PMC:7281546 / 54068-54900
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T329 | 181-188 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T330 | 524-531 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T331 | 653-664 | Body_part | denotes | peroxisomes | http://purl.org/sig/ont/fma/fma63845 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T119 | 301-304 | Disease | denotes | CBP | http://purl.obolibrary.org/obo/MONDO_0010565 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T506 | 311-312 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T507 | 342-343 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T508 | 369-379 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T509 | 572-573 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T510 | 697-713 | http://purl.obolibrary.org/obo/PR_000024990 | denotes | IFN and type III |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T92358 | 54-65 | Chemical | denotes | antagonists | http://purl.obolibrary.org/obo/CHEBI_48706 |
T77304 | 181-188 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T51413 | 524-531 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T11713 | 568-570 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T418 | 213-217 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | TBK1 |
T419 | 254-258 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | TBK1 |
T420 | 286-297 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
T421 | 345-360 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T422 | 401-422 | http://purl.obolibrary.org/obo/GO_0032606 | denotes | type I IFN production |
T423 | 476-497 | http://purl.obolibrary.org/obo/GO_0032606 | denotes | type I IFN production |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T413 | 0-66 | Sentence | denotes | Figure 3 The action model of PEDV interferons (IFNs) antagonists. |
T414 | 67-380 | Sentence | denotes | For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation. |
T415 | 381-498 | Sentence | denotes | PEDV nsp16 inhibits type I IFN production and nsp10 enhances the inhibitory effect of nsp16 on type I IFN production. |
T416 | 499-665 | Sentence | denotes | For type III IFN, PEDV N protein blocks the nuclear translocation of NF-κB; PEDV nsp1 blocks the nuclear translocation of IRF1 and reduces the amounts of peroxisomes. |
T417 | 666-750 | Sentence | denotes | PEDV nsp15 inhibits the type I IFN and type III IFN responses by unknown mechanisms. |
T418 | 751-832 | Sentence | denotes | PEDV nsp7 interacts with STAT1 and STAT2 to block nuclear translocation of ISGF3. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
2494 | 88-92 | Gene | denotes | PLP2 | Gene:5355 |
2495 | 131-136 | Gene | denotes | RIG-I | Gene:23586 |
2496 | 143-147 | Gene | denotes | nsp5 | Gene:92521 |
2497 | 168-172 | Gene | denotes | NEMO | Gene:8517 |
2498 | 213-217 | Gene | denotes | TBK1 | Gene:29110 |
2499 | 254-258 | Gene | denotes | TBK1 | Gene:29110 |
2500 | 263-267 | Gene | denotes | IRF3 | Gene:3661 |
2501 | 274-278 | Gene | denotes | nsp1 | Gene:10045 |
2502 | 301-304 | Gene | denotes | CBP | Gene:1387 |
2503 | 309-313 | Gene | denotes | IκBα | Gene:4792 |
2504 | 340-344 | Gene | denotes | IκBα | Gene:4792 |
2505 | 365-368 | Gene | denotes | p65 | Gene:5970 |
2506 | 568-573 | Gene | denotes | NF-κB | Gene:4790 |
2507 | 580-584 | Gene | denotes | nsp1 | Gene:10045 |
2508 | 621-625 | Gene | denotes | IRF1 | Gene:3659 |
2509 | 776-781 | Gene | denotes | STAT1 | Gene:6772 |
2510 | 786-791 | Gene | denotes | STAT2 | Gene:6773 |
2511 | 826-831 | Gene | denotes | ISGF3 | Gene:10379 |
2512 | 30-34 | Species | denotes | PEDV | Tax:28295 |
2513 | 83-87 | Species | denotes | PEDV | Tax:28295 |
2514 | 138-142 | Species | denotes | PEDV | Tax:28295 |
2515 | 174-178 | Species | denotes | PEDV | Tax:28295 |
2516 | 269-273 | Species | denotes | PEDV | Tax:28295 |
2517 | 381-385 | Species | denotes | PEDV | Tax:28295 |
2518 | 575-579 | Species | denotes | PEDV | Tax:28295 |
2519 | 666-670 | Species | denotes | PEDV | Tax:28295 |
2520 | 751-755 | Species | denotes | PEDV | Tax:28295 |
2521 | 512-515 | Gene | denotes | IFN | Gene:3439 |