PMC:7279430 / 24288-25114 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	fma_id
T63	271-274	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T64	285-288	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T65	362-369	Body_part	denotes	protein	http://purl.org/sig/ont/fma/fma67257
T66	485-493	Body_part	denotes	proteins	http://purl.org/sig/ont/fma/fma67257

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
953	141-145	Gene	denotes	Mpro	Gene:8673700
954	312-316	Gene	denotes	RdRp	Gene:43740578
955	356-361	Gene	denotes	spike	Gene:43740568
956	397-426	Gene	denotes	angiotensin-converting enzyme	Gene:1636
957	428-433	Gene	denotes	hACE2	Gene:59272
958	104-114	Species	denotes	SARS-CoV-2	Tax:2697049
959	130-140	Species	denotes	SARS-CoV-2	Tax:2697049
960	148-158	Species	denotes	SARS-CoV-2	Tax:2697049
961	178-188	Species	denotes	SARS-CoV-2	Tax:2697049
962	204-214	Species	denotes	SARS-CoV-2	Tax:2697049
963	242-252	Species	denotes	SARS-CoV-2	Tax:2697049
964	260-270	Species	denotes	SARS-CoV-2	Tax:2697049
965	301-311	Species	denotes	SARS-CoV-2	Tax:2697049
966	345-355	Species	denotes	SARS-CoV-2	Tax:2697049
967	371-381	Species	denotes	SARS-CoV-2	Tax:2697049
968	391-396	Species	denotes	human	Tax:9606
969	469-477	Species	denotes	SARS-CoV	Tax:694009
970	502-506	Species	denotes	E)-α	Tax:114629
971	518-533	Chemical	denotes	(E)-β-farnesene
972	539-553	Chemical	denotes	(E,E)-farnesol
973	669-682	Chemical	denotes	essential oil	MESH:D009822
974	719-733	Chemical	denotes	essential oils	MESH:D009822
975	808-816	Disease	denotes	COVID-19	MESH:C000657245

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T128	104-112	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T129	130-138	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T130	148-156	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T131	178-186	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T132	204-212	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T133	242-250	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T134	260-268	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T135	301-309	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T136	345-353	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T137	371-379	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T138	469-477	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T139	808-816	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096

Id	Subject	Object	Predicate	Lexical cue
T166	15-16	http://purl.obolibrary.org/obo/CLO_0001020	denotes	A
T167	382-384	http://purl.obolibrary.org/obo/CLO_0008882	denotes	rS
T168	391-396	http://purl.obolibrary.org/obo/NCBITaxon_9606	denotes	human
T169	645-650	http://purl.obolibrary.org/obo/NCBITaxon_10239	denotes	virus

Id	Subject	Object	Predicate	Lexical cue	chebi_id
T381	70-94	Chemical	denotes	essential oil components	http://purl.obolibrary.org/obo/CHEBI_27311
T382	70-83	Chemical	denotes	essential oil	http://purl.obolibrary.org/obo/CHEBI_83630
T383	215-218	Chemical	denotes	ADP	http://purl.obolibrary.org/obo/CHEBI_16761\|http://purl.obolibrary.org/obo/CHEBI_456216\|http://purl.obolibrary.org/obo/CHEBI_73342
T386	219-225	Chemical	denotes	ribose	http://purl.obolibrary.org/obo/CHEBI_33942\|http://purl.obolibrary.org/obo/CHEBI_47013
T388	362-369	Chemical	denotes	protein	http://purl.obolibrary.org/obo/CHEBI_36080
T389	397-408	Chemical	denotes	angiotensin	http://purl.obolibrary.org/obo/CHEBI_48433
T390	453-460	Chemical	denotes	ligands	http://purl.obolibrary.org/obo/CHEBI_52214
T391	485-493	Chemical	denotes	proteins	http://purl.obolibrary.org/obo/CHEBI_36080
T392	507-516	Chemical	denotes	farnesene	http://purl.obolibrary.org/obo/CHEBI_39237
T393	524-533	Chemical	denotes	farnesene	http://purl.obolibrary.org/obo/CHEBI_39237
T394	539-553	Chemical	denotes	(E,E)-farnesol	http://purl.obolibrary.org/obo/CHEBI_16619
T395	545-553	Chemical	denotes	farnesol	http://purl.obolibrary.org/obo/CHEBI_28600
T396	669-693	Chemical	denotes	essential oil components	http://purl.obolibrary.org/obo/CHEBI_27311
T397	669-682	Chemical	denotes	essential oil	http://purl.obolibrary.org/obo/CHEBI_83630
T398	719-733	Chemical	denotes	essential oils	http://purl.obolibrary.org/obo/CHEBI_83630
T399	755-771	Chemical	denotes	antiviral agents	http://purl.obolibrary.org/obo/CHEBI_22587

Id	Subject	Object	Predicate	Lexical cue
T17	229-240	http://purl.obolibrary.org/obo/GO_0016791	denotes	phosphatase

Id	Subject	Object	Predicate	Lexical cue
T175	0-2	Sentence	denotes	4.
T176	3-14	Sentence	denotes	Conclusions
T177	15-435	Sentence	denotes	A molecular docking analysis was carried out using 171 essential oil components with the SARS-CoV-2 main protease (SARS-CoV-2 Mpro), SARS-CoV-2 endoribonucleoase (SARS-CoV-2 Nsp15/NendoU), SARS-CoV-2 ADP-ribose-1″-phosphatase (SARS-CoV-2 ADRP), SARS-CoV-2 RNA-dependent RNA polymerase (SARS-CoV-2 RdRp), the binding domain of the SARS-CoV-2 spike protein (SARS-CoV-2 rS), and human angiotensin-converting enzyme (hACE2).
T178	436-554	Sentence	denotes	The best docking ligands for the SARS-CoV target proteins were (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol.
T179	555-659	Sentence	denotes	The docking energies were relatively weak, however, and are unlikely to interact with the virus targets.
T180	660-826	Sentence	denotes	However, essential oil components may act synergistically, essential oils may potentiate other antiviral agents, or they may provide some relief of COVID-19 symptoms.