PMC:7295558 / 1797-3008 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T20","span":{"begin":127,"end":138},"obj":"NCBITaxon:11118"},{"id":"T21","span":{"begin":153,"end":161},"obj":"SP_7"},{"id":"T22","span":{"begin":186,"end":197},"obj":"NCBITaxon:11118"},{"id":"T23","span":{"begin":198,"end":210},"obj":"SP_7"},{"id":"T24","span":{"begin":211,"end":222},"obj":"SP_7;UBERON:0001004"},{"id":"T25","span":{"begin":223,"end":245},"obj":"SP_7"},{"id":"T26","span":{"begin":247,"end":257},"obj":"SP_7"},{"id":"T27","span":{"begin":369,"end":377},"obj":"SP_7"},{"id":"T28","span":{"begin":546,"end":554},"obj":"SP_7"},{"id":"T29","span":{"begin":587,"end":598},"obj":"UBERON:0001004"},{"id":"T30","span":{"begin":707,"end":728},"obj":"UBERON:0004535"},{"id":"T31","span":{"begin":836,"end":850},"obj":"UBERON:0004535"},{"id":"T32","span":{"begin":913,"end":926},"obj":"UBERON:0000948"},{"id":"T33","span":{"begin":977,"end":987},"obj":"UBERON:0002349"},{"id":"T34","span":{"begin":1047,"end":1063},"obj":"UBERON:0002084"},{"id":"T35","span":{"begin":1202,"end":1210},"obj":"SP_7"},{"id":"T20851","span":{"begin":127,"end":138},"obj":"NCBITaxon:11118"},{"id":"T97341","span":{"begin":153,"end":161},"obj":"SP_7"},{"id":"T61228","span":{"begin":186,"end":197},"obj":"NCBITaxon:11118"},{"id":"T9029","span":{"begin":198,"end":210},"obj":"SP_7"},{"id":"T75673","span":{"begin":211,"end":222},"obj":"SP_7;UBERON:0001004"},{"id":"T36620","span":{"begin":223,"end":245},"obj":"SP_7"},{"id":"T18134","span":{"begin":247,"end":257},"obj":"SP_7"},{"id":"T33325","span":{"begin":369,"end":377},"obj":"SP_7"},{"id":"T75404","span":{"begin":546,"end":554},"obj":"SP_7"},{"id":"T53069","span":{"begin":587,"end":598},"obj":"UBERON:0001004"},{"id":"T43876","span":{"begin":707,"end":728},"obj":"UBERON:0004535"},{"id":"T85327","span":{"begin":836,"end":850},"obj":"UBERON:0004535"},{"id":"T80970","span":{"begin":913,"end":926},"obj":"UBERON:0000948"},{"id":"T33822","span":{"begin":977,"end":987},"obj":"UBERON:0002349"},{"id":"T16632","span":{"begin":1047,"end":1063},"obj":"UBERON:0002084"},{"id":"T7327","span":{"begin":1202,"end":1210},"obj":"SP_7"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T3","span":{"begin":707,"end":728},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma7161"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T4","span":{"begin":707,"end":728},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0004535"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T12","span":{"begin":46,"end":55},"obj":"Disease"},{"id":"T13","span":{"begin":127,"end":151},"obj":"Disease"},{"id":"T14","span":{"begin":153,"end":161},"obj":"Disease"},{"id":"T15","span":{"begin":198,"end":245},"obj":"Disease"},{"id":"T16","span":{"begin":198,"end":231},"obj":"Disease"},{"id":"T17","span":{"begin":247,"end":255},"obj":"Disease"},{"id":"T18","span":{"begin":369,"end":377},"obj":"Disease"},{"id":"T19","span":{"begin":546,"end":554},"obj":"Disease"},{"id":"T20","span":{"begin":836,"end":864},"obj":"Disease"},{"id":"T21","span":{"begin":1202,"end":1210},"obj":"Disease"}],"attributes":[{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A18","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A19","pred":"mondo_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0004995"},{"id":"A21","pred":"mondo_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T15","span":{"begin":18,"end":19},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T16","span":{"begin":263,"end":266},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T17","span":{"begin":315,"end":316},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T18","span":{"begin":338,"end":340},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T19","span":{"begin":647,"end":650},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T20","span":{"begin":707,"end":728},"obj":"http://purl.obolibrary.org/obo/UBERON_0004535"},{"id":"T21","span":{"begin":707,"end":728},"obj":"http://www.ebi.ac.uk/efo/EFO_0000791"},{"id":"T22","span":{"begin":883,"end":886},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T23","span":{"begin":887,"end":888},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T5","span":{"begin":181,"end":185},"obj":"Chemical"},{"id":"T6","span":{"begin":877,"end":882},"obj":"Chemical"}],"attributes":[{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_10545"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-sentences","denotations":[{"id":"T22","span":{"begin":0,"end":112},"obj":"Sentence"},{"id":"T23","span":{"begin":113,"end":341},"obj":"Sentence"},{"id":"T24","span":{"begin":342,"end":536},"obj":"Sentence"},{"id":"T25","span":{"begin":537,"end":735},"obj":"Sentence"},{"id":"T26","span":{"begin":736,"end":912},"obj":"Sentence"},{"id":"T27","span":{"begin":913,"end":1129},"obj":"Sentence"},{"id":"T28","span":{"begin":1130,"end":1211},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T6","span":{"begin":46,"end":55},"obj":"Phenotype"},{"id":"T7","span":{"begin":836,"end":858},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0001626"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"LitCovid-PubTator","denotations":[{"id":"54","span":{"begin":181,"end":197},"obj":"Species"},{"id":"55","span":{"begin":198,"end":245},"obj":"Species"},{"id":"56","span":{"begin":247,"end":257},"obj":"Species"},{"id":"57","span":{"begin":573,"end":581},"obj":"Species"},{"id":"58","span":{"begin":816,"end":824},"obj":"Species"},{"id":"59","span":{"begin":1188,"end":1196},"obj":"Species"},{"id":"60","span":{"begin":46,"end":55},"obj":"Disease"},{"id":"61","span":{"begin":127,"end":151},"obj":"Disease"},{"id":"62","span":{"begin":153,"end":161},"obj":"Disease"},{"id":"63","span":{"begin":369,"end":377},"obj":"Disease"},{"id":"64","span":{"begin":546,"end":554},"obj":"Disease"},{"id":"65","span":{"begin":587,"end":607},"obj":"Disease"},{"id":"66","span":{"begin":836,"end":858},"obj":"Disease"},{"id":"67","span":{"begin":860,"end":863},"obj":"Disease"},{"id":"68","span":{"begin":970,"end":994},"obj":"Disease"},{"id":"69","span":{"begin":1202,"end":1210},"obj":"Disease"}],"attributes":[{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Tax:694002"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"Tax:2697049"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"Tax:2697049"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"Tax:9606"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"Tax:9606"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"Tax:9606"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D011014"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:C000657245"},{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"MESH:C000657245"},{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"MESH:C000657245"},{"id":"A64","pred":"tao:has_database_id","subj":"64","obj":"MESH:C000657245"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"MESH:D012818"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"MESH:D002318"},{"id":"A67","pred":"tao:has_database_id","subj":"67","obj":"MESH:D002318"},{"id":"A68","pred":"tao:has_database_id","subj":"68","obj":"MESH:D009202"},{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}

{"project":"2_test","denotations":[{"id":"32595812-32031570-18405858","span":{"begin":106,"end":107},"obj":"32031570"},{"id":"32595812-32015507-18405859","span":{"begin":109,"end":110},"obj":"32015507"},{"id":"32595812-32091533-18405860","span":{"begin":533,"end":534},"obj":"32091533"},{"id":"32595812-31986264-18405861","span":{"begin":730,"end":731},"obj":"31986264"},{"id":"32595812-32211816-18405861","span":{"begin":730,"end":731},"obj":"32211816"},{"id":"32595812-32139904-18405862","span":{"begin":909,"end":910},"obj":"32139904"},{"id":"32595812-30627581-18405863","span":{"begin":1126,"end":1127},"obj":"30627581"}],"text":"In December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with COVID-19."}