PMC:7291971 / 34260-35429
Annnotations
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T720 | 34-42 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T721 | 47-55 | CHEBI:33893;CHEBI:33893 | denotes | reagents |
| T722 | 165-172 | CHEBI:29320;CHEBI:29320 | denotes | calcium |
| T723 | 173-180 | CHEBI:29239;CHEBI:29239 | denotes | hydride |
| T724 | 243-249 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T725 | 911-918 | CHEBI:46787;CHEBI:46787 | denotes | solvent |
| T726 | 980-985 | CHEBI:1418;CHEBI:1418 | denotes | CH3CN |
| T727 | 1089-1098 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T86649 | 34-42 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T43192 | 47-55 | CHEBI:33893;CHEBI:33893 | denotes | reagents |
| T3261 | 165-172 | CHEBI:29320;CHEBI:29320 | denotes | calcium |
| T10589 | 173-180 | CHEBI:29239;CHEBI:29239 | denotes | hydride |
| T99839 | 243-249 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T52140 | 911-918 | CHEBI:46787;CHEBI:46787 | denotes | solvent |
| T30031 | 980-985 | CHEBI:1418;CHEBI:1418 | denotes | CH3CN |
| T39091 | 1089-1098 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 561 | 141-145 | Chemical | denotes | DIEA | |
| 562 | 165-180 | Chemical | denotes | calcium hydride | |
| 563 | 243-249 | Chemical | denotes | silica | MESH:D012822 |
| 564 | 773-786 | Chemical | denotes | Dinucleosides | |
| 565 | 941-946 | Chemical | denotes | CH3CN | |
| 566 | 958-963 | Chemical | denotes | TEAAc | |
| 567 | 980-985 | Chemical | denotes | CH3CN | |
| 568 | 997-1002 | Chemical | denotes | TEEAc | |
| 569 | 469-473 | Disease | denotes | HRMS |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T98 | 679-682 | Disease | denotes | LPG | http://purl.obolibrary.org/obo/MONDO_0012725 |
| T99 | 761-764 | Disease | denotes | TCC | http://purl.obolibrary.org/obo/MONDO_0008521 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T255 | 552-553 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T256 | 617-618 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T257 | 677-678 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T258 | 696-697 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T259 | 787-791 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 1–16 |
| T260 | 820-821 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T261 | 843-845 | http://purl.obolibrary.org/obo/CLO_0002878 | denotes | ec |
| T262 | 972-973 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T263 | 1011-1012 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T264 | 1099-1103 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 1–16 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T564 | 34-42 | Chemical | denotes | solvents | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T565 | 47-55 | Chemical | denotes | reagents | http://purl.obolibrary.org/obo/CHEBI_33893 |
| T566 | 165-172 | Chemical | denotes | calcium | http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320 |
| T568 | 173-180 | Chemical | denotes | hydride | http://purl.obolibrary.org/obo/CHEBI_29239 |
| T569 | 243-249 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T570 | 679-682 | Chemical | denotes | LPG | http://purl.obolibrary.org/obo/CHEBI_59681 |
| T571 | 761-764 | Chemical | denotes | TCC | http://purl.obolibrary.org/obo/CHEBI_48347 |
| T572 | 809-811 | Chemical | denotes | RP | http://purl.obolibrary.org/obo/CHEBI_141419 |
| T573 | 911-918 | Chemical | denotes | solvent | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T574 | 965-971 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T575 | 1004-1010 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T45 | 1157-1168 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T246 | 0-25 | Sentence | denotes | 4.1.1 General procedures |
| T247 | 26-140 | Sentence | denotes | All dry solvents and reagents were purchased from commercial suppliers and were used without further purification. |
| T248 | 141-181 | Sentence | denotes | DIEA was distilled over calcium hydride. |
| T249 | 182-264 | Sentence | denotes | Thin-layer chromatography (TLC) analyses were carried out on silica plate 60 F254. |
| T250 | 265-384 | Sentence | denotes | Purifications by column chromatography were performed using Biotage Isolera 1 system with FlashPure cartridges (Buchi). |
| T251 | 385-468 | Sentence | denotes | NMR experiments were recorded on Bruker 400, 500 or 600 MHz spectrometers at 20 °C. |
| T252 | 469-583 | Sentence | denotes | HRMS analyses were obtained with electrospray ionization (ESI) in positive mode on a Q-TOF Micromass spectrometer. |
| T253 | 584-772 | Sentence | denotes | Analytical HPLC was performed on a UHPLC Thermoscientific Ultimate 3000 system equipped with a LPG-3400RS pump, a DAD 3000 detector and an WPS-3000TBRS Autosampler, Column Oven TCC-3000SD. |
| T254 | 773-891 | Sentence | denotes | Dinucleosides 1–16 were analyzed by RP-HPLC on a Column Nucleodur C18 ec 100-3, 4.6 × 75 mm (Macherey Nagel) at 30 °C. |
| T255 | 892-937 | Sentence | denotes | The following HPLC solvent systems were used: |
| T256 | 938-1014 | Sentence | denotes | 1% CH3CN in 12.5 mM TEAAc (buffer A), 80% CH3CN in 12.5 mM TEEAc (buffer B). |
| T257 | 1015-1038 | Sentence | denotes | Flow rate was 1 mL/min. |
| T258 | 1039-1076 | Sentence | denotes | UV detection was performed at 260 nm. |
| T259 | 1077-1169 | Sentence | denotes | Lyophilized compounds 1–16 were stored at −20 °C for several months without any degradation. |