PMC:7274950 / 5909-6712 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T102","span":{"begin":134,"end":145},"obj":"UBERON:0001004"},{"id":"T103","span":{"begin":218,"end":222},"obj":"UBERON:0002048"},{"id":"T104","span":{"begin":287,"end":293},"obj":"UBERON:0001005"},{"id":"T105","span":{"begin":400,"end":404},"obj":"UBERON:0002048"},{"id":"T106","span":{"begin":489,"end":493},"obj":"UBERON:0002048"},{"id":"T107","span":{"begin":660,"end":669},"obj":"UBERON:0002048"},{"id":"T40276","span":{"begin":134,"end":145},"obj":"UBERON:0001004"},{"id":"T94550","span":{"begin":218,"end":222},"obj":"UBERON:0002048"},{"id":"T82243","span":{"begin":287,"end":293},"obj":"UBERON:0001005"},{"id":"T71068","span":{"begin":400,"end":404},"obj":"UBERON:0002048"},{"id":"T44732","span":{"begin":489,"end":493},"obj":"UBERON:0002048"},{"id":"T99838","span":{"begin":660,"end":669},"obj":"UBERON:0002048"}],"text":"Odler et al. [17] published the evaluation of 7 Fabry patients (40.2 ± 5.6 years) before and after ERT. At baseline, all patients had respiratory symptoms; however, these symptoms were usually mild. The most prominent lung function changes were registered in parameters reflecting small airway involvement, including significant decrease in FEF25 – 75, increase in residual volume (RV) and RV/ total lung capacity ratio. Furthermore, a review by Franzen et al. [18] found that obstructive lung disease was up to 10 times more frequent in patients with Fabry disease compared to the general population. The same author later reported the long-term follow-up of pulmonary function in 95 patients (41% males). The overall prevalence of bronchial obstruction was 46%, and FEV1 decreased 29 ml per year [19]."}

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{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T41","span":{"begin":477,"end":501},"obj":"Disease"},{"id":"T42","span":{"begin":489,"end":501},"obj":"Disease"},{"id":"T43","span":{"begin":552,"end":565},"obj":"Disease"}],"attributes":[{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0002267"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0005275"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0010526"}],"text":"Odler et al. [17] published the evaluation of 7 Fabry patients (40.2 ± 5.6 years) before and after ERT. At baseline, all patients had respiratory symptoms; however, these symptoms were usually mild. The most prominent lung function changes were registered in parameters reflecting small airway involvement, including significant decrease in FEF25 – 75, increase in residual volume (RV) and RV/ total lung capacity ratio. Furthermore, a review by Franzen et al. [18] found that obstructive lung disease was up to 10 times more frequent in patients with Fabry disease compared to the general population. The same author later reported the long-term follow-up of pulmonary function in 95 patients (41% males). The overall prevalence of bronchial obstruction was 46%, and FEV1 decreased 29 ml per year [19]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T77","span":{"begin":218,"end":222},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T78","span":{"begin":218,"end":222},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T79","span":{"begin":287,"end":293},"obj":"http://purl.obolibrary.org/obo/UBERON_0001005"},{"id":"T80","span":{"begin":400,"end":404},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T81","span":{"begin":400,"end":404},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T82","span":{"begin":434,"end":435},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T83","span":{"begin":462,"end":464},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T84","span":{"begin":489,"end":493},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T85","span":{"begin":489,"end":493},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T86","span":{"begin":695,"end":697},"obj":"http://purl.obolibrary.org/obo/CLO_0053794"},{"id":"T87","span":{"begin":699,"end":704},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T88","span":{"begin":699,"end":704},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"}],"text":"Odler et al. [17] published the evaluation of 7 Fabry patients (40.2 ± 5.6 years) before and after ERT. At baseline, all patients had respiratory symptoms; however, these symptoms were usually mild. The most prominent lung function changes were registered in parameters reflecting small airway involvement, including significant decrease in FEF25 – 75, increase in residual volume (RV) and RV/ total lung capacity ratio. Furthermore, a review by Franzen et al. [18] found that obstructive lung disease was up to 10 times more frequent in patients with Fabry disease compared to the general population. The same author later reported the long-term follow-up of pulmonary function in 95 patients (41% males). The overall prevalence of bronchial obstruction was 46%, and FEV1 decreased 29 ml per year [19]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T19","span":{"begin":382,"end":384},"obj":"Chemical"},{"id":"T20","span":{"begin":390,"end":392},"obj":"Chemical"}],"attributes":[{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_73823"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_73823"}],"text":"Odler et al. [17] published the evaluation of 7 Fabry patients (40.2 ± 5.6 years) before and after ERT. At baseline, all patients had respiratory symptoms; however, these symptoms were usually mild. The most prominent lung function changes were registered in parameters reflecting small airway involvement, including significant decrease in FEF25 – 75, increase in residual volume (RV) and RV/ total lung capacity ratio. Furthermore, a review by Franzen et al. [18] found that obstructive lung disease was up to 10 times more frequent in patients with Fabry disease compared to the general population. The same author later reported the long-term follow-up of pulmonary function in 95 patients (41% males). The overall prevalence of bronchial obstruction was 46%, and FEV1 decreased 29 ml per year [19]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T31","span":{"begin":477,"end":501},"obj":"Phenotype"}],"attributes":[{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0006536"}],"text":"Odler et al. [17] published the evaluation of 7 Fabry patients (40.2 ± 5.6 years) before and after ERT. At baseline, all patients had respiratory symptoms; however, these symptoms were usually mild. The most prominent lung function changes were registered in parameters reflecting small airway involvement, including significant decrease in FEF25 – 75, increase in residual volume (RV) and RV/ total lung capacity ratio. Furthermore, a review by Franzen et al. [18] found that obstructive lung disease was up to 10 times more frequent in patients with Fabry disease compared to the general population. The same author later reported the long-term follow-up of pulmonary function in 95 patients (41% males). The overall prevalence of bronchial obstruction was 46%, and FEV1 decreased 29 ml per year [19]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T43","span":{"begin":0,"end":103},"obj":"Sentence"},{"id":"T44","span":{"begin":104,"end":198},"obj":"Sentence"},{"id":"T45","span":{"begin":199,"end":420},"obj":"Sentence"},{"id":"T46","span":{"begin":421,"end":601},"obj":"Sentence"},{"id":"T47","span":{"begin":602,"end":706},"obj":"Sentence"},{"id":"T48","span":{"begin":707,"end":803},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Odler et al. [17] published the evaluation of 7 Fabry patients (40.2 ± 5.6 years) before and after ERT. At baseline, all patients had respiratory symptoms; however, these symptoms were usually mild. The most prominent lung function changes were registered in parameters reflecting small airway involvement, including significant decrease in FEF25 – 75, increase in residual volume (RV) and RV/ total lung capacity ratio. Furthermore, a review by Franzen et al. [18] found that obstructive lung disease was up to 10 times more frequent in patients with Fabry disease compared to the general population. The same author later reported the long-term follow-up of pulmonary function in 95 patients (41% males). The overall prevalence of bronchial obstruction was 46%, and FEV1 decreased 29 ml per year [19]."}