PMC:7291971 / 24444-25169
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T536 | 52-61 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
T537 | 65-73 | SP_10 | denotes | SARS-CoV |
T538 | 84-89 | SP_6;NCBITaxon:9606 | denotes | human |
T539 | 126-131 | PR:000000125 | denotes | nsp14 |
T31576 | 92-101 | CHEBI:36357;CHEBI:36357 | denotes | MT activi |
T67246 | 129-137 | SP_10 | denotes | 14 IC50a |
T8618 | 138-143 | PR:000000125 | denotes | (μM) |
T22326 | 181-190 | CHEBI:35222;CHEBI:35222 | denotes | 2 40.6 ± |
T4976 | 238-246 | SP_10 | denotes | 0 10 3.9 |
T14252 | 289-298 | CHEBI:36357;CHEBI:36357 | denotes | .7 ± 0.5 |
T88128 | 382-391 | CHEBI:35222;CHEBI:35222 | denotes | 9 n.d a C |
T62427 | 471-480 | CHEBI:35222;CHEBI:35222 | denotes | experime |
T17572 | 520-528 | SP_10 | denotes | The MTas |
T56144 | 715-723 | CHEBI:36357;CHEBI:36357 | denotes | at 50 μ |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T66 | 65-73 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T67 | 117-125 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T203 | 45-51 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
T204 | 84-89 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T205 | 95-105 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
T206 | 258-260 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T207 | 388-389 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T208 | 421-429 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T209 | 485-486 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T210 | 515-517 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T211 | 530-538 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T212 | 582-583 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32563813-28676301-29105588 | 515-517 | 28676301 | denotes | 11 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T168 | 0-106 | Sentence | denotes | Table 2 Comparison of IC50 values of 10 most active compounds on SARS-CoV nsp14 and human RNMT activities. |
T169 | 107-157 | Sentence | denotes | Compounds SARS-CoV nsp14 IC50a (μM) hRNMTIC50 (μM) |
T170 | 158-180 | Sentence | denotes | Sinefunginb 0.36 <0.05 |
T171 | 181-204 | Sentence | denotes | 2 40.6 ± 3.2 10.9 ± 1.0 |
T172 | 205-222 | Sentence | denotes | 6 55.5 ± 5.1 >500 |
T173 | 223-239 | Sentence | denotes | 9 2.6 ± 0.2 >500 |
T174 | 240-257 | Sentence | denotes | 10 3.9 ± 0.4 >500 |
T175 | 258-284 | Sentence | denotes | 11 70.4 ± 4.9 169.3 ± 30.4 |
T176 | 285-310 | Sentence | denotes | 12 5.7 ± 0.5 275.9 ± 28.7 |
T177 | 311-336 | Sentence | denotes | 13 0.6 ± 0.1 247.5 ± 14.9 |
T178 | 337-353 | Sentence | denotes | 14 1.5 ± 0.1 n.d |
T179 | 354-370 | Sentence | denotes | 15 2.4 ± 0.2 n.i |
T180 | 371-387 | Sentence | denotes | 16 9.9 ± 0.9 n.d |
T181 | 388-484 | Sentence | denotes | a Concentration inhibiting MTase activity by 50%; mean value from three independent experiments. |
T182 | 485-519 | Sentence | denotes | b values from the literature [11]. |
T183 | 520-725 | Sentence | denotes | The MTase activity for IC50 determinations was measured using a filter binding assay as described above. n.i: no inhibition detected at 50 μM; n.d: not determined due to inhibition lower than 50% at 50 μM. |
MyTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32563813-28676301-29105588 | 515-517 | 28676301 | denotes | 11 |