PMC:7289100 / 16045-17645
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T230 | 118-126 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T231 | 154-164 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T232 | 273-281 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T233 | 273-277 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T234 | 322-344 | Disease | denotes | pregnancy complication | http://purl.obolibrary.org/obo/MONDO_0024575 |
| T235 | 380-394 | Disease | denotes | HELLP syndrome | http://purl.obolibrary.org/obo/MONDO_0008585 |
| T236 | 485-493 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T237 | 629-637 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T238 | 649-667 | Disease | denotes | infectious disease | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T239 | 704-713 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T240 | 880-889 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T241 | 953-961 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T242 | 1032-1040 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T243 | 1351-1361 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T244 | 1376-1379 | Disease | denotes | APS | http://purl.obolibrary.org/obo/MONDO_0017278|http://purl.obolibrary.org/obo/MONDO_0007140 |
| T246 | 1390-1393 | Disease | denotes | APS | http://purl.obolibrary.org/obo/MONDO_0017278|http://purl.obolibrary.org/obo/MONDO_0007140 |
| T248 | 1423-1450 | Disease | denotes | systemic autoimmune disease | http://purl.obolibrary.org/obo/MONDO_0015939 |
| T249 | 1432-1450 | Disease | denotes | autoimmune disease | http://purl.obolibrary.org/obo/MONDO_0007179 |
| T250 | 1475-1485 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T136 | 419-420 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T137 | 641-642 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T138 | 893-894 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T139 | 1221-1222 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T140 | 1233-1240 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
| T141 | 1421-1422 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T80 | 1165-1178 | Chemical | denotes | anticoagulant | http://purl.obolibrary.org/obo/CHEBI_50249 |
| T81 | 1376-1379 | Chemical | denotes | APS | http://purl.obolibrary.org/obo/CHEBI_17709 |
| T82 | 1390-1393 | Chemical | denotes | APS | http://purl.obolibrary.org/obo/CHEBI_17709 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T122 | 44-47 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T123 | 220-232 | Phenotype | denotes | miscarriages | http://purl.obolibrary.org/obo/HP_0005268 |
| T124 | 367-370 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T125 | 529-532 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T126 | 718-721 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T127 | 841-844 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T128 | 989-992 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T129 | 1109-1112 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T130 | 1205-1208 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T131 | 1317-1320 | Phenotype | denotes | aPL | http://purl.obolibrary.org/obo/HP_0003613 |
| T132 | 1432-1450 | Phenotype | denotes | autoimmune disease | http://purl.obolibrary.org/obo/HP_0002960 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T103 | 0-180 | Sentence | denotes | The above considerations widely justify why aPL, detected with different assays, can be found in patients affected by COVID-19, sometimes associated with thrombosis but not always. |
| T104 | 181-421 | Sentence | denotes | To our knowledge, no increased rate of miscarriages or fetal loss have been reported during SARS-CoV-2 pandemic so far, although some severe pregnancy complication, like those linked to aPL, such as HELLP syndrome were occasionally seen (A. |
| T105 | 422-456 | Sentence | denotes | Lojacono, personal communication). |
| T106 | 457-628 | Sentence | denotes | Whether pregnant women with COVID-19 have an increased rate of positive aPL during pregnancy is not known yet nor it is defined their possible impact on pregnancy outcome. |
| T107 | 629-668 | Sentence | denotes | COVID-19 is a novel infectious disease. |
| T108 | 669-754 | Sentence | denotes | The true relationship between this infection and aPL need to be further investigated. |
| T109 | 755-962 | Sentence | denotes | However, according to the “second hit hypothesis” [60], the thrombogenic potential of aPL is magnified in the presence of an infection or a severe inflammatory state, which is often associated with COVID-19. |
| T110 | 963-1189 | Sentence | denotes | Therefore, the search for aPL may be considered in the management of COVID-19 patients with vascular manifestations, as the detection of positive aPL would allow of the indication for an early adequate anticoagulant treatment. |
| T111 | 1190-1380 | Sentence | denotes | In the case of aPL positivity, a follow-up testing after at least 12 weeks is warranted, in order to verify the persistence of aPL, which would suggest the post-infectious occurrence of APS. |
| T112 | 1381-1600 | Sentence | denotes | In fact, APS is currently considered as a systemic autoimmune disease which is not limited to thrombosis and pregnancy morbidity and deserves specific long-term management including anticoagulation and immunomodulation. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T279 | 118-126 | SP_7 | denotes | COVID-19 |
| T280 | 154-164 | GO:0007596 | denotes | thrombosis |
| T281 | 242-246 | GO:0016265 | denotes | loss |
| T282 | 273-283 | SP_7 | denotes | SARS-CoV-2 |
| T283 | 322-331 | GO:0007565 | denotes | pregnancy |
| T284 | 465-473 | GO:0007565 | denotes | pregnant |
| T285 | 485-493 | SP_7 | denotes | COVID-19 |
| T286 | 540-549 | GO:0007565 | denotes | pregnancy |
| T287 | 610-619 | GO:0007565 | denotes | pregnancy |
| T288 | 629-637 | SP_7 | denotes | COVID-19 |
| T289 | 815-827 | GO:0007596 | denotes | thrombogenic |
| T290 | 953-961 | SP_7 | denotes | COVID-19 |
| T291 | 1032-1040 | SP_7 | denotes | COVID-19 |
| T292 | 1165-1178 | GO:0050817 | denotes | anticoagulant |
| T293 | 1376-1379 | PR:000003015 | denotes | APS |
| T294 | 1390-1393 | PR:000003015 | denotes | APS |
| T295 | 1432-1442 | UBERON:0002405 | denotes | autoimmune |
| T296 | 1475-1485 | GO:0007596 | denotes | thrombosis |
| T297 | 1490-1499 | GO:0007565 | denotes | pregnancy |
| T298 | 1563-1578 | GO:0050817 | denotes | anticoagulation |
| T45853 | 118-126 | SP_7 | denotes | COVID-19 |
| T11768 | 154-164 | GO:0007596 | denotes | thrombosis |
| T60202 | 242-246 | GO:0016265 | denotes | loss |
| T76510 | 273-283 | SP_7 | denotes | SARS-CoV-2 |
| T26580 | 322-331 | GO:0007565 | denotes | pregnancy |
| T67168 | 465-473 | GO:0007565 | denotes | pregnant |
| T43542 | 485-493 | SP_7 | denotes | COVID-19 |
| T7181 | 540-549 | GO:0007565 | denotes | pregnancy |
| T25540 | 610-619 | GO:0007565 | denotes | pregnancy |
| T98519 | 629-637 | SP_7 | denotes | COVID-19 |
| T2783 | 815-827 | GO:0007596 | denotes | thrombogenic |
| T80124 | 953-961 | SP_7 | denotes | COVID-19 |
| T26341 | 1032-1040 | SP_7 | denotes | COVID-19 |
| T27610 | 1165-1178 | GO:0050817 | denotes | anticoagulant |
| T50089 | 1376-1379 | PR:000003015 | denotes | APS |
| T93273 | 1390-1393 | PR:000003015 | denotes | APS |
| T65115 | 1432-1442 | UBERON:0002405 | denotes | autoimmune |
| T44909 | 1475-1485 | GO:0007596 | denotes | thrombosis |
| T46209 | 1490-1499 | GO:0007565 | denotes | pregnancy |
| T49313 | 1563-1578 | GO:0050817 | denotes | anticoagulation |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 593 | 97-105 | Species | denotes | patients | Tax:9606 |
| 594 | 273-283 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 595 | 474-479 | Species | denotes | women | Tax:9606 |
| 596 | 1041-1049 | Species | denotes | patients | Tax:9606 |
| 597 | 44-47 | Disease | denotes | aPL | |
| 598 | 118-126 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 599 | 154-164 | Disease | denotes | thrombosis | MESH:D013927 |
| 600 | 367-370 | Disease | denotes | aPL | |
| 601 | 380-394 | Disease | denotes | HELLP syndrome | MESH:D017359 |
| 602 | 485-493 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 603 | 529-532 | Disease | denotes | aPL | |
| 604 | 629-637 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 605 | 649-667 | Disease | denotes | infectious disease | MESH:D003141 |
| 606 | 704-713 | Disease | denotes | infection | MESH:D007239 |
| 607 | 718-721 | Disease | denotes | aPL | |
| 608 | 841-844 | Disease | denotes | aPL | |
| 609 | 880-889 | Disease | denotes | infection | MESH:D007239 |
| 610 | 953-961 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 611 | 989-992 | Disease | denotes | aPL | |
| 612 | 1032-1040 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 613 | 1109-1112 | Disease | denotes | aPL | |
| 614 | 1205-1208 | Disease | denotes | aPL | |
| 615 | 1317-1320 | Disease | denotes | aPL | |
| 616 | 1376-1379 | Disease | denotes | APS | MESH:D016884 |
| 617 | 1390-1393 | Disease | denotes | APS | MESH:D016884 |
| 618 | 1432-1450 | Disease | denotes | autoimmune disease | MESH:D001327 |
| 619 | 1475-1485 | Disease | denotes | thrombosis | MESH:D013927 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32535093-16344491-4828873 | 806-808 | 16344491 | denotes | 60 |