PMC:7289100 / 7260-9354
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T29 | 123-136 | Body_part | denotes | cranial nerve | http://purl.org/sig/ont/fma/fma5865 |
| T30 | 235-245 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
| T31 | 368-371 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T32 | 581-594 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
| T33 | 603-615 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T34 | 623-648 | Body_part | denotes | peripheral nervous system | http://purl.org/sig/ont/fma/fma9903 |
| T35 | 831-843 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T36 | 1103-1113 | Body_part | denotes | lower-limb | http://purl.org/sig/ont/fma/fma7184 |
| T37 | 1371-1382 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T38 | 1505-1511 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T10 | 123-136 | Body_part | denotes | cranial nerve | http://purl.obolibrary.org/obo/UBERON_0001785 |
| T11 | 131-136 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T12 | 581-594 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
| T13 | 623-648 | Body_part | denotes | peripheral nervous system | http://purl.obolibrary.org/obo/UBERON_0000010 |
| T14 | 634-648 | Body_part | denotes | nervous system | http://purl.obolibrary.org/obo/UBERON_0001016 |
| T15 | 1109-1113 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T103 | 0-3 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T104 | 246-256 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T105 | 295-305 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T106 | 314-323 | Disease | denotes | Influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T107 | 325-334 | Disease | denotes | Chlamydia | http://purl.obolibrary.org/obo/MONDO_0005701 |
| T108 | 341-350 | Disease | denotes | varicella | http://purl.obolibrary.org/obo/MONDO_0005700 |
| T109 | 352-357 | Disease | denotes | mumps | http://purl.obolibrary.org/obo/MONDO_0000989 |
| T110 | 359-366 | Disease | denotes | rubella | http://purl.obolibrary.org/obo/MONDO_0004656 |
| T111 | 373-378 | Disease | denotes | Polio | http://purl.obolibrary.org/obo/MONDO_0017373 |
| T112 | 380-391 | Disease | denotes | Hepatitis E | http://purl.obolibrary.org/obo/MONDO_0005788 |
| T113 | 380-389 | Disease | denotes | Hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T114 | 393-401 | Disease | denotes | Borrelia | http://purl.obolibrary.org/obo/MONDO_0019632 |
| T115 | 403-423 | Disease | denotes | Mycoplasma pneumonia | http://purl.obolibrary.org/obo/MONDO_0005867 |
| T116 | 414-423 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T117 | 457-460 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T118 | 548-567 | Disease | denotes | autoimmune disorder | http://purl.obolibrary.org/obo/MONDO_0007179 |
| T119 | 688-691 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T120 | 717-726 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T121 | 1184-1190 | Disease | denotes | ataxia | http://purl.obolibrary.org/obo/MONDO_0000437 |
| T122 | 1245-1256 | Disease | denotes | tetraplegia | http://purl.obolibrary.org/obo/MONDO_0001590 |
| T123 | 1847-1850 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T124 | 1950-1953 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T125 | 1989-1997 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T126 | 1989-1993 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T70 | 7-8 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T71 | 53-58 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limbs |
| T72 | 131-136 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T73 | 235-245 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
| T74 | 235-245 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
| T75 | 581-594 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T76 | 623-648 | http://purl.obolibrary.org/obo/UBERON_0000010 | denotes | peripheral nervous system |
| T77 | 623-648 | http://www.ebi.ac.uk/efo/EFO_0000891 | denotes | peripheral nervous system |
| T78 | 858-859 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T79 | 1109-1113 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
| T80 | 1270-1271 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T81 | 1282-1284 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T82 | 1505-1511 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T83 | 1560-1561 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T84 | 1574-1578 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
| T85 | 1574-1578 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
| T86 | 1688-1689 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T87 | 1941-1942 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T37 | 603-615 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T38 | 831-843 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T39 | 1371-1382 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T40 | 1574-1578 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
| T41 | 1788-1806 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T42 | 1808-1817 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T53 | 59-68 | Phenotype | denotes | paralysis | http://purl.obolibrary.org/obo/HP_0003470 |
| T54 | 81-90 | Phenotype | denotes | areflexia | http://purl.obolibrary.org/obo/HP_0001284 |
| T55 | 94-106 | Phenotype | denotes | hyporeflexia | http://purl.obolibrary.org/obo/HP_0001265 |
| T56 | 123-148 | Phenotype | denotes | cranial nerve involvement | http://purl.obolibrary.org/obo/HP_0001291 |
| T57 | 380-389 | Phenotype | denotes | Hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T58 | 414-423 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T59 | 548-567 | Phenotype | denotes | autoimmune disorder | http://purl.obolibrary.org/obo/HP_0002960 |
| T60 | 1103-1122 | Phenotype | denotes | lower-limb weakness | http://purl.obolibrary.org/obo/HP_0007340 |
| T61 | 1127-1138 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
| T62 | 1156-1171 | Phenotype | denotes | facial diplegia | http://purl.obolibrary.org/obo/HP_0001349 |
| T63 | 1184-1190 | Phenotype | denotes | ataxia | http://purl.obolibrary.org/obo/HP_0001251 |
| T64 | 1195-1206 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
| T65 | 1229-1241 | Phenotype | denotes | tetraparesis | http://purl.obolibrary.org/obo/HP_0002273 |
| T66 | 1245-1256 | Phenotype | denotes | tetraplegia | http://purl.obolibrary.org/obo/HP_0002445 |
| T67 | 1657-1670 | Phenotype | denotes | quadriparesis | http://purl.obolibrary.org/obo/HP_0002273 |
| T68 | 1701-1706 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T69 | 1708-1713 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T70 | 1718-1725 | Phenotype | denotes | dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 1512-1520 | http://purl.obolibrary.org/obo/GO_0015297 | denotes | exchange |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T38 | 0-187 | Sentence | denotes | GBS is a progressive, ascending, symmetrical flaccid limbs paralysis, along with areflexia or hyporeflexia with or without cranial nerve involvement which can progress over days to weeks. |
| T39 | 188-273 | Sentence | denotes | The disease may be triggered by respiratory or intestinal infections or vaccinations. |
| T40 | 274-456 | Sentence | denotes | The known triggering infections include Influenza; Chlamydia; CMV; varicella; mumps; rubella; HIV; Polio; Hepatitis E; Borrelia; Mycoplasma pneumonia as well as Campilobacter Jejuni. |
| T41 | 457-657 | Sentence | denotes | GBS is an immune-mediated disorder with molecular mimicry playing an important role in its autoimmune disorder in which the immune system attacks gangliosides on the peripheral nervous system [34,35]. |
| T42 | 658-735 | Sentence | denotes | There are so far 2 reports of GBS associated with Covid-19 infection [36,37]. |
| T43 | 736-844 | Sentence | denotes | It is yet unclear whether Covid-19 induces the production of antibodies against these specific gangliosides. |
| T44 | 845-980 | Sentence | denotes | The first is a report of five out of 1200 patients hospitalized between February 28th and March 21st, 2020 in Northern Italy hospitals. |
| T45 | 981-1071 | Sentence | denotes | The onset of neurological symptoms began 7–10 days after the initial respiratory symptoms. |
| T46 | 1072-1207 | Sentence | denotes | Four out of the 5 patients had lower-limb weakness and paresthesia and one was with facial diplegia followed by ataxia and paresthesia. |
| T47 | 1208-1318 | Sentence | denotes | Generalized, flaccid tetraparesis or tetraplegia evolved over a period of 36 h to 4 days in 4 of the patients. |
| T48 | 1319-1365 | Sentence | denotes | Three of them required mechanical ventilation. |
| T49 | 1366-1427 | Sentence | denotes | Anti-ganglioside antibodies were either negative or not done. |
| T50 | 1428-1521 | Sentence | denotes | All patients received IVIG (1 of then required 2 cycles) and one had started plasma exchange. |
| T51 | 1522-1726 | Sentence | denotes | The second report from Iran describes a 65 year old male patient admitted to hospital because of acute progressive symmetric ascending quadriparesis, two weeks after a history of cough, fever and dyspnea. |
| T52 | 1727-1760 | Sentence | denotes | Covid-19 was diagnosed by RT-PCR. |
| T53 | 1761-1846 | Sentence | denotes | The patient was treated by hydroxychloroquine, Lopinavir/Ritonavir, and Azithromycin. |
| T54 | 1847-1872 | Sentence | denotes | GBS was confirmed by EMG. |
| T55 | 1873-1916 | Sentence | denotes | The patient was treated by IVIG for 5 days. |
| T56 | 1917-2094 | Sentence | denotes | Another early report of a single GBS patient came from China during the SARS-CoV-2 epidemic, although there is some concern regarding the causality in this particular case [38]. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T135 | 53-58 | UBERON:0002101 | denotes | limbs |
| T136 | 123-136 | UBERON:0001785 | denotes | cranial nerve |
| T137 | 220-231 | UBERON:0001004 | denotes | respiratory |
| T138 | 235-245 | UBERON:0000160 | denotes | intestinal |
| T139 | 325-334 | NCBITaxon:810 | denotes | Chlamydia |
| T140 | 336-339 | NCBITaxon:10358 | denotes | CMV |
| T141 | 359-366 | NCBITaxon:31033 | denotes | rubella |
| T142 | 393-401 | NCBITaxon:138 | denotes | Borrelia |
| T143 | 403-413 | NCBITaxon:2093 | denotes | Mycoplasma |
| T144 | 467-473 | UBERON:0002405 | denotes | immune |
| T145 | 548-558 | UBERON:0002405 | denotes | autoimmune |
| T146 | 581-594 | UBERON:0002405 | denotes | immune system |
| T147 | 603-615 | CHEBI:16856;CHEBI:16856 | denotes | gangliosides |
| T148 | 623-648 | UBERON:0000010 | denotes | peripheral nervous system |
| T149 | 708-716 | SP_7 | denotes | Covid-19 |
| T150 | 762-770 | SP_7 | denotes | Covid-19 |
| T151 | 797-807 | GO:0042571 | denotes | antibodies |
| T152 | 831-843 | CHEBI:28892;CHEBI:28892 | denotes | gangliosides |
| T153 | 994-1006 | UBERON:0001016 | denotes | neurological |
| T154 | 1050-1061 | UBERON:0001004 | denotes | respiratory |
| T155 | 1109-1113 | UBERON:0002103 | denotes | limb |
| T156 | 1156-1162 | UBERON:0001456 | denotes | facial |
| T157 | 1371-1382 | CHEBI:28892;CHEBI:28892 | denotes | ganglioside |
| T158 | 1383-1393 | GO:0042571 | denotes | antibodies |
| T159 | 1450-1454 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T160 | 1505-1511 | UBERON:0001969;GO:0030168 | denotes | plasma |
| T161 | 1727-1735 | SP_7 | denotes | Covid-19 |
| T162 | 1788-1806 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T163 | 1808-1817 | DG_23 | denotes | Lopinavir |
| T164 | 1818-1827 | DG_30 | denotes | Ritonavir |
| T165 | 1833-1845 | CHEBI:28619;DG_6;CHEBI:28619 | denotes | Azithromycin |
| T166 | 1900-1904 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T167 | 1989-1999 | SP_7 | denotes | SARS-CoV-2 |
| T61735 | 53-58 | UBERON:0002101 | denotes | limbs |
| T34156 | 123-136 | UBERON:0001785 | denotes | cranial nerve |
| T56150 | 220-231 | UBERON:0001004 | denotes | respiratory |
| T26041 | 235-245 | UBERON:0000160 | denotes | intestinal |
| T5537 | 325-334 | NCBITaxon:810 | denotes | Chlamydia |
| T47372 | 336-339 | NCBITaxon:10358 | denotes | CMV |
| T86481 | 359-366 | NCBITaxon:31033 | denotes | rubella |
| T32318 | 393-401 | NCBITaxon:138 | denotes | Borrelia |
| T34988 | 403-413 | NCBITaxon:2093 | denotes | Mycoplasma |
| T84577 | 467-473 | UBERON:0002405 | denotes | immune |
| T7940 | 548-558 | UBERON:0002405 | denotes | autoimmune |
| T69529 | 581-594 | UBERON:0002405 | denotes | immune system |
| T63033 | 603-615 | CHEBI:16856;CHEBI:16856 | denotes | gangliosides |
| T86657 | 623-648 | UBERON:0000010 | denotes | peripheral nervous system |
| T10423 | 708-716 | SP_7 | denotes | Covid-19 |
| T75493 | 762-770 | SP_7 | denotes | Covid-19 |
| T35763 | 797-807 | GO:0042571 | denotes | antibodies |
| T7962 | 831-843 | CHEBI:28892;CHEBI:28892 | denotes | gangliosides |
| T34902 | 994-1006 | UBERON:0001016 | denotes | neurological |
| T98751 | 1050-1061 | UBERON:0001004 | denotes | respiratory |
| T41824 | 1109-1113 | UBERON:0002103 | denotes | limb |
| T29107 | 1156-1162 | UBERON:0001456 | denotes | facial |
| T58767 | 1371-1382 | CHEBI:28892;CHEBI:28892 | denotes | ganglioside |
| T17970 | 1383-1393 | GO:0042571 | denotes | antibodies |
| T23017 | 1450-1454 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T59182 | 1505-1511 | UBERON:0001969;GO:0030168 | denotes | plasma |
| T99347 | 1727-1735 | SP_7 | denotes | Covid-19 |
| T13154 | 1788-1806 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T39287 | 1808-1817 | DG_23 | denotes | Lopinavir |
| T73644 | 1818-1827 | DG_30 | denotes | Ritonavir |
| T88345 | 1833-1845 | CHEBI:28619;DG_6;CHEBI:28619 | denotes | Azithromycin |
| T35837 | 1900-1904 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T3374 | 1989-1999 | SP_7 | denotes | SARS-CoV-2 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 267 | 887-895 | Species | denotes | patients | Tax:9606 |
| 268 | 1090-1098 | Species | denotes | patients | Tax:9606 |
| 269 | 1309-1317 | Species | denotes | patients | Tax:9606 |
| 270 | 1432-1440 | Species | denotes | patients | Tax:9606 |
| 271 | 1579-1586 | Species | denotes | patient | Tax:9606 |
| 272 | 1765-1772 | Species | denotes | patient | Tax:9606 |
| 273 | 1877-1884 | Species | denotes | patient | Tax:9606 |
| 274 | 1954-1961 | Species | denotes | patient | Tax:9606 |
| 275 | 1989-1999 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 276 | 368-371 | Species | denotes | HIV | Tax:12721 |
| 277 | 0-3 | Chemical | denotes | GBS | |
| 278 | 457-460 | Chemical | denotes | GBS | |
| 279 | 603-615 | Chemical | denotes | gangliosides | MESH:D005732 |
| 280 | 688-691 | Chemical | denotes | GBS | |
| 281 | 831-843 | Chemical | denotes | gangliosides | MESH:D005732 |
| 282 | 1371-1382 | Chemical | denotes | ganglioside | MESH:D005732 |
| 283 | 1788-1806 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 284 | 1808-1827 | Chemical | denotes | Lopinavir/Ritonavir | MESH:C558899 |
| 285 | 1833-1845 | Chemical | denotes | Azithromycin | MESH:D017963 |
| 286 | 1847-1850 | Chemical | denotes | GBS | |
| 287 | 1950-1953 | Chemical | denotes | GBS | |
| 288 | 59-68 | Disease | denotes | paralysis | MESH:D010243 |
| 289 | 81-106 | Disease | denotes | areflexia or hyporeflexia | MESH:D012021 |
| 290 | 220-256 | Disease | denotes | respiratory or intestinal infections | MESH:D012141 |
| 291 | 295-305 | Disease | denotes | infections | MESH:D007239 |
| 292 | 359-366 | Disease | denotes | rubella | MESH:D012409 |
| 293 | 380-391 | Disease | denotes | Hepatitis E | MESH:D016751 |
| 294 | 414-423 | Disease | denotes | pneumonia | MESH:D011014 |
| 295 | 548-567 | Disease | denotes | autoimmune disorder | MESH:D001327 |
| 296 | 708-716 | Disease | denotes | Covid-19 | MESH:C000657245 |
| 297 | 717-726 | Disease | denotes | infection | MESH:D007239 |
| 298 | 762-770 | Disease | denotes | Covid-19 | MESH:C000657245 |
| 299 | 994-1015 | Disease | denotes | neurological symptoms | MESH:D009422 |
| 300 | 1050-1070 | Disease | denotes | respiratory symptoms | MESH:D012818 |
| 301 | 1103-1122 | Disease | denotes | lower-limb weakness | MESH:D018908 |
| 302 | 1156-1171 | Disease | denotes | facial diplegia | MESH:C531747 |
| 303 | 1184-1190 | Disease | denotes | ataxia | MESH:D001259 |
| 304 | 1221-1256 | Disease | denotes | flaccid tetraparesis or tetraplegia | MESH:D011782 |
| 305 | 1657-1670 | Disease | denotes | quadriparesis | MESH:D011782 |
| 306 | 1701-1706 | Disease | denotes | cough | MESH:D003371 |
| 307 | 1708-1713 | Disease | denotes | fever | MESH:D005334 |
| 308 | 1718-1725 | Disease | denotes | dyspnea | MESH:D004417 |
| 309 | 1727-1735 | Disease | denotes | Covid-19 | MESH:C000657245 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32535093-20890797-4828861 | 650-652 | 20890797 | denotes | 34 |
| 32535093-8634515-4828862 | 653-655 | 8634515 | denotes | 35 |
| 32535093-32246917-4828863 | 2090-2092 | 32246917 | denotes | 38 |