PMC:7291971 / 1049-1316 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T18","span":{"begin":34,"end":43},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T19","span":{"begin":94,"end":106},"obj":"NCBITaxon:31032"},{"id":"T20","span":{"begin":110,"end":118},"obj":"SP_10"},{"id":"T21","span":{"begin":200,"end":208},"obj":"SP_10"},{"id":"T7397","span":{"begin":34,"end":43},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T53306","span":{"begin":94,"end":106},"obj":"NCBITaxon:31032"},{"id":"T48802","span":{"begin":110,"end":118},"obj":"SP_10"},{"id":"T86425","span":{"begin":200,"end":208},"obj":"SP_10"}],"text":"Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar range."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T4","span":{"begin":110,"end":118},"obj":"Disease"},{"id":"T5","span":{"begin":200,"end":208},"obj":"Disease"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar range."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T6","span":{"begin":56,"end":62},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar range."}

{"project":"LitCovid-sentences","denotations":[{"id":"T9","span":{"begin":0,"end":267},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar range."}