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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T63","span":{"begin":271,"end":274},"obj":"Body_part"},{"id":"T64","span":{"begin":285,"end":288},"obj":"Body_part"},{"id":"T65","span":{"begin":362,"end":369},"obj":"Body_part"},{"id":"T66","span":{"begin":485,"end":493},"obj":"Body_part"}],"attributes":[{"id":"A63","pred":"fma_id","subj":"T63","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A64","pred":"fma_id","subj":"T64","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A65","pred":"fma_id","subj":"T65","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A66","pred":"fma_id","subj":"T66","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"4. Conclusions\nA molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2). The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol. The docking energies were relatively weak, however, and are unlikely to interact with the virus targets. However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"953","span":{"begin":141,"end":145},"obj":"Gene"},{"id":"954","span":{"begin":312,"end":316},"obj":"Gene"},{"id":"955","span":{"begin":356,"end":361},"obj":"Gene"},{"id":"956","span":{"begin":397,"end":426},"obj":"Gene"},{"id":"957","span":{"begin":428,"end":433},"obj":"Gene"},{"id":"958","span":{"begin":104,"end":114},"obj":"Species"},{"id":"959","span":{"begin":130,"end":140},"obj":"Species"},{"id":"960","span":{"begin":148,"end":158},"obj":"Species"},{"id":"961","span":{"begin":178,"end":188},"obj":"Species"},{"id":"962","span":{"begin":204,"end":214},"obj":"Species"},{"id":"963","span":{"begin":242,"end":252},"obj":"Species"},{"id":"964","span":{"begin":260,"end":270},"obj":"Species"},{"id":"965","span":{"begin":301,"end":311},"obj":"Species"},{"id":"966","span":{"begin":345,"end":355},"obj":"Species"},{"id":"967","span":{"begin":371,"end":381},"obj":"Species"},{"id":"968","span":{"begin":391,"end":396},"obj":"Species"},{"id":"969","span":{"begin":469,"end":477},"obj":"Species"},{"id":"970","span":{"begin":502,"end":506},"obj":"Species"},{"id":"971","span":{"begin":518,"end":533},"obj":"Chemical"},{"id":"972","span":{"begin":539,"end":553},"obj":"Chemical"},{"id":"973","span":{"begin":669,"end":682},"obj":"Chemical"},{"id":"974","span":{"begin":719,"end":733},"obj":"Chemical"},{"id":"975","span":{"begin":808,"end":816},"obj":"Disease"}],"attributes":[{"id":"A953","pred":"tao:has_database_id","subj":"953","obj":"Gene:8673700"},{"id":"A954","pred":"tao:has_database_id","subj":"954","obj":"Gene:43740578"},{"id":"A955","pred":"tao:has_database_id","subj":"955","obj":"Gene:43740568"},{"id":"A956","pred":"tao:has_database_id","subj":"956","obj":"Gene:1636"},{"id":"A957","pred":"tao:has_database_id","subj":"957","obj":"Gene:59272"},{"id":"A958","pred":"tao:has_database_id","subj":"958","obj":"Tax:2697049"},{"id":"A959","pred":"tao:has_database_id","subj":"959","obj":"Tax:2697049"},{"id":"A960","pred":"tao:has_database_id","subj":"960","obj":"Tax:2697049"},{"id":"A961","pred":"tao:has_database_id","subj":"961","obj":"Tax:2697049"},{"id":"A962","pred":"tao:has_database_id","subj":"962","obj":"Tax:2697049"},{"id":"A963","pred":"tao:has_database_id","subj":"963","obj":"Tax:2697049"},{"id":"A964","pred":"tao:has_database_id","subj":"964","obj":"Tax:2697049"},{"id":"A965","pred":"tao:has_database_id","subj":"965","obj":"Tax:2697049"},{"id":"A966","pred":"tao:has_database_id","subj":"966","obj":"Tax:2697049"},{"id":"A967","pred":"tao:has_database_id","subj":"967","obj":"Tax:2697049"},{"id":"A968","pred":"tao:has_database_id","subj":"968","obj":"Tax:9606"},{"id":"A969","pred":"tao:has_database_id","subj":"969","obj":"Tax:694009"},{"id":"A970","pred":"tao:has_database_id","subj":"970","obj":"Tax:114629"},{"id":"A973","pred":"tao:has_database_id","subj":"973","obj":"MESH:D009822"},{"id":"A974","pred":"tao:has_database_id","subj":"974","obj":"MESH:D009822"},{"id":"A975","pred":"tao:has_database_id","subj":"975","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"4. Conclusions\nA molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2). The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol. The docking energies were relatively weak, however, and are unlikely to interact with the virus targets. However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T128","span":{"begin":104,"end":112},"obj":"Disease"},{"id":"T129","span":{"begin":130,"end":138},"obj":"Disease"},{"id":"T130","span":{"begin":148,"end":156},"obj":"Disease"},{"id":"T131","span":{"begin":178,"end":186},"obj":"Disease"},{"id":"T132","span":{"begin":204,"end":212},"obj":"Disease"},{"id":"T133","span":{"begin":242,"end":250},"obj":"Disease"},{"id":"T134","span":{"begin":260,"end":268},"obj":"Disease"},{"id":"T135","span":{"begin":301,"end":309},"obj":"Disease"},{"id":"T136","span":{"begin":345,"end":353},"obj":"Disease"},{"id":"T137","span":{"begin":371,"end":379},"obj":"Disease"},{"id":"T138","span":{"begin":469,"end":477},"obj":"Disease"},{"id":"T139","span":{"begin":808,"end":816},"obj":"Disease"}],"attributes":[{"id":"A128","pred":"mondo_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A129","pred":"mondo_id","subj":"T129","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A130","pred":"mondo_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A131","pred":"mondo_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A132","pred":"mondo_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A133","pred":"mondo_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A134","pred":"mondo_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A135","pred":"mondo_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A136","pred":"mondo_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A137","pred":"mondo_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A138","pred":"mondo_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A139","pred":"mondo_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"4. Conclusions\nA molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2). The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol. The docking energies were relatively weak, however, and are unlikely to interact with the virus targets. However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T166","span":{"begin":15,"end":16},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T167","span":{"begin":382,"end":384},"obj":"http://purl.obolibrary.org/obo/CLO_0008882"},{"id":"T168","span":{"begin":391,"end":396},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T169","span":{"begin":645,"end":650},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"4. Conclusions\nA molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2). The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol. The docking energies were relatively weak, however, and are unlikely to interact with the virus targets. However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms."}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T381","span":{"begin":70,"end":94},"obj":"Chemical"},{"id":"T382","span":{"begin":70,"end":83},"obj":"Chemical"},{"id":"T383","span":{"begin":215,"end":218},"obj":"Chemical"},{"id":"T386","span":{"begin":219,"end":225},"obj":"Chemical"},{"id":"T388","span":{"begin":362,"end":369},"obj":"Chemical"},{"id":"T389","span":{"begin":397,"end":408},"obj":"Chemical"},{"id":"T390","span":{"begin":453,"end":460},"obj":"Chemical"},{"id":"T391","span":{"begin":485,"end":493},"obj":"Chemical"},{"id":"T392","span":{"begin":507,"end":516},"obj":"Chemical"},{"id":"T393","span":{"begin":524,"end":533},"obj":"Chemical"},{"id":"T394","span":{"begin":539,"end":553},"obj":"Chemical"},{"id":"T395","span":{"begin":545,"end":553},"obj":"Chemical"},{"id":"T396","span":{"begin":669,"end":693},"obj":"Chemical"},{"id":"T397","span":{"begin":669,"end":682},"obj":"Chemical"},{"id":"T398","span":{"begin":719,"end":733},"obj":"Chemical"},{"id":"T399","span":{"begin":755,"end":771},"obj":"Chemical"}],"attributes":[{"id":"A381","pred":"chebi_id","subj":"T381","obj":"http://purl.obolibrary.org/obo/CHEBI_27311"},{"id":"A382","pred":"chebi_id","subj":"T382","obj":"http://purl.obolibrary.org/obo/CHEBI_83630"},{"id":"A383","pred":"chebi_id","subj":"T383","obj":"http://purl.obolibrary.org/obo/CHEBI_16761"},{"id":"A384","pred":"chebi_id","subj":"T383","obj":"http://purl.obolibrary.org/obo/CHEBI_456216"},{"id":"A385","pred":"chebi_id","subj":"T383","obj":"http://purl.obolibrary.org/obo/CHEBI_73342"},{"id":"A386","pred":"chebi_id","subj":"T386","obj":"http://purl.obolibrary.org/obo/CHEBI_33942"},{"id":"A387","pred":"chebi_id","subj":"T386","obj":"http://purl.obolibrary.org/obo/CHEBI_47013"},{"id":"A388","pred":"chebi_id","subj":"T388","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A389","pred":"chebi_id","subj":"T389","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A390","pred":"chebi_id","subj":"T390","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A391","pred":"chebi_id","subj":"T391","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A392","pred":"chebi_id","subj":"T392","obj":"http://purl.obolibrary.org/obo/CHEBI_39237"},{"id":"A393","pred":"chebi_id","subj":"T393","obj":"http://purl.obolibrary.org/obo/CHEBI_39237"},{"id":"A394","pred":"chebi_id","subj":"T394","obj":"http://purl.obolibrary.org/obo/CHEBI_16619"},{"id":"A395","pred":"chebi_id","subj":"T395","obj":"http://purl.obolibrary.org/obo/CHEBI_28600"},{"id":"A396","pred":"chebi_id","subj":"T396","obj":"http://purl.obolibrary.org/obo/CHEBI_27311"},{"id":"A397","pred":"chebi_id","subj":"T397","obj":"http://purl.obolibrary.org/obo/CHEBI_83630"},{"id":"A398","pred":"chebi_id","subj":"T398","obj":"http://purl.obolibrary.org/obo/CHEBI_83630"},{"id":"A399","pred":"chebi_id","subj":"T399","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"4. Conclusions\nA molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2). The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol. The docking energies were relatively weak, however, and are unlikely to interact with the virus targets. However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms."}

    LitCovid-PD-GO-BP

    {"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T17","span":{"begin":229,"end":240},"obj":"http://purl.obolibrary.org/obo/GO_0016791"}],"text":"4. Conclusions\nA molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2). The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol. The docking energies were relatively weak, however, and are unlikely to interact with the virus targets. However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T175","span":{"begin":0,"end":2},"obj":"Sentence"},{"id":"T176","span":{"begin":3,"end":14},"obj":"Sentence"},{"id":"T177","span":{"begin":15,"end":435},"obj":"Sentence"},{"id":"T178","span":{"begin":436,"end":554},"obj":"Sentence"},{"id":"T179","span":{"begin":555,"end":659},"obj":"Sentence"},{"id":"T180","span":{"begin":660,"end":826},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"4. Conclusions\nA molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2). The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol. The docking energies were relatively weak, however, and are unlikely to interact with the virus targets. However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms."}