PMC:7272971 / 9821-10488 JSONTXT

Annnotations TAB JSON ListView MergeView

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"329","span":{"begin":107,"end":111},"obj":"Gene"},{"id":"330","span":{"begin":256,"end":263},"obj":"Gene"},{"id":"331","span":{"begin":272,"end":277},"obj":"Gene"},{"id":"332","span":{"begin":301,"end":305},"obj":"Gene"},{"id":"333","span":{"begin":335,"end":340},"obj":"Gene"},{"id":"334","span":{"begin":0,"end":13},"obj":"Species"},{"id":"335","span":{"begin":33,"end":38},"obj":"Species"},{"id":"336","span":{"begin":100,"end":105},"obj":"Species"},{"id":"337","span":{"begin":430,"end":438},"obj":"Species"},{"id":"338","span":{"begin":39,"end":58},"obj":"Disease"},{"id":"339","span":{"begin":150,"end":159},"obj":"Disease"},{"id":"340","span":{"begin":205,"end":223},"obj":"Disease"},{"id":"341","span":{"begin":374,"end":391},"obj":"Disease"},{"id":"342","span":{"begin":483,"end":492},"obj":"Disease"},{"id":"343","span":{"begin":600,"end":621},"obj":"Disease"}],"attributes":[{"id":"A329","pred":"tao:has_database_id","subj":"329","obj":"Gene:59272"},{"id":"A330","pred":"tao:has_database_id","subj":"330","obj":"Gene:7113"},{"id":"A331","pred":"tao:has_database_id","subj":"331","obj":"Gene:43740568"},{"id":"A332","pred":"tao:has_database_id","subj":"332","obj":"Gene:59272"},{"id":"A333","pred":"tao:has_database_id","subj":"333","obj":"Gene:30835"},{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"Tax:11118"},{"id":"A335","pred":"tao:has_database_id","subj":"335","obj":"Tax:9606"},{"id":"A336","pred":"tao:has_database_id","subj":"336","obj":"Tax:2697049"},{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"Tax:1335626"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"MESH:C000657245"},{"id":"A339","pred":"tao:has_database_id","subj":"339","obj":"MESH:D007239"},{"id":"A340","pred":"tao:has_database_id","subj":"340","obj":"MESH:D003316"},{"id":"A341","pred":"tao:has_database_id","subj":"341","obj":"MESH:D003316"},{"id":"A342","pred":"tao:has_database_id","subj":"342","obj":"MESH:D007239"},{"id":"A343","pred":"tao:has_database_id","subj":"343","obj":"MESH:C563620"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Coronaviruses Receptor Role in human CoV disease Ocular surface (cell types) Lung\nSARS‐CoV\nSARS‐CoV‐2 ACE2 Host cell receptor and essential for infection + (conjunctival epithelium and fibroblasts; corneal epithelium) 31 + (airway epithelia)32, 33\nTMPRSS2 Primes spike protein for binding to ACE2 – + (airway epithelium) 34\nCD209 Cell‐to‐cell viral transfer + (corneal dendritic cells) 35 + (alveola macrophages) 36\nMERS‐CoV CD26 Host cell receptor and essential for infection +/− (conjunctival vascular endothelium) 37 + (lung epithelia and endothelia) 38\nCD66e Co‐receptor +/− (palpebral conjunctiva) 39 + (bronchial and alveolar epithelium) 32"}

    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T70","span":{"begin":68,"end":72},"obj":"Body_part"},{"id":"T71","span":{"begin":81,"end":85},"obj":"Body_part"},{"id":"T72","span":{"begin":118,"end":122},"obj":"Body_part"},{"id":"T73","span":{"begin":177,"end":187},"obj":"Body_part"},{"id":"T74","span":{"begin":192,"end":203},"obj":"Body_part"},{"id":"T75","span":{"begin":205,"end":223},"obj":"Body_part"},{"id":"T76","span":{"begin":213,"end":223},"obj":"Body_part"},{"id":"T77","span":{"begin":239,"end":248},"obj":"Body_part"},{"id":"T78","span":{"begin":278,"end":285},"obj":"Body_part"},{"id":"T79","span":{"begin":320,"end":330},"obj":"Body_part"},{"id":"T80","span":{"begin":342,"end":346},"obj":"Body_part"},{"id":"T81","span":{"begin":350,"end":354},"obj":"Body_part"},{"id":"T82","span":{"begin":382,"end":397},"obj":"Body_part"},{"id":"T83","span":{"begin":392,"end":397},"obj":"Body_part"},{"id":"T84","span":{"begin":414,"end":425},"obj":"Body_part"},{"id":"T85","span":{"begin":451,"end":455},"obj":"Body_part"},{"id":"T86","span":{"begin":521,"end":532},"obj":"Body_part"},{"id":"T87","span":{"begin":541,"end":545},"obj":"Body_part"},{"id":"T88","span":{"begin":546,"end":555},"obj":"Body_part"},{"id":"T89","span":{"begin":600,"end":621},"obj":"Body_part"},{"id":"T90","span":{"begin":644,"end":663},"obj":"Body_part"},{"id":"T91","span":{"begin":653,"end":663},"obj":"Body_part"}],"attributes":[{"id":"A70","pred":"fma_id","subj":"T70","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A71","pred":"fma_id","subj":"T71","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A72","pred":"fma_id","subj":"T72","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A73","pred":"fma_id","subj":"T73","obj":"http://purl.org/sig/ont/fma/fma9639"},{"id":"A74","pred":"fma_id","subj":"T74","obj":"http://purl.org/sig/ont/fma/fma63877"},{"id":"A75","pred":"fma_id","subj":"T75","obj":"http://purl.org/sig/ont/fma/fma58263"},{"id":"A76","pred":"fma_id","subj":"T76","obj":"http://purl.org/sig/ont/fma/fma9639"},{"id":"A77","pred":"fma_id","subj":"T77","obj":"http://purl.org/sig/ont/fma/fma9639"},{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A79","pred":"fma_id","subj":"T79","obj":"http://purl.org/sig/ont/fma/fma9639"},{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A81","pred":"fma_id","subj":"T81","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A82","pred":"fma_id","subj":"T82","obj":"http://purl.org/sig/ont/fma/fma273565"},{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A84","pred":"fma_id","subj":"T84","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A85","pred":"fma_id","subj":"T85","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A86","pred":"fma_id","subj":"T86","obj":"http://purl.org/sig/ont/fma/fma63916"},{"id":"A87","pred":"fma_id","subj":"T87","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A88","pred":"fma_id","subj":"T88","obj":"http://purl.org/sig/ont/fma/fma9639"},{"id":"A89","pred":"fma_id","subj":"T89","obj":"http://purl.org/sig/ont/fma/fma59025"},{"id":"A90","pred":"fma_id","subj":"T90","obj":"http://purl.org/sig/ont/fma/fma63915"},{"id":"A91","pred":"fma_id","subj":"T91","obj":"http://purl.org/sig/ont/fma/fma9639"}],"text":"Coronaviruses Receptor Role in human CoV disease Ocular surface (cell types) Lung\nSARS‐CoV\nSARS‐CoV‐2 ACE2 Host cell receptor and essential for infection + (conjunctival epithelium and fibroblasts; corneal epithelium) 31 + (airway epithelia)32, 33\nTMPRSS2 Primes spike protein for binding to ACE2 – + (airway epithelium) 34\nCD209 Cell‐to‐cell viral transfer + (corneal dendritic cells) 35 + (alveola macrophages) 36\nMERS‐CoV CD26 Host cell receptor and essential for infection +/− (conjunctival vascular endothelium) 37 + (lung epithelia and endothelia) 38\nCD66e Co‐receptor +/− (palpebral conjunctiva) 39 + (bronchial and alveolar epithelium) 32"}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T12","span":{"begin":81,"end":85},"obj":"Body_part"},{"id":"T13","span":{"begin":177,"end":187},"obj":"Body_part"},{"id":"T14","span":{"begin":205,"end":223},"obj":"Body_part"},{"id":"T15","span":{"begin":213,"end":223},"obj":"Body_part"},{"id":"T16","span":{"begin":239,"end":248},"obj":"Body_part"},{"id":"T17","span":{"begin":320,"end":330},"obj":"Body_part"},{"id":"T18","span":{"begin":521,"end":532},"obj":"Body_part"},{"id":"T19","span":{"begin":541,"end":545},"obj":"Body_part"},{"id":"T20","span":{"begin":546,"end":555},"obj":"Body_part"},{"id":"T21","span":{"begin":600,"end":621},"obj":"Body_part"},{"id":"T22","span":{"begin":610,"end":621},"obj":"Body_part"},{"id":"T23","span":{"begin":653,"end":663},"obj":"Body_part"}],"attributes":[{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0001772"},{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"A18","pred":"uberon_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"A19","pred":"uberon_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0001812"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0000483"}],"text":"Coronaviruses Receptor Role in human CoV disease Ocular surface (cell types) Lung\nSARS‐CoV\nSARS‐CoV‐2 ACE2 Host cell receptor and essential for infection + (conjunctival epithelium and fibroblasts; corneal epithelium) 31 + (airway epithelia)32, 33\nTMPRSS2 Primes spike protein for binding to ACE2 – + (airway epithelium) 34\nCD209 Cell‐to‐cell viral transfer + (corneal dendritic cells) 35 + (alveola macrophages) 36\nMERS‐CoV CD26 Host cell receptor and essential for infection +/− (conjunctival vascular endothelium) 37 + (lung epithelia and endothelia) 38\nCD66e Co‐receptor +/− (palpebral conjunctiva) 39 + (bronchial and alveolar epithelium) 32"}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T60","span":{"begin":86,"end":90},"obj":"Disease"},{"id":"T61","span":{"begin":95,"end":99},"obj":"Disease"},{"id":"T62","span":{"begin":150,"end":159},"obj":"Disease"},{"id":"T63","span":{"begin":483,"end":492},"obj":"Disease"}],"attributes":[{"id":"A60","pred":"mondo_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A61","pred":"mondo_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A62","pred":"mondo_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A63","pred":"mondo_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Coronaviruses Receptor Role in human CoV disease Ocular surface (cell types) Lung\nSARS‐CoV\nSARS‐CoV‐2 ACE2 Host cell receptor and essential for infection + (conjunctival epithelium and fibroblasts; corneal epithelium) 31 + (airway epithelia)32, 33\nTMPRSS2 Primes spike protein for binding to ACE2 – + (airway epithelium) 34\nCD209 Cell‐to‐cell viral transfer + (corneal dendritic cells) 35 + (alveola macrophages) 36\nMERS‐CoV CD26 Host cell receptor and essential for infection +/− (conjunctival vascular endothelium) 37 + (lung epithelia and endothelia) 38\nCD66e Co‐receptor +/− (palpebral conjunctiva) 39 + (bronchial and alveolar epithelium) 32"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T102","span":{"begin":33,"end":38},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T103","span":{"begin":68,"end":78},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T104","span":{"begin":81,"end":85},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T105","span":{"begin":81,"end":85},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T106","span":{"begin":118,"end":122},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T107","span":{"begin":177,"end":187},"obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"T108","span":{"begin":192,"end":203},"obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"T109","span":{"begin":213,"end":223},"obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"T110","span":{"begin":232,"end":238},"obj":"http://purl.obolibrary.org/obo/UBERON_0001005"},{"id":"T111","span":{"begin":313,"end":319},"obj":"http://purl.obolibrary.org/obo/UBERON_0001005"},{"id":"T112","span":{"begin":320,"end":330},"obj":"http://purl.obolibrary.org/obo/UBERON_0000483"},{"id":"T113","span":{"begin":332,"end":334},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T114","span":{"begin":342,"end":346},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T115","span":{"begin":350,"end":354},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T116","span":{"begin":382,"end":397},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T117","span":{"begin":399,"end":401},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T118","span":{"begin":427,"end":429},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"},{"id":"T119","span":{"begin":451,"end":455},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T120","span":{"begin":521,"end":532},"obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"T121","span":{"begin":541,"end":545},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T122","span":{"begin":541,"end":545},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T123","span":{"begin":610,"end":621},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T124","span":{"begin":610,"end":621},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T125","span":{"begin":653,"end":663},"obj":"http://purl.obolibrary.org/obo/UBERON_0000483"}],"text":"Coronaviruses Receptor Role in human CoV disease Ocular surface (cell types) Lung\nSARS‐CoV\nSARS‐CoV‐2 ACE2 Host cell receptor and essential for infection + (conjunctival epithelium and fibroblasts; corneal epithelium) 31 + (airway epithelia)32, 33\nTMPRSS2 Primes spike protein for binding to ACE2 – + (airway epithelium) 34\nCD209 Cell‐to‐cell viral transfer + (corneal dendritic cells) 35 + (alveola macrophages) 36\nMERS‐CoV CD26 Host cell receptor and essential for infection +/− (conjunctival vascular endothelium) 37 + (lung epithelia and endothelia) 38\nCD66e Co‐receptor +/− (palpebral conjunctiva) 39 + (bronchial and alveolar epithelium) 32"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T42","span":{"begin":278,"end":285},"obj":"Chemical"},{"id":"T43","span":{"begin":582,"end":584},"obj":"Chemical"}],"attributes":[{"id":"A42","pred":"chebi_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_27638"}],"text":"Coronaviruses Receptor Role in human CoV disease Ocular surface (cell types) Lung\nSARS‐CoV\nSARS‐CoV‐2 ACE2 Host cell receptor and essential for infection + (conjunctival epithelium and fibroblasts; corneal epithelium) 31 + (airway epithelia)32, 33\nTMPRSS2 Primes spike protein for binding to ACE2 – + (airway epithelium) 34\nCD209 Cell‐to‐cell viral transfer + (corneal dendritic cells) 35 + (alveola macrophages) 36\nMERS‐CoV CD26 Host cell receptor and essential for infection +/− (conjunctival vascular endothelium) 37 + (lung epithelia and endothelia) 38\nCD66e Co‐receptor +/− (palpebral conjunctiva) 39 + (bronchial and alveolar epithelium) 32"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T68","span":{"begin":0,"end":85},"obj":"Sentence"},{"id":"T69","span":{"begin":86,"end":94},"obj":"Sentence"},{"id":"T70","span":{"begin":95,"end":255},"obj":"Sentence"},{"id":"T71","span":{"begin":256,"end":334},"obj":"Sentence"},{"id":"T72","span":{"begin":335,"end":429},"obj":"Sentence"},{"id":"T73","span":{"begin":430,"end":574},"obj":"Sentence"},{"id":"T74","span":{"begin":575,"end":667},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Coronaviruses Receptor Role in human CoV disease Ocular surface (cell types) Lung\nSARS‐CoV\nSARS‐CoV‐2 ACE2 Host cell receptor and essential for infection + (conjunctival epithelium and fibroblasts; corneal epithelium) 31 + (airway epithelia)32, 33\nTMPRSS2 Primes spike protein for binding to ACE2 – + (airway epithelium) 34\nCD209 Cell‐to‐cell viral transfer + (corneal dendritic cells) 35 + (alveola macrophages) 36\nMERS‐CoV CD26 Host cell receptor and essential for infection +/− (conjunctival vascular endothelium) 37 + (lung epithelia and endothelia) 38\nCD66e Co‐receptor +/− (palpebral conjunctiva) 39 + (bronchial and alveolar epithelium) 32"}