-8192 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T92 8606-8609 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T93 9168-9175 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T94 9556-9561 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T95 9625-9629 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T96 9940-9947 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T97 10079-10082 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T98 10087-10091 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T99 10309-10313 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T100 10511-10515 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T101 10530-10538 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T102 10926-10933 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T103 10969-10976 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T104 12024-12027 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T105 12283-12290 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T106 12794-12801 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T107 13870-13875 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T108 14350-14363 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T109 14803-14816 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T110 14986-14995 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T111 15002-15007 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T112 15042-15046 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T113 15069-15079 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T114 16116-16123 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T115 16177-16189 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T116 17065-17069 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T117 17065-17067 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T118 17074-17085 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T119 17183-17191 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T120 17195-17206 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T121 18142-18150 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T122 18218-18226 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T123 18240-18244 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T124 18260-18268 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T125 18546-18551 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T126 18653-18664 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T127 18666-18668 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T128 18806-18808 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T129 18833-18835 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T130 18847-18855 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T131 18875-18877 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T132 18926-18934 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T133 19128-19132 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T134 19205-19213 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T135 19382-19390 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T136 19501-19506 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T137 19580-19587 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T138 19688-19701 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T139 20054-20065 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T140 20123-20134 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T141 20215-20217 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T142 20245-20251 Body_part denotes spleen http://purl.org/sig/ont/fma/fma7196
T143 20256-20267 Body_part denotes lymph nodes http://purl.org/sig/ont/fma/fma5034
T144 20256-20261 Body_part denotes lymph http://purl.org/sig/ont/fma/fma9671
T145 20336-20347 Body_part denotes lymph nodes http://purl.org/sig/ont/fma/fma5034
T146 20336-20341 Body_part denotes lymph http://purl.org/sig/ont/fma/fma9671
T147 20352-20358 Body_part denotes spleen http://purl.org/sig/ont/fma/fma7196
T148 20359-20365 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T149 20431-20442 Body_part denotes lymphocytic http://purl.org/sig/ont/fma/fma62863
T150 20458-20465 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T151 20564-20575 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T152 20642-20652 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T153 20775-20783 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T154 20812-20822 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T155 20827-20835 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T156 20850-20854 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T157 20855-20866 Body_part denotes capillaries http://purl.org/sig/ont/fma/fma63194
T158 21179-21183 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T159 21342-21353 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T160 21426-21436 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T161 21714-21727 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T162 22149-22153 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T163 22276-22285 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T164 22408-22417 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T165 22423-22428 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T166 22568-22573 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T167 22677-22686 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T168 22698-22700 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T169 22847-22856 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T170 22862-22867 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T171 23082-23091 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T172 23252-23262 Body_part denotes human body http://purl.org/sig/ont/fma/fma305853
T173 23513-23518 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T174 23778-23782 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T175 24017-24025 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T176 24356-24362 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T177 26135-26138 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T178 27013-27017 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T179 27067-27074 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T180 27211-27215 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T181 27335-27344 Body_part denotes epithelia http://purl.org/sig/ont/fma/fma9639
T182 27454-27458 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T183 27567-27571 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T184 27583-27589 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T185 27593-27604 Body_part denotes body region http://purl.org/sig/ont/fma/fma7153
T186 27776-27783 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T187 27908-27916 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T188 27995-27999 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T189 29192-29196 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T190 29331-29335 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T191 29345-29350 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T192 29708-29716 Body_part denotes backbone http://purl.org/sig/ont/fma/fma13478
T193 29786-29790 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T194 30445-30449 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T195 30856-30860 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T196 31506-31514 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T197 31928-31933 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T198 32146-32150 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T199 32550-32558 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T200 32581-32586 Body_part denotes sugar http://purl.org/sig/ont/fma/fma82737
T201 32628-32638 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T202 32671-32689 Body_part denotes glycosaminoglycans http://purl.org/sig/ont/fma/fma63011
T203 32691-32695 Body_part denotes GAGs http://purl.org/sig/ont/fma/fma63011
T204 32700-32715 Body_part denotes heparan sulfate http://purl.org/sig/ont/fma/fma63023
T205 32717-32719 Body_part denotes HS http://purl.org/sig/ont/fma/fma63023
T206 33031-33035 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T207 33148-33160 Body_part denotes cell-surface http://purl.org/sig/ont/fma/fma67653
T208 33148-33152 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T209 33170-33185 Body_part denotes heparan sulfate http://purl.org/sig/ont/fma/fma63023
T210 33311-33315 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T211 33489-33494 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T212 33750-33755 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T213 33805-33812 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T214 33845-33858 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T215 33845-33849 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T216 34018-34020 Body_part denotes HS http://purl.org/sig/ont/fma/fma63023
T217 34125-34129 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T218 34357-34364 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T219 34650-34657 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T220 36561-36569 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T221 36591-36596 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T222 37032-37037 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T223 37047-37052 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T224 37412-37427 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T225 37496-37501 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T15 95-112 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T16 129-133 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T17 153-159 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T18 195-201 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T19 393-397 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T20 430-435 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T21 526-530 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T22 836-840 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T23 857-861 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T24 975-979 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T25 1062-1067 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T26 5037-5050 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T27 9625-9629 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T28 14350-14363 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T29 14803-14816 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T30 18546-18551 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T31 19592-19598 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T32 19688-19701 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T33 20245-20251 Body_part denotes spleen http://purl.obolibrary.org/obo/UBERON_0002106
T34 20256-20267 Body_part denotes lymph nodes http://purl.obolibrary.org/obo/UBERON_0000029
T35 20256-20261 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391
T36 20336-20347 Body_part denotes lymph nodes http://purl.obolibrary.org/obo/UBERON_0000029
T37 20336-20341 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391
T38 20352-20358 Body_part denotes spleen http://purl.obolibrary.org/obo/UBERON_0002106
T39 20359-20365 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T40 20784-20791 Body_part denotes exudate http://purl.obolibrary.org/obo/UBERON_0007780
T41 20850-20854 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T42 21714-21727 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T43 22423-22428 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T44 22568-22573 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T45 22862-22867 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T46 22933-22937 Body_part denotes pore http://purl.obolibrary.org/obo/UBERON_0008915
T47 24356-24362 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T48 27079-27085 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T49 27335-27344 Body_part denotes epithelia http://purl.obolibrary.org/obo/UBERON_0000483
T50 27567-27571 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T51 27583-27589 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T52 31928-31933 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T53 34125-34129 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T57 35-43 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 77-85 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 1320-1328 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T60 1811-1819 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T61 2993-3001 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 3846-3854 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T63 4169-4175 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T64 4316-4326 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T65 4453-4461 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 4560-4568 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T67 4817-4825 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 7448-7463 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T69 7454-7463 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T70 7521-7529 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 7718-7723 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T72 8860-8868 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T73 9151-9159 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T74 9398-9406 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T75 9444-9454 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T76 9598-9617 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T77 9923-9931 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 9949-9952 Disease denotes Ad5 http://purl.obolibrary.org/obo/MONDO_0011194
T79 11045-11055 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T80 11220-11228 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T81 12146-12155 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T82 12236-12244 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 12415-12423 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T84 12658-12677 Disease denotes immune dysfunctions http://purl.obolibrary.org/obo/MONDO_0005046
T85 12705-12713 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T86 12995-13002 Disease denotes tetanus http://purl.obolibrary.org/obo/MONDO_0005526
T87 13007-13017 Disease denotes diphtheria http://purl.obolibrary.org/obo/MONDO_0005504
T88 13227-13236 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T89 13317-13332 Disease denotes avian influenza http://purl.obolibrary.org/obo/MONDO_0018695
T90 13323-13332 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T91 13454-13469 Disease denotes avian influenza http://purl.obolibrary.org/obo/MONDO_0018695
T92 13460-13469 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T93 13589-13598 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T94 13742-13755 Disease denotes herpes zoster http://purl.obolibrary.org/obo/MONDO_0005609
T95 14012-14023 Disease denotes hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T96 14012-14021 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T97 14034-14043 Disease denotes papilloma http://purl.obolibrary.org/obo/MONDO_0002363
T98 14503-14511 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T99 15366-15374 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T100 15475-15484 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T101 15513-15521 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 16105-16113 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T103 16166-16174 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T104 16426-16434 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T105 17671-17679 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T106 17772-17780 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T107 17906-17922 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T108 18040-18048 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T109 18186-18194 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T110 18287-18290 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T112 18464-18499 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T113 18470-18499 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T114 18501-18505 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T115 18537-18559 Disease denotes multiple-organ failure http://purl.obolibrary.org/obo/MONDO_0043726
T116 19042-19051 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T117 20069-20077 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T118 20146-20154 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 20413-20421 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 20478-20486 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T121 20605-20617 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T122 20744-20752 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 21503-21508 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T124 21798-21818 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T125 21934-21954 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T126 23108-23111 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T128 23313-23321 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T129 23454-23462 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T130 23541-23555 Disease denotes photosensitive http://purl.obolibrary.org/obo/MONDO_0006598
T131 24172-24186 Disease denotes herpes simplex http://purl.obolibrary.org/obo/MONDO_0004609
T132 24200-24209 Disease denotes papilloma http://purl.obolibrary.org/obo/MONDO_0002363
T133 24227-24243 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T134 24922-24928 Disease denotes Dengue http://purl.obolibrary.org/obo/MONDO_0005502
T135 26094-26114 Disease denotes vesicular stomatitis http://purl.obolibrary.org/obo/MONDO_0025028
T136 26104-26114 Disease denotes stomatitis http://purl.obolibrary.org/obo/MONDO_0004842
T137 26173-26182 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T138 26467-26473 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T139 26587-26595 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T140 33124-33133 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T141 33431-33441 Disease denotes stomatitis http://purl.obolibrary.org/obo/MONDO_0004842
T142 33720-33729 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T143 34130-34139 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T144 34368-34376 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T145 34955-34963 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T146 36425-36433 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 37041-37046 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T148 37490-37495 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T149 37990-37998 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T106 120-127 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T107 129-133 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T108 129-133 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T109 135-137 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T110 153-159 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T111 190-193 http://purl.obolibrary.org/obo/UBERON_0001007 denotes gut
T112 190-193 http://purl.obolibrary.org/obo/UBERON_0001555 denotes gut
T113 190-193 http://www.ebi.ac.uk/efo/EFO_0000834 denotes gut
T114 195-201 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T115 195-201 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T116 195-201 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T117 240-241 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T118 393-397 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T119 393-397 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T120 430-435 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T121 508-513 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T122 526-530 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T123 526-530 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T124 564-569 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T125 593-598 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T126 639-649 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T127 658-663 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T128 722-723 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T129 758-763 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T130 773-774 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 792-797 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T132 836-840 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T133 836-840 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T134 857-861 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T135 857-861 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T136 975-979 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T137 975-979 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T138 1118-1125 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T139 1158-1166 http://purl.obolibrary.org/obo/CLO_0001658 denotes actively
T140 1331-1334 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T141 1475-1476 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T142 1529-1534 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T143 1557-1558 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T144 1563-1568 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T145 1672-1679 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T146 1792-1799 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T147 1931-1932 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T148 1958-1965 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T149 1992-1995 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T150 2024-2031 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T151 2039-2042 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T152 2058-2087 http://purl.obolibrary.org/obo/PR_000001307 denotes heparan sulfate proteoglycans
T153 2089-2093 http://purl.obolibrary.org/obo/PR_000001307 denotes HSPG
T154 2126-2130 http://purl.obolibrary.org/obo/PR_000001307 denotes HSPG
T155 2184-2191 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T156 2225-2229 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T157 2230-2239 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T158 2254-2255 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 2275-2277 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T160 2445-2447 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T161 2489-2492 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T162 2577-2582 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T163 2620-2627 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T164 2682-2685 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T165 2885-2886 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T166 2938-2943 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T167 2974-2975 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 3002-3006 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2, a
T169 4141-4144 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T170 4475-4477 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T171 4542-4543 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T172 4692-4697 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T173 4794-4796 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T174 4873-4876 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T175 5037-5050 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T176 5376-5377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T177 5548-5553 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T178 5594-5596 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T179 5693-5695 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T180 5763-5765 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T181 5778-5780 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T182 5894-5895 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T183 5954-5955 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T184 6514-6515 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T185 6859-6864 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T186 6886-6891 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T187 6936-6939 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T188 7270-7271 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T189 7328-7333 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T190 7820-7825 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T191 7868-7869 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 7983-7984 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 8110-8111 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 8135-8142 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T195 8197-8198 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T196 8325-8327 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T197 8604-8605 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T198 8663-8666 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T199 8704-8715 http://purl.obolibrary.org/obo/NCBITaxon_10141 denotes guinea pigs
T200 8729-8730 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T201 8789-8792 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T202 8809-8816 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T203 8820-8826 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T204 9094-9095 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 9096-9106 http://purl.obolibrary.org/obo/NCBITaxon_9598 denotes chimpanzee
T206 9177-9187 http://purl.obolibrary.org/obo/NCBITaxon_9598 denotes Chimpanzee
T207 9253-9259 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T208 9328-9331 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T209 9357-9372 http://purl.obolibrary.org/obo/NCBITaxon_9544 denotes rhesus macaques
T210 9517-9522 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T211 9556-9561 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T212 9625-9629 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T213 9625-9629 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T214 9657-9664 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T215 9679-9680 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T216 9836-9837 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T217 9978-9984 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T218 10227-10233 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T219 10258-10261 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T220 10357-10364 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T221 10402-10403 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T222 10459-10466 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T223 10484-10486 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T224 10795-10796 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T225 11133-11135 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T226 11402-11408 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T227 11412-11413 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T228 11455-11456 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T229 11553-11556 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T230 11594-11601 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T231 11622-11623 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T232 11783-11798 http://purl.obolibrary.org/obo/NCBITaxon_9544 denotes rhesus macaques
T233 11813-11814 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T234 11851-11853 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T235 11877-11883 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T236 12051-12056 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T237 12114-12115 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T238 12716-12719 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T239 12720-12721 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T240 12880-12881 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T241 12932-12933 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T242 13042-13043 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T243 13423-13424 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T244 13561-13562 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T245 13766-13767 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T246 13876-13877 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T247 13884-13885 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T248 13941-13950 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T249 14022-14023 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T250 14028-14033 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T251 14044-14049 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T252 14070-14071 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T253 14350-14363 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T254 14790-14798 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T255 14803-14816 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T256 14937-14947 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T257 14973-14982 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T258 14986-14995 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T259 15000-15007 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T260 15040-15046 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T261 15083-15085 http://purl.obolibrary.org/obo/CLO_0007448 denotes M1
T262 15083-15085 http://purl.obolibrary.org/obo/CLO_0050175 denotes M1
T263 15268-15271 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T264 15333-15342 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T265 15428-15429 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T266 15750-15751 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T267 15982-15985 http://purl.obolibrary.org/obo/NCBITaxon_9793 denotes ASs
T268 16140-16141 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T269 16298-16305 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T270 16708-16714 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T271 16832-16835 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T272 16925-16934 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T273 17139-17144 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T274 17348-17350 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T275 17724-17725 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T276 17930-17935 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T277 18216-18217 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T278 18546-18551 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T279 18672-18675 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T280 18765-18772 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T281 18909-18910 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T282 19501-19506 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T283 19592-19598 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T284 19688-19701 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T285 19906-19907 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T286 19993-20001 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T287 20111-20115 http://purl.obolibrary.org/obo/PR_000002064 denotes CD68
T288 20245-20251 http://purl.obolibrary.org/obo/UBERON_0002106 denotes spleen
T289 20256-20267 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
T290 20336-20347 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
T291 20352-20358 http://purl.obolibrary.org/obo/UBERON_0002106 denotes spleen
T292 20546-20547 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T293 20623-20633 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T294 20827-20835 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T295 20850-20854 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T296 20850-20854 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T297 21179-21183 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T298 21336-21341 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T299 21367-21368 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T300 21714-21727 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T301 21886-21889 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T302 21972-21981 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T303 21972-21981 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T304 22131-22132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T305 22149-22153 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T306 22178-22179 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T307 22307-22310 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T308 22568-22573 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T309 22568-22573 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T310 22862-22867 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T311 22862-22867 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T312 23252-23257 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T313 23276-23281 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T314 23422-23423 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T315 23472-23473 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T316 23513-23518 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T317 23627-23628 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T318 23778-23782 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T319 23963-23970 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T320 24011-24016 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T321 24153-24160 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T322 24187-24192 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T323 24194-24199 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T324 24210-24215 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T325 24221-24226 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T326 24244-24249 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T327 24556-24557 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T328 24610-24617 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T329 24905-24913 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T330 24929-24934 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T331 25026-25033 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T332 25070-25071 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T333 25308-25310 http://purl.obolibrary.org/obo/CLO_0007815 denotes Mo
T334 25395-25397 http://purl.obolibrary.org/obo/CLO_0052906 denotes Cl
T335 26000-26005 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T336 26081-26086 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T337 26115-26120 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T338 26142-26150 http://purl.obolibrary.org/obo/NCBITaxon_7157 denotes mosquito
T339 26183-26184 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T340 26185-26190 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T341 26680-26687 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Viruses
T342 27079-27085 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T343 27223-27225 http://purl.obolibrary.org/obo/CLO_0008192 denotes NP
T344 27251-27256 http://purl.obolibrary.org/obo/UBERON_0001456 denotes faces
T345 27418-27425 http://purl.obolibrary.org/obo/OBI_0100026 denotes organic
T346 27418-27425 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organic
T347 27508-27509 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T348 27567-27571 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T349 27644-27651 http://purl.obolibrary.org/obo/OBI_0100026 denotes organic
T350 27644-27651 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organic
T351 27977-27982 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T352 27995-27999 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T353 28320-28321 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T354 28337-28340 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T355 28376-28377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T356 28515-28518 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T357 28570-28571 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T358 28590-28593 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T359 28666-28667 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T360 28845-28850 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T361 29036-29039 http://purl.obolibrary.org/obo/CLO_0001053 denotes 121
T362 29058-29063 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T363 29192-29196 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T364 29253-29260 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T365 29285-29291 http://purl.obolibrary.org/obo/NCBITaxon_9796 denotes horses
T366 29331-29335 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T367 29345-29350 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T368 29408-29413 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T369 29454-29455 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T370 29496-29502 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T371 29633-29634 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T372 29671-29678 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T373 29786-29790 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T374 29857-29858 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T375 29996-29997 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T376 30070-30071 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T377 30164-30165 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T378 30176-30182 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T379 30235-30236 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T380 30336-30337 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T381 30435-30441 http://purl.obolibrary.org/obo/UBERON_0007688 denotes fields
T382 30445-30449 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T383 30556-30559 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T384 30599-30605 http://purl.obolibrary.org/obo/UBERON_0007688 denotes fields
T385 30714-30721 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T386 30856-30860 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T387 31497-31505 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T388 31515-31518 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T389 31536-31537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T390 31671-31678 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T391 31727-31728 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T392 31842-31847 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T393 31856-31861 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T394 31888-31893 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T395 31928-31933 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T396 31928-31933 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T397 32120-32125 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T398 32146-32150 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T399 32189-32190 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T400 32221-32222 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T401 32362-32363 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T402 32458-32465 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T403 32761-32766 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T404 33011-33018 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T405 33031-33035 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T406 33148-33152 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T407 33228-33233 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T408 33285-33290 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T409 33311-33315 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T410 33397-33402 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T411 33442-33447 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T412 33489-33494 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T413 33730-33735 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T414 33750-33755 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T415 33845-33849 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T416 33850-33858 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T417 33863-33864 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T418 34055-34062 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T419 34093-34098 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T420 34123-34124 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T421 34125-34129 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T422 34125-34129 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T423 34354-34356 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T424 34647-34649 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T425 34703-34708 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T426 34770-34771 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T427 35027-35028 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T428 35891-35892 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T429 35985-35991 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T430 36473-36476 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T431 36591-36596 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T432 36713-36715 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T433 37032-37037 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T434 37047-37052 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T435 37198-37199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T436 37235-37237 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T437 37412-37418 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T438 37419-37427 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T439 37496-37501 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T440 37956-37958 http://purl.obolibrary.org/obo/CLO_0008192 denotes NP

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T50 574-578 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T51 655-657 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T52 1193-1198 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T53 1212-1220 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T54 1431-1446 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T55 1431-1440 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T56 1441-1446 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T57 1497-1507 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T58 1717-1722 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T59 1914-1924 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T60 1984-1990 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T61 2058-2073 Chemical denotes heparan sulfate http://purl.obolibrary.org/obo/CHEBI_28815
T62 2058-2065 Chemical denotes heparan http://purl.obolibrary.org/obo/CHEBI_24500
T63 2066-2073 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T64 2074-2087 Chemical denotes proteoglycans http://purl.obolibrary.org/obo/CHEBI_37396
T65 2100-2112 Chemical denotes sialic acids http://purl.obolibrary.org/obo/CHEBI_26667
T66 2107-2112 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T67 2114-2116 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T72 2135-2137 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T77 2394-2403 Chemical denotes oligomers http://purl.obolibrary.org/obo/CHEBI_132554
T78 2405-2408 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T79 2435-2444 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T80 2750-2753 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T81 2908-2922 Chemical denotes antiviral drug http://purl.obolibrary.org/obo/CHEBI_36044
T82 2908-2917 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T83 2918-2922 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T84 2976-2980 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T85 3018-3027 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T86 3067-3074 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T87 3204-3214 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T88 3343-3348 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T89 3442-3457 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T90 3442-3451 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T91 3452-3457 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T92 3573-3582 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T93 3583-3586 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T94 3619-3632 Chemical denotes cyclodextrins http://purl.obolibrary.org/obo/CHEBI_23456
T95 5106-5114 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T96 5316-5325 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T97 5441-5449 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T98 5484-5492 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T99 5566-5569 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T100 5585-5593 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T101 5607-5615 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T102 5645-5653 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T103 5684-5691 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T104 5781-5788 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T105 5860-5867 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T106 5956-5960 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T107 5962-5969 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T108 6221-6226 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T109 6247-6250 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T110 6334-6342 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T111 6383-6390 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T112 6476-6483 Chemical denotes polymer http://purl.obolibrary.org/obo/CHEBI_33839|http://purl.obolibrary.org/obo/CHEBI_60027
T114 6497-6504 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T115 6606-6613 Chemical denotes polymer http://purl.obolibrary.org/obo/CHEBI_33839|http://purl.obolibrary.org/obo/CHEBI_60027
T117 6638-6645 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T118 6690-6695 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T119 6700-6705 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T120 6712-6715 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T121 6795-6803 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T122 7092-7099 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T123 7220-7227 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T124 7287-7296 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T125 7532-7540 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T126 7559-7566 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T127 7724-7732 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T128 8187-8192 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T129 8193-8196 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T130 8566-8568 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T131 8606-8609 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T132 9168-9175 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T133 9940-9947 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T134 9996-9998 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T135 10079-10082 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T136 10447-10449 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T137 10854-10856 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T138 10926-10933 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T139 10969-10976 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T140 11422-11424 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T141 11630-11638 Chemical denotes aluminum http://purl.obolibrary.org/obo/CHEBI_28984
T142 11639-11643 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T144 11645-11649 Chemical denotes alum http://purl.obolibrary.org/obo/CHEBI_74768
T145 11895-11897 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T146 12024-12027 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T147 12190-12201 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T148 12283-12290 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T149 12353-12362 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T150 12427-12436 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T151 12475-12484 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T152 12751-12760 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T153 12794-12801 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T154 12909-12913 Chemical denotes alum http://purl.obolibrary.org/obo/CHEBI_74768
T155 13048-13056 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T156 13119-13124 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T157 13137-13145 Chemical denotes squalene http://purl.obolibrary.org/obo/CHEBI_15440
T158 13154-13168 Chemical denotes polysorbate 80 http://purl.obolibrary.org/obo/CHEBI_53426
T159 13154-13165 Chemical denotes polysorbate http://purl.obolibrary.org/obo/CHEBI_53422|http://purl.obolibrary.org/obo/CHEBI_53423|http://purl.obolibrary.org/obo/CHEBI_53424|http://purl.obolibrary.org/obo/CHEBI_53425
T163 13192-13203 Chemical denotes surfactants http://purl.obolibrary.org/obo/CHEBI_35195
T164 13351-13360 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T165 13514-13524 Chemical denotes tocopherol http://purl.obolibrary.org/obo/CHEBI_27013
T166 13564-13566 Chemical denotes AF http://purl.obolibrary.org/obo/CHEBI_73807
T167 13625-13633 Chemical denotes squalene http://purl.obolibrary.org/obo/CHEBI_15440
T168 13654-13669 Chemical denotes polyoxyethylene http://purl.obolibrary.org/obo/CHEBI_46793
T169 13683-13688 Chemical denotes ether http://purl.obolibrary.org/obo/CHEBI_25698
T170 13690-13698 Chemical denotes mannitol http://purl.obolibrary.org/obo/CHEBI_16899|http://purl.obolibrary.org/obo/CHEBI_29864
T172 13712-13718 Chemical denotes oleate http://purl.obolibrary.org/obo/CHEBI_30823
T173 13791-13799 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T174 13870-13877 Chemical denotes lipid A http://purl.obolibrary.org/obo/CHEBI_25051|http://purl.obolibrary.org/obo/CHEBI_47040|http://purl.obolibrary.org/obo/CHEBI_58712
T177 13870-13875 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T178 13907-13914 Chemical denotes agonist http://purl.obolibrary.org/obo/CHEBI_48705
T179 13920-13927 Chemical denotes saponin http://purl.obolibrary.org/obo/CHEBI_26605
T180 14095-14103 Chemical denotes aluminum http://purl.obolibrary.org/obo/CHEBI_28984
T181 14104-14113 Chemical denotes hydroxide http://purl.obolibrary.org/obo/CHEBI_16234
T182 14684-14692 Chemical denotes graphene http://purl.obolibrary.org/obo/CHEBI_36973
T183 14712-14728 Chemical denotes carbon nanotubes http://purl.obolibrary.org/obo/CHEBI_50594
T184 14712-14718 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T186 14736-14747 Chemical denotes polystyrene http://purl.obolibrary.org/obo/CHEBI_53276
T187 14872-14886 Chemical denotes graphene oxide http://purl.obolibrary.org/obo/CHEBI_132889
T188 14872-14880 Chemical denotes graphene http://purl.obolibrary.org/obo/CHEBI_36973
T189 14881-14886 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T191 14907-14919 Chemical denotes amino groups http://purl.obolibrary.org/obo/CHEBI_51142
T192 14907-14912 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T193 14962-14972 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T194 15083-15085 Chemical denotes M1 http://purl.obolibrary.org/obo/CHEBI_51079|http://purl.obolibrary.org/obo/CHEBI_139019|http://purl.obolibrary.org/obo/CHEBI_140152|http://purl.obolibrary.org/obo/CHEBI_34826
T198 15207-15216 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T199 15322-15332 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T200 15721-15729 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T201 16012-16020 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T202 16083-16091 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T203 16116-16123 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T204 16177-16189 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T205 16190-16202 Chemical denotes nanoparticle http://purl.obolibrary.org/obo/CHEBI_50803
T206 16231-16238 Chemical denotes saponin http://purl.obolibrary.org/obo/CHEBI_26605
T207 16358-16367 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T208 16526-16534 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T209 16754-16763 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T210 16822-16831 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T211 17065-17067 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T213 17098-17102 Chemical denotes alum http://purl.obolibrary.org/obo/CHEBI_74768
T214 17127-17135 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T215 17304-17308 Chemical denotes alum http://purl.obolibrary.org/obo/CHEBI_74768
T216 17601-17615 Chemical denotes antiviral drug http://purl.obolibrary.org/obo/CHEBI_36044
T217 17601-17610 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T218 17611-17615 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T219 18666-18668 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T221 18773-18778 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T222 18806-18808 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T224 18833-18835 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T226 18875-18877 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T228 19457-19474 Chemical denotes immunosuppressant http://purl.obolibrary.org/obo/CHEBI_35705
T229 19538-19542 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T230 19549-19553 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T231 19750-19767 Chemical denotes immunosuppressant http://purl.obolibrary.org/obo/CHEBI_35705
T232 19913-19917 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T233 20005-20029 Chemical denotes immunosuppressive agents http://purl.obolibrary.org/obo/CHEBI_35705
T234 20171-20178 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T235 20215-20217 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T237 21208-21222 Chemical denotes Octadecylamine http://purl.obolibrary.org/obo/CHEBI_63866
T238 21242-21255 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T239 22074-22079 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T240 22600-22606 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T242 22698-22700 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T244 22880-22886 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T246 22978-22986 Chemical denotes graphene http://purl.obolibrary.org/obo/CHEBI_36973
T247 23339-23343 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T248 23363-23372 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T249 23407-23410 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T251 23494-23497 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T253 23693-23716 Chemical denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523
T254 23702-23708 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T255 23718-23721 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T256 23742-23748 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T257 23925-23928 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T259 23986-23989 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T260 24017-24025 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T261 24027-24040 Chemical denotes nucleic acids http://purl.obolibrary.org/obo/CHEBI_33696
T262 24035-24040 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T263 24057-24063 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T264 24111-24114 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T266 24274-24277 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T268 24623-24626 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T269 24639-24645 Chemical denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708
T270 24646-24653 Chemical denotes yttrium http://purl.obolibrary.org/obo/CHEBI_33331
T271 24654-24662 Chemical denotes fluoride http://purl.obolibrary.org/obo/CHEBI_17051
T272 24684-24687 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T273 24700-24719 Chemical denotes zinc phthalocyanine http://purl.obolibrary.org/obo/CHEBI_51218
T274 24700-24704 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T276 24705-24719 Chemical denotes phthalocyanine http://purl.obolibrary.org/obo/CHEBI_34921
T277 24815-24818 Chemical denotes PEI http://purl.obolibrary.org/obo/CHEBI_144613|http://purl.obolibrary.org/obo/CHEBI_53231
T279 24895-24904 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T280 25091-25107 Chemical denotes transition metal http://purl.obolibrary.org/obo/CHEBI_27081
T281 25118-25126 Chemical denotes nitrides http://purl.obolibrary.org/obo/CHEBI_50882
T282 25249-25251 Chemical denotes Mn http://purl.obolibrary.org/obo/CHEBI_18291
T283 25279-25295 Chemical denotes transition metal http://purl.obolibrary.org/obo/CHEBI_27081
T284 25297-25299 Chemical denotes Ti http://purl.obolibrary.org/obo/CHEBI_33341
T285 25301-25303 Chemical denotes Zr http://purl.obolibrary.org/obo/CHEBI_33342
T286 25308-25310 Chemical denotes Mo http://purl.obolibrary.org/obo/CHEBI_28685
T287 25395-25397 Chemical denotes Cl http://purl.obolibrary.org/obo/CHEBI_23116
T288 25790-25792 Chemical denotes IR http://purl.obolibrary.org/obo/CHEBI_74061
T289 25804-25807 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T291 25860-25862 Chemical denotes IR http://purl.obolibrary.org/obo/CHEBI_74061
T292 25911-25914 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T294 25962-25970 Chemical denotes graphene http://purl.obolibrary.org/obo/CHEBI_36973
T295 26022-26025 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T297 26276-26284 Chemical denotes graphene http://purl.obolibrary.org/obo/CHEBI_36973
T298 26316-26326 Chemical denotes phosphorus http://purl.obolibrary.org/obo/CHEBI_28659|http://purl.obolibrary.org/obo/CHEBI_35895
T300 26338-26352 Chemical denotes carbon nitride http://purl.obolibrary.org/obo/CHEBI_29308
T301 26338-26344 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T303 26345-26352 Chemical denotes nitride http://purl.obolibrary.org/obo/CHEBI_29240|http://purl.obolibrary.org/obo/CHEBI_50882
T305 26354-26372 Chemical denotes tungsten disulfide http://purl.obolibrary.org/obo/CHEBI_30521
T306 26354-26362 Chemical denotes tungsten http://purl.obolibrary.org/obo/CHEBI_27998
T307 26363-26372 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T308 26378-26398 Chemical denotes molybdenum disulfide http://purl.obolibrary.org/obo/CHEBI_30704
T309 26378-26388 Chemical denotes molybdenum http://purl.obolibrary.org/obo/CHEBI_28685
T310 26389-26398 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T311 26446-26449 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T313 26540-26543 Chemical denotes PDT http://purl.obolibrary.org/obo/CHEBI_53228|http://purl.obolibrary.org/obo/CHEBI_60622
T315 27223-27225 Chemical denotes NP http://purl.obolibrary.org/obo/CHEBI_50803|http://purl.obolibrary.org/obo/CHEBI_53793|http://purl.obolibrary.org/obo/CHEBI_73425
T318 27396-27403 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T319 27418-27435 Chemical denotes organic compounds http://purl.obolibrary.org/obo/CHEBI_50860|http://purl.obolibrary.org/obo/CHEBI_72695
T321 27747-27750 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T322 27776-27783 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T323 27908-27916 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T324 28027-28030 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T325 28151-28154 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T326 28572-28578 Chemical denotes silver http://purl.obolibrary.org/obo/CHEBI_30512|http://purl.obolibrary.org/obo/CHEBI_9141
T328 28736-28740 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T329 29116-29119 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T330 29124-29128 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T331 29182-29190 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T332 31106-31110 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T333 31294-31298 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T334 31506-31514 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T335 31827-31830 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T336 31899-31902 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T337 32387-32393 Chemical denotes corona http://purl.obolibrary.org/obo/CHEBI_37409
T338 32550-32558 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T339 32628-32638 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T340 32628-32633 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T341 32634-32638 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T342 32671-32689 Chemical denotes glycosaminoglycans http://purl.obolibrary.org/obo/CHEBI_18085
T343 32691-32695 Chemical denotes GAGs http://purl.obolibrary.org/obo/CHEBI_18085
T344 32700-32715 Chemical denotes heparan sulfate http://purl.obolibrary.org/obo/CHEBI_28815
T345 32700-32707 Chemical denotes heparan http://purl.obolibrary.org/obo/CHEBI_24500
T346 32708-32715 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T347 32717-32719 Chemical denotes HS http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815
T349 32865-32873 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T350 32874-32884 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T351 32964-32967 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T352 33040-33044 Chemical denotes Gold http://purl.obolibrary.org/obo/CHEBI_29287
T353 33045-33048 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T354 33099-33109 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T355 33170-33185 Chemical denotes heparan sulfate http://purl.obolibrary.org/obo/CHEBI_28815
T356 33170-33177 Chemical denotes heparan http://purl.obolibrary.org/obo/CHEBI_24500
T357 33178-33185 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T358 33270-33272 Chemical denotes Au http://purl.obolibrary.org/obo/CHEBI_29287
T359 33273-33276 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T360 33539-33542 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T361 33591-33594 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T362 33656-33660 Chemical denotes gold http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050
T364 33661-33664 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T365 33680-33682 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T370 33805-33812 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T371 33830-33832 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T376 33938-33947 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T377 33948-33951 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T378 33953-33955 Chemical denotes Au http://purl.obolibrary.org/obo/CHEBI_29287
T379 33960-33970 Chemical denotes iron oxide http://purl.obolibrary.org/obo/CHEBI_50816|http://purl.obolibrary.org/obo/CHEBI_50820
T381 33960-33964 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T382 33965-33970 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T384 34018-34020 Chemical denotes HS http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815
T386 34262-34265 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T387 34292-34302 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T388 34357-34364 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T389 34650-34657 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T390 34787-34794 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T391 35009-35013 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T392 35014-35023 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T393 35086-35091 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T394 35401-35405 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T395 35555-35560 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T396 35867-35871 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T397 36356-36360 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T398 36514-36519 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T399 36561-36569 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T400 36676-36680 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T401 36681-36690 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T402 36713-36715 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T403 37004-37007 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T404 37235-37237 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T405 37301-37303 Chemical denotes Au http://purl.obolibrary.org/obo/CHEBI_29287
T406 37333-37342 Chemical denotes nanocages http://purl.obolibrary.org/obo/CHEBI_51117
T407 37344-37352 Chemical denotes nanorods http://purl.obolibrary.org/obo/CHEBI_50805
T408 37475-37478 Chemical denotes NPs http://purl.obolibrary.org/obo/CHEBI_50803
T409 37514-37519 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T410 37588-37592 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T411 37956-37958 Chemical denotes NP http://purl.obolibrary.org/obo/CHEBI_50803|http://purl.obolibrary.org/obo/CHEBI_53793|http://purl.obolibrary.org/obo/CHEBI_73425

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T19 4169-4175 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T20 7718-7723 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T21 14012-14021 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T22 14034-14043 Phenotype denotes papilloma http://purl.obolibrary.org/obo/HP_0012740
T23 18142-18156 Phenotype denotes Cytokine Storm http://purl.obolibrary.org/obo/HP_0033041
T24 18218-18232 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T25 18260-18285 Phenotype denotes cytokine release syndrome http://purl.obolibrary.org/obo/HP_0033041
T26 18470-18490 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T27 19205-19219 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T28 21503-21508 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T29 21763-21769 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T30 22386-22392 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T31 22812-22818 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T32 23541-23555 Phenotype denotes photosensitive http://purl.obolibrary.org/obo/HP_0000992
T33 24200-24209 Phenotype denotes papilloma http://purl.obolibrary.org/obo/HP_0012740
T34 24227-24243 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T35 26104-26114 Phenotype denotes stomatitis http://purl.obolibrary.org/obo/HP_0010280
T36 26467-26473 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T37 33431-33441 Phenotype denotes stomatitis http://purl.obolibrary.org/obo/HP_0010280
T38 37041-37046 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T39 37490-37495 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T20 299-305 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T21 299-305 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T22 2477-2488 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T23 5069-5084 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T24 5283-5298 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T25 5820-5826 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T26 5820-5826 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T27 6523-6538 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T28 6772-6781 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T29 7448-7463 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T30 14474-14489 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T31 14973-14982 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T32 15126-15141 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T33 15333-15342 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T34 16911-16924 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T35 16925-16934 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T36 17906-17922 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T37 18325-18340 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T38 18984-18999 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T39 19089-19104 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T40 19293-19308 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T41 20431-20452 http://purl.obolibrary.org/obo/GO_0070227 denotes lymphocytic apoptosis
T42 20443-20452 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T43 20443-20452 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T44 20605-20617 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T45 20642-20662 http://purl.obolibrary.org/obo/GO_0070227 denotes lymphocyte apoptosis
T46 20653-20662 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T47 20653-20662 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T48 20931-20939 http://purl.obolibrary.org/obo/GO_0015297 denotes exchange
T49 21324-21332 http://purl.obolibrary.org/obo/GO_0007610 denotes behavior
T50 21509-21517 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T51 21509-21517 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T52 21509-21517 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T53 21509-21517 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T54 22568-22585 http://purl.obolibrary.org/obo/GO_0008015 denotes blood circulation
T55 23778-23788 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T56 30522-30528 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T57 30547-30555 http://purl.obolibrary.org/obo/GO_0015297 denotes exchange
T58 32072-32078 http://purl.obolibrary.org/obo/GO_0098739 denotes Uptake
T59 32072-32078 http://purl.obolibrary.org/obo/GO_0098657 denotes Uptake
T60 34546-34552 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T61 34546-34552 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T62 34603-34618 http://purl.obolibrary.org/obo/GO_0051100 denotes inhibit binding
T63 34703-34726 http://purl.obolibrary.org/obo/GO_0019048 denotes virus–host interactions

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 2058-2073 GlycoEpitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T2 32700-32715 GlycoEpitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T3 32717-32719 GlycoEpitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086
T4 33170-33185 GlycoEpitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T5 34018-34020 GlycoEpitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T53 0-57 Sentence denotes Nanotechnology Tools to Inactivate SARS-CoV-2 in Patients
T54 58-255 Sentence denotes The main target of SARS-CoV-2 is the respiratory tract (upper airways, lung),36 although other organs might also be infected (e.g., gut, kidney) and vasculature21 also appears to be a prime target.
T55 256-329 Sentence denotes The expression of ACE2 probably determines uptake by different tissues.37
T56 330-588 Sentence denotes In addition to discussing immune-based approaches, because the lung is the most critically affected organ, we will center our discussion on the various options to inactivate the virus in the deep lung and to target the essential host cells for drug delivery.
T57 589-751 Sentence denotes The virus reaches the alveoli and enters alveolar epithelial type II cells (AECII), due to the relatively high abundance of ACE2 and a permissive cellular milieu.
T58 752-903 Sentence denotes These cells serve as a reservoir of the virus, which finally spreads throughout the lung, leading to the lung function impairment seen in severe cases.
T59 904-1126 Sentence denotes Airborne nanomaterials are optimally suited to penetrate into the deep lung due to the physicochemical properties of such aerosols, existing on the same size scale particles that penetrate most readily to the deep airways.
T60 1127-1286 Sentence denotes Hence, nanomedicine is already actively pursuing ideas to deliver drugs, therapeutic proteins, and mRNAs by exploiting nanodevices for pulmonary delivery.38,39
T61 1287-1447 Sentence denotes Moreover, the rapid emergence of SARS-CoV-2 has exposed one of the main weaknesses in the current medical landscape: the lack of broad-spectrum antiviral drugs.
T62 1448-1544 Sentence denotes At present, there are only a handful of approved antivirals, and they are mostly virus-specific.
T63 1545-1639 Sentence denotes Hence, when a new virus emerges, little can be done pharmacologically to slow down its spread.
T64 1640-1823 Sentence denotes Some research efforts have been focused on the development of broad-spectrum drugs, which could potentially offer some efficacy against future emerging viruses (and maybe SARS-CoV-2).
T65 1824-1997 Sentence denotes The various approaches developed over the years are mainly based on the creation of entry inhibitors.40,41 A highly conserved part in viruses is the attachment ligand (VAL).
T66 1998-2280 Sentence denotes In most known respiratory viruses,42 the VAL targets either heparan sulfate proteoglycans (HSPG)43 or sialic acids (SA).44 Both HSPG and SA mimics have shown in vitro ability to bind to viruses, blocking their interaction with cell membranes, and often in a broad-spectrum way.45−47
T67 2281-2668 Sentence denotes In the context of nanomedicine, many nanomaterials have been developed, ranging from polymers48 to dendrimers,49 oligomers, NPs,50 liposomes,51 and small molecules.52 However, successful clinical translation has been hindered by the fact that, upon dilution, these compounds lose efficacy as the virus-compound complex dissociates leaving viruses free to restart their replication cycle.
T68 2669-3407 Sentence denotes Recently, it has been shown that this limitation can be overcome by synthesizing NPs that, after binding, are able to inhibit viral infectivity irreversibly by permanently damaging the virion, refueling the hope for a true, broad-spectrum antiviral drug.53 Because the focus is also on the development of a drug specific to SARS-CoV-2, a good entry inhibitor could be based on blocking the S spike protein interaction with the cellular ACE2 receptor.19,21−23 Regardless of the specific approach, it is imperative that novel, effective antivirals be based on compounds that exhibit very low or negligible toxicity profiles, as patients will most likely need to receive those drugs for extended periods of time and will already be weakened.
T69 3408-3504 Sentence denotes For these reasons, when designing antiviral drugs, clearance mechanisms have to be kept in mind.
T70 3505-4027 Sentence denotes An example of this process is the recent redesign of broad-spectrum antiviral NPs into equally effective modified cyclodextrins.54 Moreover, nanotechnology may offer nanotheranostic approaches to fill the existing gap between diagnostics and therapy.55−57 The simultaneous management of both diagnostics and therapy for those suffering from COVID-19 or in future pandemics, as for many other diseases, is an additional potential strategy to take into consideration in which nanomaterials have proven to be effective tools.
T71 4028-4338 Sentence denotes The advantages of the capabilities of nanotechnology and nanomaterials for combined therapeutics and diagnostics has been widely explored in cancer research; however, there have been considerable efforts in the past few years to extend the scope of this approach to other areas including infectious diseases.58
T72 4340-4399 Sentence denotes Nanomaterial-Based Vaccine Development and Immunomodulation
T73 4400-4569 Sentence denotes Following the publication of the genetic sequence of SARS-CoV-2 on January 11, 2020, intense research efforts have been devoted to developing a vaccine against COVID-19.
T74 4570-4906 Sentence denotes With unprecedented speed, this extraordinary scientific mobilization led the first vaccine candidate to enter the Phase I human clinical trial on March 16, 2020, and other novel candidates are rapidly following.59 Up to May 22, 2020, there are 10 COVID-19 candidate vaccines in clinical evaluations and 114 in preclinical development.60
T75 4907-5115 Sentence denotes Concerning vaccine and immunization research, nanomaterials can assist in multiple ways to boost the upregulation required by the immune system and to direct the immune response specifically against antigens.
T76 5116-5356 Sentence denotes Immune-targeted nanotherapeutics can be developed through their rational manufacture at the nanoscale level by designing nanomaterials that are able to amplify host’s immune response, for instance as adjuvants in the context of vaccination.
T77 5357-5904 Sentence denotes The development of a vaccine will rely either on the direct administration of viral antigens (e.g., in the form of recombinant proteins, vectored vaccines, or whole inactivated or attenuated virus) or RNA- or DNA-encoding viral antigens.27 Candidate antigens for immunization are surface proteins such as the immunogenic spike protein (S1), which is already targeted by antibodies of convalescent patients.27 Because the S1 protein is also essential for cellular uptake, many researchers are using this protein as the primary target for a vaccine.
T78 5905-6067 Sentence denotes There are many issues related to the delivery of a drug, protein, or RNA into the patient as the cargo is often degraded, not bioavailable, or is swiftly cleared.
T79 6068-6194 Sentence denotes Nanotechnology provides multiple solutions to these challenges though, as nanocarriers can overcome some of these limitations.
T80 6195-7045 Sentence denotes Biocompatible polymeric-, lipid-based, or inorganic NPs can be tuned with respect to their physicochemical properties to encapsulate cargo proteins with high loading efficiency, improving protein delivery and pharmacokinetics over conventional approaches.38 Intranasal delivery of polymer-encapsulated antigen triggers a strong immune response, and the success of vaccination depends on the appropriate type of polymer in combination with the antigen.61,62 Similarly, researchers have developed lipid and lipid-based NPs as delivery platforms for mRNAs or siRNAs to enable the synthesis of key viral proteins for vaccination or to inactivate critical viral target genes, respectively.39 The field of therapeutic mRNAs to support vaccination has gained momentum, as well,63 at least in part due to nanotechnology-enabled strategies for cargo delivery.
T81 7046-7146 Sentence denotes Moreover, the versatility of nanoplatforms as antigen-presenting systems offers great opportunities.
T82 7147-7464 Sentence denotes Considering the possibility of random viral mutations that may alter the antigen shape, functionalizing nanomaterials with a wide number of molecules at the same time to target the virus, or motifs that are specific for pathogens, will increase the efficiency of vaccines and their ability to prevent viral infection.
T83 7465-7946 Sentence denotes Several companies are working on mRNA vaccines encoding SARS-CoV-2 proteins such as the spike protein, encapsulated in nanoliposomes with specific physicochemical properties that are potentially akin to those documented for immunization against certain tumor antigens.64 The design of such nanocarriers, which will need to escape recognition by scavenger cells and to be nontoxic and nonimmunogenic, is a challenge that will require substantial time prior to clinical availability.
T84 7947-8041 Sentence denotes On March 16, 2020, Moderna, through a partnership with the Vaccine Research Center at the U.S.
T85 8042-8603 Sentence denotes National Institutes of Health, enrolled the first participants into a Phase I clinical trial testing an mRNA vaccine (mRNA-1273) encapsulated in lipid NPs—a record time of just 63 days following sequence selection (NCT04283461).65 The enrollment of the first cohort of participants (18 to 55-year-old healthy subjects) concluded on April 16, 2020.66 CureVac and BioNTech (in partnership with Pfizer) are currently working on similar vaccines; Pfizer/BioNTech, in particular, have recently started the recruitment in Phase I/II trials (NCT04368728, NCT04380701).
T86 8604-8841 Sentence denotes A DNA plasmid vaccine by Inovio Pharmaceuticals (INO-4800) has showed promising results in mice and guinea pigs according to a recent article published in Nature Communications(67) and has entered Phase I testing in humans (NCT04336410).
T87 8842-9069 Sentence denotes Another candidate COVID-19 vaccine for Phase I clinical trial is from the University of Oxford and AstraZeneca (NCT04324606).68 Around 1110 people will take part in the trial, which started recruitment at the end of April 2020.
T88 9070-9176 Sentence denotes The vaccine is based on a chimpanzee adenovirus vaccine vector (ChAdOx1) and the SARS-CoV-2 spike protein.
T89 9177-9310 Sentence denotes Chimpanzee adenoviral vectors against different pathogens have been already tested in thousands of subjects with demonstrated safety.
T90 9311-9409 Sentence denotes To date, ChAdOx1 has been administered to six rhesus macaques exposed to high doses of SARS-CoV-2.
T91 9410-10045 Sentence denotes The vaccine was unable to prevent infections, although it reduced the severity of the disease: no signs of virus replication were observed in the lungs, with significantly lower levels of respiratory disease and no lung damage compared to control animals, according to a recent article deposited in bioRxiv.69 Another adenoviral vector vaccine developed by CanSino Biological Inc. and Beijing Institute of Biotechnology using a genetically engineered replication-defective adenovirus type 5 vector to express the SARS-CoV-2 spike protein (Ad5-nCoV) is currently being tested in Phase I/II trials (NCT04398147, NCT04341389, NCT0431312).
T92 10046-10234 Sentence denotes Although vaccines based on novel DNA and mRNA technologies might be promising, there are no such kinds of vaccines on the market, and it is unknown whether they can be effective in humans.
T93 10235-10467 Sentence denotes Moderna, for instance, has generated preliminary safety data on different mRNA-based vaccines targeting other respiratory viruses, but their more advanced program (on a cytomegalovirus vaccine) is still in Phase II clinical testing.
T94 10468-10864 Sentence denotes However, on May 18, Moderna announced that mRNA-1273 elicited antibody titers above the levels observed in convalescent individuals (and therefore considered potentially protective) in all eight initial participants across the 25 and 100 μg dose cohorts of the Phase I trial (NCT04283461).70 The company, after having received a fast-track approval from the FDA, is now moving on Phase II trials.
T95 10865-11621 Sentence denotes Conversely, strong evidence exists regarding the efficacy of protein-based vaccines such as recombinant-protein, viral-vector, attenuated, or inactivated vaccines across different infectious diseases, with licensed vaccines already existing for all of these platforms.27 All of the aforementioned approaches are currently being explored in the context of SARS-CoV-2.27 An inactivated vaccine developed by the China National Pharmaceutical Group (Sinopharm), in collaboration with the Wuhan Institute of Biological Products, is currently tested in a Phase I/II trial (ChiCTR2000031809), and a second inactivated vaccine (in collaboration with the Beijing Institute of Biological Products) has been currently approved for clinical testing (ChiCTR2000032459).
T96 11622-11932 Sentence denotes A third aluminum salt (alum) adjuvanted inactivated vaccine, developed by Beijing-based Sinovac Biotech’s, was able to provide partial or complete protection in rhesus macaques, according to a recent article published in Science,71 and is currently being tested in Phase I/II trials (NCT04383574, NCT04352608).
T97 11933-12156 Sentence denotes Live-attenuated vaccines are intrinsically immunogenic (e.g., due to the presence of viral DNA), but extensive safety tests are required due to the rare possibility of reversion to a pathogenic form able to cause infection.
T98 12157-12396 Sentence denotes Vaccine candidates based in this application have previously been designed for SARS-CoV with high stability.72,73 Recombinant-protein vaccines and inactivated vaccines are safer but might require adjuvants to increase their immunogenicity.
T99 12397-12467 Sentence denotes In the context of SARS-CoV-2, adjuvants are important for two reasons.
T100 12468-12742 Sentence denotes First, adjuvants might increase the efficacy of the vaccine, especially in subjects with impaired immunological function, such as the elderly, or in subjects with comorbidities resulting in immune dysfunctions; in these patient cohorts, SARS-CoV-2 has a high lethality rate.
T101 12743-12901 Sentence denotes Second, adjuvants can reduce the amount of vaccine protein(s) required per dose, which could facilitate scaling-up vaccine production in a reduced time frame.
T102 12902-14119 Sentence denotes Beyond alum, which is in fact a nanoscale material74 that was developed in the 1920s for the tetanus and diphtheria toxoids,75 approval for a new adjuvant did not occur until 1997, with the introduction of the oil-in-water emulsion of squalene oil and polysorbate 80 and sorbitan trioleate surfactants (MF59) in the seasonal influenza vaccine for the elderly.76 The use of MF59 was further expanded to pandemic and avian influenza vaccines.77 Other adjuvants in licensed vaccines have been approved since 2000, as well: (a) AS03 (used for pandemic and avian influenza vaccines), similar to MF59, but including α-tocopherol as an additional immune stimulant; (b) AF 03 (used for pandemic influenza vaccines), an alternative squalene emulsion containing polyoxyethylene, cetostearyl ether, mannitol, and orbitan oleate;78 (c) AS 01 (used for herpes zoster vaccine), a liposome-based vaccine adjuvant system containing two immunostimulants, 3-O-desacyl-4′-monophosphoryl lipid A (MPL, a Toll-like receptor 4 agonist) and saponin QS-21, which activates the ACT-NLRP3 inflammasome pathway;79 and (d) AS04 (used for hepatitis B and human papilloma virus vaccines), which is a combination of MPL and aluminum hydroxide.76,80
T103 14120-14490 Sentence denotes In this context, the concept of “nanoimmunity by design” relies on the rational design of distinct physicochemical properties and specific functionalization of nanomaterials intended for fine-tuning their potential effects on the immune system.81 Nanomaterials have emerged as promising tools for immune modulation, either stimulating or suppressing the immune response.
T104 14491-14628 Sentence denotes In fighting SARS-CoV-2, these properties may find applications for both prevention and therapy and in the context of vaccine development.
T105 14629-15526 Sentence denotes Mounting evidence indicates that nanomaterials such as graphene,82 nanodiamonds,83 carbon nanotubes,84 and polystyrene particles85 bear an intrinsic capacity to activate the immune system, depending on their functionalization.86 For instance, graphene oxide functionalized with amino groups (GO-NH2) induces activation of STAT1/IRF1 interferon signaling in monocytes and T cells, resulting in the production of T cell chemoattractants, and macrophage 1 (M1) 1/T-helper 1 (Th1) polarization of the immune response, with negligible toxicity.82 Remarkably, the ability of licensed adjuvants such as AS01 and AS03 to enhance adaptive immunity has been linked to their capacity to boost STAT1/IRF1 interferon signaling.87 In addition, recent SARS-CoV and MERS-CoV studies suggest that the development of a Th1-type response is central for controlling infection, which also may be true for SARS-CoV-2.88
T106 15527-16139 Sentence denotes Several groups and consortia have been screening and characterizing nanomaterials according to their immunomodulatory properties and absence of cytotoxicity.56,57,82−84,86 The development of an adjuvant for clinical use is a lengthy process that requires extensive Phase III randomized trials in large and diverse cohorts of subjects, and the process generally requires several years.76 Pharmaceutical giants such as GlaxoSmithKline (GSK), which owns the ASs mentioned above and other adjuvant platforms, are engaged in several partnerships to embed their adjuvant systems with SARS-CoV-2-protein-based vaccines.
T107 16140-16322 Sentence denotes A full-length recombinant SARS-CoV-2 glycoprotein nanoparticle vaccine adjuvanted with the saponin-based Matrix M developed by Novavax is in Phase I clinical testing (NCT04368988).89
T108 16323-16547 Sentence denotes Although it is unlikely that novel adjuvants would be used in the context of the current pandemic, the SARS-CoV-2 pandemic offers an opportunity to reflect on the potential of nanotechnology for vaccine adjuvant development.
T109 16548-16766 Sentence denotes In this context, it is critical to stream coherent pipelines covering in vitro and in vivo experiments specifically to select candidate materials that might be tested for clinical implementation as vaccine adjuvants.90
T110 16767-17247 Sentence denotes In this view, the status of nanomaterial-based vaccine adjuvants has been reviewed.91,92 In particular, immunomodulatory effects induced on the innate immune signaling have been demonstrated.91 For example, nanomaterials such as GO can elicit an inflammasome sensor (NLRP3)-dependent expression of IL-1β in macrophages.93 Notably, alum, the most commonly used adjuvant in human vaccines, induces the release of this cytokine in macrophages through the same NRLP-induced mechanism.
T111 17248-17350 Sentence denotes These results suggest that nanomaterials such as GO and alum may be useful for medical applications.94
T112 17351-17545 Sentence denotes Considering that new vaccine development typically requires years to be approved and applied to the general population, there is also an urgent need to study how to improve treatment approaches.
T113 17546-17781 Sentence denotes According to the first Phase III clinical studies, the antiviral drug Remdesivir, which was recently approved by the FDA for COVID-19 treatment in the United States, seems to be a promising treatment for adults diagnosed with COVID-19.
T114 17782-18101 Sentence denotes Nano-based strategies have already been applied to enhance the effectiveness of Remdesivir in the context of other emerging viral infections (Nipah virus),95 suggesting the suitability of nanotechnology to assist with similar strategies for the treatment of COVID-19 as well as other possible pandemics in the future.96
T115 18103-18157 Sentence denotes Can Nanotechnology Help to Control the Cytokine Storm?
T116 18158-18736 Sentence denotes One of the main features of COVID-19 is the triggering of a cytokine storm in the body, also known as cytokine release syndrome (CRS), which results from an excessive immune response and leads to the severe deterioration of patient health.25,97,98 This inflammatory storm is one of the major causes of the acute respiratory distress syndrome (ARDS) that is often associated with multiple-organ failure, representing the leading causes of death in critical patients.98 In particular, the role of interleukin (IL)-6 has been highlighted in patients requiring assisted ventilation.
T117 18737-18900 Sentence denotes Ongoing clinical trials are testing drugs that block the receptor of IL-6 (Tocilizumab, an anti-IL-6 receptor antibody, and Sarilumab) or IL-6 itself (Siltuximab).
T118 18901-19133 Sentence denotes Whereas a well-regulated cytokine response that is rapidly triggered by the host’s innate immunity can serve to prevent and to counteract an infection, an excessive, unbalanced, prolonged immune response can seriously harm the body.
T119 19134-19244 Sentence denotes Therefore, therapeutic strategies aimed at effectively suppressing the cytokine storm are under investigation.
T120 19245-19626 Sentence denotes Nanomaterials have been exploited to adjust the immune response to an optimized level, and such proprieties might be explored to inhibit cytokine releases.99 Nanosystems can enhance the specificity/efficiency of immunosuppressant delivery to target immune cells, with consequent reductions in drug dose, drug distribution to nontarget tissues and organs, and possible side effects.
T121 19627-19923 Sentence denotes In addition, specific nanotools can be designed to evade the immune system and to enhance the solubility of poorly soluble immunosuppressant agents; the potential of finely tuning their surface charge opens possibilities for encapsulation strategies and offers accommodation for a high drug load.
T122 19924-20030 Sentence denotes All of these mechanisms may also occur simultaneously, enhancing the activity of immunosuppressive agents.
T123 20031-20453 Sentence denotes Concerning the role of macrophages in COVID-19, the presence of ACE2-expressing CD68+CD169+ macrophages containing SARS-CoV-2 nucleoprotein antigen and showing an increased release of IL-6 was observed in infected spleen and lymph nodes.100 Notably, immunohistochemical and immunofluorescence analyses of lymph nodes and spleen tissue from autopsy samples of patients who died from COVID-19 revealed lymphocytic apoptosis.
T124 20454-20663 Sentence denotes The tissues infected by SARS-CoV-2 also showed an upregulated expression of Fas, suggesting a role for CD169+ macrophages in viral spreading, aberrant inflammation, and activation-induced lymphocyte apoptosis.
T125 20664-20940 Sentence denotes Moreover, histological examinations of biopsy samples of patients who died from COVID-19 revealed an increased alveolar exudate due to the extended neutrophil and monocyte infiltrate in lung capillaries with fibrin deposition, probably leading to difficulties in gas exchange.
T126 20941-21541 Sentence denotes Through nanomedicine, we envision therapeutic approaches aimed at targeting specific immune subpopulations to avoid these complications, and different nanomaterials have already been explored for their specific impact on different immune cell subpopulations.82,83,86 Octadecylamine-functionalized and dexamethasone-adsorbed nanodiamond promotes anti-inflammatory and proregenerative behavior in human macrophages in vitro.101 A low dose of this functionalized nanodiamond also reduced macrophage infiltration and expression of proinflammatory mediators iNOS and tumor necrosis factor (TNF)-α in mice.
T127 21542-21657 Sentence denotes Overall, these results suggest that nanodiamond particles may be useful as an inherently immunomodulatory platform.
T128 21658-22004 Sentence denotes Finally, the indiscriminate systemic suppression of the immune system may increase the susceptibility to sepsis due to underlying secondary bacterial infections that can exacerbate critical conditions in patients, causing death.102 Risk factors for mortality include acquired bacterial infections by opportunistic organisms and primary pathogens.
T129 22005-22225 Sentence denotes Using nanocarriers to achieve targeted delivery of immunosuppressive drugs, or the specific and controlled inhibition of only a specific immune cell subpopulation, can play a critical role in limiting such complications.
T130 22226-22393 Sentence denotes The fast and complete removal of pro-inflammatory cytokines from the bloodstream has been shown to increase survival significantly in patients with early stage sepsis.
T131 22394-22586 Sentence denotes Adsorption of cytokines from serum by extracorporeal perfusion through porous carbons is one of the most promising ways for their selective, quick, and complete removal from blood circulation.
T132 22587-23282 Sentence denotes Hierarchical carbon materials with tuned porosity have shown effective adsorption of many cytokines, including IL-6 and even the largest ones, such as TNF-α.103 Based on their demonstrated outstanding performance in removing sepsis-associated pro-inflammatory cytokines from blood, mesoporous carbon adsorbents with hierarchical structure, tuned pore size, and surface chemistry, as well as graphene with open and accessible surfaces104 have significant potential to quickly remove inflammatory cytokines associated with CRS and to prevent mortality arising from an uncontrolled inflammatory cascade, thereby providing enough time for the defense mechanisms of the human body to fight the virus.
T133 23284-23323 Sentence denotes Photodynamic Inactivation of SARS-CoV-2
T134 23324-23465 Sentence denotes In addition to drug- and vaccine-based antiviral strategies, photodynamic therapy (PDT) stands as a unique approach to inactivate SARS-CoV-2.
T135 23466-23789 Sentence denotes Using a light-based method, PDT attacks target cells via the excitation of photosensitive agents, called photosensitizers (PSs), with radiation characterized by a wavelength corresponding to its absorption spectrum to generate reactive oxygen species (ROS) in the presence of oxygen, which ultimately results in cell death.
T136 23790-24383 Sentence denotes Photodynamic therapy is primarily used for the clinical treatment of various oncological disorders.105 It was not until the 1970s that PDT was first used clinically against viruses,106 exploiting ROS production to damage virus proteins, nucleic acids, and—if present—lipids.107 Even though there are research efforts for PDT-based virotherapies against different viruses, including herpes simplex virus, human papilloma virus, and human immunodeficiency virus,106−109 clinical use of PDT is limited due to hydrophobicity of PSs, poor target specificity, and limited tissue penetration ability.
T137 24384-24752 Sentence denotes Most PSs are hydrophobic and aggregate in aqueous solutions, affecting their photochemical and photobiological properties.106,110 For this reason, Lim et al. have proposed a promising approach for photodynamic inactivation of viruses with NPs, developing sodium yttrium fluoride (NaYF4) upconversion NPs (UCNs) with zinc phthalocyanine PSs grafted onto their surfaces.
T138 24753-24876 Sentence denotes Unlike most PSs, these UCNs are coated with polyethylenimine (PEI), which render them hydrophilic and easier to manipulate.
T139 24877-25218 Sentence denotes These UCNs showed antiviral activity against Dengue virus serotype 2 and adenovirus type 5, which were used as models of enveloped and non-enveloped viruses, respectively.110 MXenes111,112 are a large family of 2D transition metal carbides, nitrides,113 and carbonitrides114 that exhibit unique electronic, optical, and catalytic properties.
T140 25219-25560 Sentence denotes They have the general formula Mn+1XnTx, where M is an early transition metal (Ti, Zr, V, Mo, etc.), X is C and/or N, Tx represents the surface functional groups (=O, −OH, −F, −Cl), and n = 1–4.115,116 Some examples include Ti3C2Tx, V2CTx, and Nb2CTx, with over 30 stoichiometric compositions already synthesized with more than 100 predicted.
T141 25561-25808 Sentence denotes Biocompatible MXenes, such as Ti3C2Tx, are hydrophilic and are among the most efficient light-to-heat transforming materials.117 The plasmon resonance extinction maxima of Ti3C2Tx is at 780 nm, enabling the use of near-infrared (IR) light for PDT.
T142 25809-25947 Sentence denotes Several other MXenes have absorption maxima in the IR range and have shown outstanding performance in PDT and theranostic applications.118
T143 25948-26619 Sentence denotes Fullerene and graphene are also good candidates for virus inactivation by PDT and have proved to be effective against Semliki Forest virus (SFV), vesicular stomatitis virus (VSV), HSV-1, HIV-1, mosquito iridovirus (MIV), and influenza A virus (IAV), as well as the phage MS2.107 In addition, several 2D nanomaterials, including graphene-based materials, MXenes, black phosphorus, graphitic carbon nitride, tungsten disulfide, and molybdenum disulfide, have been reported to improve the efficacy of PDT considerably for cancer treatment.56,57 Therefore, determining if such nanomaterial-based PDT protocols could be exploited to inactivate SARS-CoV-2 is of great interest.
T144 26621-26668 Sentence denotes Biomimetic Engineering of Nanodelivery Systems:
T145 26669-26701 Sentence denotes Artificial Viruses in the Making
T146 26702-26977 Sentence denotes In an effort to engineer the next generation of nanoscale vectors, scientists have moved from using inorganic components aimed at obtaining inert structures to utilizing biological building blocks that are able to convey additional functionalities to the resulting construct.
T147 26978-27216 Sentence denotes To cope with the complexity of the body and to evade the multiple layers of defense that tissues and organs have, it is critical to rely on the ability of certain materials to interact with, rather than to eschew, the biology of our body.
T148 27217-27459 Sentence denotes Every NP system conceived to date faces one common fate: whether injected, inhaled, ingested, or absorbed through our epithelia, all will at some point come into contact with the mixture of fluids and organic compounds that comprise the body.
T149 27460-27917 Sentence denotes Under such conditions, every material reacts in a unique way according to the conditions they individually face (i.e., the tissue or body region they are in), their composition (i.e., organic or inorganic), and their physical properties (i.e., size, shape, surface charge).119 Inorganic NPs can function as globular protein mimics because of their similar size, charge, shape, and surface features that can be chemically functionalized to resemble proteins.
T150 27918-28034 Sentence denotes These similarities can be used in biotechnology to control virus pathways or cell receptor interactions with NPs.120
T151 28035-28235 Sentence denotes Among the many attempts, the legendary accomplishments, and the epic failures, we could list thousands of different NPs, differing from one another thanks to the creative endeavors of their designers.
T152 28236-28497 Sentence denotes Despite their remarkable differences and researchers’ endeavors to make them one of a kind, they all aim to achieve one goal: to deliver in a specific way one particular form of payload, while remaining as unnoticed as possible by the body’s defense mechanisms.
T153 28498-28708 Sentence denotes For everyone who has made an effort to create their own version of such a silver bullet, it has come to mind that nature in its incredible variety had already invented a few ingenious solutions to this problem.
T154 28709-28851 Sentence denotes In the world of nano-based drug delivery, one entity dominates as the quintessential example of precision, efficiency, and stealth: the virus.
T155 28852-29039 Sentence denotes Not by chance, these two worlds share many features that span from the physical laws that govern their assembly and stability to the chemical similarities in their overall composition.121
T156 29040-29205 Sentence denotes Historically, the field of nanomedicine and the global endeavor to generate NPs for drug delivery arose from one of the greatest struggles in medicine: gene therapy.
T157 29206-29382 Sentence denotes At the core of that approach was the idea that viruses could be used as Trojan horses to deliver the correct sequence of the gene into the cells that harbored the mutated copy.
T158 29383-29564 Sentence denotes In order to identify the virus that offered the best delivery service, a cadre of viral strains and species were tested, adapted, and engineered to fit the aims and hit the targets.
T159 29565-30056 Sentence denotes It took decades of trial and error, of progressive adjustments, and a few tragic mistakes to identify the viruses that could provide the ideal backbone to develop viral vectors able to ferry genetic cargo into the target cell.122 In the midst of that global challenge, nanotechnology offered a safer and more controllable alternative: to generate bespoke structures that could replace viral vectors and do the same job, delivering a payload from the point of injection to the site of action.
T160 30057-30281 Sentence denotes Fast forward a few decades, and the promises made by both worlds seem to have finally become reality, with a number of active clinical trials, some clinical success stories, and a few commercial products in the market space.
T161 30282-30404 Sentence denotes Interestingly, the two worlds seem to have maintained a safe distance so as to avoid any collision or dangerous proximity.
T162 30405-30844 Sentence denotes Exchange of ideas between the fields of gene therapy and nanomedicine is limited, and the potential for disciplinary growth through knowledge exchange has remained elusive to scientists in both fields.5 Many scientists have suggested that nanotechnologists could find inspiration in the mechanisms devised by viruses to elude immune surveillance, to overcome biological barriers, and to deliver their genetic payload with high specificity.
T163 30845-31016 Sentence denotes Similarly, gene therapists would find high-tech solutions to their scalability and safety issues in looking at the new generations of biomimetic particles being generated.
T164 31017-31290 Sentence denotes The principles of biomimicry and bioinspiration have been used to design and to engineer drug-delivery technologies that reproduce or recapitulate biological materials, for what pertains to not only their structure and chemistry but also, more importantly, their functions.
T165 31291-31831 Sentence denotes In drug delivery, surface recognition and nanoscale interactions between materials and biological entities are key to the success of the delivery strategy, and the use of biological building blocks such as membrane proteins has been proposed as a way to convey targeting and shielding moieties simultaneously.123 One can only hope that the recent events and global attention that viruses are capturing in the scientific world will spur a renewed interest in finding ways to adapt viral features and mechanisms of action to the world of NPs.
T166 31832-32043 Sentence denotes Increased focus in this field would be useful to create virus-like NPs able to circulate in the blood system, overcoming the endothelial barrier, and to deliver their therapeutic payload with high efficiency.124
T167 32045-32150 Sentence denotes Interference with Cellular Uptake, Immobilization, and Inactivation of the Virus Outside of the Host Cell
T168 32151-32258 Sentence denotes Nanomaterials can be synthesized with a high specific surface area of a few hundred square meters per gram.
T169 32259-32394 Sentence denotes Therefore, dependent on the surface properties, nanomaterials efficiently adsorb biomolecules and form a so-called biomolecular corona.
T170 32395-32535 Sentence denotes This passive, nontargeted adsorption might be utilized to bind viruses, provided that the selected nanomaterial is relatively biocompatible.
T171 32536-33039 Sentence denotes Viral surface proteins are often modified by sugar moieties or encompass positively charged amino acid patches that bind to lectins or glycosaminoglycans (GAGs) of heparan sulfate (HS), respectively.32 Robust interactions of virus particles with these host receptors is ensured by multivalent binding, which is likely why single-molecule inhibitors often are not capable of efficiently perturbing this key event but multivalent NPs are superior to block binding of different viruses to the host cell.125
T172 33040-33234 Sentence denotes Gold NPs capped with mercaptoethanesulfonate are effective inhibitors of HSV type 1 infection as they mimic cell-surface-receptor heparan sulfate and, therefore, competitively bind to the virus.
T173 33235-33340 Sentence denotes Interestingly, polyvalent sulfated Au NPs inhibit virus binding to the host cell dependent on their size.
T174 33341-33518 Sentence denotes Nanoparticles of diameters equal to and larger than the virus diameter (in this case, the stomatitis virus) more efficiently inhibit the binding to cells than smaller particles.
T175 33519-33756 Sentence denotes Most likely, larger NPs efficiently cross-link virions, whereas smaller NPs simply decorate the viral surface.126 Papp et al. found that gold NPs decorated with SA effectively inhibited the binding of influenza virus to the target cells.
T176 33757-34303 Sentence denotes In this case, viral recognition via its surface protein hemagglutinin of SA on the host cell membrane was a prerequisite for cellular entry.127 More recently, Cagno et al. reported antiviral NPs (Au and iron oxide core) with long and flexible linkers mimicking HS that strongly bind and inactivate viruses such as respiratory syncytial virus in vitro and in vivo in a lung infection model and even led to irreversible viral deformation.53 Hence, there is ample evidence that biocompatible, functionalized NPs can act as broad-spectrum antivirals.
T177 34304-34494 Sentence denotes Notably, the receptor-binding domain of the spike S1 protein of SARS-CoV-2 binds not only to ACE2 but also to heparin128 and, thus, might be targeted by similar approaches as outlined above.
T178 34495-34903 Sentence denotes One of the most recent strategies to inhibit viral uptake is based on administration of recombinant ACE2 to inhibit binding competitively via the spike S1 protein.21 Knowing that multivalency is key to block virus–host interactions reliably, researchers have speculated that a nanostructured carrier could not only improve delivery and cargo stability but also might dramatically enhance binding strength.129
T179 34905-34985 Sentence denotes Speeding up the Nanomedicine-Based Approaches for COVID-19 by In Silico Analysis
T180 34986-35620 Sentence denotes Currently, repurposing drug molecules is a key strategy for identifying approved or investigational drugs outside the scope of the original medical indication that can be used to fight COVID-19.130,131 There are various advantages to this strategy, including already-established safety profiles, fast transition to clinical studies, and less investment needed, compared to the process of developing an entirely new drug.132,133 Therefore, these advantages have the potential to result in less risky and more rapid returns on investment in the development of repurposed drugs, benefits that are particularly important during pandemics.
T181 35621-35754 Sentence denotes In addition to rapid diagnosis, making recommendations to physicians about rapid treatment methods can save the lives of many people.
T182 35755-36014 Sentence denotes Combining in silico tools such as molecular docking, molecular dynamics, and computational chemistry with large drug databases provides a great advantage in selecting “possible candidates” from among thousands of pharmaceutically active substances (Figure 3).
T183 36015-36177 Sentence denotes In silico analyses should be supported by the literature, expert opinions (pharmacologists and clinicians), and, when possible, preclinical and clinical findings.
T184 36178-36337 Sentence denotes After selecting the best candidates following in silico analyses, detailed in vitro and in vivo experimentation should be undertaken prior to clinical studies.
T185 36338-36597 Sentence denotes Recently, various drug-repurposing studies have been published to assist in the global COVID-19 pandemic response.134−136 Such studies aim to identify whether already-approved drugs have the capacity to interact with viral proteins or receptors on host cells.
T186 36598-36712 Sentence denotes Figure 3 Schematic of how in silico analysis can be used to select candidate drug molecules for clinical studies.
T187 36713-36736 Sentence denotes MD, molecular dynamics.
T188 36737-36969 Sentence denotes In nanomedicine, computational models have recently garnered attention; such work may help to identify how nanomaterials interact with biological systems and to determine how the efficacy of these nanotherapeutics could be improved.
T189 36970-37798 Sentence denotes Computational models indicate how NPs are taken up by healthy cells or tumor cells, enabling better predictions regarding the pharmacokinetic and pharmacodynamic properties of these materials.134 For example, Lunnoo et al. used a coarse-grained molecular dynamics (MD) simulation to observe the internalization pathways of various Au nanostructures (nanospheres, nanocages, nanorods, nanoplates, and nanohexapods) into an idealized mammalian plasma membrane.137 Other studies have simulated how different NPs can target tumor cells and deliver drugs.138,139 Therefore, in silico approaches that are currently used for drug repurposing, including molecular docking, molecular dynamics, and computational chemistry, constitute valuable tools to aid preclinical and clinical studies of nanomaterials directed for disease treatment.
T190 37799-38001 Sentence denotes Considering the urgent need for nanomedicine against the current pandemic, in silico analyses may be especially useful in guiding the rational design of new NP formulations required to fight SARS-CoV-2.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
195 35-45 Species denotes SARS-CoV-2 Tax:2697049
200 274-278 Gene denotes ACE2 Gene:59272
201 77-87 Species denotes SARS-CoV-2 Tax:2697049
202 95-106 Species denotes respiratory Tax:12814
203 174-182 Disease denotes infected MESH:D007239
205 713-717 Gene denotes ACE2 Gene:59272
217 2126-2130 Gene denotes HSPG Gene:6383
218 2089-2093 Gene denotes HSPG Gene:6383
219 1320-1330 Species denotes SARS-CoV-2 Tax:2697049
220 1811-1821 Species denotes SARS-CoV-2 Tax:2697049
221 2012-2023 Species denotes respiratory Tax:12814
222 1992-1995 Chemical denotes VAL
223 2039-2042 Chemical denotes VAL
224 2058-2073 Chemical denotes heparan sulfate MESH:D006497
225 2100-2112 Chemical denotes sialic acids MESH:D012794
226 2114-2116 Chemical denotes SA MESH:D012794
227 2135-2137 Chemical denotes SA MESH:D012794
238 3105-3109 Gene denotes ACE2 Gene:59272
239 3059-3060 Gene denotes S Gene:43740568
240 3061-3066 Gene denotes spike Gene:43740568
241 2993-3003 Species denotes SARS-CoV-2 Tax:2697049
242 3295-3303 Species denotes patients Tax:9606
243 3619-3632 Chemical denotes cyclodextrins MESH:D003505
244 3273-3281 Disease denotes toxicity MESH:D064420
245 3846-3854 Disease denotes COVID-19 MESH:C000657245
246 4169-4175 Disease denotes cancer MESH:D009369
247 4316-4335 Disease denotes infectious diseases MESH:D003141
252 4453-4463 Species denotes SARS-CoV-2 Tax:2697049
253 4692-4697 Species denotes human Tax:9606
254 4560-4568 Disease denotes COVID-19 MESH:C000657245
255 4817-4825 Disease denotes COVID-19 MESH:C000657245
258 5678-5683 Gene denotes spike Gene:43740568
259 5754-5762 Species denotes patients Tax:9606
261 5987-5994 Species denotes patient Tax:9606
266 6221-6226 Chemical denotes lipid MESH:D008055
267 6690-6695 Chemical denotes lipid MESH:D008055
268 6700-6705 Chemical denotes lipid MESH:D008055
269 7448-7463 Disease denotes viral infection MESH:D001102
273 7553-7558 Gene denotes spike Gene:43740568
274 7521-7531 Species denotes SARS-CoV-2 Tax:2697049
275 7718-7723 Disease denotes tumor MESH:D009369
284 8558-8568 Gene denotes Phase I/II
285 8039-8040 Gene denotes S Gene:43740568
286 8092-8104 Species denotes participants Tax:9606
287 8311-8323 Species denotes participants Tax:9606
288 8695-8699 Species denotes mice Tax:10090
289 8704-8715 Species denotes guinea pigs Tax:10141
290 8820-8826 Species denotes humans Tax:9606
291 8187-8192 Chemical denotes lipid MESH:D008055
308 9949-9952 Gene denotes Ad5 Gene:8081
309 9934-9939 Gene denotes spike Gene:43740568
310 9162-9167 Gene denotes spike Gene:43740568
311 9988-9998 Gene denotes Phase I/II
312 8982-8988 Species denotes people Tax:9606
313 9096-9117 Species denotes chimpanzee adenovirus Tax:310542
314 9151-9161 Species denotes SARS-CoV-2 Tax:2697049
315 9177-9187 Species denotes Chimpanzee Tax:9598
316 9357-9372 Species denotes rhesus macaques Tax:9544
317 9398-9408 Species denotes SARS-CoV-2 Tax:2697049
318 9883-9900 Species denotes adenovirus type 5 Tax:28285
319 9923-9933 Species denotes SARS-CoV-2 Tax:2697049
320 9953-9957 Species denotes nCoV Tax:2697049
321 8860-8868 Disease denotes COVID-19 MESH:C000657245
322 9444-9454 Disease denotes infections MESH:D007239
323 9598-9617 Disease denotes respiratory disease MESH:D012140
327 10227-10233 Species denotes humans Tax:9606
328 10671-10683 Species denotes participants Tax:9606
329 10345-10356 Species denotes respiratory Tax:12814
336 11414-11424 Gene denotes Phase I/II
337 11220-11230 Species denotes SARS-CoV-2 Tax:2697049
338 11783-11798 Species denotes rhesus macaques Tax:9544
339 11630-11643 Chemical denotes aluminum salt
340 11645-11649 Chemical denotes alum
341 11045-11064 Disease denotes infectious diseases MESH:D003141
347 12236-12244 Species denotes SARS-CoV Tax:694009
348 12415-12425 Species denotes SARS-CoV-2 Tax:2697049
349 12688-12695 Species denotes patient Tax:9606
350 12705-12715 Species denotes SARS-CoV-2 Tax:2697049
351 12146-12155 Disease denotes infection MESH:D007239
366 13886-13906 Gene denotes Toll-like receptor 4 Gene:7099
367 13959-13964 Gene denotes NLRP3 Gene:114548
368 14028-14049 Species denotes human papilloma virus Tax:10566
369 13227-13236 Species denotes influenza Tax:11320
370 13323-13332 Species denotes influenza Tax:11320
371 13460-13469 Species denotes influenza Tax:11320
372 13589-13598 Species denotes influenza Tax:11320
373 13112-13115 Chemical denotes oil MESH:D009821
374 13119-13124 Chemical denotes water MESH:D014867
375 13137-13149 Chemical denotes squalene oil MESH:D013185
376 13154-13168 Chemical denotes polysorbate 80 MESH:D011136
377 12995-13002 Disease denotes tetanus MESH:D013746
378 13564-13566 Disease denotes AF MESH:D001281
379 14012-14023 Disease denotes hepatitis B MESH:D006509
381 14503-14513 Species denotes SARS-CoV-2 Tax:2697049
395 14951-14956 Gene denotes STAT1 Gene:6772
396 14957-14961 Gene denotes IRF1 Gene:3659
397 15311-15316 Gene denotes STAT1 Gene:6772
398 15317-15321 Gene denotes IRF1 Gene:3659
399 15366-15374 Species denotes SARS-CoV Tax:694009
400 15379-15387 Species denotes MERS-CoV Tax:1335626
401 15513-15523 Species denotes SARS-CoV-2 Tax:2697049
402 14684-14692 Chemical denotes graphene MESH:D006108
403 14712-14718 Chemical denotes carbon MESH:D002244
404 14736-14747 Chemical denotes polystyrene MESH:D011137
405 14872-14886 Chemical denotes graphene oxide MESH:C000628730
406 15159-15167 Disease denotes toxicity MESH:D064420
407 15475-15484 Disease denotes infection MESH:D007239
413 15944-15959 Gene denotes GlaxoSmithKline
414 16105-16115 Species denotes SARS-CoV-2 Tax:2697049
415 16166-16176 Species denotes SARS-CoV-2 Tax:2697049
416 16231-16238 Chemical denotes saponin MESH:D012503
417 15660-15683 Disease denotes absence of cytotoxicity MESH:D064420
419 16426-16436 Species denotes SARS-CoV-2 Tax:2697049
427 17034-17039 Gene denotes NLRP3 Gene:114548
428 17065-17070 Gene denotes IL-1β Gene:3552
429 17139-17144 Species denotes human Tax:9606
430 16996-16998 Chemical denotes GO MESH:C000628730
431 17098-17102 Chemical denotes alum
432 17297-17299 Chemical denotes GO MESH:C000628730
433 17304-17308 Chemical denotes alum
441 17924-17935 Species denotes Nipah virus Tax:121791
442 17616-17626 Chemical denotes Remdesivir MESH:C000606551
443 17862-17872 Chemical denotes Remdesivir MESH:C000606551
444 17671-17679 Disease denotes COVID-19 MESH:C000657245
445 17772-17780 Disease denotes COVID-19 MESH:C000657245
446 17906-17922 Disease denotes viral infections MESH:D001102
447 18040-18048 Disease denotes COVID-19 MESH:C000657245
464 18653-18671 Gene denotes interleukin (IL)-6 Gene:3569
465 18806-18810 Gene denotes IL-6 Gene:3569
466 18833-18837 Gene denotes IL-6 Gene:3569
467 18875-18879 Gene denotes IL-6 Gene:3569
468 18382-18389 Species denotes patient Tax:9606
469 18614-18622 Species denotes patients Tax:9606
470 18696-18704 Species denotes patients Tax:9606
471 18812-18823 Chemical denotes Tocilizumab MESH:C502936
472 18861-18870 Chemical denotes Sarilumab MESH:C000592401
473 18888-18898 Chemical denotes Siltuximab MESH:C504234
474 18186-18194 Disease denotes COVID-19 MESH:C000657245
475 18287-18290 Disease denotes CRS MESH:D003398
476 18464-18499 Disease denotes acute respiratory distress syndrome MESH:D012128
477 18501-18505 Disease denotes ARDS MESH:D012128
478 18537-18559 Disease denotes multiple-organ failure MESH:D009102
479 18596-18601 Disease denotes death MESH:D003643
481 19042-19051 Disease denotes infection MESH:D007239
505 20095-20099 Gene denotes ACE2 Gene:59272
506 20111-20115 Gene denotes CD68 Gene:968
507 20116-20121 Gene denotes CD169 Gene:6614
508 20215-20219 Gene denotes IL-6 Gene:3569
509 20557-20562 Gene denotes CD169 Gene:6614
510 21494-21498 Gene denotes iNOS Gene:18126
511 21503-21532 Gene denotes tumor necrosis factor (TNF)-α Gene:21926
512 20390-20398 Species denotes patients Tax:9606
513 20478-20488 Species denotes SARS-CoV-2 Tax:2697049
514 20721-20729 Species denotes patients Tax:9606
515 21336-21341 Species denotes human Tax:9606
516 21536-21540 Species denotes mice Tax:10090
517 20146-20156 Species denotes SARS-CoV-2 Tax:2697049
518 21208-21222 Chemical denotes Octadecylamine MESH:C009317
519 21242-21255 Chemical denotes dexamethasone MESH:D003907
520 20069-20077 Disease denotes COVID-19 MESH:C000657245
521 20236-20244 Disease denotes infected MESH:D007239
522 20403-20407 Disease denotes died MESH:D003643
523 20413-20421 Disease denotes COVID-19 MESH:C000657245
524 20466-20474 Disease denotes infected MESH:D007239
525 20605-20617 Disease denotes inflammation MESH:D007249
526 20734-20738 Disease denotes died MESH:D003643
527 20744-20752 Disease denotes COVID-19 MESH:C000657245
535 21862-21870 Species denotes patients Tax:9606
536 21671-21685 Chemical denotes indiscriminate
537 21763-21769 Disease denotes sepsis MESH:D018805
538 21808-21818 Disease denotes infections MESH:D007239
539 21880-21885 Disease denotes death MESH:D003643
540 21907-21916 Disease denotes mortality MESH:D003643
541 21934-21954 Disease denotes bacterial infections MESH:D001424
554 22698-22702 Gene denotes IL-6 Gene:3569
555 22738-22743 Gene denotes TNF-α Gene:7124
556 22360-22368 Species denotes patients Tax:9606
557 23252-23257 Species denotes human Tax:9606
558 22472-22479 Chemical denotes carbons MESH:D002244
559 22600-22606 Chemical denotes carbon MESH:D002244
560 22869-22886 Chemical denotes mesoporous carbon
561 22978-22986 Chemical denotes graphene MESH:D006108
562 22386-22392 Disease denotes sepsis MESH:D018805
563 22812-22818 Disease denotes sepsis MESH:D018805
564 23108-23111 Disease denotes CRS MESH:D003398
565 23127-23136 Disease denotes mortality MESH:D003643
575 23454-23464 Species denotes SARS-CoV-2 Tax:2697049
576 24194-24215 Species denotes human papilloma virus Tax:10566
577 24221-24249 Species denotes human immunodeficiency virus Tax:12721
578 23693-23716 Chemical denotes reactive oxygen species MESH:D017382
579 23718-23721 Chemical denotes ROS MESH:D017382
580 23742-23748 Chemical denotes oxygen MESH:D010100
581 23986-23989 Chemical denotes ROS MESH:D017382
582 24057-24063 Chemical denotes lipids MESH:D008055
583 23783-23788 Disease denotes death MESH:D003643
598 24531-24534 Gene denotes Lim Gene:10611
599 24922-24934 Species denotes Dengue virus Tax:12637
600 24950-24967 Species denotes adenovirus type 5 Tax:28285
601 24639-24662 Chemical denotes sodium yttrium fluoride
602 24664-24669 Chemical denotes NaYF4
603 24700-24719 Chemical denotes zinc phthalocyanine MESH:C052159
604 24797-24813 Chemical denotes polyethylenimine MESH:D011094
605 24815-24818 Chemical denotes PEI MESH:D011094
606 25052-25058 Chemical denotes MXenes
607 25088-25116 Chemical denotes 2D transition metal carbides
608 25118-25126 Chemical denotes nitrides
609 25135-25148 Chemical denotes carbonitrides
610 25290-25295 Chemical denotes metal MESH:D008670
611 25391-25392 Chemical denotes F MESH:D005461
630 26066-26086 Species denotes Semliki Forest virus Tax:11033
631 26094-26120 Species denotes vesicular stomatitis virus Tax:11276
632 26128-26133 Species denotes HSV-1 Tax:10298
633 26135-26140 Species denotes HIV-1 Tax:11676
634 26173-26190 Species denotes influenza A virus Tax:11320
635 26213-26222 Species denotes phage MS2 Tax:12022
636 26587-26597 Species denotes SARS-CoV-2 Tax:2697049
637 26088-26091 Species denotes SFV Tax:11033
638 26122-26125 Species denotes VSV Tax:11276
639 26192-26195 Species denotes IAV Tax:11320
640 25948-25957 Chemical denotes Fullerene MESH:D037741
641 25962-25970 Chemical denotes graphene MESH:D006108
642 26276-26284 Chemical denotes graphene MESH:D006108
643 26302-26308 Chemical denotes MXenes
644 26310-26326 Chemical denotes black phosphorus MESH:D010758
645 26354-26372 Chemical denotes tungsten disulfide
646 26378-26398 Chemical denotes molybdenum disulfide MESH:C082964
647 26467-26473 Disease denotes cancer MESH:D009369
649 29285-29291 Species denotes horses Tax:9796
654 32581-32586 Chemical denotes sugar MESH:D000073893
655 32671-32689 Chemical denotes glycosaminoglycans MESH:D006025
656 32700-32715 Chemical denotes heparan sulfate MESH:D006497
657 32717-32719 Chemical denotes HS MESH:D006497
673 33148-33169 Gene denotes cell-surface-receptor Gene:57126
674 34397-34401 Gene denotes ACE2 Gene:59272
675 33720-33735 Species denotes influenza virus Tax:11309
676 34071-34098 Species denotes respiratory syncytial virus Tax:12814
677 34368-34378 Species denotes SARS-CoV-2 Tax:2697049
678 33061-33084 Chemical denotes mercaptoethanesulfonate MESH:D015080
679 33170-33185 Chemical denotes heparan sulfate MESH:D006497
680 33680-33682 Chemical denotes SA MESH:D012794
681 33830-33832 Chemical denotes SA MESH:D012794
682 33960-33970 Chemical denotes iron oxide MESH:C000499
683 34414-34421 Chemical denotes heparin MESH:D006493
684 33113-33133 Disease denotes HSV type 1 infection MESH:C536395
685 33431-33447 Disease denotes stomatitis virus MESH:D013280
686 34125-34139 Disease denotes lung infection MESH:D012141
687 34175-34192 Disease denotes viral deformation
689 34595-34599 Gene denotes ACE2 Gene:59272
691 34955-34963 Disease denotes COVID-19 MESH:C000657245
695 35747-35753 Species denotes people Tax:9606
696 35171-35179 Disease denotes COVID-19 MESH:C000657245
697 36425-36433 Disease denotes COVID-19 MESH:C000657245
703 37402-37411 Species denotes mammalian Tax:9606
704 37990-38000 Species denotes SARS-CoV-2 Tax:2697049
705 37301-37303 Chemical denotes Au MESH:D006046
706 37041-37046 Disease denotes tumor MESH:D009369
707 37490-37495 Disease denotes tumor MESH:D009369

2_test

Id Subject Object Predicate Lexical cue
32519842-32246845-158468 135-137 32246845 denotes 36
32519842-32333836-158469 218-220 32333836 denotes 21
32519842-32413319-158470 327-329 32413319 denotes 37
32519842-25263223-158471 2118-2120 25263223 denotes 44
32519842-21384484-158472 2275-2277 21384484 denotes 45
32519842-19447134-158473 2278-2280 19447134 denotes 47
32519842-29894156-158474 2391-2393 29894156 denotes 49
32519842-29472127-158475 2422-2424 29472127 denotes 51
32519842-30846569-158476 2445-2447 30846569 denotes 52
32519842-29251725-158477 2923-2925 29251725 denotes 53
32519842-32015507-158478 3119-3121 32015507 denotes 19
32519842-32333836-158479 3122-3124 32333836 denotes 21
32519842-32142651-158480 3125-3127 32142651 denotes 23
32519842-32064341-158481 3633-3635 32064341 denotes 54
32519842-32031781-158482 3755-3757 32031781 denotes 55
32519842-32373222-158483 3758-3760 32373222 denotes 57
32519842-30599229-158484 4336-4338 30599229 denotes 58
32519842-32259480-158485 5594-5596 32259480 denotes 27
32519842-32259480-158486 5763-5765 32259480 denotes 27
32519842-20562880-158487 6646-6648 20562880 denotes 61
32519842-22073184-158488 6649-6651 22073184 denotes 62
32519842-26040878-158489 6965-6967 26040878 denotes 63
32519842-27281205-158490 7733-7735 27281205 denotes 64
32519842-32433465-158491 8781-8783 32433465 denotes 67
32519842-32259480-158492 11133-11135 32259480 denotes 27
32519842-32259480-158493 11231-11233 32259480 denotes 27
32519842-32376603-158494 11851-11853 32376603 denotes 71
32519842-26513244-158495 12265-12267 26513244 denotes 72
32519842-25609816-158496 12268-12270 25609816 denotes 73
32519842-30323958-158497 12952-12954 30323958 denotes 74
32519842-28734174-158498 13026-13028 28734174 denotes 75
32519842-29801750-158499 13261-13263 29801750 denotes 76
32519842-22941944-158500 13719-13721 22941944 denotes 78
32519842-27448771-158501 13986-13988 27448771 denotes 79
32519842-29801750-158502 14114-14116 29801750 denotes 76
32519842-21815697-158503 14117-14119 21815697 denotes 80
32519842-29061960-158504 14693-14695 29061960 denotes 82
32519842-23507086-158505 14729-14731 23507086 denotes 84
32519842-26854393-158506 14757-14759 26854393 denotes 85
32519842-24885781-158507 14855-14857 24885781 denotes 86
32519842-29061960-158508 15168-15170 29061960 denotes 82
32519842-28855902-158509 15343-15345 28855902 denotes 87
32519842-32105090-158510 15524-15526 32105090 denotes 88
32519842-32373222-158511 15687-15689 32373222 denotes 57
32519842-29061960-158512 15690-15692 29061960 denotes 82
32519842-23507086-158513 15693-15695 23507086 denotes 84
32519842-24885781-158514 15696-15698 24885781 denotes 86
32519842-29801750-158515 15911-15913 29801750 denotes 76
32519842-26791076-158516 16764-16766 26791076 denotes 90
32519842-30774955-158517 16853-16855 30774955 denotes 92
32519842-26389709-158518 17086-17088 26389709 denotes 93
32519842-30387986-158519 17348-17350 30387986 denotes 94
32519842-30904587-158520 17937-17939 30904587 denotes 95
32519842-32325025-158521 18397-18399 32325025 denotes 25
32519842-32192578-158522 18400-18402 32192578 denotes 97
32519842-29061960-158523 21199-21201 29061960 denotes 82
32519842-24885781-158524 21205-21207 24885781 denotes 86
32519842-31198584-158525 21363-21366 31198584 denotes 101
32519842-32171076-158526 21886-21889 32171076 denotes 102
32519842-21617154-158527 23889-23892 21617154 denotes 105
32519842-12791463-158528 23971-23974 12791463 denotes 106
32519842-31397467-158529 24064-24067 31397467 denotes 107
32519842-12791463-158530 24250-24253 12791463 denotes 106
32519842-22852040-158531 24254-24257 22852040 denotes 109
32519842-12791463-158532 24506-24509 12791463 denotes 106
32519842-22153019-158533 24510-24513 22153019 denotes 110
32519842-22153019-158534 25048-25051 22153019 denotes 110
32519842-21861270-158535 25058-25061 21861270 denotes 111
32519842-27211286-158536 25127-25130 27211286 denotes 113
32519842-22279971-158537 25148-25151 22279971 denotes 114
32519842-31804797-158538 25416-25419 31804797 denotes 116
32519842-31397467-158539 26223-26226 31397467 denotes 107
32519842-32373222-158540 26487-26489 32373222 denotes 57
32519842-28946131-158541 27733-27736 28946131 denotes 119
32519842-20929766-158542 28031-28034 20929766 denotes 120
32519842-21720407-158543 29036-29039 21720407 denotes 121
32519842-1303270-158544 29791-29794 1303270 denotes 122
32519842-25022906-158545 30606-30607 25022906 denotes 5
32519842-27213956-158546 31600-31603 27213956 denotes 123
32519842-26982250-158547 32040-32043 26982250 denotes 124
32519842-27575283-158548 32735-32737 27575283 denotes 32
32519842-20394070-158549 33036-33039 20394070 denotes 125
32519842-24430614-158550 33629-33632 24430614 denotes 126
32519842-21104827-158551 33897-33900 21104827 denotes 127
32519842-29251725-158552 34193-34195 29251725 denotes 53
32519842-32333836-158553 34658-34660 32333836 denotes 21
32519842-32286790-158554 34900-34903 32286790 denotes 129
32519842-30310233-158555 35406-35409 30310233 denotes 132
32519842-32305088-158556 36452-36455 32305088 denotes 134
32519842-32305088-158557 37162-37165 32305088 denotes 134
32519842-31065337-158558 37524-37527 31065337 denotes 139