PMC:7281546 / 32958-33316 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T206","span":{"begin":177,"end":186},"obj":"Body_part"}],"attributes":[{"id":"A206","pred":"fma_id","subj":"T206","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T81","span":{"begin":219,"end":234},"obj":"Disease"},{"id":"T82","span":{"begin":225,"end":234},"obj":"Disease"}],"attributes":[{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A82","pred":"mondo_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T290","span":{"begin":16,"end":21},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T291","span":{"begin":103,"end":112},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T292","span":{"begin":117,"end":118},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T293","span":{"begin":246,"end":249},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T294","span":{"begin":287,"end":288},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T295","span":{"begin":289,"end":297},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T297","span":{"begin":12,"end":15},"obj":"Chemical"},{"id":"T298","span":{"begin":72,"end":75},"obj":"Chemical"},{"id":"T299","span":{"begin":94,"end":101},"obj":"Chemical"},{"id":"T300","span":{"begin":113,"end":115},"obj":"Chemical"},{"id":"T303","span":{"begin":283,"end":285},"obj":"Chemical"}],"attributes":[{"id":"A297","pred":"chebi_id","subj":"T297","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A298","pred":"chebi_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"},{"id":"A300","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A301","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A302","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A304","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A305","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T201","span":{"begin":65,"end":86},"obj":"http://purl.obolibrary.org/obo/GO_0032606"},{"id":"T202","span":{"begin":219,"end":234},"obj":"http://purl.obolibrary.org/obo/GO_0016032"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}

{"project":"LitCovid-sentences","denotations":[{"id":"T234","span":{"begin":37,"end":102},"obj":"Sentence"},{"id":"T235","span":{"begin":103,"end":235},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}

{"project":"2_test","denotations":[{"id":"32403318-17483521-82827423","span":{"begin":23,"end":26},"obj":"17483521"},{"id":"32403318-9566918-82827424","span":{"begin":27,"end":30},"obj":"9566918"},{"id":"32403318-17574024-82827425","span":{"begin":31,"end":34},"obj":"17574024"},{"id":"32403318-28715653-82827426","span":{"begin":299,"end":301},"obj":"28715653"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1085","span":{"begin":53,"end":57},"obj":"Gene"},{"id":"1086","span":{"begin":113,"end":118},"obj":"Gene"},{"id":"1087","span":{"begin":241,"end":245},"obj":"Gene"},{"id":"1088","span":{"begin":283,"end":288},"obj":"Gene"},{"id":"1105","span":{"begin":48,"end":52},"obj":"Species"},{"id":"1106","span":{"begin":236,"end":240},"obj":"Species"},{"id":"1112","span":{"begin":12,"end":15},"obj":"Gene"},{"id":"1115","span":{"begin":219,"end":234},"obj":"Disease"}],"attributes":[{"id":"A1085","pred":"tao:has_database_id","subj":"1085","obj":"Gene:10045"},{"id":"A1086","pred":"tao:has_database_id","subj":"1086","obj":"Gene:4790"},{"id":"A1087","pred":"tao:has_database_id","subj":"1087","obj":"Gene:10045"},{"id":"A1088","pred":"tao:has_database_id","subj":"1088","obj":"Gene:4790"},{"id":"A1105","pred":"tao:has_database_id","subj":"1105","obj":"Tax:28295"},{"id":"A1106","pred":"tao:has_database_id","subj":"1106","obj":"Tax:28295"},{"id":"A1112","pred":"tao:has_database_id","subj":"1112","obj":"Gene:3439"},{"id":"A1115","pred":"tao:has_database_id","subj":"1115","obj":"MESH:D001102"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"n of type I IFN genes [184,185,186]. Therefore, PEDV nsp1 blocks type I IFN production in the nucleus. Activated NF-κB induces the production of type I IFNs and proinflammatory cytokines and is important for inhibiting viral infection. PEDV nsp1 has been shown to interfere with the NF-κB activity [78] and is the most potent suppressor of proinflammatory cy"}