> top > docs > PMC:7289100 > spans > 19547-23657 > annotations

PMC:7289100 / 19547-23657 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T70 712-716 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163
T71 929-933 Body_part denotes lips http://purl.org/sig/ont/fma/fma59815
T72 990-1000 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T73 1029-1037 Body_part denotes troponin http://purl.org/sig/ont/fma/fma62338
T74 1156-1171 Body_part denotes coronary artery http://purl.org/sig/ont/fma/fma49893
T75 2652-2656 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163
T76 2702-2711 Body_part denotes extremity http://purl.org/sig/ont/fma/fma7182
T77 3091-3098 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T78 3247-3255 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T32 712-716 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014
T33 1156-1171 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T34 1165-1171 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T35 2652-2656 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014
T36 2981-2997 Body_part denotes coronary vessels http://purl.obolibrary.org/obo/UBERON_0005985
T37 2990-2997 Body_part denotes vessels http://purl.obolibrary.org/obo/UBERON_0000055

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T273 71-75 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T274 183-191 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T275 236-245 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T276 551-554 Disease denotes KSS http://purl.obolibrary.org/obo/MONDO_0010787
T277 702-710 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T278 712-721 Disease denotes skin rash http://purl.obolibrary.org/obo/MONDO_0006547
T279 892-906 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T280 1095-1106 Disease denotes myocarditis http://purl.obolibrary.org/obo/MONDO_0004496
T281 1156-1185 Disease denotes coronary artery abnormalities http://purl.obolibrary.org/obo/MONDO_0001389
T282 1214-1230 Disease denotes Kawasaki disease http://purl.obolibrary.org/obo/MONDO_0012727
T283 1457-1465 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T284 1627-1630 Disease denotes KSS http://purl.obolibrary.org/obo/MONDO_0010787
T285 1651-1659 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T286 2122-2134 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T287 2156-2158 Disease denotes KD http://purl.obolibrary.org/obo/MONDO_0012727
T288 2458-2461 Disease denotes KSS http://purl.obolibrary.org/obo/MONDO_0010787
T289 2652-2661 Disease denotes skin rash http://purl.obolibrary.org/obo/MONDO_0006547
T290 2663-2677 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T291 3309-3313 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T292 3671-3679 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T293 3671-3675 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T294 3682-3691 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T295 3916-3924 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T296 4079-4087 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T297 4079-4083 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T298 4090-4099 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T299 4106-4108 Disease denotes TS http://purl.obolibrary.org/obo/MONDO_0010979|http://purl.obolibrary.org/obo/MONDO_0016455

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T162 611-614 http://purl.obolibrary.org/obo/CLO_0009715 denotes y/o
T163 621-622 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 712-716 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T165 712-716 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T166 712-716 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T167 712-716 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T168 712-716 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T169 1165-1171 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T170 1165-1171 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T171 1726-1727 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T172 1773-1774 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T173 2025-2026 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T174 2250-2251 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T175 2424-2425 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T176 2605-2606 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T177 2652-2656 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T178 2652-2656 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T179 2652-2656 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T180 2652-2656 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T181 2652-2656 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T182 2702-2711 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremity
T183 2990-2997 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessels
T184 3021-3022 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T185 3401-3406 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T89 305-310 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T90 1012-1018 Chemical denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708
T91 1046-1049 Chemical denotes BNP http://purl.obolibrary.org/obo/CHEBI_80234
T92 1296-1304 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T93 2156-2158 Chemical denotes KD http://purl.obolibrary.org/obo/CHEBI_73601
T94 3091-3098 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T95 3125-3138 Chemical denotes triglycerides http://purl.obolibrary.org/obo/CHEBI_17855
T96 4106-4108 Chemical denotes TS http://purl.obolibrary.org/obo/CHEBI_73664

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T148 535-540 Phenotype denotes Shock http://purl.obolibrary.org/obo/HP_0031273
T149 658-663 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T150 686-700 Phenotype denotes abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T151 702-710 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T152 712-721 Phenotype denotes skin rash http://purl.obolibrary.org/obo/HP_0000988
T153 787-792 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T154 817-828 Phenotype denotes dehydration http://purl.obolibrary.org/obo/HP_0001944
T155 862-872 Phenotype denotes arthralgia http://purl.obolibrary.org/obo/HP_0002829
T156 874-879 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T157 881-890 Phenotype denotes meningism http://purl.obolibrary.org/obo/HP_0031179
T158 892-906 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T159 1095-1106 Phenotype denotes myocarditis http://purl.obolibrary.org/obo/HP_0012819
T160 1165-1185 Phenotype denotes artery abnormalities http://purl.obolibrary.org/obo/HP_0011004
T161 2056-2061 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T162 2645-2650 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T163 2652-2661 Phenotype denotes skin rash http://purl.obolibrary.org/obo/HP_0000988
T164 2663-2677 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T165 2679-2696 Phenotype denotes peripheral oedema http://purl.obolibrary.org/obo/HP_0012398
T166 2712-2716 Phenotype denotes pain http://purl.obolibrary.org/obo/HP_0012531
T167 2793-2798 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T8 2122-2134 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T126 0-132 Sentence denotes Northern Italy was the first European region to be severely hit by the SARS-COV2 epidemic after the original outbreak in China [67].
T127 133-319 Sentence denotes Although the data on the clinical presentation of COVID-19 in children is still scarce, lower rates of infection and milder forms of disease seem to be typical of this age group [68,69].
T128 320-556 Sentence denotes Since the end of March 2020, we observed and treated or received information from all over Italy about an abnormally elevated number of critically ill patients with clinical characteristics consistent with Kawasaki Shock Syndrome (KSS).
T129 557-829 Sentence denotes The common features were: “middle-aged” children (6–9 y/o) with a history of persistent high spiking fever in the previous days, abdominal pain, diarrhea, skin rash, and rapidly deteriorating clinical conditions with the onset of shock, without clear signs of dehydration.
T130 830-934 Sentence denotes Other less common features were arthralgia, cough, meningism, conjunctivitis and reddened, cracked lips.
T131 935-1057 Sentence denotes Labworks usually showed high inflammatory markers, low lymphocyte count, low sodium, and high troponin and pro-BNP levels.
T132 1058-1186 Sentence denotes Echocardiography was consistent with myocarditis in the majority of patients instead of classical coronary artery abnormalities.
T133 1187-1305 Sentence denotes Patients were diagnosed as Kawasaki disease (typical or incomplete) and treated accordingly with IVIG and/or steroids.
T134 1306-1395 Sentence denotes One patient refractory to such treatments responded successfully to intravenous anakinra.
T135 1396-1581 Sentence denotes Althoug all the patients had family contacts consistent with COVID-19, serology and nasopharyngeal swabs were inconsistently positive both in the single patients and among all children.
T136 1582-1660 Sentence denotes To date we are aware of at least 10 cases of KSS possibly related to COVID-19.
T137 1661-1793 Sentence denotes Given the unprecedented cluster of patients we decided to launch a nationwide alert for pediatricians and start a national registry.
T138 1794-2005 Sentence denotes Few days after the diagnosis of our first cases, news from all over Europe first, and Eastern USA thereafter, reported on the identification of patients with remarkably the same characteristics we have observed.
T139 2006-2222 Sentence denotes Some children with a less severe picture, without shock at the onset, but with clinical characteristics of systemic inflammation and some features of KD have also been seen by us and others (personal communications).
T140 2223-2317 Sentence denotes These observations lead to a variety of nationwide alerts in the respective countries [70,71].
T141 2318-2467 Sentence denotes On May 7, 2020, Riphagen et al. published on 8 patients treated at the South Thames Retrieval Service for a severe acute illness similar to KSS [72].
T142 2468-2583 Sentence denotes Age at presentation was between 4 and 14 years, 6 out of 8 children were of Afro-Caribbean descent and 5 were boys.
T143 2584-2717 Sentence denotes All the children had a similar disease onset with persistent fever, skin rash, conjunctivitis, peripheral oedema, and extremity pain.
T144 2718-2840 Sentence denotes Gastrointestinal symptoms were frequent and severe, all children developed shock requiring ICU admission and vasopressors.
T145 2841-2998 Sentence denotes Another key feature described in those patients was the cardiac involvement, as testified by very elevated cardiac enzymes, and echo-bright coronary vessels.
T146 2999-3047 Sentence denotes One patient developed a giant coronary aneurism.
T147 3048-3153 Sentence denotes Lab works typically showed high C-reactive protein, procalcitonin, ferritin, triglycerides, and D-dimers.
T148 3154-3238 Sentence denotes All children were treated with IVIG (2 g/kg) and 6 also received aspirin (50 mg/kg).
T149 3239-3407 Sentence denotes Broncho-alveolar lavage or nasopharyngeal aspirates were negative for SARS-COV-2 in all children; some of the patients had histories of familial contact with the virus.
T150 3408-3548 Sentence denotes The authors stated that, at the time they were writing their report, another ICU in London managed 20 patients with similar characteristics.
T151 3549-3747 Sentence denotes As per the Royal College of Pediatrics and Child Health (RCPCH) alert, some of these patients resulted to be positive for SARS-CoV-2 infection, by either nasopharyngeal swab, serology, or both [69].
T152 3748-3833 Sentence denotes The New York State Department of Health reported sixty-four cases as of May 5th 2020.
T153 3834-4110 Sentence denotes For the purpose of this review we will refer to this clinical entity as Pediatric COVID-19 Hyperinflammatory Syndrome (PeCOHS), while the English authorities refers to it as Pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection (PIMS-TS).

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T317 71-80 SP_7 denotes SARS-COV2
T318 183-191 SP_7 denotes COVID-19
T319 686-695 UBERON:0000916 denotes abdominal
T320 929-933 UBERON:0001456 denotes lips
T321 990-1000 CL:0000542 denotes lymphocyte
T322 1156-1171 UBERON:0001621 denotes coronary artery
T323 1284-1288 CHEBI:42098;CHEBI:42098 denotes IVIG
T324 1296-1304 CHEBI:35341;CHEBI:35341 denotes steroids
T325 1457-1465 SP_7 denotes COVID-19
T326 1480-1494 UBERON:0001728 denotes nasopharyngeal
T327 1651-1659 SP_7 denotes COVID-19
T328 2718-2734 UBERON:0005409 denotes Gastrointestinal
T329 2897-2904 UBERON:0000948 denotes cardiac
T330 2948-2955 UBERON:0000948 denotes cardiac
T331 2981-2997 UBERON:0005985 denotes coronary vessels
T332 3029-3037 UBERON:0005985 denotes coronary
T333 3080-3098 PR:000005897 denotes C-reactive protein
T334 3125-3138 CHEBI:17855;CHEBI:17855 denotes triglycerides
T335 3185-3189 CHEBI:42098;CHEBI:42098 denotes IVIG
T336 3239-3246 UBERON:0002294 denotes Broncho
T337 3247-3255 UBERON:0003215 denotes alveolar
T338 3266-3280 UBERON:0001728 denotes nasopharyngeal
T339 3309-3319 SP_7 denotes SARS-COV-2
T340 3401-3406 NCBITaxon:10239 denotes virus
T341 3671-3681 SP_7 denotes SARS-CoV-2
T342 3703-3717 UBERON:0001728 denotes nasopharyngeal
T343 3916-3924 SP_7 denotes COVID-19
T344 4031-4042 UBERON:0000467 denotes multisystem
T345 4079-4089 SP_7 denotes SARS-CoV-2
T27311 71-80 SP_7 denotes SARS-COV2
T26890 183-191 SP_7 denotes COVID-19
T73760 686-695 UBERON:0000916 denotes abdominal
T97163 929-933 UBERON:0001456 denotes lips
T94828 990-1000 CL:0000542 denotes lymphocyte
T6045 1156-1171 UBERON:0001621 denotes coronary artery
T40540 1284-1288 CHEBI:42098;CHEBI:42098 denotes IVIG
T4754 1296-1304 CHEBI:35341;CHEBI:35341 denotes steroids
T12082 1457-1465 SP_7 denotes COVID-19
T59721 1480-1494 UBERON:0001728 denotes nasopharyngeal
T28378 1651-1659 SP_7 denotes COVID-19
T30238 2718-2734 UBERON:0005409 denotes Gastrointestinal
T33189 2897-2904 UBERON:0000948 denotes cardiac
T58060 2948-2955 UBERON:0000948 denotes cardiac
T50408 2981-2997 UBERON:0005985 denotes coronary vessels
T30577 3029-3037 UBERON:0005985 denotes coronary
T52588 3080-3098 PR:000005897 denotes C-reactive protein
T34876 3125-3138 CHEBI:17855;CHEBI:17855 denotes triglycerides
T94015 3185-3189 CHEBI:42098;CHEBI:42098 denotes IVIG
T73101 3239-3246 UBERON:0002294 denotes Broncho
T54364 3247-3255 UBERON:0003215 denotes alveolar
T48324 3266-3280 UBERON:0001728 denotes nasopharyngeal
T36886 3309-3319 SP_7 denotes SARS-COV-2
T71001 3401-3406 NCBITaxon:10239 denotes virus
T43948 3671-3681 SP_7 denotes SARS-CoV-2
T86792 3703-3717 UBERON:0001728 denotes nasopharyngeal
T44699 3916-3924 SP_7 denotes COVID-19
T28225 4031-4042 UBERON:0000467 denotes multisystem
T76943 4079-4089 SP_7 denotes SARS-CoV-2

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
743 3080-3098 Gene denotes C-reactive protein Gene:1401
744 71-80 Species denotes SARS-COV2 Tax:2697049
745 195-203 Species denotes children Tax:9606
746 471-479 Species denotes patients Tax:9606
747 597-605 Species denotes children Tax:9606
748 1126-1134 Species denotes patients Tax:9606
749 1187-1195 Species denotes Patients Tax:9606
750 1310-1317 Species denotes patient Tax:9606
751 1412-1420 Species denotes patients Tax:9606
752 1549-1557 Species denotes patients Tax:9606
753 1572-1580 Species denotes children Tax:9606
754 1696-1704 Species denotes patients Tax:9606
755 1938-1946 Species denotes patients Tax:9606
756 2011-2019 Species denotes children Tax:9606
757 2365-2373 Species denotes patients Tax:9606
758 2527-2535 Species denotes children Tax:9606
759 2578-2582 Species denotes boys Tax:9606
760 2592-2600 Species denotes children Tax:9606
761 2774-2782 Species denotes children Tax:9606
762 2880-2888 Species denotes patients Tax:9606
763 3003-3010 Species denotes patient Tax:9606
764 3158-3166 Species denotes children Tax:9606
765 3309-3319 Species denotes SARS-COV-2 Tax:2697049
766 3327-3335 Species denotes children Tax:9606
767 3349-3357 Species denotes patients Tax:9606
768 3510-3518 Species denotes patients Tax:9606
769 3592-3597 Species denotes Child Tax:9606
770 3634-3642 Species denotes patients Tax:9606
771 1296-1304 Chemical denotes steroids MESH:D013256
772 1627-1630 Chemical denotes KSS
773 2458-2461 Chemical denotes KSS
774 3125-3138 Chemical denotes triglycerides MESH:D014280
775 3219-3226 Chemical denotes aspirin MESH:D001241
776 183-191 Disease denotes COVID-19 MESH:C000657245
777 236-245 Disease denotes infection MESH:D007239
778 456-470 Disease denotes critically ill MESH:D016638
779 526-549 Disease denotes Kawasaki Shock Syndrome MESH:D009080
780 658-663 Disease denotes fever MESH:D005334
781 686-700 Disease denotes abdominal pain MESH:D015746
782 702-710 Disease denotes diarrhea MESH:D003967
783 712-721 Disease denotes skin rash MESH:D005076
784 817-828 Disease denotes dehydration MESH:D003681
785 862-872 Disease denotes arthralgia MESH:D018771
786 874-879 Disease denotes cough MESH:D003371
787 881-906 Disease denotes meningism, conjunctivitis MESH:D003231
788 1095-1106 Disease denotes myocarditis MESH:D009205
789 1156-1185 Disease denotes coronary artery abnormalities MESH:D003324
790 1214-1230 Disease denotes Kawasaki disease MESH:D009080
791 1457-1465 Disease denotes COVID-19 MESH:C000657245
792 1651-1659 Disease denotes COVID-19 MESH:C000657245
793 2122-2134 Disease denotes inflammation MESH:D007249
794 2156-2158 Disease denotes KD MESH:C537017
795 2645-2650 Disease denotes fever MESH:D005334
796 2652-2661 Disease denotes skin rash MESH:D005076
797 2663-2677 Disease denotes conjunctivitis MESH:D003231
798 2679-2696 Disease denotes peripheral oedema MESH:D004487
799 2712-2716 Disease denotes pain MESH:D010146
800 2718-2743 Disease denotes Gastrointestinal symptoms MESH:D012817
801 3029-3046 Disease denotes coronary aneurism MESH:D003324
802 3671-3691 Disease denotes SARS-CoV-2 infection MESH:C000657245
803 3916-3951 Disease denotes COVID-19 Hyperinflammatory Syndrome MESH:C000657245
804 4031-4051 Disease denotes multisystem syndrome MESH:D012791
805 4079-4099 Disease denotes SARS-CoV-2 infection MESH:C000657245